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University of Pennsylvania: Philadelphia, PA, US

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Works (50 of 81)

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Toward a Small-Molecule Antagonist Radioligand for Positron Emission Tomography Imaging of the Mu Opioid Receptor

ACS Chemical Neuroscience
2025-03-29 | Journal article
DOI: 10.1021/acschemneuro.5c00140
Contributors: Konstantinos Plakas; Chia-Ju Hsieh; Dinahlee Saturnino Guarino; Catherine Hou; Wai-Kit Chia; Anthony Young; Alexander Schmitz; Yi-Pei Ho; Chi-Chang Weng; Hsiaoju Lee et al.
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A Small-molecule Antagonist Radiotracer for Positron Emission Tomography Imaging of the Mu Opioid Receptor

2024-10-12 | Preprint
DOI: 10.1101/2024.10.12.618019
Contributors: Konstantinos Plakas; Chia-Ju Hsieh; Dinahlee Saturnino Guarino; Catherine Hou; Wai-Kit Chia; Anthony Young; Alexander Schmitz; Yi-Pei Ho; Chi-Chang Weng; Hsiaoju Lee et al.
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Positron Emission Tomography with [18F]ROStrace Reveals Progressive Elevations in Oxidative Stress in a Mouse Model of Alpha-Synucleinopathy

International Journal of Molecular Sciences
2024-05-01 | Journal article
DOI: 10.3390/ijms25094943
Contributors: Evan Gallagher; Catherine Hou; Yi Zhu; Chia-Ju Hsieh; Hsiaoju Lee; Shihong Li; Kuiying Xu; Patrick Henderson; Rea Chroneos; Malkah Sheldon et al.
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Design and Synthesis of D3R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies

Molecules
2023-12-24 | Journal article
DOI: 10.3390/molecules29010123
Contributors: Gui-Long Tian; Chia-Ju Hsieh; Michelle Taylor; Ji Youn Lee; Robert R. Luedtke; Robert H. Mach
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A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy

Journal of Medicinal Chemistry
2023-09-14 | Journal article
DOI: 10.1021/acs.jmedchem.3c00779
Contributors: Ho Young Kim; Wai Kit Chia; Chia-Ju Hsieh; Dinahlee Saturnino Guarino; Thomas J. A. Graham; Zsofia Lengyel-Zhand; Mark Schneider; Cosette Tomita; Marshall G. Lougee; Hee Jong Kim et al.
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[18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

Clinical Cancer Research
2023-04-14 | Journal article
DOI: 10.1158/1078-0432.CCR-22-1602
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Data from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.c.6532755
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Data from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.c.6532755.v2
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S1 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632998
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S1 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632998.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S2 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632995
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S2 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632995.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S3 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632992.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S3 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632992
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S4 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632989.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S4 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632989
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S5 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632986
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S5 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632986.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S6 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632983
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S6 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632983.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Table S1 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632980
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Table S1 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632980.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Table S2 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632977.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Table S2 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-14 | Preprint
DOI: 10.1158/1078-0432.22632977
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Data from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.c.6532755.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S1 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488552
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S1 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488552.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S2 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488549
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S2 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488549.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S3 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488546
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S3 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488546.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S4 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488543
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S4 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488543.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S5 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488537
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S5 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488537.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S6 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488534
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Figure S6 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488534.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Table S1 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488531.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Table S1 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488531
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Table S2 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488528.v1
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Supplemental Table S2 from [<sup>18</sup>F]FluorThanatrace ([<sup>18</sup>F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

2023-04-01 | Preprint
DOI: 10.1158/1078-0432.22488528
Contributors: Austin R. Pantel; Sarah B. Gitto; Mehran Makvandi; Hyoung Kim; Sergey Medvedv; Joanna K. Weeks; Drew A. Torigian; Chia-Ju Hsieh; Benjamin Ferman; Nawar A. Latif et al.
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Computational Chemistry for the Identification of Lead Compounds for Radiotracer Development

Pharmaceuticals
2023-02-18 | Journal article
DOI: 10.3390/ph16020317
Contributors: Chia-Ju Hsieh; Sam Giannakoulias; E. James Petersson; Robert H. Mach
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Design and Synthesis of Conformationally Flexible Scaffold as Bitopic Ligands for Potent D3-Selective Antagonists

International Journal of Molecular Sciences
2022-12-27 | Journal article
DOI: 10.3390/ijms24010432
Contributors: Ho Young Kim; Ji Youn Lee; Chia-Ju Hsieh; Michelle Taylor; Robert R. Luedtke; Robert H. Mach
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Exploration of Diazaspiro Cores as Piperazine Bioisosteres in the Development of σ2 Receptor Ligands

International Journal of Molecular Sciences
2022-07-27 | Journal article
DOI: 10.3390/ijms23158259
Contributors: Kuiying Xu; Chia-Ju Hsieh; Ji Youn Lee; Aladdin Riad; Nicholas J. Izzo; Gary Look; Susan Catalano; Robert H. Mach
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Screening of σ2 Receptor Ligands and In Vivo Evaluation of 11C-Labeled 6,7-Dimethoxy-2-[4-(4-methoxyphenyl)butan-2-yl]-1,2,3,4-tetrahydroisoquinoline for Potential Use as a σ2 Receptor Brain PET Tracer

Journal of Medicinal Chemistry
2022-04-28 | Journal article
DOI: 10.1021/acs.jmedchem.2c00191
Contributors: Ho Young Kim; Ji Youn Lee; Chia-Ju Hsieh; Aladdin Riad; Nicholas J. Izzo; Susan M. Catalano; Thomas J. A. Graham; Robert H. Mach
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Poly (ADP-ribose) Interacts With Phosphorylated α-Synuclein in Post Mortem PD Samples

Frontiers in Aging Neuroscience
2021 | Journal article
DOI: 10.3389/fnagi.2021.704041
EID:

2-s2.0-85108991689

Part of ISSN: 16634365
Contributors: Puentes, L.N.; Lengyel-Zhand, Z.; Lee, J.Y.; Hsieh, C.-J.; Schneider, M.E.; Edwards, K.J.; Luk, K.C.; Lee, V.M.Y.; Trojanowski, J.Q.; Mach, R.H.
Source: Self-asserted source
Chia-Ju Hsieh via Scopus - Elsevier

Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods

Biomolecules
2021-04-02 | Journal article
DOI: 10.3390/biom11040529
Contributors: Chia-Ju Hsieh; Aladdin Riad; Ji Youn Lee; Kristoffer Sahlholm; Kuiying Xu; Robert R. Luedtke; Robert H. Mach
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Development of a novel task-oriented rehabilitation program using a bimanual exoskeleton robotic hand

Journal of Visualized Experiments
2020 | Journal article
DOI: 10.3791/61057
EID:

2-s2.0-85085381289

Part of ISSN: 1940087X
Contributors: Chen, Y.-M.; Lai, S.-S.; Pei, Y.-C.; Hsieh, C.-J.; Chang, W.-H.
Source: Self-asserted source
Chia-Ju Hsieh via Scopus - Elsevier

Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening

Chemical Science
2020 | Journal article
DOI: 10.1039/D0SC02159H
Contributors: John J. Ferrie; Zsofia Lengyel-Zhand; Bieneke Janssen; Marshall G. Lougee; Sam Giannakoulias; Chia-Ju Hsieh; Vinayak Vishnu Pagar; Chi-Chang Weng; Hong Xu; Thomas J. A. Graham et al.
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Crossref
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Poly (ADP-ribose) induces α-synuclein aggregation in neuronal-like cells and interacts with phosphorylated α-synuclein in post mortem PD samples

bioRxiv
2020 | Other
DOI: 10.1101/2020.04.08.032250
EID:

2-s2.0-85098900867

Part of ISSN: 26928205
Contributors: Puentes, L.N.; Lengyel-Zhand, Z.; Lee, J.Y.; Hsieh, C.-J.; Schneider, M.E.; Edwards, K.J.; Luk, K.C.; Lee, V.M.-Y.; Trojanowski, J.Q.; Mach, R.H.
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Chia-Ju Hsieh via Scopus - Elsevier
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