Personal information
Biography
Prof Alison Banham is currently Professor of Haemato-oncology and Head of the Nuffield Division of Clinical Laboratory Sciences, within the Radcliffe Department of Medicine at the University of Oxford.
Her academic qualifications include BA, MA and D.Phil. (PhD) degrees from the University of Oxford and Fellowship of the Royal College of Pathologists. Professor Banham is a member of the British Lymphoma Pathology Study Group and a founder member and currently Vice President of the European Network of Monoclonal Antibody Producing Laboratories.
Having originally studied Botany and then Biochemistry she was introduced to monoclonal antibody technology in 1990, through making antibodies for the detection of food spoilage fungi. Since 1995 her main research focus has been within the field of cancer, particularly lymphoma, focussing initially on the identification and characterisation of novel diagnostic and prognostic biomarkers and more recently, since 2009, expanding into novel antibody therapeutics.
Antibody therapeutics are focussed primarily of targeting the tumour vasculature, in particular the Notch signalling pathway and on the development of TCR mimic antibodies which recognise peptides from intracellular tumour proteins that are presented on the cell surface by MHC class I molecules. This work is supported by Cancer Research UK. Funding from Leukaemia and Lymphoma Research supports investigation into a family of forehead transcription factors that play a critical role in the pathogenesis of lymphoma and other types of cancer. These molecules play an important role in enabling tumour cells to evade the host immune response.
Prof Banham is happy to undertake outreach activities. She is a STEM Ambassador and a volunteer for the Inspiring the Future Campaign.
Activities
Employment (1)
Education and qualifications (5)
Works (50 of 114)
10.1371/journal.pone.0128513
26034982
10.1016/j.molcel.2015.03.031
25936801
10.1002/gcc.22242
25706801
10.1074/jbc.M115.638221
25987564
10.4137/BMI.S16553
25232277
PMC4159367
10.3389/fonc.2014.00254
25309874
PMC4174884
10.1042/BST20140216
25399586
10.1111/cea.12375
25048599
10.1111/jvh.12141
24597693
PMC4159582
10.1038/leu.2013.224
23884370
10.1016/j.ccr.2013.06.004
23871637
PMC3743050
10.1074/jbc.M112.428854
23339193
PMC3591638
10.1186/gb-2012-13-3-r24
22458515
PMC3439975
10.1016/j.jprot.2012.06.009
22732457
10.1371/journal.pone.0023916
21887344
PMC3161784
10.1159/000322845
21576985
10.1186/bcr2869
21521526
PMC3219210
10.3324/haematol.2010.028241
20851862
PMC3012768
20726502
PMC2964014
10.1038/leu.2010.196
20861911
10.1158/1078-0432.CCR-09-3216
20628029
10.1111/j.1365-2133.2010.09763.x
20302573
10.1111/j.1365-2141.2009.08070.x
20096010
10.1111/j.1365-2141.2009.07979.x
19961478
10.1136/ard.2008.100768
19066178
10.1200/JCO.2009.22.7058
19786664
10.1136/jcp.2009.065169
19622517
10.1200/JCO.2008.20.5450
19752343
PMC2799056
10.1158/1078-0432.CCR-09-0113
19706817
10.1111/j.1365-2141.2009.07761.x
19552722
10.1038/modpathol.2009.73
19448593
10.1517/13543770902785183
19456276
10.1111/j.1600-0609.2009.01222.x
19141121
10.1111/j.1365-2133.2009.09035.x
19222459
10.1093/hmg/ddn377
18996916
PMC2722192
10.1158/1078-0432.CCR-08-1507
19188178
10.1016/j.vetimm.2008.10.328
19084279
10.1517/14712590802494022
18990077
10.1007/s10549-007-9812-4
18026833
10.1038/leu.2008.166
18580954
10.1016/j.ygyno.2008.04.021
18533240
10.1038/modpathol.2008.74
18487996
10.1111/j.1365-2141.2008.07077.x
18318758
10.1158/1078-0432.CCR-07-4946
18445693
10.1111/j.1365-2559.2008.02990.x
18312343
10.1182/blood-2008-01-134148
18362214
10.1182/blood-2007-09-115113
18077790
10.1002/pros.20707
18163427
10.1111/j.1600-0609.2007.00990.x
18036183
17388261
PMC2935744