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Københavns Universitet: København K, DK

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University of Copenhagen

Education and qualifications (1)

University of Copenhagen: Copenhagen, DK

2016-09-15 to present | PhD (Department of Drug Design & Pharmacology)
Education
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Emil Märcher-Rørsted

Works (12)

Bitopic Ligands Support the Presence of a Metastable Binding Site at the β2 Adrenergic Receptor

Journal of Medicinal Chemistry
2024-07-11 | Journal article
DOI: 10.1021/acs.jmedchem.4c00578
Contributors: Birgit Isabel Gaiser; Mia Danielsen; Xinyu Xu; Kira Røpke Jørgensen; Philipp Fronik; Emil Märcher-Rørsted; Tomasz M. Wróbel; Xiangyu Liu; Jesper Mosolff Mathiesen; Daniel Sejer Pedersen
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Crossref
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Discovery and Structure–Activity Relationships of 2,5-Dimethoxyphenylpiperidines as Selective Serotonin 5-HT2A Receptor Agonists

Journal of Medicinal Chemistry
2024-05-09 | Journal article
DOI: 10.1021/acs.jmedchem.4c00082
Contributors: Emil M. Ro̷rsted; Anders A. Jensen; Gints Smits; Karla Frydenvang; Jesper L. Kristensen
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Crossref
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In Vitro and In Vivo Evaluation of Pellotine

ACS Pharmacology & Translational Science
2023 | Journal article | Author
DOI: 10.1021/acsptsci.3c00142
SOURCE-WORK-ID:

e6536f3d-adf6-42e0-9a1f-d2e9ca70eee5

PMID: 37854625
EID:

2-s2.0-85175071802
Contributors: Christian B M Poulie; Camilla B Chan; Aleksandra Parka; Magnus Lettorp; Josephine Vos; Amanda Raaschou; Eline Pottie; Mikkel S Bundgaard; Louis M E Sørensen; Claudia R Cecchi et al.
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University of Copenhagen

Introducing Conformational Restraints on 25CN-NBOH: A Selective 5-HT2A Receptor Agonist

ACS Medicinal Chemistry Letters
2023-03-09 | Journal article
DOI: 10.1021/acsmedchemlett.3c00014
Contributors: Emil Marcher-Rørsted; Jitka Nykodemová; Kasper Harpsøe; Anders A. Jensen; Jesper L. Kristensen
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Crossref
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25CN‐NBOH: A Selective Agonist for in vitro and in vivo Investigations of the Serotonin 2A Receptor

ChemMedChem
2021-11-05 | Journal article
DOI: 10.1002/cmdc.202100395
Part of ISSN: 1860-7179
Part of ISSN: 1860-7187
Contributors: Emil Märcher Rørsted; Anders A. Jensen; Jesper L. Kristensen
Source: Self-asserted source
Emil Märcher-Rørsted

An Improved, Scalable Synthesis of the Selective Serotonin 2A Receptor Agonist 25CN-NBOH

SynOpen
2021-06 | Journal article
DOI: 10.1055/a-1524-4439
Contributors: Jesper L. Kristensen; Emil Märcher-Rørsted; Jitka Nykodemová
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Crossref
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Erythrina Alkaloid Analogues as nAChR Antagonists–A Flexible Platform for Leads in Drug Discovery

The Journal of Organic Chemistry
2021-06-18 | Journal article
DOI: 10.1021/acs.joc.1c00707
Contributors: Sebastian Clementson; Sergio Armentia Matheu; Emil Märcher Rørsted; Henrik Pedersen; Anders A. Jensen; Rasmus P. Clausen; Paulo Vital; Emil Glibstrup; Mikkel Jessing; Jesper L. Kristensen
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Crossref
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The selective 5-HT2A receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH

Biochemical Pharmacology
2020-07 | Journal article
DOI: 10.1016/j.bcp.2020.113979
Part of ISSN: 0006-2952
Contributors: Anders A. Jensen; Adam L. Halberstadt; Emil Märcher-Rørsted; Anna U. Odland; Muhammad Chatha; Nikolaj Speth; Gudrun Liebscher; Martin Hansen; Hans Bräuner-Osborne; Mikael Palner et al.
Source: Self-asserted source
Emil Märcher-Rørsted
grade
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Investigation of the 2,5-Dimethoxy Motif in Phenethylamine Serotonin 2A Receptor Agonists

ACS Chemical Neuroscience
2020-05-06 | Journal article
DOI: 10.1021/acschemneuro.0c00129
Contributors: Emil Marcher-Rørsted; Adam L. Halberstadt; Adam K. Klein; Muhammad Chatha; Simon Jademyr; Anders A. Jensen; Jesper L. Kristensen
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Crossref
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Probing the Existence of a Metastable Binding Site at the β2-Adrenergic Receptor with Homobivalent Bitopic Ligands

Journal of Medicinal Chemistry
2019-09-12 | Journal article
DOI: 10.1021/acs.jmedchem.9b00595
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Emil Märcher-Rørsted
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Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics

Neuropharmacology
2019-07 | Journal article
DOI: 10.1016/j.neuropharm.2019.107718
Part of ISSN: 0028-3908
Source: Self-asserted source
Emil Märcher-Rørsted
grade
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Structure-activity-relationship study of N-acyl-N-phenylpiperazines as potential inhibitors of the excitatory amino acid transporters (EAATs): Improving the potency of a micromolar screening hit is not truism

SpringerPlus
2013 | Journal article | Author
DOI: 10.1186/2193-1801-2-112
SOURCE-WORK-ID:

b50e5e03-2559-4afb-8d17-313208f42a42

EID:

2-s2.0-84876513030
Contributors: Tri Hien Viet Huynh; Charles Sylvain Demmer; Bjarke Abrahamsen; Emil Märcher-Rørsted; M Frykman; Anders A. Jensen; Lennart Bunch
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University of Copenhagen
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