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Employment (1)

Agency for Science, Technology and Research: Singapore, SG

Senior Principal Investigator
Employment
Source: Self-asserted source
Florent Ginhoux

Education and qualifications (1)

UPMC: Paris, Ile de France, FR

Education
Source: Self-asserted source
Florent Ginhoux

Works (47)

Defining myeloid-derived suppressor cells

Nature Reviews Immunology
2024-12 | Journal article
Contributors: Leila Akkari; Ido Amit; Vincenzo Bronte; Zvi G. Fridlender; Dmitry I. Gabrilovich; Florent Ginhoux; Catherine C. Hedrick; Suzanne Ostrand-Rosenberg
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Host and rabies virus gene expression is shaped by human brain cell type and reveals a preexisting pro-viral transcriptional state in astrocytes

2024-12-20 | Preprint
Contributors: Lena Feige; Karl Young; Juan Pablo Cerapio; Tatsuya Kozaki; Lauriane Kergoat; Valentina Libri; Florent Ginhoux; Milena Hasan; Lamya Ben Ameur; Gregory Chin et al.
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Charting spatial ligand-target activity using Renoir

2024-11-25 | Preprint
Contributors: Hamim Zafar; Narein Rao; Tanush Kumar; Rhea Pai; Archita Mishra; Florent Ginhoux; Jerry Chan; Ankur Sharma
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Induced pluripotent stem cell-derived macrophages as a platform for modelling human disease

Nature Reviews Immunology
2024-09-27 | Journal article
Contributors: Satish Kumar Tiwari; Wei Jie Wong; Marco Moreira; Claudia Pasqualini; Florent Ginhoux
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A single-cell pan-cancer analysis to show the variability of tumor-infiltrating myeloid cells in immune checkpoint blockade

Nature Communications
2024-07-21 | Journal article
Contributors: Weiyuan Li; Lu Pan; Weifeng Hong; Florent Ginhoux; Xuan Zhang; Chunjie Xiao; Xuexin Li
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Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance

2024-05-10 | Preprint
Contributors: Henna Lehtonen; Heli Jokela; Julian Hofmann; Lauriina Tola; Arfa Mehmood; Florent Ginhoux; Burkhard Becher; Melanie Greter; Marko Salmi; Heidi Gerke et al.
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Roles of macrophages in tumor development: a spatiotemporal perspective

Cellular & Molecular Immunology
2023-07-10 | Journal article
Contributors: Mathilde Bied; William W. Ho; Florent Ginhoux; Camille Blériot
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Brain macrophage development, diversity and dysregulation in health and disease

Cellular & Molecular Immunology
2023-06-26 | Journal article
Contributors: Aymeric Silvin; Jiawen Qian; Florent Ginhoux
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Reply to ‘Reclassification of plasmacytoid dendritic cells as innate lymphocytes is premature’

Nature Reviews Immunology
2023-05 | Journal article
Contributors: Loems Ziegler-Heitbrock; Toshiaki Ohteki; Florent Ginhoux; Ken Shortman; Hergen Spits
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Proteasome inhibitor bortezomib stabilizes and activates p53 in hematopoietic stem/progenitors and double-negative T cells in vivo

Proceedings of the National Academy of Sciences
2023-03-28 | Journal article
Contributors: Yuezhen Xue; Boris San Luis; Regine J. Dress; Katzrin Binte Ahmad Murad; Florent Ginhoux; Nick Barker; David Lane
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New perspectives on the origins and heterogeneity of mast cells

Nature Reviews Immunology
2023-01 | Journal article
Contributors: Ashley L. St. John; Abhay P. S. Rathore; Florent Ginhoux
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Reclassifying plasmacytoid dendritic cells as innate lymphocytes

Nature Reviews Immunology
2023-01 | Journal article
Contributors: Loems Ziegler-Heitbrock; Toshiaki Ohteki; Florent Ginhoux; Ken Shortman; Hergen Spits
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Oncofetal reprogramming in tumour development and progression

Nature Reviews Cancer
2022-10 | Journal article
Contributors: Ankur Sharma; Camille Blériot; Jennifer Currenti; Florent Ginhoux
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A Western Diet Alters Skin Ceramides and Compromises the Skin Barrier in Ears

Journal of Investigative Dermatology
2022-07 | Journal article
Contributors: Kahbing Jasmine Tan; Satoshi Nakamizo; Hyeon-Cheol Lee-Okada; Reiko Sato; Zachary Chow; Saeko Nakajima; John E.A. Common; Kazuko Saeki; Takehiko Yokomizo; Florent Ginhoux et al.
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Role of adipose tissue macrophages in obesity-related disorders

Journal of Experimental Medicine
2022-07-04 | Journal article
Contributors: Svetoslav Chakarov; Camille Blériot; Florent Ginhoux
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Human dendritic cells in cancer

Science Immunology
2022-04 | Journal article
Contributors: Egle Kvedaraite; Florent Ginhoux
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Reply to ‘Comment on: Repositioning TH cell polarization from single cytokines to complex help’

Nature Immunology
2022-04 | Journal article
Contributors: Selma Tuzlak; Florent Ginhoux; Thomas Korn; Burkhard Becher
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Biology of resident tissue macrophages

Development
2022-04-15 | Journal article
Contributors: Christopher Zhe Wei Lee; Florent Ginhoux
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Insights into the role of immune cells in development and regeneration

Development
2022-04-15 | Journal article
Contributors: Florent Ginhoux; Paul Martin
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Expanding dendritic cell nomenclature in the single-cell era

Nature Reviews Immunology
2022-02 | Journal article
Contributors: Florent Ginhoux; Martin Guilliams; Miriam Merad
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IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation

Nature Immunology
2022-02 | Journal article
Contributors: Ana Amorim; Donatella De Feo; Ekaterina Friebel; Florian Ingelfinger; Cyrill Dimitri Anderfuhren; Sinduya Krishnarajah; Myrto Andreadou; Christina A. Welsh; Zhaoyuan Liu; Florent Ginhoux et al.
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Maternal Dendritic Cells Influence Fetal Allograft Response and Tolerance

2022-01-25 | Preprint
Contributors: Citra Mattar; Karthikeyan Kandasamy; Nuryanti Binti Johana; Lay Geok Tan; Yvonne Tan; Julie Yeo; Zhihui Li; Jiayu Koh; Florent Ginhoux; Jerry Chan et al.
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Repositioning TH cell polarization from single cytokines to complex help

Nature Immunology
2021-10 | Journal article
Contributors: Selma Tuzlak; Anne S. Dejean; Matteo Iannacone; Francisco J. Quintana; Ari Waisman; Florent Ginhoux; Thomas Korn; Burkhard Becher
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High-throughput single-cell quantification of hundreds of proteins using conventional flow cytometry and machine learning

Science Advances
2021-09-24 | Journal article
Contributors: Etienne Becht; Daniel Tolstrup; Charles-Antoine Dutertre; Peter A. Morawski; Daniel J. Campbell; Florent Ginhoux; Evan W. Newell; Raphael Gottardo; Mark B. Headley
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Embryonic macrophages function during early life to determine invariant natural killer T cell levels at barrier surfaces

Nature Immunology
2021-06-26 | Journal article
Contributors: Thomas Gensollen; Xi Lin; Ting Zhang; Michal Pyzik; Peter See; Jonathan N. Glickman; Florent Ginhoux; Matthew Waldor; Marko Salmi; Pia Rantakari et al.
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Genetic models of human and mouse dendritic cell development and function

Nature Reviews Immunology
2021-02 | Journal article
Contributors: David A. Anderson, III; Charles-Antoine Dutertre; Florent Ginhoux; Kenneth M. Murphy
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Water quality check: macrophages setting the standards

Cell Research
2021-01-02 | Journal article
Contributors: Camille Blériot; Zhaoyuan Liu; Florent Ginhoux
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Kidney dendritic cells: fundamental biology and functional roles in health and disease

Nature Reviews Nephrology
2020-07-05 | Journal article
Contributors: Christian Kurts; Florent Ginhoux; Ulf Panzer
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Infinity Flow: High-throughput single-cell quantification of 100s of proteins using conventional flow cytometry and machine learning

2020-06-19 | Other
Contributors: Etienne Becht; Daniel Tolstrup; Charles-Antoine Dutertre; Florent Ginhoux; Evan W. Newell; Raphael Gottardo; Mark B. Headley
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Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling

Nature Cell Biology
2020-05-01 | Journal article
Contributors: Caleb A. Dawson; Bhupinder Pal; François Vaillant; Luke C. Gandolfo; Zhaoyuan Liu; Camille Bleriot; Florent Ginhoux; Gordon K. Smyth; Geoffrey J. Lindeman; Scott N. Mueller et al.
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The coming of age of Langerhans cell histiocytosis

Nature Immunology
2020-01-12 | Journal article
Contributors: Carl E. Allen; Peter C. L. Beverley; Matthew Collin; Eli L. Diamond; R. Maarten Egeler; Florent Ginhoux; Christopher Glass; Milen Minkov; Barrett J. Rollins; Astrid van Halteren
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Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung

Nature Communications
2019-09-03 | Journal article
Contributors: Joey Schyns; Qiang Bai; Cecilia Ruscitti; Coraline Radermecker; Sebastiaan De Schepper; Svetoslav Chakarov; Frédéric Farnir; Dimitri Pirottin; Florent Ginhoux; Guy Boeckxstaens et al.
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Biphasic impact of prenatal inflammation and macrophage depletion on the wiring of neocortical inhibitory circuits

2019-06-13 | Other
Contributors: Morgane Sonia Thion; Coralie-Anne Mosser; Isabelle Férézou; Pauline Grisel; Sofia Baptista; Donovan Low; Florent Ginhoux; Sonia Garel; Etienne Audinat
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A rule-based data-informed cellular consensus map of the human mononuclear phagocyte cell space

2019-06-03 | Other
Contributors: Patrick Günther; Branko Cirovic; Kevin Baßler; Kristian Händler; Matthias Becker; Charles Antoine Dutertre; Venetia Bigley; Evan Newell; Matthew Collin; Florent Ginhoux et al.
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Fat‐fated microglial dysfunction

The EMBO Journal
2019-01-15 | Journal article
Contributors: Aymeric Silvin; Florent Ginhoux
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The immunological anatomy of the skin

Nature Reviews Immunology
2019-01-14 | Journal article
Contributors: Kenji Kabashima; Tetsuya Honda; Florent Ginhoux; Gyohei Egawa
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Dimensionality reduction for visualizing single-cell data using UMAP

Nature Biotechnology
2019-01-03 | Journal article
Contributors: Etienne Becht; Leland McInnes; John Healy; Charles-Antoine Dutertre; Immanuel W H Kwok; Lai Guan Ng; Florent Ginhoux; Evan W Newell
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Embryonic macrophages and microglia ablation alter the development of dorsal root ganglion sensory neurons in mouse embryos

Glia
2018-11 | Journal article
Contributors: Monara Kaélle Sérvulo Cruz Angelim; Luciana Maria Silva de Seixas Maia; Christine Mouffle; Florent Ginhoux; Donovan Low; Angela Amancio‐Dos‐Santos; Jennifer Makhoul; Hervé Le Corronc; Jean‐Marie Mangin; Pascal Legendre
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Publisher Correction: Studying tissue macrophages in vitro: are iPSC-derived cells the answer?

Nature Reviews Immunology
2018-11-30 | Journal article
Contributors: Christopher Z. W. Lee; Tatsuya Kozaki; Florent Ginhoux
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Studying tissue macrophages in vitro: are iPSC-derived cells the answer?

Nature Reviews Immunology
2018-11-23 | Journal article
Contributors: Christopher Z. W. Lee; Tatsuya Kozaki; Florent Ginhoux
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Microglia and early brain development: An intimate journey

Science
2018-10-12 | Journal article
Contributors: Morgane S. Thion; Florent Ginhoux; Sonia Garel
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The mysterious origins of microglia

Nature Neuroscience
2018-07-25 | Journal article
Contributors: Florent Ginhoux; Sonia Garel
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Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

Nature Cell Biology
2018-07-18 | Journal article
Contributors: Amir Giladi; Franziska Paul; Yoni Herzog; Yaniv Lubling; Assaf Weiner; Ido Yofe; Diego Jaitin; Nina Cabezas-Wallscheid; Regine Dress; Florent Ginhoux et al.
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Life Science Alliance, from the Academic Editors

Life Science Alliance
2018-01 | Journal article
Contributors: Julia Promisel Cooper; Florent Ginhoux; Sebastian Jessberger; Michael Overholtzer
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Blood‐brain barrier development: Systems modeling and predictive toxicology

Birth Defects Research
2017-12 | Journal article
Contributors: Katerine S. Saili; Todd J. Zurlinden; Andrew J. Schwab; Aymeric Silvin; Nancy C. Baker; E. Sidney Hunter, III; Florent Ginhoux; Thomas B. Knudsen
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Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development

Nature Communications
2016-06-30 | Journal article
Contributors: Jinmiao Chen; Andreas Schlitzer; Svetoslav Chakarov; Florent Ginhoux; Michael Poidinger
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New insights into the multidimensional concept of macrophage ontogeny, activation and function

Nature Immunology
2016-01-17 | Journal article
Contributors: Florent Ginhoux; Joachim L Schultze; Peter J Murray; Jordi Ochando; Subhra K Biswas
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Peer review (74 reviews for 20 publications/grants)

Review activity for Cancer cell. (2)
Review activity for Cell reports. (1)
Review activity for Cell research (1)
Review activity for Cell. (2)
Review activity for Developmental cell. (1)
Review activity for Experimental hematology. (1)
Review activity for Immunity. (5)
Review activity for Journal of hepatology. (1)
Review activity for Nature (15)
Review activity for Nature biotechnology. (2)
Review activity for Nature cancer. (4)
Review activity for Nature communications (12)
Review activity for Nature immunology. (15)
Review activity for Nature medicine. (2)
Review activity for Nature metabolism. (1)
Review activity for Nature neuroscience. (5)
Review activity for Nature reviews. (1)
Review activity for Nature reviews. (1)
Review activity for Neuron. (1)
Review activity for Trends in cancer. (1)