Samir Jawhara (0000-0002-2759-975X)

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Researcher in Lille University Hospital, France (CNRS-UMR 8576, Inserm U1285). I was a research fellow in Cleveland Clinic (Cleveland, OH), before returning to Lille University Hospital in 2012. I received my Ph.D. in immunology-microbiology in 2006 from Lille University. I am interested in how the human pathogenic yeast Candida albicans may manipulate host innate immune pathways during the intestinal inflammation to cause disease.

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Université Lille 2 Droit et Santé: Lille, Hauts-de-France, FR

2016-04-07 to 2016-04-07 | HDR

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Samir Jawhara

https://orcid.org/0000-0002-2759-975X

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Education and qualifications (2)

Université Lille 2 Droit et Santé: Lille, Hauts-de-France, FR

Université Lille 2 Droit et Santé: Lille, Hauts-de-France, FR

Works (48)

How Do Polyphenol-Rich Foods Prevent Oxidative Stress and Maintain Gut Health?

Role of Bacteria-Derived Exopolysaccharides in Inflammatory Bowel Disease with a Special Focus on <i>Cyanobacterial</i> Exopolysaccharides

Natural Compounds with Antifungal Properties against <i>Candida albicans</i> and Identification of Hinokitiol as a Promising Antifungal Drug

Anti-<i>Malassezia</i> Drug Candidates Based on Virulence Factors of Malassezia-Associated Diseases

Antifungal Properties of Hydrazine-Based Compounds against <i>Candida albicans</i>

Healthy Diet and Lifestyle Improve the Gut Microbiota and Help Combat Fungal Infection

Editorial of Special Issue “Human Pathogenic Fungi: Host–Pathogen Interactions and Virulence”

Oleic Acid and Palmitic Acid from <i>Bacteroides thetaiotaomicron</i> and <i>Lactobacillus johnsonii</i> Exhibit Anti-Inflammatory and Antifungal Properties

How Gut Bacterial Dysbiosis Can Promote <i>Candida albicans</i> Overgrowth during Colonic Inflammation

Identification of fungal trehalose for the diagnosis of invasive candidiasis by mass spectrometry

Two New Compounds Containing Pyridinone or Triazine Heterocycles Have Antifungal Properties against <i>Candida albicans</i>

Dissection of the anti-Candida albicans mannan immune response using synthetic oligomannosides reveals unique properties of β-1,2 mannotriose protective epitopes.

A Pilot Clinical Study on Post-Operative Recurrence Provides Biological Clues for a Role of <i>Candida</i> Yeasts and Fluconazole in Crohn’s Disease

Promising Drug Candidates and New Strategies for Fighting against the Emerging Superbug <i>Candida auris</i>

Bacteroides thetaiotaomicron and Lactobacillus johnsonii modulate intestinal inflammation and eliminate fungi via enzymatic hydrolysis of the fungal cell wall

H89 Treatment Reduces Intestinal Inflammation and <i>Candida albicans</i> Overgrowth in Mice

How to boost the immune defence prior to respiratory virus infections with the special focus on coronavirus infections.

Can Drinking Microfiltered Raw Immune Milk From Cows Immunized Against SARS-CoV-2 Provide Short-Term Protection Against COVID-19?

How Fungal Glycans Modulate Platelet Activation via Toll-Like Receptors Contributing to the Escape of <i>Candida albicans</i> from the Immune Response

Could Intravenous Immunoglobulin Collected from Recovered Coronavirus Patients Protect against COVID-19 and Strengthen the Immune System of New Patients?

New efficient eco-friendly supported catalysts for the synthesis of amides with antioxidant and anti-inflammatory properties.

Fungal Chitin Reduces Platelet Activation Mediated via TLR8 Stimulation.

Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease.

Intravenous Immunoglobulin Therapy Eliminates <i>Candida</i> <i>albicans</i> and Maintains Intestinal Homeostasis in a Murine Model of Dextran Sulfate Sodium-Induced Colitis

A Small Aromatic Compound Has Antifungal Properties and Potential Anti-Inflammatory Effects against Intestinal Inflammation

A decrease in anaerobic bacteria promotes Candida glabrata overgrowth while β-glucan treatment restores the gut microbiota and attenuates colitis.

Remodeling of the Candida glabrata cell wall in the gastrointestinal tract affects the gut microbiota and the immune response.

Uric acid levels are independent of anti-Saccharomyces cerevisiae antibodies (ASCA) in Crohn's disease: A reappraisal of the role of S. cerevisiae in this setting.

Role of TLR1, TLR2 and TLR6 in the modulation of intestinal inflammation and Candida albicans elimination.

Distinct Effects of Integrins αXβ2 and αMβ2 on Leukocyte Subpopulations during Inflammation and Antimicrobial Responses.

Corrigendum: Polymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn's Disease Patients.

Polymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn's Disease Patients.

Short fungal fractions of β-1,3 glucans affect platelet activation.

Role of mannose-binding lectin in intestinal homeostasis and fungal elimination.

Preliminary evidence for a serum disaccharide signature of invasive Candida albicans infection detected by MALDI Mass Spectrometry.

Genetic diversity among Candida albicans isolates associated with vertical transmission in preterm triplets.

Candida albicans airway exposure primes the lung innate immune response against Pseudomonas aeruginosa infection through innate lymphoid cell recruitment and interleukin-22-associated mucosal response.

Modulation of intestinal inflammation by yeasts and cell wall extracts: strain dependence and unexpected anti-inflammatory role of glucan fractions.

Mannose-binding lectin levels and variation during invasive candidiasis.

Integrin αXβ₂ is a leukocyte receptor for Candida albicans and is essential for protection against fungal infections.

Murine model of dextran sulfate sodium-induced colitis reveals Candida glabrata virulence and contribution of β-mannosyltransferases.

Short term Candida albicans colonization reduces Pseudomonas aeruginosa-related lung injury and bacterial burden in a murine model.

Regulation of innate immune response to Candida albicans infections by αMβ2-Pra1p interaction.

Yeasts: neglected pathogens.

Colonization of mice by Candida albicans is promoted by chemically induced colitis and augments inflammatory responses through galectin-3.

Saccharomyces boulardii decreases inflammation and intestinal colonization by Candida albicans in a mouse model of chemically-induced colitis.

Monitoring of bactericidal action of laser by in vivo imaging of bioluminescent E. coli in a cutaneous wound infection.

In vivo imaging of bioluminescent Escherichia coli in a cutaneous wound infection model for evaluation of an antibiotic therapy.

Peer review (1 review for 1 publication/grant)