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SciProfiles: 1094129

Keywords

tumor immunology, T cells, immunotherapy, immune biomarkers

Countries

France, United States

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Employment (4)

University of California, San Diego: San Diego, US

2019-09 to present | Assistant Project Scientist (Medicine)
Employment
Source: Self-asserted source
Magalie DOSSET

INSERM UMR1098 - University Bourgogne Franche-Comté: Besançon, FR

2016-09 to 2020-01 | Postdoctoral researcher (Immunomolecular therapeutics for cancers)
Employment
Source: Self-asserted source
Magalie DOSSET

INSERM UMR1231: Dijon, FR

2012-12 to 2016-09 | Postdoctoral researcher (UMR1231 - Lipid, Nutrition, Cancer)
Employment
Source: Self-asserted source
Magalie DOSSET

INSERM UMR970/UMR1098 - University Bourgogne Franche-Comté: Besançon, FR

2009-01 to 2013-06 | PhD student (Immunomolecular therapeutics for cancers)
Employment
Source: Self-asserted source
Magalie DOSSET

Education and qualifications (5)

University of California, San Diego: San Diego, US

2023-03-13 | Certificate in Applied Bioinformatics (Division of Extended Studies)
Education
Source: Self-asserted source
Magalie DOSSET

University of Franche-Comté: Besançon, FR

2012-12-03 | Doctor in Immunology, PhD
Education
Source: Self-asserted source
Magalie DOSSET

École Nationale Vétérinaire d'Alfort: Maisons-Alfort, Île-de-France, FR

2010 | Animal Experimentation, Level I
Education
Source: Self-asserted source
Magalie DOSSET

Université Pierre et Marie Curie - Faculté de Médecine: Paris, Île-de-France, FR

2008 | Master of Molecular and Cellular Biology
Education
Source: Self-asserted source
Magalie DOSSET

Institut Pasteur: Paris, FR

2008 | Diploma of Advanced Immunology
Education
Source: Self-asserted source
Magalie DOSSET

Professional activities (2)

Society for Immunotherapy of Cancer: Milwaukee, Wisconsin, US

2022-03-31 to present | Scientist-in-Training Membership
Membership
Source: Self-asserted source
Magalie DOSSET

University of California San Diego Moores Cancer Center: La Jolla, CA, US

2019-09-04 to 2022-09-03 | Visiting Assistant Project Scientist (Medecine)
Invited position
Source: Self-asserted source
Magalie DOSSET

Works (27)

Transcriptional analysis links B cells and TERT expression to favorable prognosis in head and neck cancer

PNAS Nexus
2023-03-03 | Journal article | Author
DOI: 10.1093/pnasnexus/pgad046
Part of ISSN: 2752-6542
Contributors: Su Xian; Magalie DOSSET; Andrea Castro; Hannah Carter; Maurizio Zanetti
Source: Self-asserted source
Magalie DOSSET

Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity

Interdisciplinary Cancer Research
2022 | Book chapter
DOI: 10.1007/16833_2022_49
Part of ISBN: 9783031324574
Part of ISBN: 9783031324581
Part of ISSN: 2731-4561
Part of ISSN: 2731-457X
Contributors: Magalie Dosset; Andrea Castro; Su Xian; Hannah Carter; Maurizio Zanetti
Source: Self-asserted source
Magalie DOSSET

Disulfiram's journey from rubber vulcanization to T‐cell activation

The EMBO Journal
2022-08-16 | Journal article | Author
DOI: 10.15252/embj.2022111862
Part of ISSN: 0261-4189
Part of ISSN: 1460-2075
Contributors: Magalie DOSSET; Maurizio Zanetti
Source: Self-asserted source
Magalie DOSSET

The Unfolded Protein Response at the Tumor-Immune Interface

Frontiers in Immunology
2022-02-14 | Journal article
DOI: 10.3389/fimmu.2022.823157
Part of ISSN: 1664-3224
Source: Self-asserted source
Magalie DOSSET

The unfolded protein response links tumor aneuploidy to local immune dysregulation

EMBO reports
2021-12-06 | Journal article
DOI: 10.15252/embr.202152509
Part of ISSN: 1469-221X
Part of ISSN: 1469-3178
Source: Self-asserted source
Magalie DOSSET

Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint inhibitors therapy

Journal for ImmunoTherapy of Cancer
2021-07 | Journal article
DOI: 10.1136/jitc-2020-002256
Part of ISSN: 2051-1426
Source: Self-asserted source
Magalie DOSSET

Modulation of Determinant Factors to Improve Therapeutic Combinations with Immune Checkpoint Inhibitors

Cells
2020-07 | Journal article | Author
DOI: 10.3390/cells9071727
Contributors: Magalie DOSSET; Elodie Lauret-Marie Joseph; Thaiz Rivera Vargas; Lionel Apetoh
Source: check_circle
Multidisciplinary Digital Publishing Institute

Telomerase and CD4 T Cell Immunity in Cancer

Cancers
2020-06-25 | Journal article | Author
DOI: 10.3390/cancers12061687
Part of ISSN: 2072-6694
Contributors: Magalie DOSSET; Andrea Castro; Hannah Carter; Maurizio Zanetti
Source: Self-asserted source
Magalie DOSSET
grade
Preferred source (of 2)‎

Immunoregulation and Clinical Implications of ANGPT2/TIE2+ M-MDSC Signature in Non-Small Cell Lung Cancer.

Cancer immunology research
2019-12 | Journal article
DOI: 10.1158/2326-6066.cir-19-0326
PMID: 31871121
Contributors: Lauret Marie Joseph E; Laheurte C; Jary M; Boullerot L; Asgarov K; Gravelin E; Bouard A; Rangan L; Dosset M; Borg C et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance.

Cancer research
2019-10 | Journal article
DOI: 10.1158/0008-5472.can-19-0840
PMID: 31611309
Contributors: Bernard A; Chevrier S; Beltjens F; Dosset M; Viltard E; Lagrange A; Derangère V; Oudot A; Ghiringhelli F; Collin B et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Distinct prognostic value of circulating anti-telomerase CD4+ Th1 immunity and exhausted PD-1+/TIM-3+ T cells in lung cancer.

British Journal of Cancer
2019-07 | Journal article
DOI: 10.1038/s41416-019-0531-5
PMID: 31358938
PMC: PMC6738094
Contributors: Laheurte C; Dosset M; Vernerey D; Boullerot L; Gaugler B; Gravelin E; Kaulek V; Jacquin M; Cuche L; Eberst G et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Circulating NKp46+ Natural Killer cells have a potential regulatory property and predict distinct survival in Non-Small Cell Lung Cancer.

Oncoimmunology
2018-10 | Journal article
DOI: 10.1080/2162402x.2018.1527498
PMID: 30713781
PMC: PMC6343773
Contributors: Picard E; Godet Y; Laheurte C; Dosset M; Galaine J; Beziaud L; Loyon R; Boullerot L; Lauret Marie Joseph E; Spehner L et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment.

Oncotarget
2018-10 | Journal article
DOI: 10.18632/oncotarget.26247
PMID: 30459932
PMC: PMC6226040
Contributors: Vrecko S; Guenat D; Mercier-Letondal P; Faucheu H; Dosset M; Royer B; Galaine J; Boidot R; Kim S; Jary M et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer.

Oncoimmunology
2018-03 | Journal article
DOI: 10.1080/2162402x.2018.1433981
PMID: 29872568
PMC: PMC5980491
Contributors: Dosset M; Vargas TR; Lagrange A; Boidot R; Végran F; Roussey A; Chalmin F; Dondaine L; Paul C; Lauret Marie-Joseph E et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells.

Nature communications
2017-09 | Journal article
DOI: 10.1038/s41467-017-00468-w
PMID: 28916785
PMC: PMC5602674
Contributors: Rivera Vargas T; Cai Z; Shen Y; Dosset M; Benoit-Lizon I; Martin T; Roussey A; Flavell RA; Ghiringhelli F; Apetoh L
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Identification of a novel PD-L1 positive solid tumor transplantable in HLA-A*0201/DRB1*0101 transgenic mice.

Oncotarget
2017-07 | Journal article
DOI: 10.18632/oncotarget.16900
PMID: 28430664
PMC: PMC5564740
Contributors: Rangan L; Galaine J; Boidot R; Hamieh M; Dosset M; Francoual J; Beziaud L; Pallandre JR; Lauret Marie Joseph E; Asgarova A et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4(+) Th1 responses against telomerase in cancer patients.

Oncoimmunology
2016-02 | Journal article
DOI: 10.1080/2162402x.2015.1137416
PMID: 27467955
PMC: PMC4910811
Contributors: Laheurte C; Galaine J; Beziaud L; Dosset M; Kerzerho J; Jacquemard C; Gaugler B; Ferrand C; Dormoy A; Aubin F et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Immunogenicity evaluation of a rationally designed polytope construct encoding HLA-A*0201 restricted epitopes derived from Leishmania major related proteins in HLA-A2/DR1 transgenic mice: steps toward polytope vaccine.

PloS one
2014-10 | Journal article
DOI: 10.1371/journal.pone.0108848
PMID: 25310094
PMC: PMC4195657
Contributors: Seyed N; Taheri T; Vauchy C; Dosset M; Godet Y; Eslamifar A; Sharifi I; Adotevi O; Borg C; Rohrlich PS et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells.

Nature immunology
2014-06 | Journal article
DOI: 10.1038/ni.2925
PMID: 24973819
Contributors: Végran F; Berger H; Boidot R; Mignot G; Bruchard M; Dosset M; Chalmin F; Rébé C; Dérangère V; Ryffel B et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Universal tumor-reactive helper peptides from telomerase as new tools for anticancer vaccination.

Oncoimmunology
2013-03 | Journal article
DOI: 10.4161/onci.23430
PMID: 23802085
PMC: PMC3661170
Contributors: Dosset M; Vauchy C; Beziaud L; Adotevi O; Godet Y
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Targeting antitumor CD4 helper T cells with universal tumor-reactive helper peptides derived from telomerase for cancer vaccine.

Human vaccines & immunotherapeutics
2013-01 | Journal article
DOI: 10.4161/hv.23587
PMID: 23357860
PMC: PMC3899142
Contributors: Adotévi O; Dosset M; Galaine J; Beziaud L; Godet Y; Borg C
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer?

Oncoimmunology
2012-12 | Journal article
DOI: 10.4161/onci.21513
PMID: 23264913
PMC: PMC3525622
Contributors: Godet Y; Dosset M; Borg C; Adotevi O
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Universal cancer peptide-based therapeutic vaccine breaks tolerance against telomerase and eradicates established tumor.

Clinical cancer research : an official journal of the American Association for Cancer Research
2012-10 | Journal article
DOI: 10.1158/1078-0432.ccr-12-0896
PMID: 23032748
Contributors: Dosset M; Godet Y; Vauchy C; Beziaud L; Lone YC; Sedlik C; Liard C; Levionnois E; Clerc B; Sandoval F et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Analysis of spontaneous tumor-specific CD4 T-cell immunity in lung cancer using promiscuous HLA-DR telomerase-derived epitopes: potential synergistic effect with chemotherapy response.

Clinical cancer research : an official journal of the American Association for Cancer Research
2012-03 | Journal article
DOI: 10.1158/1078-0432.ccr-11-3185
PMID: 22407833
Contributors: Godet Y; Fabre E; Dosset M; Lamuraglia M; Levionnois E; Ravel P; Benhamouda N; Cazes A; Le Pimpec-Barthes F; Gaugler B et al.
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Immunogenicity of a recombinant lentiviral vector carrying human telomerase tumor antigen in HLA-B*0702 transgenic mice.

Vaccine
2010-07 | Journal article
DOI: 10.1016/j.vaccine.2010.06.071
PMID: 20654669
Contributors: Rusakiewicz S; Dosset M; Mollier K; Souque P; Charneau P; Wain-Hobson S; Langlade-Demoyen P; Adotévi O
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

The angiogenic growth factor and biomarker midkine is a tumor-shared antigen.

Journal of immunology (Baltimore, Md. : 1950)
2010-05 | Journal article
DOI: 10.4049/jimmunol.0901014
PMID: 20511550
Contributors: Kerzerho J; Adotevi O; Castelli FA; Dosset M; Bernardeau K; Szely N; Lang F; Tartour E; Maillere B
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo.

Blood
2010-02 | Journal article
DOI: 10.1182/blood-2009-11-253641
PMID: 20130242
Contributors: Adotévi O; Mollier K; Neuveut C; Dosset M; Ravel P; Fridman WH; Tartour E; Charneau P; Wain-Hobson S; Langlade-Demoyen P
Source: Self-asserted source
Magalie DOSSET via Europe PubMed Central

Peer review (6 reviews for 6 publications/grants)

Review activity for Cancers. (1)
Review activity for Cells. (1)
Review activity for Communications biology. (1)
Review activity for Genes and immunity (1)
Review activity for International journal of molecular sciences. (1)
Review activity for Pathogens. (1)
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