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Histone variants, Chromatin and epigenetics, Nuclear Organisation, Acute myeloid leukaemia, Drug targets

Biography

I have been trained in molecular cancer research and chromatin biology at several institutions that include the Max-Planck-Institute of Biochemistry, the University of Oxford and the Center of Genomic Regulation. In 2009, I have combined the two fields to start my own research group. At the Josep Carreras Institute, we try to bridge basic and applied research studying chromatin regulation and aim to identify novel combinatorial drug targets for the treatment of blood cancers.
For up to date information, please check out the website of my lab: https://buschbecklab.org

Activities

Employment (4)

Josep Carreras Institute (IJC): Badalona, ES

2015-01-01 to present | Group Leader (Program of Applied Epigenetic, Program of Myeloid Neoplasms)
Employment
Source: Self-asserted source
BUSCHBECK M.

Institute for Predictive and Personalized Medicine of Cancer (IMPPC): Badalona, ES

2009-01-09 to 2014-12-31 | Junior Group Leader
Employment
Source: Self-asserted source
BUSCHBECK M.

Centre for Genomic Regulation: Barcelona, ES

2003-12-01 to 2009-01-08 | Postdoc (Cancer and Differentiation Program)
Employment
Source: Self-asserted source
BUSCHBECK M.

Max Planck Institute of Biochemistry: Martinsried, DE

1998-12-01 to 2003-11-30 | PhD student (Dept. of Prof. Axel Ullrich)
Employment
Source: Self-asserted source
BUSCHBECK M.

Education and qualifications (2)

Goethe University Frankfurt: Frankfurt am Main, Hessen, DE

2000-09-15 to 2003-09-05 | Dr. phil. nat (PhD) (Faculty of Biochemistry and Pharmacy)
Education
Source: Self-asserted source
BUSCHBECK M.

Goethe University Frankfurt: Frankfurt am Main, Hessen, DE

1993-09-15 to 1998-09-28 | Diplom in Biochemistry (equiv. 300+ ECTS) (Biochemistry)
Education
Source: Self-asserted source
BUSCHBECK M.

Professional activities (24)

Clinical Epigenetic,Springer Nature: Germany, DE

2023-09 to present | Associate Editor
Membership
Source: Self-asserted source
BUSCHBECK M.

European Hematology Association: The Hague, NL

2023-06 to present (Research Committee)
Membership
Source: Self-asserted source
BUSCHBECK M.

European Hematology Association: The Hague, NL

2023 to present
Membership
Source: Self-asserted source
BUSCHBECK M.

Philanthropy Ohio: Barcelona, Ohio, ES

2017 to present | Panel Member
Membership
Source: Self-asserted source
BUSCHBECK M.

National Funding Agency ANR: Paris, FR

2015 to present
Membership
Source: Self-asserted source
BUSCHBECK M.

University of Zurich: Zurich, CH

2014 to present | External member, TAB incl
Membership
Source: Self-asserted source
BUSCHBECK M.

Reviewer for funding agencies incl. ERC, MRC-UK, and ANR-France: Barcelona, ES

2010 to present
Membership
Source: Self-asserted source
BUSCHBECK M.

University of Oslo: Oslo, NO

2009 to present | Thesis defense committee member incl. UB, UAB, UPF
Membership
Source: Self-asserted source
BUSCHBECK M.

Nature Structural & Molecular Biology, Jounral: New York, US

2009 to present | Rewier
Membership
Source: Self-asserted source
BUSCHBECK M.

Journals of Nature Cell Biology, Nature Communications and Science Advances: New York, US

2009 to present | Reviewer
Membership
Source: Self-asserted source
BUSCHBECK M.

Catalan Society of Biology: Barcelona, ES

2008 to present
Membership
Source: Self-asserted source
BUSCHBECK M.

EpiGene3Sys: FRANCE, FR

2022 to 2026 | Associated partner
Membership
Source: Self-asserted source
BUSCHBECK M.

COST CA21135 – IMMUNO-Model: Brussels, BE

2022 to 2026
Membership
Source: Self-asserted source
BUSCHBECK M.

COST CA18127 International Nucleome Consortium: Brussels, BE

2019 to 2023
Membership
Source: Self-asserted source
BUSCHBECK M.

RedINC, Spanish Nucleome Networ: Spain, ES

2019 to 2022
Membership
Source: Self-asserted source
BUSCHBECK M.

Internal Scientific Advisory Committee,IGTP: Barcelona, ES

2018 to 2021
Membership
Source: Self-asserted source
BUSCHBECK M.

LifeTime, CSA of EU FET Flagship initiative: Barcelona, ES

2019 to 2020
Membership
Source: Self-asserted source
BUSCHBECK M.

Funding and evaluation panel, BW Stiftung: Stuttgart, DE

2018 to 2020
Membership
Source: Self-asserted source
BUSCHBECK M.

COST CM1406 Epigenetic Chemical Biology: Brussels, BE

2015 to 2019
Membership
Source: Self-asserted source
BUSCHBECK M.

Society for Biochemistry and Molecular Biology (GBM): Frankfurt, DE

2004 to 2017
Membership
Source: Self-asserted source
BUSCHBECK M.

Catalan Cancer Epigenetics Network between institutions in Freiburg, Heidelberg and Barcelona: Heidelberg, DE

2013 to 2016 | Co-initiator
Membership
Source: Self-asserted source
BUSCHBECK M.

Network of Excellence EpiGeneSys: Paris, FR

2012 to 2016
Membership
Source: Self-asserted source
BUSCHBECK M.

COST TD0905 Epigenetics: Bench to Bedside,: Brussels, BE

2013 to 2014
Membership
Source: Self-asserted source
BUSCHBECK M.

FP7 InterPod program, CRG: Barcelona, ES

2011 to 2012 | Selection Panel
Membership
Source: Self-asserted source
BUSCHBECK M.

Funding (44)

EPISTROMA - Epigenetic re-education of the bone marrow stroma niche as a therapeutic approach for preventing blood cancer

2022-12 to 2025-12 | Grant
AECC (Call PROYECTOS GENERALES AECC 2022) (Barcelona, ES)
GRANT_NUMBER:

PRYGN222668BUSC

Source: Self-asserted source
BUSCHBECK M.

NucleoSense - Enhancer regulation and nuclear metabolite sensing by histone variants

2022-09 to 2025-08 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

PID2021-126907NB-I00

Source: Self-asserted source
BUSCHBECK M.

Walter Benjamin

2022-05 to present | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER:

Geschäftszeichen: WI 5839/1-1

Source: Self-asserted source
BUSCHBECK M.

Exploring epigenetic modulation in bone marrow stroma as novel therapeutic approach to prevent leukaemia

2022-01-01 to present | Grant
Deutsche Forschungsgemeinschaft (Bonn, DE)
GRANT_NUMBER: 498523371
Source: Self-asserted source
BUSCHBECK M. via DimensionsWizard

Moving Epigenetics Towards Systems Biology – EpiGene3Sys

2022-01 to 2026-12 | Grant
French National Centre for Scientific Research (Paris, FR)
Source: Self-asserted source
BUSCHBECK M.

Exploring novel drug actions of CCS1477 for the identification of combinatorial drug targets and response-predicting parameters.

2021-10 to 2022-04 | Contract
CellCentric Ltd (Londres, GB)
Source: Self-asserted source
BUSCHBECK M.

INTERCEPT-MDS: Exploring cell-to-cell heterogeneity and exploiting epigenetic regulation for the interception of myeloid disease cells

2021-01 to 2024-12 | Grant
European Commission (Brussels, BE)
GRANT_NUMBER:

H2020-MSCA-ITN-2020-953407

Source: Self-asserted source
BUSCHBECK M.

Exploring and exploiting histone variants as drug targets in acute myeloid leukaemia

2021-01 to 2024-01 | Grant
Fundació La Marató de TV3 (Barcelona, ES)
GRANT_NUMBER:

201907-30-31

Source: Self-asserted source
BUSCHBECK M.

RedINC: Spanish network of the International Nucleome Consortium

2021-01 to 2022-12 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

RED2018-102801-T

Source: Self-asserted source
BUSCHBECK M.

PTA – Cofunded technician contract for Raquel Casquero

2019-12 to 2021 | Grant
MINECO (Madrid, ES)
GRANT_NUMBER:

PTA2017-13669-I

Source: Self-asserted source
BUSCHBECK M.

COST action CA18127 - International Nucleome Consortium

2019-05 to 2023-04 | Grant
European Commission (Brussels, BE)
Source: Self-asserted source
BUSCHBECK M.

Regulation of 3D chromatin architecture by histone variants and their metabolite binding capacity

2019-01 to 2022-09 | Grant
Ministerio de Ciencia y Tecnología (madrid, ES)
GRANT_NUMBER:

RTI2018-094005-B-I00

Source: Self-asserted source
BUSCHBECK M.

Grups de Recerca (Preconsolidat) – Chromatin, Metabolism and Cell Fate

2019-01 to 2021-12 | Grant
AGAUR (Barcelona, ES)
GRANT_NUMBER:

2017 SGR 305

Source: Self-asserted source
BUSCHBECK M.

Sara Borrell - Postdoctoral long-term fellowship for Dr. Jeannine Diesch

2018-01 to 2022-01 | Grant
Ministerio de Ciencia y Tecnología (Madrid, ES)
GRANT_NUMBER:

CD17/00084

Source: Self-asserted source
BUSCHBECK M.

Proyecto Integrado de Excelencia – RESPONSE - Biomarkers and combinatorial drug targets for a personalized therapy for three major cancers.

2017-01 to 2021-06 | Grant
MINECO (Madrid, ES)
GRANT_NUMBER:

PIE16/00011

Source: Self-asserted source
BUSCHBECK M.

FPI predoctoral fellowship for Margurite-Marie Le Pannérer

2017-01 to 2020-12 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

BES-2016-077251

Source: Self-asserted source
BUSCHBECK M.

Exploratory study to determine the molecular criteria of response to VIDAZA®treatment

2017-01 to 2017-12 | Grant
CELGENE Spain, S.L. (Madrid, ES)
Source: Self-asserted source
BUSCHBECK M.

Chromatin and Metabolism Chromatin-metabolism interactions as targets for healthy living

2016-03-01 to 2020-02-29 | Grant
European Commission (Brussels, BE)
GRANT_NUMBER: 675610
Source: Self-asserted source
BUSCHBECK M. via DimensionsWizard

Histone variants link metabolism and nuclear architecture

2016-01 to 2018-12 | Grant
MINECO (Madrid, ES)
GRANT_NUMBER:

BFU2015-66559-P

Source: Self-asserted source
BUSCHBECK M.

Identification of chromatin biomarkers for predicting and sensitizing response to current treatments in colorectal cancer.

2016-01 to 2017-12 | Grant
Fundación Olga Torres (Barcelona, ES)
Source: Self-asserted source
BUSCHBECK M.

Juan de la Cierva - Postdoctoral long-term fellowship for Dr. Jeannine Diesch

2016-01 to 2017-12 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

FJCI-2014-22983

Source: Self-asserted source
BUSCHBECK M.

FPU predoctoral fellowship and contract for David Corujo

2015-09 to 2019-09 | Grant
Ministerio de Universidades (Madrid, ES)
GRANT_NUMBER:

FPU14/06542

Source: Self-asserted source
BUSCHBECK M.

Dissecting the Role of Polycomb Complexes in the Pathogenesis of Myelodysplastic Syndromes (MDS) and the Evolution to Acute Myeloid Leukemia

2015-08 to 2017-07 | Grant
Deutsche José Carreras Leukämie-Stiftung (Munich, DE)
GRANT_NUMBER:

DJCLS R 14/16

Source: Self-asserted source
BUSCHBECK M.

How does the histone variant macroH2A regulate muscle metabolism in health and disease

2015-02 to 2017-02 | Grant
AFM-Téléthon (Paris, FR)
Source: Self-asserted source
BUSCHBECK M.

Reposicionamiento de fármacos como un enfoque rápido y rentable hacia terapias personalizadas. Estudio piloto en síndromes mielodisplásicos y leucemia mieloblástica aguda

2014-02 to 2016-03 | Grant
AECC-Junta de Barcelona (BARCELONA, ES)
Source: Self-asserted source
BUSCHBECK M.

Collaborative FIRC fellowship for Stefano Cacciatore

2013-06 to 2014-05 | Grant
AIRC - Italian Association for Cancer Research (Milan, IT)
Source: Self-asserted source
BUSCHBECK M.

Epigenetic Regulators of Stem Cell Function

2013-01 to 2015-12 | Grant
MINECO (Madrid, ES)
GRANT_NUMBER:

SAF2012-39749

Source: Self-asserted source
BUSCHBECK M.

Juan de la Cierva post-doctoral work contract to Dr. Julien Douet

2012-06 to 2015-05 | Grant
Ministerio de Ciencia y Tecnología (madrid, ES)
GRANT_NUMBER:

JCI-2011-10831

Source: Self-asserted source
BUSCHBECK M.
grade
Preferred source (of 2)‎

Ramón y Cajal Fellowship and grant

2010-12 to 2015-11 | Grant
MICINN (Madrid, ES)
GRANT_NUMBER:

RYC2010-07337

Source: Self-asserted source
BUSCHBECK M.

Beatriu de Pinós - Postdoctoral long-term fellowship

2010-09 to 2012-05 | Grant
AGUAR (Barcelona, ES)
Source: Self-asserted source
BUSCHBECK M.

Beatriu de Pinós post-doctoral work contract to Dr. Julien Douet

2010-09 to 2012-05 | Grant
AGAUR (BARCELONA, ES)
Source: Self-asserted source
BUSCHBECK M.

A histone variant regulating cell fate

2010-01 to 2013-12 | Grant
MICINN (Madrid, ES)
GRANT_NUMBER:

SAF2009-08496

Source: Self-asserted source
BUSCHBECK M.

FEBS - Postdoctoral long-term fellowship for Dr. Catherine Creppe

2010-01 to 2012-12 | Grant
Federation of European Biochemical Societies (Cambridge, GB)
Source: Self-asserted source
BUSCHBECK M.

EMBO - Postdoctoral long-term fellowship for Dr. Catherine Creppe

2009-07 to 2009-12 | Grant
EMBO (Heidelberg, DE)
Source: Self-asserted source
BUSCHBECK M.

EMBO - Postdoctoral long-term fellowship for Dr. Catherine Creppe

2009-07 to 2009-12 | Grant
EMBO (Munich, DE)
Source: Self-asserted source
BUSCHBECK M.

EMBO - Postdoctoral long-term fellowship for Dr. Catherine Creppe

2009-07 to 2009-12 | Grant
EMBO (Munich, DE)
Source: Self-asserted source
BUSCHBECK M.

CONSOLIDER Epigenetics: Mechanisms and Disease (EPIGENETICA)

2006-11 to 2011-10 | Grant
CONSOLIDER - INGENIO 2010 (Madrid, ES)
Source: Self-asserted source
BUSCHBECK M.

Oncogene co-operation in leukemia progression

2006-09 to 2009-08 | Grant
FUNDACIÓ MARATÓ TV3 (Barcelona, ES)
Source: Self-asserted source
BUSCHBECK M.

Events Epigenètics en Càncer, Programa Diferenciació i Càncer

2005-01 to 2008-12 | Grant
AGAUR (Barcelona, ES)
Source: Self-asserted source
BUSCHBECK M.

El papel de la alteración de la chromatina en la leucemia

2004-12 to 2007-12 | Grant
MECD (Madrid, ES)
Source: Self-asserted source
BUSCHBECK M.

Genética y Epigenética en la Leucemia

2004-10 to 2007-12 | Grant
FUNDACION LA CAIXA (Barcelona, ES)
Source: Self-asserted source
BUSCHBECK M.

CarrerasLeaders: Postdoctoral Program - Empowering Future Leaders to Fight Blood Cancers

Grant
European Commission (Brussels, BE)
GRANT_NUMBER:

HORIZON-MSCA-2021-COFUND-01-101081347

Source: Self-asserted source
BUSCHBECK M.

CarrerasPathfinders: Doctoral Program - Enabling the next generation in search of blood cancer cures

Grant
European Commission (Brussels, BE)
GRANT_NUMBER:

HORIZON-MSCA-2022-COFUND-01-101126688

Source: Self-asserted source
BUSCHBECK M.

PRE – predoctoral fellowship for Oliver Meers (PRE2019-088529) associated with RTI2018-094005-B-I00

Grant
MINECO (Madrid, ES)
GRANT_NUMBER:

PRE2019-088529

Source: Self-asserted source
BUSCHBECK M.

Peer review (36 reviews for 19 publications/grants)

Review activity for Antioxidants. (2)
Review activity for BMC biology. (2)
Review activity for Cancers. (2)
Review activity for Cell death and differentiation. (1)
Review activity for Cell reports. (1)
Review activity for Cells. (6)
Review activity for Cellular and molecular life sciences (1)
Review activity for Clinical epigenetics (2)
Review activity for Epigenetics & chromatin. (2)
Review activity for International journal of molecular sciences. (2)
Review activity for Leukemia (2)
Review activity for Molecular cell. (1)
Review activity for Nature cell biology (1)
Review activity for Nature reviews. (1)
Review activity for Nature reviews. (1)
Review activity for Nucleic acids research. (4)
Review activity for Oncogene. (2)
Review activity for PloS one. (2)
Review activity for Therapeutic advances in hematology. (1)