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autism, epidemiology, causal inference
United States

Biography

Dr. Lee received his PhD and MHS degrees in Epidemiology from The Johns Hopkins University, and graduated Cum laude with an AB in Biological Anthropology from Harvard College. His research interests include the epidemiology of neurological development, maintenance and decline. Current topics include prenatal environmental exposures and autism risk; neighborhoods and psychosocial "stress" in the cognitive decline of older adults; lead toxicity and white matter health; gene-environment interaction; maternal antibody exposure in utero and fetal outcomes. In addition to his etiological research, Dr. Lee is interested in epidemiological methods including causal inference methodology, data mining and machine learning algorithms, and automated data extraction techniques for structured and unstructured data.

Activities

Employment (3)

Karolinska Institutet: Stockholm, SE

(Department of Medical Epidemiology and Biostatistics)
Employment
Source: check_circle
Karolinska Institutet

Karolinska Institutet: Stockholm, SE

(Department of Public Health Sciences)
Employment
Source: check_circle
Karolinska Institutet

Drexel University School of Public Health: Philadelphia, PA, US

2009 to present | Associate Professor (Epidemiology and Biostatistics)
Employment
Source: Self-asserted source
Brian Lee

Education and qualifications (2)

Johns Hopkins University: Baltimore, MD, US

2004 to 2009 | PhD (Epidemiology)
Education
Source: Self-asserted source
Brian Lee

Harvard University: Cambridge, MA, US

1999 to 2003 | AB (Anthropology)
Education
Source: Self-asserted source
Brian Lee

Funding (4)

Early life vitamin D levels and risk of autism spectrum disorders

2014-08-20 to 2016-07-31 | Grant
National Institute of Environmental Health Sciences (Bethesda, US)
GRANT_NUMBER: 5R21ES023760-02
GRANT_NUMBER: 5R21ES023760-02
Source: Self-asserted source
Brian Lee via DimensionsWizard

Risk Profiling of Pregnant Women for Targeted Screening for Alloimmunization

2013-01-01 to 2016-12-31 | Grant
Swedish Research Council (n/a, SE)
GRANT_NUMBER: 2012-3206
GRANT_NUMBER: 2012-3206
Source: Self-asserted source
Brian Lee via DimensionsWizard

The role of early life inflammation in the aethiology of autism spectrum disorder: a longitudinal study based on a combination of register and bio-sample data.

2013-01-01 to 2016-12-31 | Grant
Swedish Research Council (n/a, SE)
GRANT_NUMBER: 2012-2264
GRANT_NUMBER: 2012-2264
Source: Self-asserted source
Brian Lee via DimensionsWizard

Use of Selective Serotonin Reuptake Inhibitors in Pregnancy and Offspring Neurodevelopment

2013-01-01 to 2015-12-31 | Grant
Swedish Research Council (n/a, SE)
GRANT_NUMBER: 2012-3017
GRANT_NUMBER: 2012-3017
Source: Self-asserted source
Brian Lee via DimensionsWizard

Works (50 of 53)

Items per page:
Page 1 of 2

Psychotropic Medication Use in Children and Youth with Autism Enrolled in Medicaid

Journal of Autism and Developmental Disorders
2025-01 | Journal article
Contributors: Jessica E. Rast; Sha Tao; Whitney Schott; Lindsay L. Shea; Edward S. Brodkin; Connor M. Kerns; Charles E. Leonard; Michael J. Murray; Brian K. Lee
Source: check_circle
Crossref

First trimester antidepressant use and miscarriage: a comprehensive analysis in the UK Clinical Practice Research Datalink

2024-10-21 | Preprint
Contributors: Florence Zoe Martin; Paul Madley-Dowd; Viktor H Ahlqvist; Gemma C Sharp; Kayleigh E Easey; Brian K Lee; Abi Merriel; Dheeraj Rai; Harriet Forbes
Source: check_circle
Crossref

Self-Reported COVID-19 Vaccine and Booster Acceptance and Hesitancy Among Autistic Adults in Pennsylvania: Cross-Sectional Analysis of Survey Data

JMIR Public Health and Surveillance
2024-08-28 | Journal article
Contributors: Lindsay Shea; Dylan Cooper; Jonas Ventimiglia; Shelby Frisbie; Conner Carlton; Wei Song; Mark Salzer; Brian Lee; Emily Hotez; David J Vanness
Source: check_circle
Crossref

Contrasting methods to operationalize antibiotic exposure in clinical research: a real-world application on health care–associated Clostridioides difficile infection

American Journal of Epidemiology
2024-08-27 | Journal article
Contributors: Jessica L Webster; Stephen Eppes; Brian K Lee; Nicole S Harrington; Neal D Goldstein
Source: check_circle
Crossref

Maternal intrahepatic cholestasis of pregnancy and neurodevelopmental conditions in offspring: A population-based cohort study of 2 million Swedish children

PLOS Medicine
2024-01-16 | Journal article
Contributors: Shuyun Chen; Gordon C. Smith; Viktor H. Ahlqvist; Hugo Sjöqvist; Olof Stephansson; Cecilia Magnusson; Christina Dalman; Håkan Karlsson; Brian K. Lee; Renee M. Gardner
Source: check_circle
Crossref

Big data in autism research: Methodological challenges and solutions

Autism Research
2023-10 | Journal article
Contributors: Brian K. Lee; Diana E. Schendel; Lindsay L. Shea
Source: check_circle
Crossref

Self-Reported COVID-19 Vaccine and Booster Acceptance and Hesitancy Among Autistic Adults in Pennsylvania: Cross-Sectional Analysis of Survey Data (Preprint)

2023-07-19 | Preprint
Contributors: Lindsay Shea; Dylan Cooper; Jonas Ventimiglia; Shelby Frisbie; Conner Carlton; Wei Song; Mark Salzer; Brian Lee; Emily Hotez; David J Vanness
Source: check_circle
Crossref

Bias amplification of unobserved confounding in pharmacoepidemiological studies using indication-based sampling: there is no free lunch in restricting the sample to those with a particular drug-indication

2022-02-08 | Preprint
Contributors: Viktor H. Ahlqvist; Paul Madley-Dowd; Amanda Ly; Jessica Rast; Michael Lundberg; Egill Jónsson-Bachmann; Daniel Berglind; Dheeraj Rai; Cecilia Magnusson; Brian K. Lee
Source: check_circle
Crossref

Developmental vitamin D and autism spectrum disorders: findings from the Stockholm Youth Cohort

Molecular Psychiatry
2021-05-06 | Journal article
Contributors: Brian K. Lee; Darryl W. Eyles; Cecilia Magnusson; Craig J. Newschaffer; John J. McGrath; David Kvaskoff; Pauline Ko; Christina Dalman; Håkan Karlsson; Renee M. Gardner
Source: check_circle
Crossref

Birth seasonality and risk of autism spectrum disorder

European Journal of Epidemiology
2019-08-20 | Journal article
Contributors: Brian K. Lee; Raz Gross; Richard W. Francis; Håkan Karlsson; Diana E. Schendel; Andre Sourander; Abraham Reichenberg; Erik T. Parner; Mady Hornig; Amit Yaniv et al.
Source: check_circle
Crossref

Parent‐reported prevalence of food allergies in children with autism spectrum disorder: National health interview survey, 2011–2015

Autism Research
2019-05 | Journal article
Contributors: Yuling Tan; Shiny Thomas; Brian K. Lee
Source: check_circle
Crossref

Maternal hirsutism and autism spectrum disorders in offspring

Autism Research
2017-09 | Journal article
Contributors: Brian K. Lee; Stefan Arver; Linnea Widman; Renee M. Gardner; Cecilia Magnusson; Christina Dalman; Kyriaki Kosidou
Source: check_circle
Crossref

Prevalence of Autism Spectrum Disorders with and without Intellectual Disability by Gestational Age at Birth in the Stockholm Youth Cohort: a Register Linkage Study.

Paediatric and perinatal epidemiology
2017-09 | Journal article
Source: Self-asserted source
Brian Lee via Europe PubMed Central

Antidepressants during pregnancy and autism in offspring: population based cohort study.

BMJ : British Medical Journal
2017-07 | Journal article
Source: Self-asserted source
Brian Lee via Europe PubMed Central

Presence of an epigenetic signature of prenatal cigarette smoke exposure in childhood.

2015-11 | Journal article
Contributors: Ladd-Acosta C; Shu C; Lee BK; Gidaya N; Singer A; Schieve LA; Schendel DE; Jones N; Daniels JL; Windham GC et al.
Source: Self-asserted source
Brian Lee via Europe PubMed Central

Maternal folate status as a risk factor for autism spectrum disorders: a review of existing evidence.

2015-09 | Journal article
Contributors: DeVilbiss EA; Gardner RM; Newschaffer CJ; Lee BK
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Occupational physical demand and risk of hip fracture in older women.

2015-08 | Journal article
Contributors: Palumbo AJ; Michael YL; Burstyn I; Lee BK; Wallace R
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Changes in prevalence of autism spectrum disorders in 2001-2011: findings from the Stockholm youth cohort.

2015-06 | Journal article
Contributors: Idring S; Lundberg M; Sturm H; Dalman C; Gumpert C; Rai D; Lee BK; Magnusson C
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Maternal body mass index during early pregnancy, gestational weight gain, and risk of autism spectrum disorders: Results from a Swedish total population and discordant sibling study.

2015-06 | Journal article
Contributors: Gardner RM; Lee BK; Magnusson C; Rai D; Frisell T; Karlsson H; Idring S; Dalman C
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Maternal Smoking and Autism Spectrum Disorder: A Meta-analysis.

2015-06 | Journal article
Contributors: Rosen BN; Lee BK; Lee NL; Yang Y; Burstyn I
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Advancing parental age and autism: multifactorial pathways.

2015-02 | Journal article
Contributors: Lee BK; McGrath JJ
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Use of meconium in perinatal epidemiology: potential benefits and pitfalls.

2014-12 | Journal article
Contributors: Park BY; Lee BK
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Hospital Admission With Infection During Childhood and Risk for Psychotic Illness-A Population-based Cohort Study.

2014-11 | Journal article
DOI:

10.1093/schbul/sbt195

PMID:

24366719

Contributors: Blomström A; Karlsson H; Svensson A; Frisell T; Lee BK; Dal H; Magnusson C; Dalman C
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

In utero exposure to selective serotonin reuptake inhibitors and risk for autism spectrum disorder.

2014-10 | Journal article
DOI:

10.1007/s10803-014-2128-4

PMID:

24803368

Contributors: Gidaya NB; Lee BK; Burstyn I; Yudell M; Mortensen EL; Newschaffer CJ
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Knowledge and attitudes about Parkinson's disease among a diverse group of older adults.

2014-09 | Journal article
DOI:

10.1007/s10823-014-9233-x

PMID:

24752756

Contributors: Pan S; Stutzbach J; Reichwein S; Lee BK; Dahodwala N
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders.

2014-09 | Journal article
DOI:

10.1016/j.bbi.2014.09.001

PMID:

25218900

Contributors: Lee BK; Magnusson C; Gardner RM; Blomström A; Newschaffer CJ; Burstyn I; Karlsson H; Dalman C
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Associations of Rhesus and non-Rhesus maternal red blood cell alloimmunization with stillbirth and preterm birth.

2014-08 | Journal article
DOI:

10.1093/ije/dyu079

PMID:

24801308

Contributors: Fan J; Lee BK; Wikman AT; Johansson S; Reilly M
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Residential proximity to electromagnetic field sources and birth weight: Minimizing residual confounding using multiple imputation and propensity score matching.

2014-08 | Journal article
DOI:

10.1016/j.envint.2014.04.012

PMID:

24815339

Contributors: de Vocht F; Lee B
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Caregiving Frequency and Physical Function: The Women's Health Initiative.

2014-07 | Journal article
DOI:

10.1093/gerona/glu104

PMID:

25060315

Contributors: Rosso AL; Lee BK; Stefanick ML; Kroenke CH; Coker LH; Woods NF; Michael YL
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Brief Report: Trends in U.S. National Autism Awareness from 2004 to 2014: The Impact of National Autism Awareness Month.

2014-06 | Journal article
DOI:

10.1007/s10803-014-2160-4

PMID:

24915931

Contributors: DeVilbiss EA; Lee BK
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Mapping Collaboration Networks in the World of Autism Research.

2014-05 | Journal article
DOI:

10.1002/aur.1393

PMID:

24850670

Contributors: Goldstein ND; Tager-Flusberg H; Lee BK
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

School performance and the risk of suicide attempts in young adults: a longitudinal population-based study.

2014-04 | Journal article
DOI:

10.1017/S0033291713001852

PMID:

23883735

Contributors: Kosidou K; Dalman C; Fredlund P; Lee BK; Galanti R; Isacsson G; Magnusson C
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

A no-cost geocoding strategy using R.

2014-03 | Journal article
DOI:

10.1097/EDE.0000000000000052

PMID:

24487219

Contributors: Goldstein ND; Auchincloss AH; Lee BK
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Parental age and the risk of autism spectrum disorders: findings from a Swedish population-based cohort.

2014-02 | Journal article
DOI:

10.1093/ije/dyt262

PMID:

24408971

Contributors: Idring S; Magnusson C; Lundberg M; Ek M; Rai D; Svensson AC; Dalman C; Karlsson H; Lee BK
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Neonatal levels of acute phase proteins and later risk of non-affective psychosis.

2013 | Journal article
DOI:

10.1038/tp.2013.5

PMID:

23423137

PMC:

PMC3591005

Contributors: Gardner RM; Dalman C; Wicks S; Lee BK; Karlsson H
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study.

2013 | Journal article
DOI:

10.1136/bmj.f2059

PMID:

23604083

PMC:

PMC3630989

Contributors: Rai D; Lee BK; Dalman C; Golding J; Lewis G; Magnusson C
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Total blood mercury levels and depression among adults in the United States: National Health and Nutrition Examination Survey 2005-2008.

2013 | Journal article
DOI:

10.1371/journal.pone.0079339

PMID:

24244482

PMC:

PMC3823698

Contributors: Ng TH; Mossey JM; Lee BK
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Prognostic score-based balance measures can be a useful diagnostic for propensity score methods in comparative effectiveness research.

2013-08 | Journal article
DOI:

10.1016/j.jclinepi.2013.01.013

PMID:

23849158

PMC:

PMC3713509

Contributors: Stuart EA; Lee BK; Leacy FP
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Serum folate but not vitamin B-12 concentrations are positively associated with cognitive test scores in children aged 6-16 years.

2013-04 | Journal article
DOI:

10.3945/jn.112.166165

PMID:

23390191

Contributors: Nguyen CT; Gracely EJ; Lee BK
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Autism spectrum disorders in the Stockholm Youth Cohort: design, prevalence and validity.

2012 | Journal article
DOI:

10.1371/journal.pone.0041280

PMID:

22911770

PMC:

PMC3401114

Contributors: Idring S; Rai D; Dal H; Dalman C; Sturm H; Zander E; Lee BK; Serlachius E; Magnusson C
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Presentation of study results: the authors' responsibility

Environ. Health Perspect.
2012 | Journal article
SOURCE-WORK-ID:

125463234

Contributors: Burstyn, I; Lee, B; Gidaya, NB; Yudell, M
Source: check_circle
Karolinska Institutet

Joint effects of obesity and vitamin D insufficiency on insulin resistance and type 2 diabetes: results from the NHANES 2001-2006.

2012-10 | Journal article
DOI:

10.2337/dc12-0235

PMID:

22751957

PMC:

PMC3447853

Contributors: Kabadi SM; Lee BK; Liu L
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

ABO and RhD blood groups and gestational hypertensive disorders: a population-based cohort study.

2012-09 | Journal article
DOI:

10.1111/j.1471-0528.2012.03421.x

PMID:

22734590

Contributors: Lee BK; Zhang Z; Wikman A; Lindqvist PG; Reilly M
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Brief report: maternal smoking during pregnancy and autism spectrum disorders.

2012-09 | Journal article
DOI:

10.1007/s10803-011-1425-4

PMID:

22173844

Contributors: Lee BK; Gardner RM; Dal H; Svensson A; Galanti MR; Rai D; Dalman C; Magnusson C
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Constructing a population-based research database from routine maternal screening records: a resource for studying alloimmunization in pregnant women.

2011 | Journal article
Contributors: Lee BK; Ploner A; Zhang Z; Gryfelt G; Wikman A; Reilly M
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Weight trimming and propensity score weighting.

2011 | Journal article
DOI:

10.1371/journal.pone.0018174

PMID:

21483818

PMC:

PMC3069059

Contributors: Lee BK; Lessler J; Stuart EA
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Neighborhood psychosocial environment, apolipoprotein E genotype, and cognitive function in older adults.

2011-03 | Journal article
DOI:

10.1001/archgenpsychiatry.2011.6

PMID:

21383266

PMC:

PMC3328419

Contributors: Lee BK; Glass TA; James BD; Bandeen-Roche K; Schwartz BS
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Epidemiologic research and Web 2.0--the user-driven Web.

2010-11 | Journal article
DOI:

10.1097/EDE.0b013e3181f5a75f

PMID:

20924229

Contributors: Lee BK
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Improving propensity score weighting using machine learning.

2010-02 | Journal article
DOI:

10.1002/sim.3782

PMID:

19960510

PMC:

PMC2807890

Contributors: Lee BK; Lessler J; Stuart EA
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎

Apolipoprotein e genotype, cortisol, and cognitive function in community-dwelling older adults.

2008-11 | Journal article
DOI:

10.1176/appi.ajp.2008.07091532

PMID:

18593777

PMC:

PMC2579316

Contributors: Lee BK; Glass TA; Wand GS; McAtee MJ; Bandeen-Roche K; Bolla KI; Schwartz BS
Source: Self-asserted source
Brian Lee via Europe PubMed Central
grade
Preferred source (of 2)‎
Items per page:
Page 1 of 2

Peer review (4 reviews for 4 publications/grants)

Review activity for Communications medicine. (1)
Review activity for Global epidemiology. (1)
Review activity for Nature communications (1)
Review activity for PLoS medicine. (1)