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Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10

Communications Biology
2022-12-01 | Journal article
DOI: 10.1038/s42003-022-04265-0
Contributors: Mohamed Ahmed; Jared Mackenzie; Liku Tezera; Robert Krause; Barry Truebody; Diana Garay-Baquero; Andres Vallejo; Katya Govender; John Adamson; Hayden Fisher et al.
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<i>Mycobacterium tuberculosis</i> H<sub>2</sub>S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility

Antioxidants
2021-08 | Journal article | Author
DOI: 10.3390/antiox10081285
Contributors: Tafara T.R. Kunota; Aejazur Rahman; Barry Truebody; jared Mackenzie; Vikram Saini; Dirk Lamprecht; John Howard Adamson; Ritesh Sevalkar; Jack R. Lancaster; Michael Berney et al.
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Multidisciplinary Digital Publishing Institute
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Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase

PLOS Pathogens
2021-07-28 | Journal article
DOI: 10.1371/journal.ppat.1008911
Contributors: Yi Cai; Helena Ingrid Boshoff; Eleni Jaecklein; Jared S. Mackenzie; Kadamba Papavinasasundaram; Andrew J. Olive; Xinchun Chen; Adrie J. C. Steyn; Christopher M. Sassetti
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Mycobacterium tuberculosis H2S functions as a sink to modulate central metabolism, bioenergetics, and drug susceptibility

2021-06-02 | Other
DOI: 10.1101/2021.06.02.446746
Contributors: Tafara T.R. Kunota; Md. Aejazur Rahman; Barry E. Truebody; Jared S. Mackenzie; Vikram Saini; Dirk A. Lamprecht; John H. Adamson; Ritesh R. Sevalkar; Jack R. Lancaster, Jr.; Michael Berney et al.
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Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis

EMBO Molecular Medicine
2021-01-11 | Journal article
DOI: 10.15252/emmm.202013207
Contributors: Bei Shi Lee; Kiel Hards; Curtis A Engelhart; Erik J Hasenoehrl; Nitin P Kalia; Jared S Mackenzie; Ekaterina Sviriaeva; Shi Min Sherilyn Chong; Malathy Sony S Manimekalai; Vanessa H Koh et al.
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Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis

Nature Communications
2020-11-30 | Journal article
DOI: 10.1038/s41467-020-19959-4
Contributors: Jared S. Mackenzie; Dirk A. Lamprecht; Rukaya Asmal; John H. Adamson; Khushboo Borah; Dany J. V. Beste; Bei Shi Lee; Kevin Pethe; Simon Rousseau; Inna Krieger et al.
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Host immunity increasesMycobacterium tuberculosisreliance on cytochromebdoxidase

2020-08-21 | Preprint
DOI: 10.1101/2020.08.21.260737
Contributors: Yi Cai; Eleni Jaecklein; Jared Mackenzie; Kadamba Papavinasasundaram; Andrew J. Olive; Xinchun Chen; Adrie Steyn; Christopher Sassetti
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