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Scopus Author ID: 54982700600
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South Africa

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Employment (3)

University of KwaZulu-Natal: Durban, ZA

2021-10-01 to present | Senior Lecturer and Researcher (Biochemistry)
Employment
Source: Self-asserted source
Ofentse Jacob Pooe

University of KwaZulu-Natal: Durban, KwaZulu-Natal, ZA

2017-02-01 to 2021-09-30 | Lecturer (Biochemistry)
Employment
Source: Self-asserted source
Ofentse Jacob Pooe

Council for Scientific and Industrial Research: Pretoria, ZA

2014-12-01 to 2017-01-31 | Post-Doc Fellow (BioSciences)
Employment
Source: Self-asserted source
Ofentse Jacob Pooe

Education and qualifications (1)

University of Zululand: KwaDlangezwa, ZA

2011-02-01 to 2015-05-12 | PhD (Biochemistry and Microbiology)
Education
Source: Self-asserted source
Ofentse Jacob Pooe

Works (50 of 62)

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Page 1 of 2

A promising class of antiprotozoal agents, design and synthesis of novel Pyrimidine–Cinnamoyl hybrids

European Journal of Medicinal Chemistry
2025-01 | Journal article
DOI: 10.1016/j.ejmech.2024.116944
Part of ISSN: 0223-5234
Contributors: Francis Kayamba; Rajshekhar Karpoormath; Vincent A. Obakachi; Mavela Mahlalela; Danny Banda; Robyn L. van Zyl; Sahil Lala; Tawanda Zininga; Addmore Shonhai; Baji Baba Shaik et al.
Source: Self-asserted source
Ofentse Jacob Pooe via Crossref Metadata Search

Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies

BMC Chemistry
2025-01-18 | Journal article
DOI: 10.1186/s13065-025-01380-x
Part of ISSN: 2661-801X
Contributors: Lindiwe Khumbuzile Zuma; Ofentse Jacob Pooe; Nonduduzo Hlengiwe Mabaso; John Alake; Vincent A. Obakachi; Sinethemba Yakobi; Nothando Gasa; Rajshekhar Karpoormath; Mthokozisi Simelane
Source: Self-asserted source
Ofentse Jacob Pooe via Crossref Metadata Search

Establishment of novel receptor-antibody sandwich assays to broadly detect Bacillus thuringiensis Cry1 and Cry2 toxins

International Journal of Biological Macromolecules
2024 | Journal article
DOI: 10.1016/j.ijbiomac.2023.128034
EID:

2-s2.0-85177064505

Part of ISSN: 18790003 01418130
Contributors: Shen, C.; Meng, M.; Jin, J.; Hu, X.; Lin, M.; Gao, M.; Zhang, X.; Zhu, Q.; Xu, C.; Xie, Y. et al.
Source: Self-asserted source
Ofentse Jacob Pooe via Scopus - Elsevier

Molecular Docking and Structure-Activity Relationship Analysis of Target Compounds against Glyceraldehyde-3-Phosphate Dehydrogenase in Azithromycin-Resistant Neisseria gonorrhoeae

ChemistrySelect
2024 | Journal article
DOI: 10.1002/slct.202303341
EID:

2-s2.0-85186237374

Part of ISSN: 23656549
Contributors: Yakobi, S.; Zuma, L.; Pooe, O.
Source: Self-asserted source
Ofentse Jacob Pooe via Scopus - Elsevier

Ursolic acid acetate and iso-mukaadial acetate bind to Plasmodium falciparum Hsp90, abrogating its chaperone function in vitro

Naunyn-Schmiedeberg's Archives of Pharmacology
2024 | Journal article
DOI: 10.1007/s00210-024-02944-9
EID:

2-s2.0-85182836622

Part of ISSN: 14321912 00281298
Contributors: Nndwammbi, A.A.T.; Dongola, T.H.; Shonhai, A.; Mokoena, F.; Pooe, O.J.; Simelane, M.B.C.
Source: Self-asserted source
Ofentse Jacob Pooe via Scopus - Elsevier

Antiplasmodial potential of compounds isolated from Ziziphus mucronata and their binding to Plasmodium falciparum HGXPRT using biophysical and molecular docking studies

Naunyn-Schmiedeberg's Archives of Pharmacology
2024-11-19 | Journal article
DOI: 10.1007/s00210-024-03611-9
Part of ISSN: 1432-1912
Contributors: Kgaugelo J. Masia; Ndumiso N. Mhlongo; Ofentse J. Pooe; Mohammed A. Ibrahim; Abidemi P. Kappo; Mthokozisi B. C. Simelane
Source: Self-asserted source
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Rational design and application of broad-spectrum antibodies for Bt Cry toxins determination

Analytical Biochemistry
2024-10 | Journal article
DOI: 10.1016/j.ab.2024.115584
Part of ISSN: 0003-2697
Contributors: Jiafeng Jin; Wei Chen; Chongxin Xu; Ofentse Jacob Pooe; Yajing Xie; Cheng Shen; Meng Meng; Qin Zhu; Xiao Zhang; Xianjin Liu et al.
Source: Self-asserted source
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A molecular and phenotypic analysis of the prevalence and patterns of antimicrobial resistance in Neisseria gonorrhoeae isolates from Kwazulu Natal, South Africa

Scientific African
2024-09 | Journal article
DOI: 10.1016/j.sciaf.2024.e02334
Contributors: Sinethemba Hopewell Yakobi; Nothando Gasa; Ofentse Jacob Pooe
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Characterization of the individual domains of the Bacillus thuringiensis Cry2Aa implicates Domain I as a possible binding site to Helicoverpa armigera

Journal of Invertebrate Pathology
2024-07 | Journal article
DOI: 10.1016/j.jip.2024.108129
Part of ISSN: 0022-2011
Contributors: Meng Meng; Cheng Shen; Manman Lin; Jiafeng Jin; Wei Chen; Xiao Zhang; Chongxin Xu; Xiaodan Hu; Qing Zhu; Chengyu Chen et al.
Source: Self-asserted source
Ofentse Jacob Pooe via Crossref Metadata Search

Bioprospecting the liver protective activity of betulinic acid isolated from the stem bark of Ziziphus mucronata Willd. subsp. mucronata

Scientific African
2024-06 | Journal article
DOI: 10.1016/j.sciaf.2024.e02182
Contributors: Gideon Ayeni; Mthokozisi BC Simelane; Sinethemba Yakobi; Stanley Makumire; Ofentse Jacob Pooe
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A systematic review of Neisseria gonorrhoeae drug resistance development in South Africa

Brazilian Journal of Microbiology
2024-04-25 | Journal article
DOI: 10.1007/s42770-024-01281-6
Part of ISSN: 1678-4405
Contributors: Sinethemba H. Yakobi; Yolisa B. Magibile; Ofentse J. Pooe
Source: Self-asserted source
Ofentse Jacob Pooe via Crossref Metadata Search

An Exploratory Review of the Potential of Lytic Proteins and Bacteriophages for the Treatment of Tuberculosis

Microorganisms
2024-03-12 | Journal article
DOI: 10.3390/microorganisms12030570
Contributors: Sibongile Mtimka; Priyen Pillay; Lusisizwe Kwezi; Ofentse Jacob Pooe; Tsepo Lebiletsa Tsekoa
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Antimicrobial Potential of Organic Phenolic Compounds from Wild Mushroom Extracts: Impact on Proliferation and Kinetic Growth of Multidrug‐Resistant Neisseria gonorrhoeae Strains

Journal of Food Biochemistry
2024-01 | Journal article
DOI: 10.1155/2024/2336255
Contributors: Sinethemba Yakobi; Lindiwe Zuma; Nothando Gasa; Ofentse Pooe; Abd El-Latif Hesham
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Investigation into the Interaction between Penicillin‐Resistant and Penicillin‐Susceptible Gonococcal Penicillin‐Binding Protein 2 and Target Phenolic Ligands through Molecular Docking Studies and Structure‐Activity Relationship Analysis

Advances in Pharmacological and Pharmaceutical Sciences
2024-01 | Journal article
DOI: 10.1155/2024/2585922
Contributors: Sinethemba Yakobi; Lindiwe Zuma; Ofentse Pooe; Alamgir Ahmad Dar
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A Comprehensive Review of Some Heat-Shock Proteins in the Development and Progression of Human Breast Cancer

Drug and Therapy Development for Triple Negative Breast Cancer
2023 | Book chapter
Part of DOI: 10.1002/9783527841165.ch13
EID:

2-s2.0-85168488902

ISBN: 9783527841165 9783527351756
Contributors: Makhoba, X.H.; Pooe, O.J.
Source: Self-asserted source
Ofentse Jacob Pooe via Scopus - Elsevier

An Anti-Idiotypic Antibody Mimicking Bacillus Thuringiensis Cry2aa Toxin Broadly Binds to Recombinant Toxin-Bindingfragments Derived from Cadherin-Like Proteins of Plutellaxylostella and Helicoverpa Armigera

SSRN
2023 | Other
DOI: 10.2139/ssrn.4633023
EID:

2-s2.0-85177798923

Part of ISSN: 15565068
Contributors: Liu, Y.; Meng, M.; Shen, C.; Lin, M.; Chen, W.; Zhang, X.; Xu, C.; Hu, X.; Zhu, Q.; Chen, C. et al.
Source: Self-asserted source
Ofentse Jacob Pooe via Scopus - Elsevier

Computational Analysis, In silico Functional Annotation, and Expression of Recombinant PE_PGRS Protein Biomarkers Found in Mycobacterium tuberculosis

Open Bioinformatics Journal
2023 | Journal article
DOI: 10.2174/18750362-v16-e230306-2022-6
EID:

2-s2.0-85153722717

Part of ISSN: 18750362
Contributors: Moodley-Reddy, A.; Chiliza, T.E.; Pooe, O.J.
Source: Self-asserted source
Ofentse Jacob Pooe via Scopus - Elsevier

Iso-Mukaadial Acetate and Ursolic Acid Acetate Bind to Plasmodium Falciparum Heat Shock Protein 70: Towards Targeting Parasite Protein Folding Pathway

SSRN
2023 | Other
DOI: 10.2139/ssrn.4379600
EID:

2-s2.0-85150716161

Part of ISSN: 15565068
Contributors: Opoku, F.; Govender, P.P.; Pooe, O.J.; Dongola, T.H.; Shonhai, A.; Simelane, M.B.C.
Source: Self-asserted source
Ofentse Jacob Pooe via Scopus - Elsevier

The Influence of Organic Phenolic Compounds on the Proliferation and Kinetic Growth of Pathogenic Multi-Drug Resistant Neisseria Gonorrhoeae Strains

SSRN
2023 | Other
DOI: 10.2139/ssrn.4564377
EID:

2-s2.0-85171595626

Part of ISSN: 15565068
Contributors: Yakobi, S.; Zuma, L.; Gasa, N.; Pooe, O.
Source: Self-asserted source
Ofentse Jacob Pooe via Scopus - Elsevier

A Systematic Review of Curtisia dentata Endemic to South Africa: Phytochemistry, Pharmacology, and Toxicology

Life
2023-11-03 | Journal article
DOI: 10.3390/life13112159
Contributors: Maropeng Vellry Raletsena; Ofentse Jacob Pooe; Nkoana Ishmael Mongalo
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A Comprehensive Review of Some Heat‐Shock Proteins in the Development and Progression of Human Breast Cancer

Drug and Therapy Development for Triple Negative Breast Cancer
2023-10-23 | Book chapter
DOI: 10.1002/9783527841165.ch13
Part of ISBN: 9783527351756
Part of ISBN: 9783527841165
Contributors: Xolani H. Makhoba; Ofentse Jacob Pooe
Source: Self-asserted source
Ofentse Jacob Pooe

Evaluation of Antimicrobial Activity by Marine <em>Nocardiopsis dassonvillei </em>against Foodborne <em>Listeria monocytogenes</em> and Shiga Toxin-Producing <em>Escherichia coli</em>

2023-08-15 | Preprint
DOI: 10.20944/preprints202308.1075.v1
Contributors: Siyanda S. Ngema; Solomuzi H. Khumalo; Michael C. Ojo; Ofentse J. Pooe; Tsolanku Sidney Maliehe; Albertus K. Basson; Evelyn Madoroba
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South Africa's indigenous microbial diversity for industrial applications: A review of the current status and opportunities

Heliyon
2023-06 | Journal article
DOI: 10.1016/j.heliyon.2023.e16723
Contributors: Varsha Chhiba; Priyen Pillay; Sibongile Mtimka; Ghaneshree Moonsamy; Lusisizwe Kwezi; Ofentse J. Pooe; Tsepo L. Tsekoa
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In Vitro Antidiabetic, Antioxidant, and Cytotoxic Evaluation of Honeybush Tea (Cyclopia genistoides) Extracts

Journal of Food Biochemistry
2023-06-09 | Journal article
DOI: 10.1155/2023/8774094
Contributors: Nkosinathi D. Cele; Ntokozo E. Mthimunye; Qiniso B. Mkhwanazi; Seluleko Nxumalo; Freedom Tshabuse; Ofentse J. Pooe; Nireshni Chellan; Matthew S. Mthembu; Andy R. Opoku; Muhammed Yuceer
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Screening of Antimicrobial Properties and Bioactive Compounds of Pleurotus Ostreatus Extracts against Staphylococcus Aureus, Escherichia coli, and Neisseria Gonorrhoeae

Biochemistry Research International
2023-04-17 | Journal article
DOI: 10.1155/2023/1777039
Contributors: Sinethemba H. Yakobi; Senzosenkosi Mkhize; Ofentse J. Pooe; Saleh Ahmed Mohamed
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Identification of Emerging Multidrug-Resistant Neisseria gonorrhoeae Isolates against Five Major Antimicrobial Agent Options

Medical Sciences
2023-03-31 | Journal article
DOI: 10.3390/medsci11020028
Contributors: Sinethemba Hopewell Yakobi; Ofentse Jacob Pooe
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Bioprospecting the Biological Effects of Cultivating Pleurotus ostreatus Mushrooms from Selected Agro-Wastes and Maize Flour Supplements

Journal of Food Biochemistry
2023-03-29 | Journal article
DOI: 10.1155/2023/2762972
Contributors: Senzosenkosi Surprise Mkhize; Mthokozisi Blessing Cedric Simelane; Nkoana Ishmael Mongalo; Ofentse Jacob Pooe; N. A. DICA Maltar Strmečki
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Chemical Profile, Antioxidant and Antibacterial Activities, Mechanisms of Action of the Leaf Extract of Aloe arborescens Mill

Plants
2023-02-15 | Journal article
DOI: 10.3390/plants12040869
Contributors: Tsolanku Sidney Maliehe; Mduduzi Innocent Nqotheni; Jabulani Siyabonga Shandu; Tlou Nelson Selepe; Peter Masoko; Ofentse Jacob Pooe
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Computational Analysis, in silico Functional Annotation and Expression of Recombinant mycobacterium, PE_PGRS Protein Biomarkers

The Open Biology Journal
2023-01-12 | Journal article
DOI: 10.2174/18741967-v11-e230112-2022-6
Part of ISSN: 1874-1967
Contributors: Avanthi Moodley-Reddy; Thamsanqa Emmanuel Chiliza; Ofentse Jacob Pooe
Source: Self-asserted source
Ofentse Jacob Pooe via Crossref Metadata Search

Bioprospecting of endophytic actinobacterium associated with Aloe ferox mill for antibacterial activity

BMC Complementary Medicine and Therapies
2022 | Journal article
DOI: 10.1186/s12906-022-03733-8
EID:

2-s2.0-85139150290

Part of ISSN: 26627671
Contributors: Maliehe, T.S.; Mbambo, M.; Ngidi, L.S.; Shandu, J.S.E.; Pooe, O.J.; Masoko, P.; Selepe, T.N.
Source: Self-asserted source
Ofentse Jacob Pooe via Scopus - Elsevier

Improved sensitivity of the anti-microcystin-LR ELISA using phage-displayed alpha-type anti-idiotypic nanobody.

Analytical biochemistry
2022-12 | Journal article
DOI: 10.1016/j.ab.2022.115030
PMID: 36572217
Contributors: Liu S; Lin M; Hu X; Shen C; Zhang X; Xu C; Zhu Q; Xie Y; Lu H; Wang Y et al.
Source: Self-asserted source
Ofentse Jacob Pooe via Europe PubMed Central
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Reverse vaccinology approach to design a multi-epitope vaccine construct based on the Mycobacterium tuberculosis biomarker PE_PGRS17

Immunologic Research
2022-08 | Journal article
DOI: 10.1007/s12026-022-09284-x
Contributors: Avanthi Moodley; Abiodun Fatoba; Moses Okpeku; Thamsanqa Emmanuel Chiliza; Mthokozisi Blessing Cedric Simelane; Ofentse Jacob Pooe
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Characterization and Biological Evaluation of Zinc Oxide Nanoparticles Synthesized from Pleurotus ostreatus Mushroom

Applied Sciences
2022-08-26 | Journal article
DOI: 10.3390/app12178563
Contributors: Senzosenkosi Surprise Mkhize; Ofentse Jacob Pooe; Sandile Khoza; Ishmael Nkoana Mongalo; Rene Khan; Mthokozisi Blessing Cedric Simelane
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Generation of Human Domain Antibody Fragments as Potential Insecticidal Agents against <i>Helicoverpa armigera</i> by Cadherin-Based Screening

Journal of Agricultural and Food Chemistry
2022-08-09 | Journal article
DOI: 10.1021/acs.jafc.2c02000
Part of ISSN: 0021-8561
Contributors: Xiaodan Hu; Xiao Zhang; Yuan Liu; Meijing Gao; Manman Lin; Yajing Xie; Qing Zhu; Chongxin Xu; Xianjin Liu; Dalene Vosloo et al.
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Ofentse Jacob Pooe via Crossref Metadata Search
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Mushroom‐Derived Products as an Alternative Antimalarial Therapeutics: A Review

Drug Development for Malaria
2022-08-05 | Other
DOI: 10.1002/9783527830589.ch10
Contributors: Senzosenkosi S. Mkhize; Kgothatso E. Machaba; Mthokozisi B. C. Simelane; Ofentse J. Pooe
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Ofentse Jacob Pooe via Crossref Metadata Search
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Recombinant Expression, Purification and PEGylation of DNA Ligases

Protein & Peptide Letters
2022-06 | Journal article
DOI: 10.2174/0929866529666220426122432
Contributors: Lindiwe Khumbuzile Zuma; Nothando Lovedale Gasa; Xolani Mazibuko; Mthokozisi Blessing C. Simelane; Priyen Pillay; Lusisizwe Kwezi; Tsepo Tsekoa; Ofentse Jacob Pooe
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The Effect of Supplementing Mushroom Growing Substrates on the Bioactive Compounds, Antimicrobial Activity, and Antioxidant Activity of Pleurotus ostreatus

Biochemistry Research International
2022-06-27 | Journal article
DOI: 10.1155/2022/9436614
Contributors: Senzosenkosi Surprise Mkhize; Mthokozisi Blessing Cedric Simelane; Ishmael Nkoana Mongalo; Ofentse Jacob Pooe; Saleh Ahmed Mohamed
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The Hepatoprotective Role of Warburgia salutaris and Iso-Mukaadial Acetate on Carbon tetrachloride Intoxicated Rats Model

Current Bioactive Compounds
2022-05-16 | Journal article
DOI: 10.2174/1573407217666210816105252
Part of ISSN: 1573-4072
Source: Self-asserted source
Ofentse Jacob Pooe
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Antimicrobial Resistance of Neisseria gonorrhoeae in Sub-Saharan Populations

Bacteria
2022-05-03 | Journal article
DOI: 10.3390/bacteria1020009
Contributors: Sinethemba H. Yakobi; Ofentse J. Pooe
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Identification of single domain antibodies with insect cytotoxicity using phage-display antibody library screening and Plutella xylostella ATP-binding cassette transporter subfamily C member 2 (ABCC2) -based insect cell expression system

International Journal of Biological Macromolecules
2022-03 | Journal article
DOI: 10.1016/j.ijbiomac.2022.03.143
Part of ISSN: 0141-8130
Contributors: Qing Zhu; Xiaodan Hu; Yuan Liu; Yajing Xie; Chongxin Xu; Manman Lin; Ofentse Jacob Pooe; Jianfeng Zhong; Meijing Gao; Lina Lu et al.
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Protein PEGylation: Navigating Recombinant Protein Stability, Aggregation, and Bioactivity

BioMed Research International
2022-01 | Journal article
DOI: 10.1155/2022/8929715
Contributors: Lindiwe Khumbuzile Zuma; Nothando Lovedale Gasa; Xolani Henry Makhoba; Ofentse Jacob Pooe; Zhizhong Song
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Lactate Dehydrogenase and Malate Dehydrogenase: Potential antiparasitic targets for drug development studies

Bioorganic & Medicinal Chemistry
2021-10 | Journal article
DOI: 10.1016/j.bmc.2021.116458
Part of ISSN: 0968-0896
Source: Self-asserted source
Ofentse Jacob Pooe
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Evaluating the Antioxidant and Heavy Metal Content of Pleurotus ostreatus Mushrooms Cultivated using Sugar Cane Agro-Waste

Pharmacognosy Journal
2021-07-06 | Journal article
DOI: 10.5530/pj.2021.13.108
Part of ISSN: 0975-3575
Contributors: Senzosenkosi Surprise Mkhize; Mthokozisi Blessing Cedric Simelane; Nothando Lovedale Gasa; Ofentse Jacob Pooe
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Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors

European Journal of Medicinal Chemistry
2021-05 | Journal article
DOI: 10.1016/j.ejmech.2021.113330
Contributors: Francis Kayamba; Teboho Malimabe; Idowu Kehinde Ademola; Ofentse Jacob Pooe; Narva Deshwar Kushwaha; Mavela Mahlalela; Robyn L. van Zyl; Michelle Gordon; Pertunia T. Mudau; Tawanda Zininga et al.
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Iso-mukaadial acetate and ursolic acid acetate inhibit the chaperone activity of Plasmodium falciparum heat shock protein 70-1

Cell Stress and Chaperones
2021-05 | Journal article
DOI: 10.1007/s12192-021-01212-6
Part of ISSN: 1355-8145
Contributors: Nicolaas Salomane; Ofentse J. Pooe; Mthokozisi B. C. Simelane
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Ofentse Jacob Pooe via Crossref Metadata Search
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Oxidative testicular injury: effect of L-leucine on redox, cholinergic and purinergic dysfunctions, and dysregulated metabolic pathways.

Amino acids
2021-02-14 | Journal article
DOI: 10.1007/s00726-021-02954-4
PMID: 33586041
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Ofentse Jacob Pooe
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<p>Potential Impact of the Multi-Target Drug Approach in the Treatment of Some Complex Diseases</p>

Drug Design, Development and Therapy
2020-08 | Journal article
DOI: 10.2147/DDDT.S257494
Contributors: Xolani H Makhoba; Claudio Viegas Jr.; Rebamang A Mosa; Flávia PD Viegas; Ofentse J Pooe
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Plant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications

Scientific Reports
2020-04-10 | Journal article
DOI: 10.1038/s41598-020-63052-1
Contributors: Advaita Acarya Singh; Ofentse Pooe; Lusisizwe Kwezi; Therese Lotter-Stark; Stoyan H. Stoychev; Kabamba Alexandra; Isak Gerber; Jinal N. Bhiman; Juan Vorster; Michael Pauly et al.
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Biological Role of Chalcones in Medicinal Chemistry

Vector-Borne Diseases: Recent Developments in Epidemiology and Control [Working Title]
2020-03-04 | Book chapter
DOI: 10.5772/intechopen.91626
Source: Self-asserted source
Ofentse Jacob Pooe

Cytotoxic and antioxidant activities of selected South African medicinal plants

Pharmacognosy Journal
2019 | Journal article
DOI: 10.5530/PJ.2019.11.234
EID:

2-s2.0-85077313080

Part of ISSN: 09753575
Contributors: Ayeni, G.; Pooe, O.J.; Singh, M.; Nundkumar, N.; Simelane, M.B.C.
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Ofentse Jacob Pooe via Scopus - Elsevier
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Peer review (2 reviews for 2 publications/grants)

Review activity for Cell stress & chaperones. (1)
Review activity for Molecular biology reports. (1)
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