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Employment (5)

Leiden University Medical Center: Leiden, NL

2020-05-01 to present | Assistant Professor (Human Genetics)
Employment
Source: Self-asserted source
Jessica de Greef

Leiden University Medical Center: Leiden, NL

2017-08-01 to 2020-04-30 | Senior Researcher (Human Genetics)
Employment
Source: Self-asserted source
Jessica de Greef

Leiden University Medical Center: Leiden, NL

2015-04-01 to 2017-07-31 | Researcher (Human Genetics)
Employment
Source: Self-asserted source
Jessica de Greef

University of Iowa Hospitals and Clinics: Iowa City, IA, US

2010-11-01 to 2015-03-31 | Postdoctoral Research Scholar (Molecular Physiology and Biophysics)
Employment
Source: Self-asserted source
Jessica de Greef

Leiden University Medical Center: Leiden, NL

2008-09-01 to 2010-08-31 | Researcher (Human Genetics)
Employment
Source: Self-asserted source
Jessica de Greef

Education and qualifications (2)

Leiden University: Leiden, NL

2004-09-01 to 2008-08-31 | PhD student (Human Genetics)
Qualification
Source: Self-asserted source
Jessica de Greef

Leiden University: Leiden, NL

1999-09-01 to 2004-08-31 | MSc, Biomedical Sciences
Qualification
Source: Self-asserted source
Jessica de Greef

Funding (3)

Hypermorphic SMCHD1 variants

2018-07 to 2021-10 | Grant
FSHD Society (Randolph, US)
Source: Self-asserted source
Jessica de Greef

Function of DUX4 in skeletal muscle and non-muscle tissues

2018-07 to 2020-09 | Grant
European Commission (Brussels, BE)
Source: Self-asserted source
Jessica de Greef

De rol van DUX4 in het afweersysteem bij FSHD

2017-09 to 2021-12 | Grant
Prinses Beatrix Spierfonds (Den Haag, NL)
Source: Self-asserted source
Jessica de Greef

Works (31)

USP18 is an essential regulator of muscle cell differentiation and maturation

Cell Death & Disease
2023-03-31 | Journal article
DOI: 10.1038/s41419-023-05725-z
Contributors: Cyriel Sebastiaan Olie; Adán Pinto-Fernández; Andreas Damianou; Iolanda Vendrell; Hailiang Mei; Bianca den Hamer; Erik van der Wal; Jessica C. de Greef; Vered Raz; Benedikt M. Kessler
Source: check_circle
Crossref

Facioscapulohumeral muscular dystrophy: the road to targeted therapies

Nature Reviews Neurology
2023-02 | Journal article
DOI: 10.1038/s41582-022-00762-2
Contributors: Mara S. Tihaya; Karlien Mul; Judit Balog; Jessica C. de Greef; Stephen J. Tapscott; Rabi Tawil; Jeffrey M. Statland; Silvère M. van der Maarel
Source: check_circle
Crossref

Meeting report: the 2021 FSHD International Research Congress

Skeletal Muscle
2022-12 | Journal article
DOI: 10.1186/s13395-022-00287-8
Part of ISSN: 2044-5040
Source: Self-asserted source
Jessica de Greef

USP18 is an essential regulator of muscle cell differentiation and maturation

2022-11-14 | Preprint
DOI: 10.21203/rs.3.rs-2172567/v1
Contributors: Cyriel Olie; Adán Pinto-Fernández; Andreas Damianou; Iolanda Vendrell; Hailiang Mei; Bianca den Hamer; Erik van der Wal; Jessica de Greef; vered raz; Benedikt Kessler
Source: check_circle
Crossref

USP18 is an essential regulator of muscle cell differentiation and maturation

2022-04-01 | Preprint
DOI: 10.1101/2022.04.01.486741
Contributors: Cyriel Sebastiaan Olie; Adán Pinto-Fernández; Andreas Damianou; Iolanda Vendrell; Hailiang Mei; Bianca den Hamer; Erik van der Wal; Jessica C. de Greef; Eleonora Aronica; Vered Raz et al.
Source: check_circle
Crossref

Author Correction: Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

Scientific Reports
2021-12 | Journal article
DOI: 10.1038/s41598-021-85459-0
Part of ISSN: 2045-2322
Source: Self-asserted source
Jessica de Greef

Systemic delivery of a DUX4-targeting antisense oligonucleotide to treat facioscapulohumeral muscular dystrophy

Molecular Therapy - Nucleic Acids
2021-12 | Journal article
DOI: 10.1016/j.omtn.2021.09.010
Part of ISSN: 2162-2531
Source: Self-asserted source
Jessica de Greef

Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice

Skeletal Muscle
2020-12 | Journal article
DOI: 10.1186/s13395-020-00247-0
Contributors: Linde F. Bouwman; Bianca den Hamer; Elwin P. Verveer; Lente J. S. Lerink; Yvonne D. Krom; Silvère M. van der Maarel; Jessica C. de Greef
Source: check_circle
Crossref

The prospects of targeting DUX4 in facioscapulohumeral muscular dystrophy

Current Opinion in Neurology
2020-10 | Journal article
DOI: 10.1097/wco.0000000000000849
Part of ISSN: 1350-7540
Part of ISSN: 1473-6551
Source: Self-asserted source
Jessica de Greef

Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability.

Scientific reports
2020-10-19 | Journal article
DOI: 10.1038/s41598-020-74676-8
PMID: 33077830
PMC: PMC7572364
Source: Self-asserted source
Jessica de Greef

Coupling 3D Printing and Novel Replica Molding for In House Fabrication of Skeletal Muscle Tissue Engineering Devices

Advanced Materials Technologies
2020-07-26 | Journal article
DOI: 10.1002/admt.202000344
Part of ISSN: 2365-709X
Part of ISSN: 2365-709X
Source: Self-asserted source
Jessica de Greef

Mouse models for muscular dystrophies: an overview

Disease Models & Mechanisms
2020-02-01 | Journal article
DOI: 10.1242/dmm.043562
Contributors: Maaike van Putten; Erin M. Lloyd; Jessica C. de Greef; Vered Raz; Raffaella Willmann; Miranda D. Grounds; Annemieke Aartsma-Rus; James Dowling; Maaike van Putten
Source: check_circle
Crossref

Generation of genetically matched hiPSC lines from two mosaic facioscapulohumeral dystrophy type 1 patients.

Stem cell research
2019-08-28 | Journal article
DOI: 10.1016/j.scr.2019.101560
PMID: 31518905
Source: Self-asserted source
Jessica de Greef

Protective role for the N-terminal domain of α-dystroglycan in Influenza A virus proliferation.

Proceedings of the National Academy of Sciences of the United States of America
2019-05-16 | Journal article
DOI: 10.1073/pnas.1904493116
PMID: 31097590
PMC: PMC6561248
Source: Self-asserted source
Jessica de Greef

Smchd1 haploinsufficiency exacerbates the phenotype of a transgenic FSHD1 mouse model.

Human molecular genetics
2018-02-01 | Journal article
DOI: 10.1093/hmg/ddx437
PMID: 29281018
PMC: PMC5886298
Source: Self-asserted source
Jessica de Greef

Corrigendum: Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome.

Nature communications
2016-06-22 | Journal article
DOI: 10.1038/ncomms12003
PMID: 27328760
PMC: PMC4917957
Source: Self-asserted source
Jessica de Greef

Collagen VI deficiency reduces muscle pathology, but does not improve muscle function, in the γ-sarcoglycan-null mouse.

Human molecular genetics
2016-01-24 | Journal article
DOI: 10.1093/hmg/ddw018
PMID: 26908621
PMC: PMC4787905
Source: Self-asserted source
Jessica de Greef

Mutations in CDCA7 and HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome.

Nature communications
2015-07-28 | Journal article
DOI: 10.1038/ncomms8870
PMID: 26216346
PMC: PMC4519989
Source: Self-asserted source
Jessica de Greef

Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeral muscular dystrophy type 2.

Nature genetics
2012-11-11 | Journal article
DOI: 10.1038/ng.2454
PMID: 23143600
PMC: PMC3671095
Source: Self-asserted source
Jessica de Greef

Correlation analysis of clinical parameters with epigenetic modifications in the DUX4 promoter in FSHD.

Epigenetics
2012-06-01 | Journal article
DOI: 10.4161/epi.20001
PMID: 22522912
PMC: PMC3398987
Source: Self-asserted source
Jessica de Greef

Patients with a phenotype consistent with facioscapulohumeral muscular dystrophy display genetic and epigenetic heterogeneity.

Journal of medical genetics
2011-10-07 | Journal article
DOI: 10.1136/jmedgenet-2011-100101
PMID: 21984748
PMC: PMC3560331
Source: Self-asserted source
Jessica de Greef

Mutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2.

American journal of human genetics
2011-05-19 | Journal article
DOI: 10.1016/j.ajhg.2011.04.018
PMID: 21596365
PMC: PMC3113345
Source: Self-asserted source
Jessica de Greef

Clinical features of facioscapulohumeral muscular dystrophy 2.

Neurology
2010-10-01 | Journal article
DOI: 10.1212/WNL.0b013e3181f96175
PMID: 20975055
PMC: PMC2974464
Source: Self-asserted source
Jessica de Greef

Analysis of allele-specific RNA transcription in FSHD by RNA-DNA FISH in single myonuclei.

European journal of human genetics : EJHG
2009-11-04 | Journal article
DOI: 10.1038/ejhg.2009.183
PMID: 19888305
PMC: PMC2843500
Source: Self-asserted source
Jessica de Greef

Common epigenetic changes of D4Z4 in contraction-dependent and contraction-independent FSHD.

Human mutation
2009-10-01 | Journal article
DOI: 10.1002/humu.21091
PMID: 19728363
Source: Self-asserted source
Jessica de Greef

Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD).

PLoS genetics
2009-07-10 | Journal article
DOI: 10.1371/journal.pgen.1000559
PMID: 19593370
PMC: PMC2700282
Source: Self-asserted source
Jessica de Greef

Epigenetic mechanisms of facioscapulohumeral muscular dystrophy.

Mutation research
2008-08-03 | Journal article
DOI: 10.1016/j.mrfmmm.2008.07.011
PMID: 18723032
PMC: PMC2650037
Source: Self-asserted source
Jessica de Greef

Clinical spectrum of immunodeficiency, centromeric instability and facial dysmorphism (ICF syndrome).

Journal of medical genetics
2007-09-24 | Journal article
DOI: 10.1136/jmg.2007.053397
PMID: 17893117
Source: Self-asserted source
Jessica de Greef

Hypomethylation is restricted to the D4Z4 repeat array in phenotypic FSHD.

Neurology
2007-09-01 | Journal article
DOI: 10.1212/01.wnl.0000271391.44352.fe
PMID: 17785671
Source: Self-asserted source
Jessica de Greef

ICF syndrome: high variability of the chromosomal phenotype and association with classical Hodgkin lymphoma.

American journal of medical genetics. Part A
2007-09-01 | Journal article
DOI: 10.1002/ajmg.a.31885
PMID: 17702009
Source: Self-asserted source
Jessica de Greef

No effect of folic acid and methionine supplementation on D4Z4 methylation in patients with facioscapulohumeral muscular dystrophy.

Neuromuscular disorders : NMD
2006-09-26 | Journal article
DOI: 10.1016/j.nmd.2006.08.005
PMID: 17005397
Source: Self-asserted source
Jessica de Greef

Peer review (5 reviews for 4 publications/grants)

Review activity for Cell death and disease. (1)
Review activity for Heliyon. (2)
Review activity for Orphanet journal of rare diseases. (1)
Review activity for PLOS genetics. (1)
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