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Scopus Author ID: 8579719700

Keywords

Protein folding, aggregation, amyloid fibril, modeling and dynamic simulation

Countries

India

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Employment (2)

University of Hyderabad: Hyderabad, Telangana, IN

2021-04-08 to present | Associate Professor (Department of Biotechnology & Bioinformatics, School of Life sciences)
Employment
Source: Self-asserted source
N. Prakash Prabhu

University of Hyderabad: Hyderabad, Telangana, IN

2009-04-08 to 2021-04-07 | Assistant Professor (Department of Biotechnology & Bioinformatics, School of Life sciences)
Employment
Source: Self-asserted source
N. Prakash Prabhu

Education and qualifications (3)

University of Hyderabad: India, Telangana, IN

2002-07 to 2008-05 | PhD (School of Chemistry)
Education
Source: Self-asserted source
N. Prakash Prabhu

Thiagarajar College: Madurai, Tamil Nadu, IN

2000-07-01 to 2002-05-31 | MSc (Department of Chemistry)
Education
Source: Self-asserted source
N. Prakash Prabhu

Thiagarajar College: Madurai, Tamil Nadu, IN

1997-01-07 to 2000-05-31 | BSc (Department of Chemistry)
Education
Source: Self-asserted source
N. Prakash Prabhu

Works (44)

Stability and Fibrillation of Lysozyme in the Mixtures of Ionic Liquids with Varying Hydrophobicity

ChemPhysChem
2025-03-15 | Journal article
DOI: 10.1002/cphc.202400743
Contributors: Pratibha Kushwaha; Abhinav Hatwar; N. Prakash Prabhu
Source: check_circle
Crossref

Correction to “Uncovering Hydroxynitrile Lyase Variants with Promiscuous Diastereoselective Nitroaldolase Activity toward the Highly Stereocontrolled Synthesis of Anti β-Nitroalcohols”

ACS Catalysis
2024-12-20 | Journal article
DOI: 10.1021/acscatal.4c06888
Contributors: Ayon Chaterjee; G. Priyanka; N. Prakash Prabhu; Santosh Kumar Padhi
Source: check_circle
Crossref

Uncovering Hydroxynitrile Lyase Variants with Promiscuous Diastereoselective Nitroaldolase Activity toward the Highly Stereocontrolled Synthesis of Anti β-Nitroalcohols

ACS Catalysis
2024-08-16 | Journal article
DOI: 10.1021/acscatal.4c04000
Contributors: Ayon Chatterjee; G. Priyanka; N. Prakash Prabhu; Santosh Kumar Padhi
Source: check_circle
Crossref

Aromatic vs alicyclic: Hydrophobicity of the ionic liquid on protein stability and fibril formation

Journal of Molecular Liquids
2024-02 | Journal article
DOI: 10.1016/j.molliq.2023.123920
Contributors: Pratibha Kushwaha; N. Prakash Prabhu
Source: check_circle
Crossref

Synergistic Effect of Charged Amino Acids on the Stability and Fibril Formation of Lysozyme

ChemistrySelect
2023-11-06 | Journal article
DOI: 10.1002/slct.202302409
Contributors: Subhasree Ghosh; N. Prakash Prabhu
Source: check_circle
Crossref

Imidazolium-based ionic liquids with increasing alkyl chain length of cations decrease the stability and fibrillation propensity of lysozyme

New Journal of Chemistry
2022 | Journal article
DOI: 10.1039/D2NJ00559J
Contributors: Pratibha Kushwaha; N. Prakash Prabhu
Source: check_circle
Crossref

Polyols, increasing global stability of cytochrome c, destabilize the thermal unfolding intermediate

Journal of Biomolecular Structure and Dynamics
2022-12-05 | Journal article
DOI: 10.1080/07391102.2021.1956593
Contributors: K. Tejaswi Naidu; N. Prakash Prabhu
Source: check_circle
Crossref

An able-cryoprotectant and a moderate denaturant: distinctive character of ethylene glycol on protein stability

Journal of Biomolecular Structure and Dynamics
2022-01-22 | Journal article
DOI: 10.1080/07391102.2020.1819422
Contributors: K. Tejaswi Naidu; N. Prakash Prabhu
Source: check_circle
Crossref

Cryo vs Thermo: Duality of Ethylene Glycol on the Stability of Proteins

The Journal of Physical Chemistry B
2020-11-12 | Journal article
DOI: 10.1021/acs.jpcb.0c06247
Contributors: K. Tejaswi Naidu; D. Krishna Rao; N. Prakash Prabhu
Source: check_circle
Crossref

Spontaneous lid closure and substrate-induced lid opening dynamics of human pancreatic lipase-related protein 2: A computational study

Journal of Molecular Structure
2020-10 | Journal article
DOI: 10.1016/j.molstruc.2020.128365
Part of ISSN: 0022-2860
Source: Self-asserted source
N. Prakash Prabhu

Surface hydration and preferential interaction directs the charged amino acids-induced changes in protein stability

Journal of Molecular Graphics and Modelling
2020-07 | Journal article
DOI: 10.1016/j.jmgm.2020.107602
Part of ISSN: 1093-3263
Source: Self-asserted source
N. Prakash Prabhu

Chain Compaction and Synergistic Destabilization of Globular Proteins by Mixture of Denaturants

ChemistrySelect
2019-12-19 | Journal article
DOI: 10.1002/slct.201903122
Contributors: Bramhini Anumalla; N. Prakash Prabhu
Source: check_circle
Crossref

Counteracting Effect of Charged Amino Acids Against the Destabilization of Proteins by Arginine

Applied Biochemistry and Biotechnology
2019-10-06 | Journal article
DOI: 10.1007/s12010-019-03026-w
Contributors: Bramhini Anumalla; N. Prakash Prabhu
Source: check_circle
Crossref

A putative merR family transcription factor Slr0701 regulates mercury inducible expression of MerA in the cyanobacterium Synechocystis sp. PCC6803

MicrobiologyOpen
2019-09 | Journal article
DOI: 10.1002/mbo3.838
Part of ISSN: 2045-8827
Part of ISSN: 2045-8827
Source: Self-asserted source
N. Prakash Prabhu

Med PS erver: A database for identification of therapeutic targets and novel leads pertaining to natural products

Chemical Biology & Drug Design
2019-04 | Journal article
DOI: 10.1111/cbdd.13430
Part of ISSN: 1747-0277
Part of ISSN: 1747-0285
Source: Self-asserted source
N. Prakash Prabhu

Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme by Withaferin-A

BMC Research Notes
2018 | Journal article
DOI: 10.1186/s13104-018-3354-1
Source: Self-asserted source
N. Prakash Prabhu

Binding orientation and interaction of bile salt in its ternary complex with pancreatic lipase-colipase system

Biochemical and Biophysical Research Communications
2018-05 | Journal article
DOI: 10.1016/j.bbrc.2018.04.018
Contributors: Neshatul Haque; N. Prakash Prabhu
Source: check_circle
Crossref

Glutamate Induced Thermal Equilibrium Intermediate and Counteracting Effect on Chemical Denaturation of Proteins

The Journal of Physical Chemistry B
2018-01-25 | Journal article
DOI: 10.1021/acs.jpcb.7b10561
Contributors: Bramhini Anumalla; N. Prakash Prabhu
Source: check_circle
Crossref

Analysing the microenvironment of 2-p-toluidinylnaphthalene-6-sulfonate (TNS) in solvents and in different conformational states of proteins in relation to its fluorescence properties: a computational study

Physical Chemistry Chemical Physics
2017 | Journal article
DOI: 10.1039/C7CP03951D
Contributors: Neshatul Haque; Krishnakanth Baratam; N. Prakash Prabhu
Source: check_circle
Crossref

Structural studies of aminopeptidase P from Plasmodium falciparum: A novel target against malaria

Letters in Drug Design and Discovery
2017 | Journal article
DOI: 10.2174/1570180813666160725113524
EID:

2-s2.0-85011829423
Contributors: Snigdha, P.; Rao, P.L.; Prabhu, N.P.; Qureshi, I.A.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Concentration dependent switch in the kinetic pathway of lysozyme fibrillation: Spectroscopic and microscopic analysis

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
2017-08 | Journal article
DOI: 10.1016/j.saa.2017.04.011
Contributors: E. Kiran Kumar; Deepak Kumar Prasad; N. Prakash Prabhu
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Kinetics of protein fibril formation: Methods and mechanisms

International Journal of Biological Macromolecules
2017-07 | Journal article
DOI: 10.1016/j.ijbiomac.2016.06.052
Contributors: E. Kiran Kumar; Neshatul Haque; N. Prakash Prabhu
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

In silico screening for identification of novel β-1,3-glucan synthase inhibitors using pharmacophore and 3D-QSAR methodologies

SpringerPlus
2016 | Journal article
DOI: 10.1186/s40064-016-2589-3
EID:

2-s2.0-84983058644
Contributors: Meetei, P.A.; Rathore, R.S.; Prabhu, N.P.; Vindal, V.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

In silico Structural characterization of podocin and assessment of nephrotic syndrome-associated podocin mutants

IUBMB Life
2016 | Journal article
DOI: 10.1002/iub.1515
EID:

2-s2.0-84975270119
Contributors: Mulukala, S.K.N.; Nishad, R.; Kolligundla, L.P.; Saleem, M.A.; Prabhu, N.P.; Pasupulati, A.K.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Lid closure dynamics of porcine pancreatic lipase in aqueous solution

Biochimica et Biophysica Acta - General Subjects
2016 | Journal article
DOI: 10.1016/j.bbagen.2016.05.004
EID:

2-s2.0-84970024738
Contributors: Haque, N.; Prabhu, N.P.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Lid dynamics of porcine pancreatic lipase in non-aqueous solvents

Biochimica et Biophysica Acta - General Subjects
2016 | Journal article
DOI: 10.1016/j.bbagen.2016.05.006
EID:

2-s2.0-84969962439
Contributors: Haque, N.; Prabhu, N.P.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Modeling of babesipain-1 and identification of natural and synthetic leads for bovine babesiosis drug development

Journal of Molecular Modeling
2016 | Journal article
DOI: 10.1007/s00894-016-2945-9
EID:

2-s2.0-84961225936
Contributors: Meetei, P.A.; Rathore, R.S.; Prabhu, N.P.; Vindal, V.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Sodium dodecyl sulphate (SDS) induced changes in propensity and kinetics of α-lactalbumin fibrillation

International Journal of Biological Macromolecules
2015-11-01 | Journal article
DOI: 10.1016/j.ijbiomac.2015.09.007
Contributors: E. Kiran Kumar; Shamsul Qumar; N. Prakash Prabhu
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

3D modeling of dengue virus NS4B and Chikungunya virus nsP4: Identification of a common drug target and designing a single antiviral inhibitor

Current Computer-Aided Drug Design
2014 | Journal article
EID:

2-s2.0-84946899894
Contributors: Satheesh, G.; Prabhu, N.P.; Venkataramana, M.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Differential effects of ionic and non-ionic surfactants on lysozyme fibrillation

Physical Chemistry Chemical Physics
2014 | Journal article
DOI: 10.1039/c4cp02423k
EID:

2-s2.0-84907967280
Contributors: Kumar, E.K.; Prabhu, N.P.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Insights into protein-TNS (2-p-toluidinylnaphthalene-6-sulfonate) interaction using molecular dynamics simulation

Journal of Molecular Structure
2014 | Journal article
DOI: 10.1016/j.molstruc.2014.04.040
EID:

2-s2.0-84901197360
Contributors: Haque, N.; Prabhu, N.P.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking

Medicinal Chemistry Research
2014 | Journal article
DOI: 10.1007/s00044-014-0950-z
EID:

2-s2.0-84904445302
Contributors: Meetei, P.A.; Hauser, A.S.; Raju, P.S.; Rathore, R.S.; Prabhu, N.P.; Vindal, V.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Off-pathway intermediate(s) in the refolding of alkaline ferrocytochrome c: A pulse-labeling HX NMR study

Nuclear Magnetic Resonance (NMR): Theory, Applications and Technology
2014 | Book
EID:

2-s2.0-84949489948
Contributors: Rao, D.K.; Prabhu, N.P.; Bhuyan, A.K.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Stability and Activity of Porcine Lipase Against Temperature and Chemical Denaturants

Applied Biochemistry and Biotechnology
2014 | Journal article
DOI: 10.1007/s12010-014-1220-8
EID:

2-s2.0-84911887644
Contributors: Chaitanya, P.K.; Prabhu, N.P.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

CyanoPhyChe: A Database for Physico-Chemical Properties, Structure and Biochemical Pathway Information of Cyanobacterial Proteins

PLoS ONE
2012 | Journal article
DOI: 10.1371/journal.pone.0049425
EID:

2-s2.0-84869745035
Contributors: Arun, P.V.P.S.; Bakku, R.K.; Subhashini, M.; Singh, P.; Prabhu, N.P.; Suzuki, I.; Prakash, J.S.S.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

NeMedPlant: a database of therapeutic applications and chemical constituents of medicinal plants from north-east region of India in genomic sequences

Bioinformation
2012 | Journal article
DOI: 10.6026/97320630008209
PMID: 22419844
Source: Self-asserted source
N. Prakash Prabhu

Protein-surfactant interaction: Sodium dodecyl sulfate-induced unfolding of ribonuclease A

Journal of Physical Chemistry B
2011 | Journal article
DOI: 10.1021/jp2062496
EID:

2-s2.0-83455225620
Contributors: Tejaswi Naidu, K.; Prakash Prabhu, N.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Extensive misfolding in the refolding reaction of alkaline ferrocytochrome c

Biochemistry
2006 | Journal article
DOI: 10.1021/bi060141z
EID:

2-s2.0-33745838251
Contributors: Rao, D.K.; Prabhu, N.P.; Bhuyan, A.K.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Prediction of folding rates of small proteins: Empirical relations based on length, secondary structure content, residue type, and stability

Biochemistry
2006 | Journal article
DOI: 10.1021/bi0521137
EID:

2-s2.0-33645240906
Contributors: Prabhu, N.P.; Bhuyan, A.K.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

The Alkali Molten Globule State of Horse Ferricytochrome c: Observation of Cold Denaturation

Journal of Molecular Biology
2006 | Journal article
DOI: 10.1016/j.jmb.2006.09.025
EID:

2-s2.0-33750828962
Contributors: Kumar, R.; Prabhu, N.P.; Rao, D.K.; Bhuyan, A.K.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Protein folding in classical perspective: Folding of horse cytochrome c

Biochemistry
2005 | Journal article
DOI: 10.1021/bi047897n
EID:

2-s2.0-14344261397
Contributors: Bhuyan, A.K.; Rao, D.K.; Prabhu, N.P.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Ultrafast events in the folding of ferrocytochrome c

Biochemistry
2005 | Journal article
DOI: 10.1021/bi050384b
EID:

2-s2.0-21644490060
Contributors: Kumar, R.; Prabhu, N.P.; Bhuyan, A.K.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Folding Barrier in Horse Cytochrome c: Support for a Classical Folding Pathway

Journal of Molecular Biology
2004 | Journal article
DOI: 10.1016/j.jmb.2004.01.016
EID:

2-s2.0-1442277673
Contributors: Prabhu, N.P.; Kumar, R.; Bhuyan, A.K.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Protein stiffening and entropic stabilization in the subdenaturing limit of guanidine hydrochloride.

Biophysical journal
2004 | Journal article
DOI: 10.1529/biophysj.104.044701
EID:

2-s2.0-14344262901
Contributors: Kumar, R.; Prabhu, N.P.; Yadaiah, M.; Bhuyan, A.K.
Source: Self-asserted source
N. Prakash Prabhu via Scopus - Elsevier

Peer review (23 reviews for 12 publications/grants)

Review activity for Anti-cancer agents in medicinal chemistry. (1)
Review activity for BBA advances. (1)
Review activity for Biochemical and biophysical research communications. (1)
Review activity for Food hydrocolloids. (1)
Review activity for International journal of biological macromolecules. (1)
Review activity for Journal of biomolecular structure and dynamics. (8)
Review activity for Journal of molecular graphics and modelling. (1)
Review activity for Journal of molecular modeling. (4)
Review activity for Journal of molecular modeling. (2)
Review activity for Molecular simulation. (1)
Review activity for Protein & peptide letters. (1)
Review activity for Royal Society open science. (1)
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