Personal information

Verified email addresses

Verified email domains

Stem Cells, Mitochondrion, Cancer, Neuron, Cell biology, Metabolism
Norway

Activities

Employment (1)

University of Bergen: Bergen, Hordaland, NO

2022-10-01 to present | Senior Researcher/Principal investigator (Department of Clinical Medicine (K1))
Employment
Source: Self-asserted source
Kristina Xiao Liang

Education and qualifications (1)

University of Bergen: Bergen, Hordaland, NO

2008-08-15 to 2013-06-08 | PhD
Education
Source: Self-asserted source
Kristina Xiao Liang

Works (40)

Hallmark Molecular and Pathological Features of POLG Disease are Recapitulated in Cerebral Organoids

Advanced Science
2024-05 | Journal article
Contributors: Anbin Chen; Tsering Yangzom; Yu Hong; Bjørn Christian Lundberg; Gareth John Sullivan; Charalampos Tzoulis; Laurence A. Bindoff; Kristina Xiao Liang
Source: check_circle
Crossref
grade
Preferred source (of 4)‎

The application of brain organoid for drug discovery in mitochondrial diseases

The International Journal of Biochemistry & Cell Biology
2024-05 | Journal article
Contributors: Kristina Xiao Liang
Source: check_circle
Crossref

Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies.

The journals of gerontology. Series A, Biological sciences and medical sciences
2024-04-01 | Journal article
Contributors: He-Ling Wang; Siow R; Schmauck-Medina T; Zhang J; Sandset PM; Filshie C; Lund Ø; Partridge L; Bergersen LH; Juel Rasmussen L et al.
Source: Self-asserted source
Kristina Xiao Liang

Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies.

Mitochondrion
2024-02-07 | Journal article
Contributors: Xiao Liang K
Source: Self-asserted source
Kristina Xiao Liang

The NAD<sup>+</sup> Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers' Disease.

International journal of biological sciences
2024-01-25 | Journal article
Contributors: Hong Y; Zhang Z; Yangzom T; Chen A; Lundberg BC; Fang EF; Siller R; gareth sullivan; Zeman J; Tzoulis C et al.
Source: Self-asserted source
Kristina Xiao Liang

Nicotinamide Riboside Supplementation Ameliorates Mitochondrial Dysfunction and Neuronal Loss in POLG Mutant Midbrain Organoids

2023-11-11 | Preprint
Contributors: Tsering Yangzom; Anbin Chen; Gareth John Sullivan; Kristina Xiao Liang
Source: check_circle
Crossref

Deoxyribonucleoside treatment rescues EtBr‐induced mtDNA depletion in iPSC‐derived neural stem cells with POLG mutations

The FASEB Journal
2023-09 | Journal article
Contributors: Cecilie Katrin Kristiansen; Jessica Furriol; Anbin Chen; Gareth John Sullivan; Laurence A. Bindoff; Kristina Xiao Liang
Source: check_circle
Crossref

Mitochondrial Dysfunction and Neuronal Anomalies inPOLGMutant Midbrain Organoids

2023-09-27 | Preprint
Contributors: Anbin Chen; Tsering Yangzom; Gareth John Sullivan; Kristina Xiao Liang
Source: check_circle
Crossref

Application of Flow Cytometric Analysis for Measuring Multiple Mitochondrial Parameters in 3D Brain Organoids

Journal of Visualized Experiments
2023-08-04 | Journal article
Part of ISSN: 1940-087X
Contributors: Sharika Marjan; Tsering Yangzom; Cecilie Katrin Kristiansen; Anbin Chen; Laurence A. Bindoff; Kristina Xiao Liang
Source: Self-asserted source
Kristina Xiao Liang

Inhibition of autophagy reduces the rate of fluoride‐induced LS8 apoptosis via regulating ATG5 and ATG7

Journal of Biochemical and Molecular Toxicology
2023-03 | Journal article
Part of ISSN: 1095-6670
Part of ISSN: 1099-0461
Contributors: Lin Zhao; Han Wang; Sijia Liu; Tao Xi; Liyuan Wang; Yang Li; Lu Chen; Jianping Ruan; Kristina Xiao Liang
Source: Self-asserted source
Kristina Xiao Liang

POLG genotype influences degree of mitochondrial dysfunction in iPSC derived neural progenitors, but not the parent iPSC or derived glia

2023-01-29 | Preprint
Contributors: Yu Hong; Cecilie Katrin Kristiansen; Anbin Chen; Gonzalo S. Nido; Lena Elise Høyland; Mathias Ziegler; Gareth John Sullivan; Laurence A. Bindoff; Kristina Xiao Liang
Source: check_circle
Crossref

Comparing the mitochondrial signatures in ESCs and iPSCs and their neural derivations

Cell Cycle
2022-10-18 | Journal article
Contributors: Cecilie Katrin Kristiansen; Anbin Chen; Lena Elise Høyland; Mathias Ziegler; Gareth John Sullivan; Laurence A. Bindoff; Kristina Xiao Liang
Source: check_circle
Crossref

Flow Cytometric Analysis of Multiple Mitochondrial Parameters in Human Induced Pluripotent Stem Cells and Their Neural and Glial Derivatives

Journal of Visualized Experiments
2021-11-08 | Journal article
Part of ISSN: 1940-087X
Contributors: Kristina Xiao Liang; Anbin Chen; Cecilie Katrin Kristiansen; Laurence A. Bindoff
Source: Self-asserted source
Kristina Xiao Liang

Ferroptosis Holds Novel Promise in Treatment of Cancer Mediated by Non-coding RNAs.

Frontiers in cell and developmental biology
2021-06-21 | Journal article
Contributors: Zhi Y; Gao L; Wang B; Ren W; Liang KX; Zhi K
Source: Self-asserted source
Kristina Xiao Liang

MAP kinase phosphatase MKP-1 regulates p-ERK1/2 signaling pathway with fluoride treatment

Biochemical and Biophysical Research Communications
2021-02 | Journal article
Contributors: Lin Zhao; Jiali Su; Sijia Liu; Yang Li; Tao Xi; Jianping Ruan; Kristina Xiao Liang; Ruizhe Huang
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Stem cell derived astrocytes withPOLGmutations and mitochondrial dysfunction including abnormal NAD+ metabolism is toxic for neurons

2020-12-22 | Preprint
Contributors: Kristina Xiao Liang; Atefeh Kianian; Anbin Chen; Cecilie Katrin Kristiansen; Yu Hong; Jessica Furriol; Lena Elise Høyland; Mathias Ziegler; Torbjørn Kråkenes; Charalampos Tzoulis et al.
Source: check_circle
Crossref

N-acetylcysteine amide ameliorates mitochondrial dysfunction and reduces oxidative stress in hiPSC-derived dopaminergic neurons with POLG mutation.

Experimental neurology
2020-11-29 | Journal article
Source: Self-asserted source
Kristina Xiao Liang
grade
Preferred source (of 3)‎

A method for differentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96-well microplates.

Scientific reports
2020-10-28 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

Disease‐specific phenotypes in iPSC ‐derived neural stem cells with POLG mutations

EMBO Molecular Medicine
2020-10-07 | Journal article
Contributors: Kristina Xiao Liang; Cecilie Katrin Kristiansen; Sepideh Mostafavi; Guro Helén Vatne; Gina Alien Zantingh; Atefeh Kianian; Charalampos Tzoulis; Lena Elise Høyland; Mathias Ziegler; Roberto Megias Perez et al.
Source: check_circle
Crossref

AChR antibodies show a complex interaction with human skeletal muscle cells in a transcriptomic study.

Scientific reports
2020-07-08 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma.

Cell death & disease
2020-06-25 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

Patient-specific neural progenitor cells derived from induced pluripotent stem cells offer a promise of good models for mitochondrial disease

Cell and Tissue Research
2020-04 | Journal article
Contributors: Xiao Liang; Cecilie Katrin Kristiansen; Guro Helén Vatne; Yu Hong; Laurence Albert Bindoff
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

CircCDR1as upregulates autophagy under hypoxia to promote tumor cell survival via AKT/ERK½/mTOR signaling pathways in oral squamous cell carcinomas.

Cell death & disease
2019-10-03 | Journal article
Source: Self-asserted source
Kristina Xiao Liang
grade
Preferred source (of 2)‎

Isolation and characterization of cells derived from human epithelial rests of Malassez

Odontology
2019-07 | Journal article
Part of ISSN: 1618-1247
Part of ISSN: 1618-1255
Source: Self-asserted source
Kristina Xiao Liang

Metabolic reprogramming of normal oral fibroblasts correlated with increased glycolytic metabolism of oral squamous cell carcinoma and precedes their activation into carcinoma associated fibroblasts.

Cellular and molecular life sciences : CMLS
2019-07-03 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

Fibroblasts rescue oral squamous cancer cell from metformin-induced apoptosis via alleviating metabolic disbalance and inhibiting AMPK pathway.

Cell cycle (Georgetown, Tex.)
2019-04-23 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

Suppression of OSCC malignancy by oral glands derived-PIP identified by iTRAQ combined with 2D LC-MS/MS.

Journal of cellular physiology
2019-01-28 | Journal article
Source: Self-asserted source
Kristina Xiao Liang
grade
Preferred source (of 2)‎

Prevalence of dentin hypersensitivity among the residents of Xi'an city, China.

Acta odontologica Scandinavica
2017-05-13 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma.

EBioMedicine
2016-01-09 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

Human oral cancer cells with increasing tumorigenic abilities exhibit higher effective membrane capacitance

Integr. Biol.
2014 | Journal article
Part of ISSN: 1757-9694
Part of ISSN: 1757-9708
Source: Self-asserted source
Kristina Xiao Liang
grade
Preferred source (of 2)‎

Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.

European journal of cancer (Oxford, England : 1990)
2014-10-10 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma.

Journal of translational medicine
2014-10-04 | Journal article
Source: Self-asserted source
Kristina Xiao Liang
grade
Preferred source (of 2)‎

Abstract 2021: A novel model to study the stroma-induced drug resistance in glioblastoma cells

Cancer Research
2014-10-01 | Journal article
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Contributors: Ning Yang; Huaiyang Zhu; Tao Yan; Xiao Liang; Lina Wik Leiss; Per Øyvind Enger; Xingang Li; Jian Wang
Source: Self-asserted source
Kristina Xiao Liang

Biological Characteristics of Stem- Like Cells in Oral Squamous Cell Carcinoma

2013-06-18 | Dissertation or Thesis
Source: Self-asserted source
Kristina Xiao Liang

Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative.

Cancer research
2011-06-17 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

Rapid detection of oral cancer: Electrophysiological characterization by eielectrophoresis technology.

Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy-Technical Proceedings of the 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010
2010 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

Rapid detection of oral cancer: Electrophysiological characterization by dielectrophoresis technology.

Nanotechnology 2010,Bio Sensors, Instruments, Medical, Environment and Energy - Technical Proceedings of the 2010 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2010
2010-06 | Journal article
Contributors: Kristina Xiao Liang
Source: Self-asserted source
Kristina Xiao Liang

A multi-centre and cross-sectional study of dentine hypersensitivity in China.

Journal of clinical periodontology
2009-12-21 | Journal article
Source: Self-asserted source
Kristina Xiao Liang

A novel model to study the stroma-induced drug resistance in glioblastoma cells

Cancer Research 74 (19 Supplement), 2021-2021
Journal article
Source: Self-asserted source
Kristina Xiao Liang

Ferroptosis Holds Novel Promise in Treatment of Cancer Mediated by Non-coding RNAs

Frontiers in Cell and Developmental Biology, section Molecular and Cellular Oncology
Journal article
Source: Self-asserted source
Kristina Xiao Liang

Peer review (8 reviews for 6 publications/grants)

Review activity for Advanced science. (1)
Review activity for Cellular & Molecular Biology Letters. (1)
Review activity for iScience. (3)
Review activity for Molecular therapy. (1)
Review activity for Nature communications (1)
Review activity for Stem cell reviews. (1)