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Funding (1)

Exploration of novel gene therapies for inherited retinal degenerations

Award
Irish Research Council (Dublin, IE)
Source: Self-asserted source
Laura K. Finnegan

Works (8)

Novel Splice-Altering Variants in the CHM and CACNA1F Genes Causative of X-Linked Choroideremia and Cone Dystrophy

Genes
2024-12-27 | Journal article
DOI: 10.3390/genes16010025
Contributors: Anna R. Ridgeway; Ciara Shortall; Laura K. Finnegan; Róisín Long; Evan Matthews; Adrian Dockery; Ella Kopčić; Laura Whelan; Claire Kirk; Giuliana Silvestri et al.
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AAV-NDI1 Therapy Provides Significant Benefit to Murine and Cellular Models of Glaucoma

International Journal of Molecular Sciences
2024-08-15 | Journal article
DOI: 10.3390/ijms25168876
Contributors: Sophia Millington-Ward; Arpad Palfi; Ciara Shortall; Laura K. Finnegan; Ethan Bargroff; Iris J. M. Post; John Maguire; Mustapha Irnaten; Colm O′Brien; Paul F. Kenna et al.
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RPE-Directed Gene Therapy Improves Mitochondrial Function in Murine Dry AMD Models

International Journal of Molecular Sciences
2023-02-14 | Journal article
DOI: 10.3390/ijms24043847
Contributors: Sophia Millington-Ward; Naomi Chadderton; Laura K. Finnegan; Iris J. M. Post; Matthew Carrigan; Rachel Nixon; Marian M. Humphries; Pete Humphries; Paul F. Kenna; Arpad Palfi et al.
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Optimisation of AAV-NDI1 Significantly Enhances Its Therapeutic Value for Correcting Retinal Mitochondrial Dysfunction

Pharmaceutics
2023-01-18 | Journal article
DOI: 10.3390/pharmaceutics15020322
Contributors: Naomi Chadderton; Arpad Palfi; Daniel M. Maloney; Matthew Carrigan; Laura K. Finnegan; Killian S. Hanlon; Ciara Shortall; Mary O’Reilly; Peter Humphries; Lorraine Cassidy et al.
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SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration

International Journal of Molecular Sciences
2022-01-30 | Journal article
DOI: 10.3390/ijms23031606
Contributors: Laura K. Finnegan; Naomi Chadderton; Paul F. Kenna; Arpad Palfi; Michael Carty; Andrew G. Bowie; Sophia Millington-Ward; G. Jane Farrar
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Novel 199 base pair NEFH promoter drives expression in retinal ganglion cells.

Scientific reports
2020-10-05 | Journal article
DOI: 10.1038/s41598-020-73257-z
PMID: 33020509
PMC: PMC7536420
Source: Self-asserted source
Laura K. Finnegan

Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1

Human Molecular Genetics
2020-02-10 | Journal article
DOI: 10.1093/hmg/ddaa021
Part of ISSN: 0964-6906
Part of ISSN: 1460-2083
Source: Self-asserted source
Laura K. Finnegan

lncRNAs, DNA Methylation, and the Pathobiology of Exfoliation Glaucoma

Journal of Glaucoma
2018-03 | Journal article
DOI: 10.1097/ijg.0000000000000711
Part of ISSN: 1057-0829
Source: Self-asserted source
Laura K. Finnegan
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