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Works (45)

Target-Triggered Cascaded Self-Feedback DNAzyme Circuit Loaded in ZIF-8 for Highly Sensitive miRNA Imaging in Living Cells

Analytical Chemistry
2025-04-08 | Journal article
DOI: 10.1021/acs.analchem.5c01163
Contributors: Ting Huang; Naihan Huang; Qianying Zhou; Baoping Xie; Wenjun Duan; Bin Sun; Zong Dai; Jun Chen; Jin-Xiang Chen
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Gold-nanoparticles aggregation based colorimetric strategy to accurately quantify genome-wide global 5-hydroxymethylcytosine in mammalian tissues

Microchemical Journal
2025-02 | Journal article
DOI: 10.1016/j.microc.2025.112686
Contributors: Zhenning Yu; Jiaying Xiong; Yakun Shi; Chunrong Li; Yanfei Zhang; Zong Dai
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A novel aptasensor based endogenous enzyme-powered DNA walker for ATP imaging in specific living cells

Chemical Communications
2024 | Journal article
DOI: 10.1039/D4CC04681A
Contributors: Chunrong Li; Tong Li; Mingqi Guo; Tiehong Meng; Jing Peng; Simin Liu; Qianyu Wang; Baoping Xie; Zong Dai; Jun Chen
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Aptasensor based on gold nanostructure-decorated 2D Cu metal–organic framework nanosheets for highly sensitive and specific electrochemical lipopolysaccharide detection

Microchimica Acta
2024-08 | Journal article
DOI: 10.1007/s00604-024-06587-8
Contributors: Yanli Tong; Meng Chen; Xing Huang; Yuzhi Xu; Lang Zhang; Zhenning Yu; Si-Yang Liu; Zong Dai
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CRISPR/Pepper‐tDeg: A Live Imaging System Enables Non‐Repetitive Genomic Locus Analysis with One Single‐Guide RNA

Advanced Science
2024-08 | Journal article
DOI: 10.1002/advs.202402534
Contributors: Meng Chen; Xing Huang; Yakun Shi; Wen Wang; Zhan Huang; Yanli Tong; Xiaoyong Zou; Yuzhi Xu; Zong Dai
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Toehold Strand Displacement-Mediated Exponential HCR for Highly Sensitive and Specific Analysis of miRNA in Living Cells

Analytical Chemistry
2024-06-04 | Journal article
DOI: 10.1021/acs.analchem.4c00594
Contributors: Mengxu Sun; Qianying Zhou; Jing Peng; Simin Liu; Jiaxin Luo; Lingling Bai; Wen-Jun Duan; Jin-Xiang Chen; Zong Dai; Jun Chen
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MiRNA and mRNA-Controlled Double-Cascaded Amplifying Circuit Nanosensor for Accurate Discrimination of Breast Cancers in Living Cells, Animals, and Organoids

Analytical Chemistry
2024-03-12 | Journal article
DOI: 10.1021/acs.analchem.3c05085
Contributors: Huihui Yang; Dong Chen; Yanfei Zhang; Peixiu Yuan; Ni Xie; Zong Dai
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A Simple and Robust Exponential Amplification Reaction (EXPAR)-Based Hairpin Template (exp-Hairpin) for Highly Specific, Sensitive, and Universal MicroRNA Detection

Analytical Chemistry
2024-02-13 | Journal article
DOI: 10.1021/acs.analchem.3c05323
Contributors: Haijing Guo; Jun Chen; Yaqiang Feng; Zong Dai
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Bioorthogonal Activation of RCA-Based Amplifiable DNAzymes in Bimetallic NMOF for Precise Gene/Chemo-Dynamic Combination Therapy

ACS Materials Letters
2024-02-05 | Journal article
DOI: 10.1021/acsmaterialslett.3c01338
Contributors: Ting Huang; Wei-Lun Pan; Ming-Shun Li; Yi-Ming Zou; Wei Meng; Min-Min Li; Wen-Hua Zhang; Zong Dai; Jin-Xiang Chen; Jun Chen
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Dephosphorylation Switch DNAzyme-RCA Circuit: A Robust Strategy for the Homogeneous and Reliable Detection of FTO Demethylase

Analytical Chemistry
2024-01-30 | Journal article
DOI: 10.1021/acs.analchem.3c04762
Contributors: Taorong Shen; Xing Huang; Yanfei Zhang; Yanli Tong; Yakun Shi; Jianhe Guo; Xiaoyong Zou; Yuzhi Xu; Zong Dai
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Dual-Signal Amplification Strategy Based on Catalytic Hairpin Assembly and APE1-Assisted Amplification for High-Contrast miRNA Imaging in Living Cells

Analytical Chemistry
2024-01-16 | Journal article
DOI: 10.1021/acs.analchem.3c05013
Contributors: Ya Zhang; Mengxu Sun; Juan Xie; Jing Chen; Ting Huang; Wen-Jun Duan; Jin-Xiang Chen; Jun Chen; Zong Dai; Minmin Li
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Design of portable electrochemiluminescence sensing systems for point-of-care-testing applications

Chinese Chemical Letters
2023-05 | Journal article
DOI: 10.1016/j.cclet.2022.107799
Contributors: Shuqi Xia; Jiangfei Pan; Deshen Dai; Zong Dai; Mengsu Yang; Changqing Yi
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Isolation of Structurally Heterogeneous TCR‐CD3 Extracellular Vesicle Subpopulations Using Caliper Strategy

Angewandte Chemie International Edition
2023-04-24 | Journal article
DOI: 10.1002/anie.202300954
Contributors: Wen Yin; Haitian Chen; Jianye Cai; Xing Huang; Lang Zhang; Yuzhi Xu; Jun Zheng; Si‐Yang Liu; Xiaoyong Zou; Zong Dai et al.
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Isolation of Structurally Heterogeneous TCR‐CD3 Extracellular Vesicle Subpopulations Using Caliper Strategy

Angewandte Chemie
2023-04-24 | Journal article
DOI: 10.1002/ange.202300954
Contributors: Wen Yin; Haitian Chen; Jianye Cai; Xing Huang; Lang Zhang; Yuzhi Xu; Jun Zheng; Si‐Yang Liu; Xiaoyong Zou; Zong Dai et al.
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A photo-elutable and template-free isothermal amplification strategy for sensitive fluorescence detection of 5-formylcytosine in genomic DNA

Chinese Chemical Letters
2023-03 | Journal article
DOI: 10.1016/j.cclet.2022.05.050
Contributors: Hongling Yang; Yanfei Zhang; Zhenning Yu; Si-Yang Liu; Yuzhi Xu; Zong Dai; Xiaoyong Zou
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A domino-like localized cascade toehold assembly amplification-based DNA nanowire for microRNA imaging in living cells

Chemical Science
2022 | Journal article
DOI: 10.1039/D2SC05890A
Contributors: Zizhong Yang; Birong Liu; Ting Huang; Mengxu Sun; Tong li; Wen-Jun Duan; Min-Min Li; Jin-Xiang Chen; Zong Dai; Jun Chen
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A universal rolling circle amplification for label-free and highly specific nucleic acid sensing

Chemical Communications
2022 | Journal article
DOI: 10.1039/D2CC04058A
Contributors: Mengxu Sun; Birong Liu; Tong Li; Chunrong Li; Wen-Jun Duan; Baoping Xie; Min-Min Li; Jin-Xiang Chen; Zong Dai; Jun Chen
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Dual-Locked DNAzyme Platform for In Vitro and In Vivo Discrimination of Cancer Cells

Analytical Chemistry
2022-09-06 | Journal article
DOI: 10.1021/acs.analchem.2c02788
Contributors: Xing Huang; Yanfei Zhang; Jun Chen; Lang Zhang; Yuzhi Xu; Wen Yin; Yakun Shi; Si-Yang Liu; Xiaoyong Zou; Zong Dai
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Highly Efficient Isolation and Sensitive Detection of Small Extracellular Vesicles Using a Paper-Based Device

Analytical Chemistry
2022-08-09 | Journal article
DOI: 10.1021/acs.analchem.2c01378
Contributors: Lang Zhang; Wen Yin; Yanli Tong; Yanfei Zhang; Yuzhi Xu; Si-Yang Liu; Zong Dai; Xiaoyong Zou
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Label-free and highly sensitive APE1 detection based on rolling circle amplification combined with G-quadruplex

Talanta
2022-07 | Journal article
DOI: 10.1016/j.talanta.2022.123404
Contributors: Birong Liu; Zizhong Yang; Ting Huang; Min-Min Li; Wenjun Duan; Baoping Xie; Jin-Xiang Chen; Zong Dai; Jun Chen
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NanoSuit-Assisted Liquid-Cell Scanning Electron Microscopy Enables Dynamic Gold Nanoparticle Monitoring for the Aggregation and Transmembrane Processes in Living Cells

Nano Letters
2022-07-27 | Journal article
DOI: 10.1021/acs.nanolett.2c01251
Contributors: Wen Yin; Yanfei Zhang; Yuling Liang; Hui-Hui Yang; Yuzhi Xu; Si-Yang Liu; Jianhua Zhou; Zong Dai; Xiaoyong Zou
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Light-Controlled Recruitable Hybridization Chain Reaction on Exosome Vehicles for Highly Sensitive MicroRNA Imaging in Living Cells

Analytical Chemistry
2022-07-12 | Journal article
DOI: 10.1021/acs.analchem.2c00974
Contributors: Yanfei Zhang; Jun Chen; Huihui Yang; Wen Yin; Chunrong Li; Yuzhi Xu; Si-Yang Liu; Zong Dai; Xiaoyong Zou
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Smart Hairpins@MnO2 Nanosystem Enables Target-Triggered Enzyme-Free Exponential Amplification for Ultrasensitive Imaging of Intracellular MicroRNAs in Living Cells

Analytical Chemistry
2022-06-07 | Journal article
DOI: 10.1021/acs.analchem.2c01211
Contributors: Zizhong Yang; Birong Liu; Ting Huang; Bao-Ping Xie; Wen-Jun Duan; Min-Min Li; Jin-Xiang Chen; Jun Chen; Zong Dai
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Cancer cell identification by facile imaging of intracellular reductive substances with fluorescent nanosensor

Talanta
2021-11 | Journal article
DOI: 10.1016/j.talanta.2021.122650
Contributors: Chunrong Li; Yuzhi Xu; Si-Yang Liu; Yanfei Zhang; Wen Yin; Zong Dai; Xiaoyong Zou
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Highly Sensitive Fluorescence Detection of Global 5-Hydroxymethylcytosine from Nanogram Input with Strongly Emitting Copper Nanotags

Analytical Chemistry
2021-10-26 | Journal article
DOI: 10.1021/acs.analchem.1c03266
Contributors: Zhenning Yu; Yanli Tong; Yuling Liang; Yunda Li; Hongling Yang; Si-Yang Liu; Yuzhi Xu; Zong Dai; Xiaoyong Zou
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A MOF-Shell-Confined I-Motif-Based pH Probe (MOFC-i) Strategy for Sensitive and Dynamic Imaging of Cell Surface pH

ACS Applied Materials & Interfaces
2021-09-29 | Journal article
DOI: 10.1021/acsami.1c13720
Contributors: Huihui Yang; Jun Chen; Yuling Liang; Yanfei Zhang; Wen Yin; Yuzhi Xu; Si-Yang Liu; Zong Dai; Xiaoyong Zou
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Isothermal Self-Primer EXPonential Amplification Reaction (SPEXPAR) for Highly Sensitive Detection of Single-Stranded Nucleic Acids and Proteins

Analytical Chemistry
2021-09-21 | Journal article
DOI: 10.1021/acs.analchem.1c02588
Contributors: Jun Chen; Daozhong Zhu; Ting Huang; Zizhong Yang; Birong Liu; Mengxu Sun; Jin-Xiang Chen; Zong Dai; Xiaoyong Zou
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Pearl Necklacelike Strategy Enables Quantification of Global 5-Hydroxymethylcytosine and 5-Formylcytosine by Inductively Coupled Plasma-Atomic Emission Spectrometry

Analytical Chemistry
2021-06-08 | Journal article
DOI: 10.1021/acs.analchem.1c01548
Contributors: Zhenning Yu; Si-Yang Liu; Yanfei Zhang; Yunda Li; Yuzhi Xu; Danping Chen; Zong Dai; Xiaoyong Zou
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Fluorescence on-off-on with small and charge-tunable nanoparticles enables highly sensitive intracellular microRNA imaging in living cells

Talanta
2021-05 | Journal article
DOI: 10.1016/j.talanta.2021.122114
Contributors: Chunrong Li; Yanfei Zhang; Jun Chen; Liping Liu; Huihui Yang; Si-Yang Liu; Yuzhi Xu; Zong Dai; Xiaoyong Zou
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Ultrathin 2D Copper(I) 1,2,4‐Triazolate Coordination Polymer Nanosheets for Efficient and Selective Gene Silencing and Photodynamic Therapy

Advanced Materials
2021-05 | Journal article
DOI: 10.1002/adma.202100849
Contributors: Si‐Yang Liu; Yuzhi Xu; Huihui Yang; Liping Liu; Meiting Zhao; Wen Yin; Yan‐Tong Xu; Ying Huang; Chaoliang Tan; Zong Dai et al.
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Novel Potential Small Molecule–MiRNA–Cancer Associations Prediction Model Based on Fingerprint, Sequence, and Clinical Symptoms

Journal of Chemical Information and Modeling
2021-05-24 | Journal article
DOI: 10.1021/acs.jcim.0c01458
Contributors: Jinlong Li; Dongdong Peng; Yun Xie; Zong Dai; Xiaoyong Zou; Zhanchao Li
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A protein triggering exponential amplification reaction enables label- and wash-free one-pot protein assay with high sensitivity

Talanta
2021-04 | Journal article
DOI: 10.1016/j.talanta.2020.121980
Contributors: Jun Chen; Yanfei Zhang; Bao-Ping Xie; Bin Sun; Wen-Jun Duan; Min-Min Li; Jin-Xiang Chen; Zong Dai; Xiaoyong Zou
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A deep learning approach to identify association of disease–gene using information of disease symptoms and protein sequences

Analytical Methods
2020 | Journal article
DOI: 10.1039/C9AY02333J
Contributors: Xingyu Chen; Qixing Huang; Yang Wang; Jinlong Li; Haiyan Liu; Yun Xie; Zong Dai; Xiaoyong Zou; Zhanchao Li
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A new amplification strategy for a quartz crystal microbalance miRNA sensor based on selective interactions between a metal–organic framework and miRNA

New Journal of Chemistry
2020 | Journal article
DOI: 10.1039/C9NJ04600C
Contributors: Ding Ma; Sheng-Run Zheng; Jun Fan; Song-Liang Cai; Zong Dai; Xiao-Yong Zou; Shao-Hua Teng; Wei-Guang Zhang
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Polymerization retardation isothermal amplification strategy enables the sensitive and facile investigation of the flanking sequence preference of ten-eleven translocation 2 protein

Analytica Chimica Acta
2020-05 | Journal article
DOI: 10.1016/j.aca.2020.02.038
Contributors: Danping Chen; Yang Wang; Jun Chen; Yanfei Zhang; Zong Dai; Xiaoyong Zou
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A new QCM signal enhancement strategy based on streptavidin@metal-organic framework complex for miRNA detection

Analytica Chimica Acta
2020-01 | Journal article
DOI: 10.1016/j.aca.2019.10.034
Contributors: Ding Ma; Sheng-Run Zheng; Jun Fan; Song-Liang Cai; Zong Dai; Xiao-Yong Zou; Shao-Hua Teng; Wei-Guang Zhang
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Selective and rapid detection of mercury ion based on DNA assembly and nicking endonuclease-assisted signal amplification

Analytical Methods
2019 | Journal article
DOI: 10.1039/C9AY00656G
Contributors: Junling Liu; Liping Liu; Jun Chen; Tianchen Wang; Yuzhi Xu; Zong Dai; Xiaoyong Zou
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Sensitive and sustained imaging of intracellular microRNA in living cells by a high biocompatible liposomal vehicle introduced isothermal symmetric exponential amplification reaction

Chemical Communications
2019 | Journal article
DOI: 10.1039/C9CC05583E
Contributors: Wen Yin; Jun Chen; Huihui Yang; Yanfei Zhang; Zong Dai; Xiaoyong Zou
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Front Cover: In Situ Enzyme Immobilization with Oxygen‐Sensitive Luminescent Metal–Organic Frameworks to Realize “All‐in‐One” Multifunctions (Chem. Eur. J. 21/2019)

Chemistry – A European Journal
2019-04-11 | Journal article
DOI: 10.1002/chem.201901048
Contributors: Yuzhi Xu; Si‐Yang Liu; Junling Liu; Li Zhang; Danping Chen; Jun Chen; Yingjun Ma; Jie‐Peng Zhang; Zong Dai; Xiaoyong Zou
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In Situ Enzyme Immobilization with Oxygen‐Sensitive Luminescent Metal–Organic Frameworks to Realize “All‐in‐One” Multifunctions

Chemistry – A European Journal
2019-04-11 | Journal article
DOI: 10.1002/chem.201806146
Contributors: Yuzhi Xu; Si‐Yang Liu; Junling Liu; Li Zhang; Danping Chen; Jun Chen; Yingjun Ma; Jie‐Peng Zhang; Zong Dai; Xiaoyong Zou
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Crossref

In Situ Enzyme Immobilization with Oxygen‐Sensitive Luminescent Metal–Organic Frameworks to Realize “All‐in‐One” Multifunctions

Chemistry – A European Journal
2019-04-11 | Journal article
DOI: 10.1002/chem.201901049
Contributors: Yuzhi Xu; Si‐Yang Liu; Junling Liu; Li Zhang; Danping Chen; Jun Chen; Yingjun Ma; Jie‐Peng Zhang; Zong Dai; Xiaoyong Zou
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Metastable Dumbbell Probe-Based Hybridization Chain Reaction for Sensitive and Accurate Imaging of Intracellular-Specific MicroRNAs In Situ in Living Cells

Analytical Chemistry
2019-04-02 | Journal article
DOI: 10.1021/acs.analchem.8b05920
Contributors: Jun Chen; Hui-Hui Yang; Wen Yin; Yanfei Zhang; Yingjun Ma; Danping Chen; Yuzhi Xu; Si-Yang Liu; Li Zhang; Zong Dai et al.
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Imaging of intracellular-specific microRNA in tumor cells by symmetric exponential amplification-assisted fluorescence in situ hybridization

Chemical Communications
2018 | Journal article
DOI: 10.1039/C8CC08849G
Contributors: Jun Chen; Wen Yin; Yingjun Ma; Huihui Yang; Yanfei Zhang; Mengfei Xu; Xuling Zheng; Zong Dai; Xiaoyong Zou
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Real-Time Sensing of TET2-Mediated DNA Demethylation In Vitro by Metal–Organic Framework-Based Oxygen Sensor for Mechanism Analysis and Stem-Cell Behavior Prediction

Analytical Chemistry
2018-08-07 | Journal article
DOI: 10.1021/acs.analchem.8b01941
Contributors: Yuzhi Xu; Si-Yang Liu; Jie Li; Li Zhang; Danping Chen; Jie-Peng Zhang; Yanhui Xu; Zong Dai; Xiaoyong Zou
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Isothermal Amplification on a Structure-Switchable Symmetric Toehold Dumbbell-Template: A Strategy Enabling MicroRNA Analysis at the Single-Cell Level with Ultrahigh Specificity and Accuracy

Analytical Chemistry
2018-01-02 | Journal article
DOI: 10.1021/acs.analchem.7b03713
Contributors: Jun Chen; Taixue An; Yingjun Ma; Bo Situ; Danping Chen; Yuzhi Xu; Li Zhang; Zong Dai; Xiaoyong Zou
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