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Employment (3)

Henry M. Jackson Foundation: Bethesda, Maryland, US

2023-02-06 to present | Director of Translation Research (Global Infectious Diseases)
Employment
Source: Self-asserted source
Lydie Trautmann

VGTI/OHSU: Beaverton, US

2019-09-01 to 2023-02-03 | Associate Professor
Employment
Source: Self-asserted source
Lydie Trautmann

U.S. Military HIV Research Program: Silver Spring, MD, US

2015-06-01 to 2019-08-31 | Chief, Cellular Immunology Section
Employment
Source: Self-asserted source
Lydie Trautmann

Education and qualifications (1)

Universite Paris V: Paris, FR

1999-01 to 2003-12 | PhD
Education
Source: Self-asserted source
Lydie Trautmann

Funding (5)

Critical Role of Cytotoxic T Cells in HIV Neuropathogenesis

2016-09-01 to 2021-05-31 | Grant
National Institute of Mental Health (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.6375805
GRANT_NUMBER: R01MH106466
Source: Self-asserted source
Lydie Trautmann via DimensionsWizard

Purging the latent HIV reservoir at ART inititation: A new eradication strategy

2014-09-19 to 2017-08-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.3801436
GRANT_NUMBER: R21AI116233
Source: Self-asserted source
Lydie Trautmann via DimensionsWizard

Preservation of adaptive immunity leads to HIV control upon treatment cessation.

2014-01-01 to 2019-12-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.2459963
GRANT_NUMBER: R01AI108433
Source: Self-asserted source
Lydie Trautmann via DimensionsWizard

Controlling the Influenza A H1N1 pandemic strain infection: dynamics and mechanisms of innate and adaptive immune responses in a system biology approach

2009-10-01 to 2010-09-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7658624
GRANT_NUMBER:

08afb99ee1e3dbd9279784c4cbdc2a6f
Source: Self-asserted source
Lydie Trautmann via DimensionsWizard

Determination of the molecular mechanisms by which PD-1 induces CD8 dysfunction in HIV infection

2007-04-01 to 2009-06-30 | Grant
Canadian Institutes of Health Research (Ottawa, CA)
URL: https://app.dimensions.ai/details/grant/grant.7662874
GRANT_NUMBER:

3af512c5ebbd8588e0cc5b551d6d6d4b
Source: Self-asserted source
Lydie Trautmann via DimensionsWizard

Works (47)

Modeling HIV-1 latency using primary CD4+ T cells from HIV-1 infected ART suppressed individuals.

Journal of virology
2019-03 | Journal article
DOI: 10.1128/jvi.02248-18
PMID: 30918072
Contributors: Takata H; Kessing C; Sy A; Lima N; Sciumbata J; Mori L; Jones RB; Chomont N; Michael NL; Valente S et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities.

The Journal of infectious diseases
2018-09 | Journal article
DOI: 10.1093/infdis/jiy337
PMID: 29868826
Contributors: D'Antoni ML; Byron MM; Chan P; Sailasuta N; Sacdalan C; Sithinamsuwan P; Tipsuk S; Pinyakorn S; Kroon E; Slike BM et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection.

Nature medicine
2018-06 | Journal article
DOI: 10.1038/s41591-018-0026-6
PMID: 29892063
PMC: PMC6092240
Contributors: Colby DJ; Trautmann L; Pinyakorn S; Leyre L; Pagliuzza A; Kroon E; Rolland M; Takata H; Buranapraditkun S; Intasan J et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Lymphoid tissue fibrosis is associated with impaired vaccine responses.

The Journal of clinical investigation
2018-05 | Journal article
DOI: 10.1172/JCI97377
PMID: 29781814
PMC: PMC6025977
Contributors: Kityo C; Makamdop KN; Rothenberger M; Chipman JG; Hoskuldsson T; Beilman GJ; Grzywacz B; Mugyenyi P; Ssali F; Akondy RS et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Study on the persistence of Zika virus (ZIKV) in body fluids of patients with ZIKV infection in Brazil.

BMC infectious diseases
2018-01 | Journal article
DOI: 10.1186/s12879-018-2965-4
PMID: 29357841
PMC: PMC5778641
Contributors: Calvet GA; Kara EO; Giozza SP; Bôtto-Menezes CHA; Gaillard P; de Oliveira Franca RF; de Lacerda MVG; da Costa Castilho M; Brasil P; de Sequeira PC et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Wake me up before you go: a strategy to reduce the latent HIV reservoir.

AIDS (London, England)
2018-01 | Journal article
DOI: 10.1097/QAD.0000000000001695
PMID: 29135580
PMC: PMC5758429
Contributors: Chomont N; Okoye AA; Favre D; Trautmann L
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

In Vivo Suppression of HIV Rebound by Didehydro-Cortistatin A, a "Block-and-Lock" Strategy for HIV-1 Treatment.

Cell reports
2017-10 | Journal article
DOI: 10.1016/j.celrep.2017.09.080
PMID: 29045830
PMC: PMC5653276
Contributors: Kessing CF; Nixon CC; Li C; Tsai P; Takata H; Mousseau G; Ho PT; Honeycutt JB; Fallahi M; Trautmann L et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

T Cell Immunity and Zika Virus Vaccine Development.

Trends in immunology
2017-06 | Journal article
DOI: 10.1016/j.it.2017.05.004
PMID: 28579320
Contributors: Lima NS; Rolland M; Modjarrad K; Trautmann L
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection.

Journal of acquired immune deficiency syndromes (1999)
2017-05 | Journal article
DOI: 10.1097/QAI.0000000000001301
PMID: 28177966
PMC: PMC5388590
Contributors: Kessing CF; Spudich S; Valcour V; Cartwright P; Chalermchai T; Fletcher JL; Takata H; Nichols C; Josey BJ; Slike B et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Delayed differentiation of potent effector CD8+ T cells reducing viremia and reservoir seeding in acute HIV infection.

Science translational medicine
2017-02 | Journal article
DOI: 10.1126/scitranslmed.aag1809
PMID: 28202771
PMC: PMC5678930
Contributors: Takata H; Buranapraditkun S; Kessing C; Fletcher JL; Muir R; Tardif V; Cartwright P; Vandergeeten C; Bakeman W; Nichols CN et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection.

PLoS pathogens
2016-07 | Journal article
DOI: 10.1371/journal.ppat.1005777
PMID: 27463374
PMC: PMC4963136
Contributors: Muir R; Metcalf T; Tardif V; Takata H; Phanuphak N; Kroon E; Colby DJ; Trichavaroj R; Valcour V; Robb ML et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Kill: boosting HIV-specific immune responses.

Current opinion in HIV and AIDS
2016-07 | Journal article
DOI: 10.1097/COH.0000000000000286
PMID: 27054280
PMC: PMC5098478
Contributors: Trautmann L
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Dengue Virus Antibodies Enhance Zika Virus Infection

2016-04 | Other
DOI: 10.1101/050112
OTHER-ID:

PPR26705
Contributors: Paul LM; Carlin ER; Jenkins MM; Tan AL; Barcellona CM; Nicholson CO; Trautmann L; Michael SF; Isern S
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection.

Journal of immunology (Baltimore, Md. : 1950)
2015-11 | Journal article
DOI: 10.4049/jimmunol.1501524
PMID: 26546609
PMC: PMC4670798
Contributors: Cubas R; van Grevenynghe J; Wills S; Kardava L; Santich BH; Buckner CM; Muir R; Tardif V; Nichols C; Procopio F et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Enhanced Influenza Virus-Like Particle Vaccination with a Structurally Optimized RIG-I Agonist as Adjuvant.

Journal of virology
2015-08 | Journal article
DOI: 10.1128/JVI.01526-15
PMID: 26269188
PMC: PMC4580177
Contributors: Beljanski V; Chiang C; Kirchenbaum GA; Olagnier D; Bloom CE; Wong T; Haddad EK; Trautmann L; Ross TM; Hiscott J
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

The Tat Inhibitor Didehydro-Cortistatin A Prevents HIV-1 Reactivation from Latency.

mBio
2015-07 | Journal article
DOI: 10.1128/mBio.00465-15
PMID: 26152583
PMC: PMC4495168
Contributors: Mousseau G; Kessing CF; Fromentin R; Trautmann L; Chomont N; Valente ST
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists.

Journal of virology
2015-05 | Journal article
DOI: 10.1128/JVI.00845-15
PMID: 26018150
PMC: PMC4505665
Contributors: Chiang C; Beljanski V; Yin K; Olagnier D; Ben Yebdri F; Steel C; Goulet ML; DeFilippis VR; Streblow DN; Haddad EK et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

SRSF1 RNA Recognition Motifs Are Strong Inhibitors of HIV-1 Replication.

Journal of virology
2015-04 | Journal article
DOI: 10.1128/JVI.00693-15
PMID: 25855733
PMC: PMC4474321
Contributors: Paz S; Lu ML; Takata H; Trautmann L; Caputi M
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Immune activation alters cellular and humoral responses to yellow fever 17Dvaccine.

The Journal of clinical investigation
2014-10 | Journal article
DOI: 10.1172/JCI77956
PMC: PMC4191000
Contributors: Muyanja E; Ssemaganda A; Ngauv P; Cubas R; Perrin H; Srinivasan D; Canderan G; Lawson B; Kopycinski J; Graham AS et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Immune activation alters cellular and humoral responses to yellow fever 17D vaccine.

The Journal of clinical investigation
2014-06 | Journal article
DOI: 10.1172/JCI75429
PMID: 24911151
PMC: PMC4071376
Contributors: Muyanja E; Ssemaganda A; Ngauv P; Cubas R; Perrin H; Srinivasan D; Canderan G; Lawson B; Kopycinski J; Graham AS et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Cell-based flow cytometry assay to measure cytotoxic activity.

Journal of visualized experiments : JoVE
2013-12 | Journal article
DOI: 10.3791/51105
PMID: 24378436
PMC: PMC4111270
Contributors: Noto A; Ngauv P; Trautmann L
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Developing Combined HIV Vaccine Strategies for a Functional Cure.

Vaccines
2013-10 | Journal article
DOI: 10.3390/vaccines1040481
PMID: 26344343
PMC: PMC4494210
Contributors: Noto A; Trautmann L
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Identification of a vibration regime favorable for bone healing and muscle in estrogen-deficient rats.

Calcified tissue international
2013-02 | Journal article
DOI: 10.1007/s00223-013-9706-x
PMID: 23416966
PMC: PMC3654182
Contributors: Komrakova M; Sehmisch S; Tezval M; Ammon J; Lieberwirth P; Sauerhoff C; Trautmann L; Wicke M; Dullin C; Stuermer KM et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Beyond surface markers with a universal cell secretion assay.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
2012-09 | Journal article
DOI: 10.1002/cyto.a.22200
PMID: 22997009
Contributors: Trautmann L
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection.

Blood
2012-09 | Journal article
DOI: 10.1182/blood-2012-04-422550
PMID: 22955926
PMC: PMC3743465
Contributors: Trautmann L; Mbitikon-Kobo FM; Goulet JP; Peretz Y; Shi Y; Van Grevenynghe J; Procopio FA; Boulassel MR; Routy JP; Chomont N et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Foxo3a: an integrator of immune dysfunction during HIV infection.

Cytokine & growth factor reviews
2012-06 | Journal article
DOI: 10.1016/j.cytogfr.2012.05.008
PMID: 22748238
PMC: PMC3418405
Contributors: van Grevenynghe J; Cubas RA; DaFonseca S; Metcalf T; Tremblay CL; Trautmann L; Sekaly RP; Schatzle J; Haddad EK
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation.

Journal of immunology (Baltimore, Md. : 1950)
2011-12 | Journal article
DOI: 10.4049/jimmunol.1102610
PMID: 22210916
PMC: PMC3262882
Contributors: Janbazian L; Price DA; Canderan G; Filali-Mouhim A; Asher TE; Ambrozak DR; Scheinberg P; Boulassel MR; Routy JP; Koup RA et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells.

Journal of immunological methods
2011-10 | Journal article
DOI: 10.1016/j.jim.2011.09.008
PMID: 21996428
Contributors: Mbitikon-Kobo FM; Bonneville M; Sekaly RP; Trautmann L
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Solving vaccine mysteries: a systems biology perspective.

Nature immunology
2011-07 | Journal article
DOI: 10.1038/ni.2078
PMID: 21772284
Contributors: Trautmann L; Sekaly RP
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

New approaches to design HIV-1 T-cell vaccines.

Current opinion in HIV and AIDS
2010-09 | Journal article
DOI: 10.1097/COH.0b013e32833d2cc0
PMID: 20978376
PMC: PMC2972542
Contributors: Perrin H; Canderan G; Sékaly RP; Trautmann L
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection.

Nature medicine
2010-03 | Journal article
DOI: 10.1038/nm.2106
PMID: 20208540
PMC: PMC4229134
Contributors: Said EA; Dupuy FP; Trautmann L; Zhang Y; Shi Y; El-Far M; Hill BJ; Noto A; Ancuta P; Peretz Y et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.

Nature medicine
2009-06 | Journal article
DOI: 10.1038/nm.1972
PMID: 19543283
PMC: PMC2859814
Contributors: Chomont N; El-Far M; Ancuta P; Trautmann L; Procopio FA; Yassine-Diab B; Boucher G; Boulassel MR; Ghattas G; Brenchley JM et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Harmonization guidelines for HLA-peptide multimer assays derived from results of a large scale international proficiency panel of the Cancer Vaccine Consortium.

Cancer immunology, immunotherapy : CII
2009-03 | Journal article
DOI: 10.1007/s00262-009-0681-z
PMID: 19259668
PMC: PMC2714899
Contributors: Britten CM; Janetzki S; Ben-Porat L; Clay TM; Kalos M; Maecker H; Odunsi K; Pride M; Old L; Hoos A et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Early interferon therapy for hepatitis C virus infection rescues polyfunctional, long-lived CD8+ memory T cells.

Journal of virology
2008-07 | Journal article
DOI: 10.1128/JVI.01083-08
PMID: 18667516
PMC: PMC2566289
Contributors: Badr G; Bédard N; Abdel-Hakeem MS; Trautmann L; Willems B; Villeneuve JP; Haddad EK; Sékaly RP; Bruneau J; Shoukry NH
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.

Nature medicine
2008-03 | Journal article
DOI: 10.1038/nm1728
PMID: 18311149
Contributors: van Grevenynghe J; Procopio FA; He Z; Chomont N; Riou C; Zhang Y; Gimmig S; Boucher G; Wilkinson P; Shi Y et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

T-cell exhaustion in HIV infection.

Current HIV/AIDS reports
2008-02 | Journal article
DOI: 10.1007/s11904-008-0003-7
PMID: 18417030
Contributors: El-Far M; Halwani R; Said E; Trautmann L; Doroudchi M; Janbazian L; Fonseca S; van Grevenynghe J; Yassine-Diab B; Sékaly RP et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Programmed death 1: a critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections.

Current opinion in HIV and AIDS
2007-05 | Journal article
DOI: 10.1097/coh.0b013e3280ebb5c9
PMID: 19372890
Contributors: Trautmann L; Said EA; Halwani R; Janbazian L; Chomont N; El-Far M; Breton G; Haddad EK; Sekaly RP
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Drug resistance mutations and the cellular immune response: a valuable synergy for the development of novel immune therapies.

Current opinion in HIV and AIDS
2007-03 | Journal article
DOI: 10.1097/coh.0b013e3280287a4d
PMID: 19372876
Contributors: Chomont N; Trautmann L; Routy JP; Sékaly RP
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

[Inhibition of the PD-1 pathway restores the effector function of HIV-specific T cells].

Medecine sciences : M/S
2007-01 | Journal article
DOI: 10.1051/medsci/200723124
PMID: 17212925
Contributors: Trautmann L; Chomont N; Sékaly RP
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells.

Journal of immunology (Baltimore, Md. : 1950)
2007-01 | Journal article
DOI: 10.4049/jimmunol.178.2.788
PMID: 17202340
Contributors: Younes SA; Trautmann L; Yassine-Diab B; Kalfayan LH; Kernaleguen AE; Cameron TO; Boulassel R; Stern LJ; Routy JP; Grossman Z et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction.

Nature medicine
2006-08 | Journal article
DOI: 10.1038/nm1482
PMID: 16917489
Contributors: Trautmann L; Janbazian L; Chomont N; Said EA; Gimmig S; Bessette B; Boulassel MR; Delwart E; Sepulveda H; Balderas RS et al.
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Selection of T cell clones expressing high-affinity public TCRs within Human cytomegalovirus-specific CD8 T cell responses.

Journal of immunology (Baltimore, Md. : 1950)
2005-11 | Journal article
DOI: 10.4049/jimmunol.175.9.6123
PMID: 16237109
Contributors: Trautmann L; Rimbert M; Echasserieau K; Saulquin X; Neveu B; Dechanet J; Cerundolo V; Bonneville M
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Simulations of string vibrations with boundary conditions of third kind using the functional transformation method.

The Journal of the Acoustical Society of America
2005-09 | Journal article
DOI: 10.1121/1.1992649
PMID: 16240834
Contributors: Trautmann L; Petrausch S; Bauer M
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Direct killing of Epstein-Barr virus (EBV)-infected B cells by CD4 T cells directed against the EBV lytic protein BHRF1.

Blood
2003-10 | Journal article
DOI: 10.1182/blood-2003-03-0930
PMID: 14563644
Contributors: Landais E; Saulquin X; Scotet E; Trautmann L; Peyrat MA; Yates JL; Kwok WW; Bonneville M; Houssaint E
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Dominant TCR V alpha usage by virus and tumor-reactive T cells with wide affinity ranges for their specific antigens.

European journal of immunology
2002-11 | Journal article
DOI: 10.1002/1521-4141(200211)32:11<3181::aid-immu3181>3.0.co;2-2
PMID: 12555663
Contributors: Trautmann L; Labarrière N; Jotereau F; Karanikas V; Gervois N; Connerotte T; Coulie P; Bonneville M
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

+1 Frameshifting as a novel mechanism to generate a cryptic cytotoxic T lymphocyte epitope derived from human interleukin 10.

The Journal of experimental medicine
2002-02 | Journal article
DOI: 10.1084/jem.20011399
PMID: 11828010
PMC: PMC2193594
Contributors: Saulquin X; Scotet E; Trautmann L; Peyrat MA; Halary F; Bonneville M; Houssaint E
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Frequent contribution of T cell clonotypes with public TCR features to the chronic response against a dominant EBV-derived epitope: application to direct detection of their molecular imprint on the human peripheral T cell repertoire.

Journal of immunology (Baltimore, Md. : 1950)
2000-08 | Journal article
DOI: 10.4049/jimmunol.165.4.2001
PMID: 10925283
Contributors: Lim A; Trautmann L; Peyrat MA; Couedel C; Davodeau F; Romagné F; Kourilsky P; Bonneville M
Source: Self-asserted source
Lydie Trautmann via Europe PubMed Central

Peer review (3 reviews for 2 publications/grants)

Review activity for EBioMedicine. (2)
Review activity for Nature communications (1)
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