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Biography

My lab has multiple research avenues that each leverage a culture technique called the air-liquid interface. Using the air-liquid interface culture method, we generate functioning human airway mucociliary tissue cultures in-vitro that are derived from primary stem cells isolated by simple nasal brushing of donors’ nasal passages. We use these human in-vitro respiratory tissue cultures for a variety of research projects aimed at generating translational data on the pathogenesis and treatment of current human respiratory conditions, including e-cigarette toxicity, personalized asthma medicine, and lung cancer modeling.

Activities

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Employment (2)

Rowan-Virtua School of Osteopathic Medicine: Stratford, New Jersey, US

2024-04-21 to present | Assistant Professor (Molecular Biology)
Employment
Source: Self-asserted source
Vincent Manna

Rowan University School of Osteopathic Medicine: Stratford, NJ, US

2021-08-31 to 2024-04-21 | Research Teaching Specialist (Molecular Biology)
Employment
Source: Self-asserted source
Vincent Manna

Education and qualifications (2)

Rowan University Department of Molecular Biology: Stratford, NJ, US

2021-08-30 | Ph.D. Cell and Molecular Biology (Molecular Biology)
Education
Source: Self-asserted source
Vincent Manna

Richard Stockton College of New Jersey: Galloway, NJ, US

2013-06-30 | B.S. Biology (Biology)
Education
Source: Self-asserted source
Vincent Manna

Funding (1)

Exploring how commercially available tobacco flavored E-cigarette aerosols impact human airway mucociliary tissue homeostasis and regeneration

2023 to present | Grant
New Jersey Health Foundation (New Brunswick, US)
Source: Self-asserted source
Vincent Manna

Works (6)

Inhibition of lysine deacetylase activity impacts formation of the vitamin D receptor activation complex

2025-02-03 | Preprint
DOI: 10.1101/2025.02.03.636272
Contributors: Shannon Dwyer; Kevin Kemper; Vincent J. Manna
Source: check_circle
Crossref

The dynamic nature of the coronavirus receptor, angiotensin-converting enzyme 2 (ACE2) in differentiating airway epithelia

BBA Advances
2022 | Journal article
DOI: 10.1016/j.bbadva.2022.100044
Part of ISSN: 2667-1603
Contributors: Vincent Manna; Vincent J. Manna; Hana Choi; Shawna M. Rotoli; Salvatore Caradonna
Source: Self-asserted source
Vincent Manna

Human Airway Mucociliary Tissue Cultures Chronically Exposed to E-Cigarette Vapors Exhibit Altered Cell Populations and Increased Secretion of Immunomodulatory Cytokines

2022-12-14 | Preprint
DOI: 10.1101/2022.12.12.520128
Contributors: Vincent J. Manna; Shannon Dwyer; Vanessa Pizutelli; Salvatore J. Caradonna
Source: check_circle
Crossref

Isolation, expansion, differentiation, and histological processing of human nasal epithelial cells

STAR Protocols
2021-12 | Journal article
DOI: 10.1016/j.xpro.2021.100782
Contributors: Vincent Manna; Salvatore Caradonna
Source: check_circle
Crossref

The heterogeneous nature of the Coronavirus receptor, angiotensin-converting enzyme 2 (ACE2) in differentiating airway epithelia

[]
2020-07-09 | Preprint
DOI: 10.1101/2020.07.09.190074
Source: Self-asserted source
Vincent Manna

Inhibition of post-transcriptional steps in ribosome biogenesis confers cytoprotection against chemotherapeutic agents in a p53-dependent manner.

Scientific reports
2017-08-22 | Journal article
DOI: 10.1038/s41598-017-09002-w
PMID: 28831158
PMC: PMC5567254
Source: Self-asserted source
Vincent Manna

Peer review (9 reviews for 1 publication/grant)

Review activity for STAR protocols. (9)
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