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Funding (2)

Development of an in silico affinity maturation platform for therapeutic monoclonal antibodies

2024-03 to 2025-02 | Grant
Medical Research Council (Liverpool, GB)
Source: Self-asserted source
Alissa M Hummer

Machine Learning Approaches for In silico Optimisation and Design of Therapeutic Antibodies

2020-10-01 to 2024-03-31 | Grant
Medical Research Council (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.9470473
GRANT_NUMBER: 2445727
Source: Self-asserted source
Alissa M Hummer via DimensionsWizard

Works (10)

PLAbDab-nano: a database of camelid and shark nanobodies from patents and literature

Nucleic Acids Research
2025-01-06 | Journal article
DOI: 10.1093/nar/gkae881
Contributors: Gemma L Gordon; Alexander Greenshields-Watson; Parth Agarwal; Ashley Wong; Fergus Boyles; Alissa Hummer; Ana G Lujan Hernandez; Charlotte M Deane
Source: check_circle
Crossref

PLAbDab-nano: a database of camelid and shark nanobodies from patents and literature

2024-07-23 | Preprint
DOI: 10.1101/2024.07.19.604232
Contributors: Gemma L. Gordon; Alexander Greenshields-Watson; Parth Agarwal; Ashley Wong; Fergus Boyles; Alissa Hummer; Ana G. Lujan Hernandez; Charlotte M. Deane
Source: check_circle
Crossref

AntiFold: Improved antibody structure-based design using inverse folding

arXiv
2024-05-06 | Preprint
DOI: 10.48550/ARXIV.2405.03370
Contributors: Magnus Haraldson Høie; Alissa Hummer; Tobias H. Olsen; Broncio Aguilar-Sanjuan; Morten Nielsen; Charlotte M. Deane; Alissa M Hummer
Source: Self-asserted source
Alissa M Hummer

Baselining the Buzz Trastuzumab-HER2 Affinity, and Beyond

2024-03-29 | Preprint
DOI: 10.1101/2024.03.26.586756
Contributors: Lewis Chinery; Alissa M. Hummer; Brij Bhushan Mehta; Rahmad Akbar; Puneet Rawat; Andrei Slabodkin; Khang Le Quy; Fridtjof Lund-Johansen; Victor Greiff; Jeliazko R. Jeliazkov et al.
Source: check_circle
Crossref

Designing stable humanized antibodies

Nature Biomedical Engineering
2023-12-27 | Journal article
DOI: 10.1038/s41551-023-01168-1
Contributors: Alissa M. Hummer; Charlotte M. Deane
Source: check_circle
Crossref

Investigating the Volume and Diversity of Data Needed for Generalizable Antibody-Antigen ∆∆G Prediction

2023-05-19 | Preprint
DOI: 10.1101/2023.05.17.541222
Contributors: Alissa M. Hummer; Constantin Schneider; Lewis Chinery; Charlotte M. Deane
Source: check_circle
Crossref

Advances in computational structure-based antibody design

Current Opinion in Structural Biology
2022-06 | Journal article
DOI: 10.1016/j.sbi.2022.102379
Contributors: Alissa M. Hummer; Brennan Abanades; Charlotte M. Deane
Source: check_circle
Crossref

Humanization of antibodies using a machine learning approach on large-scale repertoire data

Bioinformatics
2021-11-18 | Journal article
DOI: 10.1093/bioinformatics/btab434
Contributors: Claire Marks; Alissa M Hummer; Mark Chin; Charlotte M Deane; Pier Luigi Martelli
Source: check_circle
Crossref

Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice.

Gastroenterology
2020-02-12 | Journal article
DOI: 10.1053/j.gastro.2020.02.011
PMID: 32060001
Source: Self-asserted source
Alissa M Hummer

A Mass-Spectrometry-Based Approach to Distinguish Annular and Specific Lipid Binding to Membrane Proteins.

Angewandte Chemie (International ed. in English)
2020-01-29 | Journal article
DOI: 10.1002/anie.201914411
PMID: 31886601
PMC: PMC7065234
Source: Self-asserted source
Alissa M Hummer

Peer review (3 reviews for 2 publications/grants)

Review activity for Nature communications (2)
Review activity for PLoS computational biology. (1)
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