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Scopus Author ID: 56053270500

Keywords

Biochemistry, Kinetic of Enzymes, Chemistry of protein, Chromatography

Countries

Türkiye

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Employment (3)

Erzincan Binali Yıldırım Üniversitesi: Erzincan, Erzincan, TR

2019-08-26 to present | Associate Professor (Basic Pharmaceutical Science)
Employment
Source: Self-asserted source
Esra Dilek

Erzincan University: Erzincan, TR

2013-03-12 to present | Assistant Professor (basic pharmaceutical science)
Employment
Source: Self-asserted source
Esra Dilek

Atatürk University: Erzurum, TR

2007-03-08 to 2013-03-08 | Research Assistant (Chemistry)
Employment
Source: Self-asserted source
Esra Dilek

Education and qualifications (1)

Atatürk University: Erzurum, TR

2005-09-10 to 2012-06-12 | Doctor's degree (Chemistry)
Education
Source: Self-asserted source
Esra Dilek

Works (31)

Assessing indole derivative molecules as dual acetylcholinesterase and butyrylcholinesterase inhibitors through In Vitro inhibition and molecular modelling studies

Journal of Molecular Structure
2024-09 | Journal article
DOI: 10.1016/j.molstruc.2024.138276
Part of ISSN: 0022-2860
Contributors: zuhal alım; Hanif Şirinzade; Namık Kılınç; Esra Dilek; Sibel Süzen
Source: Self-asserted source
Esra Dilek

Exploring New 5‐Nitroimidazole Derivatives As Potent Acetylcholinesterase and Butyrylcholinesterase Enzyme Inhibitors

Chemistry & Biodiversity
2024-09-13 | Journal article | Author
DOI: 10.1002/cbdv.202400918
Part of ISSN: 1612-1872
Part of ISSN: 1612-1880
Contributors: ŞULE GÜRSOY; Doruk Satici; Burak Kuzu; Burcin Turkmenoglu; Esra Dilek; Oztekin Algul
Source: Self-asserted source
Esra Dilek

Exploring Novel Schiff Base Compounds Derived from Benzothiophene-3- carboxaldehyde Hydrazones: In vitro and In silico Evaluation as Potential Inhibitors of Cholinesterases and Carbonic Anhydrases I-II

Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi
2024-03-28 | Journal article | Author
DOI: 10.18185/erzifbed.1377310
Part of ISSN: 2149-4584
Contributors: ŞULE GÜRSOY; Zeynep ÇAKA; Nagihan Faydalı; Hanif Sirinzade; Esra Dilek
Source: Self-asserted source
Esra Dilek
grade
Preferred source (of 2)‎

Hydrazide‐Bridged Pyridazines for Cholinesterase Inhibitors: Synthesis, Characterizations, In Silico, and In Vitro Evaluation

ChemistrySelect
2024-03-26 | Journal article
DOI: 10.1002/slct.202400085
Part of ISSN: 2365-6549
Part of ISSN: 2365-6549
Contributors: ŞULE GÜRSOY; Gulce Taskor Onel; Burcin Turkmenoglu; Irem Bozbey Merde; Esra Dilek; ceylan hepokur; OZTEKIN ALGUL
Source: Self-asserted source
Esra Dilek

Enzyme inhibitory potential of some indole Schiff bases on acetylcholinesterase and human carbonic anhydrase isoforms I and II enzymes: an <i>in vitro and</i> molecular docking study

Journal of Biomolecular Structure and Dynamics
2023-10-20 | Journal article | Author
DOI: 10.1080/07391102.2023.2266500
Part of ISSN: 0739-1102
Part of ISSN: 1538-0254
Contributors: Ebru Akman; Hanif Sirinzade; Serap Yilmaz Ozguven; Esra Dilek; Sibel Suzen
Source: Self-asserted source
Esra Dilek

Evaluation of Naphthalenylmethylen Hydrazine Derivatives as Potent Inhibitors on, Antiatherogenic Enzymes, Paraoxonase I and Acetylcholinesterase Activities

ChemistrySelect
2022 | Journal article
DOI: 10.1002/slct.202104489
EID:

2-s2.0-85128069293

Part of ISSN: 23656549
Contributors: Shirinzadeh, H.; Dilek, E.; Alım, Z.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Inhibitory effects of novel 3(2H)pyridazinone-triazole derivatives against acetylcholinesterase enzyme

Journal of Research in Pharmacy
2022 | Journal article
DOI: 10.29228/jrp.239
Part of ISSN: 2630-6344
Contributors: İrem Bozbey; Gülce Taşkor Önel; Burçin Türkmenoğlu; Şule Gürsoy; Esra Dilek; Muhammed Ergün; Azime Berna Özçelik; Mehtap Uysal
Source: Self-asserted source
Esra Dilek
grade
Preferred source (of 4)‎

Pyridazinones containing the (4-methoxyphenyl)piperazine moiety as AChE/BChE inhibitors: design, synthesis, in silico and biological evaluation

Medicinal Chemistry Research
2022-11 | Journal article
DOI: 10.1007/s00044-022-02968-x
Part of ISSN: 1054-2523
Part of ISSN: 1554-8120
Contributors: İrem Bozbey Merde; Gülce T. Önel; Burçin Türkmenoğlu; Şule Gürsoy; Esra Dilek
Source: Self-asserted source
Esra Dilek

(<i>p</i>‐Chlorophenyl)‐3(2<i>H</i>)pyridazinone Derivatives: Synthesis, <i>in Silico</i>, and AChE/BChE Inhibitory Activity

ChemistrySelect
2022-10-13 | Journal article
DOI: 10.1002/slct.202202446
Part of ISSN: 2365-6549
Part of ISSN: 2365-6549
Contributors: İrem Bozbey Merde; Gülce Taşkor Önel; Burçin Türkmenoğlu; Şule Gürsoy; Esra Dilek
Source: Self-asserted source
Esra Dilek

Novel (p-tolyl)-3(2H)-pyridazinone derivatives containing substituted-1,2,3-triazole moiety as new anti-Alzheimer agents: Synthesis, in vitro and in silico assays

Fabad Journal of Pharmaceutical Sciences
2022-08-04 | Journal article
DOI: 10.55262/fabadeczacilik.1128446
Part of ISSN: 1300-4182
Contributors: İrem BOZBEY; Gülce TAŞKOR ÖNEL; Burçin TÜRKMENOĞLU; Şule GÜRSOY; Esra DİLEK
Source: Self-asserted source
Esra Dilek
grade
Preferred source (of 2)‎

Synthesis of (<i>p‐</i>tolyl)‐3(2<i>H</i>)pyridazinone Derivatives as Novel Acetylcholinesterase Inhibitors

ChemistrySelect
2022-07-27 | Journal article | Author
DOI: 10.1002/slct.202201606
Part of ISSN: 2365-6549
Part of ISSN: 2365-6549
Contributors: İrem Bozbey Merde; Gülce Taşkor Önel; Burçin Türkmenoğlu; ŞULE GÜRSOY; Esra Dilek; Azime Berna Özçelik; Mehtap Uysal
Source: Self-asserted source
Esra Dilek

The paraoxonase 1 activity and lipid levels in umbilical cord blood and maternal venous blood, and their relations according to birth weight

The European Research Journal
2022-01-04 | Journal article | Author
DOI: 10.18621/eurj.869966
Part of ISSN: 2149-3189
Contributors: Berrin Göktuğ Kadıoğlu; Aysel Nalçakan Ergünay; Esra Dilek
Source: Self-asserted source
Esra Dilek

Relationship between zinc content and carbonic anhydrase activity in blood of anemic pregnant women in Turkey

Journal of Obstetrics and Gynaecology Research
2020 | Journal article
DOI: 10.1111/jog.14506
EID:

2-s2.0-85091614749

Part of ISSN: 14470756 13418076
Contributors: Göktuğ Kadıoğlu, B.; Nalçakan, A.; Dilek, E.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Synthesis, characterization and biological activity evaluation of novel naphthalenylmethylen hydrazine derivatives as carbonic anhydrase inhibitors

Journal of Molecular Structure
2020 | Journal article
DOI: 10.1016/j.molstruc.2020.128657
EID:

2-s2.0-85086509133

Part of ISSN: 00222860
Contributors: Shirinzadeh, H.; Dilek, E.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Antibiotics used in patients after surgery and effects of human serum paraoxonase-i (PON1) enzyme activity

Protein and Peptide Letters
2019 | Journal article
DOI: 10.2174/0929866526666190124144622
EID:

2-s2.0-85064113124

Part of ISSN: 18755305 09298665
Contributors: Yilmaz, A.; Dilek, E.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Synthesis, characterization, and in vitro effect of the Cu(II) complex with niflumic acid and 3-picoline on paraoxanase-I

Archiv der Pharmazie
2019 | Journal article
DOI: 10.1002/ardp.201900007
EID:

2-s2.0-85066306455

Part of ISSN: 15214184 03656233
Contributors: Dilek, E.; Caglar, S.; Çardak, S.; Karakoç, B.; Caglar, B.; Sahin, O.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Antibiyotik Olarak Kullanılan Sultamisilin, Sefdinir, Vankomisin Hidroklorür ve Kolistin Etken Maddelerinin İnsan Serum Paraoksonaz1 Enzim Aktivitesi Üzerine in vitro Etkilerinin İncelenmesi

Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi
2019-03-24 | Journal article | Author
DOI: 10.18185/erzifbed.467627
Part of ISSN: 2149-4584
Contributors: Esra Dilek; Merve Berivan ÖZÇELİK; Serhat YILDIRIM
Source: Self-asserted source
Esra Dilek

Synthesis and characterization of four novel palladium(II) and platinum(II) complexes with 1-(2-aminoethyl)pyrrolidine, diclofenac and mefenamic acid: In vitro effect of these complexes on human serum paraoxanase1 activity

Journal of Biochemical and Molecular Toxicology
2018 | Journal article
DOI: 10.1002/jbt.22043
EID:

2-s2.0-85043341903

Part of ISSN: 10990461 10956670
Contributors: Dilek, E.; Caglar, S.; Erdogan, K.; Caglar, B.; Sahin, O.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Activation of two different drugs used in alzheimer’s disease treatment on human carbonic anhydrase isozymes I and II activity: An in vitro study,Alzheimer hastalığının tedavisinde kullanılan iki farklı ilacın insan karbonik anhidraz I ve II izoenzim aktiviteleri üzerindeki aktivasyonu: İn vitro çalışma

Turkish Journal of Pharmaceutical Sciences
2017 | Journal article
DOI: 10.4274/tjps.43434
EID:

2-s2.0-85026674402

Part of ISSN: 1304530X
Contributors: Dilek, E.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Investigation on the effects of pomiferin from Maclura pomifera on indomethacin-induced gastric ulcer: An experimental study in rats

Medicinal Chemistry Research
2017 | Journal article
DOI: 10.1007/s00044-017-1913-y
EID:

2-s2.0-85019200222

Part of ISSN: 15548120 10542523
Contributors: Bozkurt, İ.; Dilek, E.; Erol, H.S.; Çakir, A.; Hamzaoğlu, E.; Koç, M.; Keleş, O.N.; Halici, M.B.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Natural product inhibitors of carbonic anhydrase I and II isoenzymes: osajin and pomiferin

Archives of Physiology and Biochemistry
2017 | Journal article
DOI: 10.1080/13813455.2017.1303742
EID:

2-s2.0-85016190188

Part of ISSN: 17444160 13813455
Contributors: Dilek, E.; Erol, H.S.; Cakir, A.; Koc, M.; Halici, M.B.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Synthesis, crystal structure, spectroscopy, thermal properties and carbonic anhydrase activities of new metal(II) complexes with mefenamic acid and picoline derivatives

Journal of Coordination Chemistry
2017 | Journal article
DOI: 10.1080/00958972.2017.1366996
EID:

2-s2.0-85028539012

Part of ISSN: 10290389 00958972
Contributors: Dilek, E.; Caglar, S.; Dogancay, N.; Caglar, B.; Sahin, O.; Tabak, A.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Alzheimer Hastalığı Tedavisinde Kullanılan Rivastigmin ve Galantamin İlaç Etken Maddelerinin CA I ve II İzoenzimleri Üzerine in vitro Etkilerinin İncelenmesi

2017-10 | Journal article
Contributors: Murat ÇANKAYA; Talat EZMECİ; Mukadder SUNAR; T. Abdulkadir ÇOBAN
Source: Self-asserted source
Esra Dilek

Investigation Effects of Some Heart Disorder Drugs on Human Carbonic Anhydrase I

Hacettepe Journal of Biology and Chemistry
2017-04-01 | Journal article
DOI: 10.15671/hjbc.2017.156
Part of ISSN: 1303-5002
Contributors: Sibel Tuğral Kaplan; Mehmet Kuzucu; Nurdagül Aktaş; Esra Dilek; Murat Çankaya
Source: Self-asserted source
Esra Dilek

In vitro inhibition of three different drugs used in rheumatoid arthritis treatment on human serum paraoxanase 1 enzyme activity

Protein and Peptide Letters
2016 | Journal article
DOI: 10.2174/0929866522666151013130102
EID:

2-s2.0-84953708025

Part of ISSN: 18755305 09298665
Contributors: Dileka, E.; Polat, M.F.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

New copper(II) complexes including pyridine-2,5-dicarboxylic acid: synthesis, spectroscopic, thermal properties, crystal structure and how these complexes interact with purified PON 1 enzyme

Journal of Coordination Chemistry
2016 | Journal article
DOI: 10.1080/00958972.2016.1188295
EID:

2-s2.0-84971483699

Part of ISSN: 10290389 00958972
Contributors: Caglar, S.; Dilek, E.; Hamamci Alisir, S.; Caglar, B.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

New metal complexes with diclofenac containing 2-pyridineethanol or 2-pyridinepropanol: synthesis, structural, spectroscopic, thermal properties, catechol oxidase and carbonic anhydrase activities

Journal of Coordination Chemistry
2016 | Journal article
DOI: 10.1080/00958972.2016.1227802
EID:

2-s2.0-84991069458

Part of ISSN: 10290389 00958972
Contributors: Caglar, S.; Dilek, E.; Caglar, B.; Adiguzel, E.; Temel, E.; Buyukgungor, O.; Tabak, A.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

Synthesis of two phloroglucinol derivatives with cinnamyl moieties as inhibitors of the carbonic anhydrase isozymes I and II: an in vitro study

Journal of Enzyme Inhibition and Medicinal Chemistry
2016 | Journal article
DOI: 10.1080/14756366.2016.1181626
EID:

2-s2.0-84967224362

Part of ISSN: 14756374 14756366
Contributors: Burmaoğlu, S.; Dilek, E.; Yılmaz, A.O.; Supuran, C.T.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

International Journal of Pharmaceutical Chemistry

2015-06 | Journal article
DOI: 10.7439/ijpc
Part of ISSN: 2249-734X
Source: Self-asserted source
Esra Dilek

Impacts of some antibiotics on human serum paraoxonase 1 activity

Journal of Enzyme Inhibition and Medicinal Chemistry
2013 | Journal article
DOI: 10.3109/14756366.2012.681653
EID:

2-s2.0-84880068282

Part of ISSN: 14756366 14756374
Contributors: Dilek, E.B.; Küfrevioǧlu, Ö.I.; Beydemir, Ş.
Source: Self-asserted source
Esra Dilek via Scopus - Elsevier

In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II

Bioorganic &amp; Medicinal Chemistry
2008-10 | Journal article | Investigation
DOI: 10.1016/j.bmc.2008.09.028
Part of ISSN: 0968-0896
Contributors: Esra Dilek
Source: Self-asserted source
Esra Dilek

Peer review (15 reviews for 6 publications/grants)

Review activity for Chemické zvesti. (1)
Review activity for ChemistrySelect (5)
Review activity for Expert opinion on drug metabolism and toxicology (1)
Review activity for Journal of biomolecular structure and dynamics. (2)
Review activity for Medicinal chemistry research. (4)
Review activity for South African journal of botany. (2)
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