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Cobb Group Homepage

Other IDs

ResearcherID: F-3926-2012

Keywords

Peptides, Peptoids, Chemical-Biology, Fluorine, Organic Chemistry

Countries

United Kingdom

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Employment (1)

Durham University: Durham, Durham, GB

2020-10-01 to present | Professor (Chemistry )
Employment
Source: Self-asserted source
Steven Cobb

Works (50 of 61)

Items per page:
Page 1 of 2

Salivary Antimicrobial Peptide Histatin-5 Does Not Display Zn(II)-Dependent or -Independent Activity against Streptococci

ACS Infectious Diseases
2023-03-10 | Journal article
DOI: 10.1021/acsinfecdis.2c00578
Contributors: Louisa J. Stewart; YoungJin Hong; Isabel R. Holmes; Samantha J. Firth; Yasmin Ahmed; Janet Quinn; Yazmin Santos; Steven L. Cobb; Nicholas S. Jakubovics; Karrera Y. Djoko
Source: check_circle
Crossref

One-pot ester and thioester formation mediated by pentafluoropyridine (PFP)

Organic & Biomolecular Chemistry
2022 | Journal article
DOI: 10.1039/D2OB01268E
Contributors: Liam N. D. Beardmore; Steven L. Cobb; William D. G. Brittain
Source: check_circle
Crossref

Aminoacyl chain translocation catalysed by a type II thioesterase domain in an unusual non-ribosomal peptide synthetase

Nature Communications
2022-01-10 | Journal article
DOI: 10.1038/s41467-021-27512-0
Contributors: Shan Wang; William D. G. Brittain; Qian Zhang; Zhou Lu; Ming Him Tong; Kewen Wu; Kwaku Kyeremeh; Matthew Jenner; Yi Yu; Steven L. Cobb et al.
Source: check_circle
Crossref

Carboxylic Acid Deoxyfluorination and One-Pot Amide Bond Formation Using Pentafluoropyridine (PFP)

Organic Letters
2021-08-06 | Journal article
DOI: 10.1021/acs.orglett.1c01953
Contributors: William D. G. Brittain; Steven L. Cobb
Source: check_circle
Crossref

Peptoids with Antibiofilm Activity against the Gram Negative Obligate Anaerobe, Fusobacterium nucleatum

Molecules
2021-08-05 | Journal article
DOI: 10.3390/molecules26164741
Contributors: Jamie Toole; Hannah L. Bolt; John J. Marley; Sheila Patrick; Steven L. Cobb; Fionnuala T. Lundy
Source: check_circle
Crossref
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Preferred source (of 2)‎

Fengycin A Analogues with Enhanced Chemical Stability and Antifungal Properties

Organic Letters
2021-06-18 | Journal article
DOI: 10.1021/acs.orglett.1c01387
Contributors: Diana Gimenez; Aoife Phelan; Cormac D. Murphy; Steven L. Cobb
Source: check_circle
Crossref

19F NMR as a tool in chemical biology

Beilstein Journal of Organic Chemistry
2021-01-28 | Journal article
DOI: 10.3762/bjoc.17.28
Contributors: Diana Gimenez; Aoife Phelan; Cormac D Murphy; Steven L Cobb
Source: check_circle
Crossref

Introduction to the themed collection on ‘Neglected tropical diseases’

RSC Medicinal Chemistry
2020 | Journal article
DOI: 10.1039/D0MD90030C
Contributors: Nahid Ali; Steven L. Cobb; Charles Mowbray
Source: check_circle
Crossref

N-Terminal speciation for native chemical ligation

Chemical Communications
2020 | Journal article
DOI: 10.1039/D0CC01604G
Contributors: Oliver R. Maguire; Jiayun Zhu; William D. G. Brittain; Alexander S. Hudson; Steven L. Cobb; AnnMarie C. O’Donoghue
Source: check_circle
Crossref

Recent advances in the development of anti-infective peptoids

Chemical Communications
2020 | Journal article
DOI: 10.1039/D0CC04704J
Contributors: Kevin L. Bicker; Steven L Cobb
Source: check_circle
Crossref

Unusually high α-proton acidity of prolyl residues in cyclic peptides

Chemical Science
2020 | Journal article
DOI: 10.1039/D0SC02508A
Contributors: Oliver R. Maguire; Bethany Taylor; Eleanor M. Higgins; Matthew Rees; Steven L. Cobb; Nigel S. Simpkins; Christopher J. Hayes; AnnMarie C. O'Donoghue
Source: check_circle
Crossref

Protecting Group-Controlled Remote Regioselective Electrophilic Aromatic Halogenation Reactions

The Journal of Organic Chemistry
2020-06-05 | Journal article
DOI: 10.1021/acs.joc.9b03322
Contributors: William D. G. Brittain; Steven L. Cobb
Source: check_circle
Crossref

An enzymatic Finkelstein reaction: fluorinase catalyses direct halogen exchange

Organic & Biomolecular Chemistry
2019 | Journal article
DOI: 10.1039/C9OB01625B
Contributors: Phillip T. Lowe; Steven L. Cobb; David O'Hagan
Source: check_circle
Crossref

Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditions

Organic & Biomolecular Chemistry
2019 | Journal article
DOI: 10.1039/C8OB02899K
Contributors: William D. G. Brittain; Steven L. Cobb
Source: check_circle
Crossref

Remote Regioselective Electrophilic Aromatic Substitutions Using a Tetrafluoropyridyl (TFP) Phenol Protecting Group

2019-10-16 | Other
DOI: 10.26434/chemrxiv.9963293.v1
Contributors: William Brittain; Steven Cobb
Source: check_circle
Crossref

Fluorinated Aromatic Monomers as Building Blocks To Control α-Peptoid Conformation and Structure

Journal of the American Chemical Society
2019-02-27 | Journal article
DOI: 10.1021/jacs.8b13498
Contributors: Diana Gimenez; Guangfeng Zhou; Matthew F. D. Hurley; Juan A. Aguilar; Vincent A. Voelz; Steven L. Cobb
Source: check_circle
Crossref

Negishi cross-couplings in the synthesis of amino acids

Organic & Biomolecular Chemistry
2018 | Journal article
DOI: 10.1039/C7OB02682J
Contributors: William D. G. Brittain; Steven L. Cobb
Source: check_circle
Crossref

Short elastin-like peptide-functionalized gold nanoparticles that are temperature responsive under near-physiological conditions

Journal of Materials Chemistry B
2018 | Journal article
DOI: 10.1039/C8TB01827H
Contributors: Jingyi Zong; Steven L. Cobb; Neil R. Cameron
Source: check_circle
Crossref

Stabilising Peptoid Helices Using Non‐Chiral Fluoroalkyl Monomers

Angewandte Chemie
2018-08-13 | Journal article
DOI: 10.1002/ange.201804488
Contributors: Diana Gimenez; Juan A. Aguilar; Elizabeth H. C. Bromley; Steven L. Cobb
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Crossref

Stabilising Peptoid Helices Using Non‐Chiral Fluoroalkyl Monomers

Angewandte Chemie International Edition
2018-08-13 | Journal article
DOI: 10.1002/anie.201804488
Contributors: Diana Gimenez; Juan A. Aguilar; Elizabeth H. C. Bromley; Steven L. Cobb
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Crossref

Frontispiece: Recent Advances in the Synthesis of Peptoid Macrocycles

Chemistry – A European Journal
2018-05-28 | Journal article
DOI: 10.1002/chem.201883062
Contributors: Alexandra M. Webster; Steven L. Cobb
Source: check_circle
Crossref

Recent Advances in the Synthesis of Peptoid Macrocycles

Chemistry – A European Journal
2018-05-28 | Journal article
DOI: 10.1002/chem.201705340
Contributors: Alexandra M. Webster; Steven L. Cobb
Source: check_circle
Crossref

2,2,2-Trifluoroethanol as a solvent to control nucleophilic peptide arylation

Organic & Biomolecular Chemistry
2017 | Journal article
DOI: 10.1039/C7OB00295E
Contributors: Diana Gimenez; Anica Dose; Nicholas L. Robson; Graham Sandford; Steven L. Cobb; Christopher R. Coxon
Source: check_circle
Crossref

Exploring the links between peptoid antibacterial activity and toxicity

MedChemComm
2017 | Journal article
DOI: 10.1039/C6MD00648E
Contributors: H. L. Bolt; G. A. Eggimann; C. A. B. Jahoda; R. N. Zuckermann; G. J. Sharples; S. L. Cobb
Source: check_circle
Crossref

Peptide-functionalized gold nanoparticles: versatile biomaterials for diagnostic and therapeutic applications

Biomaterials Science
2017 | Journal article
DOI: 10.1039/C7BM00006E
Contributors: Jingyi Zong; Steven L. Cobb; Neil R. Cameron
Source: check_circle
Crossref

The application of perfluoroheteroaromatic reagents in the preparation of modified peptide systems

Organic & Biomolecular Chemistry
2017 | Journal article
DOI: 10.1039/C7OB00283A
Contributors: Diana Gimenez; Caitlin A. Mooney; Anica Dose; Graham Sandford; Christopher R. Coxon; Steven L. Cobb
Source: check_circle
Crossref

A direct method for the synthesis of orthogonally protected furyl- and thienyl- amino acids

Amino Acids
2015 | Journal article
WOSUID:

CCC:000351383900011
Contributors: Hudson, Alex S.; Caron, Laurent; Colgin, Neil; Cobb, Steven L.
Source: Self-asserted source
Steven Cobb via ResearcherID

Directional Plk1 inhibition-driven cell cycle interruption using amphiphilic thin-coated peptide-lanthanide upconversion nanomaterials as in vivo tumor suppressors

Journal of Materials Chemistry B
2015 | Journal article
DOI: 10.1039/c4tb02104e
WOSUID:

WOS:000351599400006
Contributors: Chan, Chi-Fai; Lan, Rongfeng; Tsang, Ming-Kiu; Zhou, Di; Lear, Sam; Chan, Wai-Lun; Cobb, Steven L.; Wong, Wai-Kwok; Hao, Jianhua; Wong, Wing-Tak et al.
Source: Self-asserted source
Steven Cobb via ResearcherID

Excited State Dynamics of the Isolated Green Fluorescent Protein Chromophore Anion Following UV Excitation

Journal of Physical Chemistry B
2015 | Journal article
WOSUID:

CCC:000351188300011
Contributors: West, Christopher W.; Bull, James N.; Hudson, Alex S.; Cobb, Steven L.; Verlet, Jan R. R.
Source: Self-asserted source
Steven Cobb via ResearcherID

Investigating the Anti-leishmanial Effects of Linear Peptoids

Chemmedchem
2015 | Journal article
DOI: 10.1002/cmdc.201402416
WOSUID:

WOS:000348710100002
Contributors: Eggimann, Gabriela A.; Bolt, Hannah L.; Denny, Paul W.; Cobb, Steven L.
Source: Self-asserted source
Steven Cobb via ResearcherID

Synthesis, Ni(II) Schiff base complexation and structural analysis of fluorinated analogs of the ligand (S)-2-[N-(N '-benzylprolyl)amino]benzophenone (BPB)

Journal of Fluorine Chemistry
2015 | Journal article
DOI: 10.1016/j.jfluchem.2015.02.007
WOSUID:

WOS:000353087000012
Contributors: Tatum, Natalie J.; Yufit, Dmitry S.; Cobb, Steven L.; Coxon, Christopher R.
Source: Self-asserted source
Steven Cobb via ResearcherID

The Role of Phosphoglycans in the Susceptibility of Leishmania mexicana to the Temporin Family of Anti-Microbial Peptides

Molecules
2015 | Journal article
DOI: 10.3390/molecules20022775
WOSUID:

WOS:000350748200055
Contributors: Eggimann, Gabriela A.; Sweeney, Kathryn; Bolt, Hannah L.; Rozatian, Neshat; Cobb, Steven L.; Denny, Paul W.
Source: Self-asserted source
Steven Cobb via ResearcherID

A mild method for the synthesis of a novel dehydrobutyrine-containing amino acid

Tetrahedron
2014 | Journal article
DOI: 10.1016/j.tet.2014.05.031
WOSUID:

WOS:000337868600012
Contributors: Webster, Alexandra M.; Coxon, Christopher R.; Kenwright, Alan M.; Sandford, Graham; Cobb, Steven L.
Source: Self-asserted source
Steven Cobb via ResearcherID

Bifunctional up-converting lanthanide nanoparticles for selective in vitro imaging and inhibition of cyclin D as anti-cancer agents

Journal of Materials Chemistry B
2014 | Journal article
DOI: 10.1039/c3tb21034k
WOSUID:

WOS:000327607100010
Contributors: Chan, Chi-Fai; Tsang, Ming-Kiu; Li, Hongguang; Lan, Rongfeng; Chadbourne, Frances L.; Chan, Wai-Lun; Law, Ga-Lai; Cobb, Steven L.; Hao, Jianhua; Wong, Wing-Tak et al.
Source: Self-asserted source
Steven Cobb via ResearcherID

Blending Gelators to Tune Gel Structure and Probe Anion-Induced Disassembly

Chemistry-a European Journal
2014 | Journal article
DOI: 10.1002/chem.201303153
WOSUID:

WOS:000328714700033
Contributors: Foster, Jonathan A.; Edkins, Robert M.; Cameron, Gary J.; Colgin, Neil; Fucke, Katharina; Ridgeway, Sam; Crawford, Andrew G.; Marder, Todd B.; Beeby, Andrew; Cobb, Steven L. et al.
Source: Self-asserted source
Steven Cobb via ResearcherID

FROM DI-PEPTIDES TO WHOLE PROTEINS: EXPLOITING PEPTIDE CHEMISTRY IN THE TOTAL SYNTHESIS OF CCL2 AND THE RATIONAL DESIGN OF NEW CHEMOKINE INHIBITORS

Journal of Peptide Science
2014 | Journal article
WOSUID:

WOS:000340876400094
Contributors: Hudson, A. S.; Kirby, J. A.; Ali, S.; Colgin, N.; Caron, Cl.; Cobb, S. L.
Source: Self-asserted source
Steven Cobb via ResearcherID

Monitoring and inhibition of Plk1: amphiphilic porphyrin conjugated Plk1 specific peptides for its imaging and anti-tumor function.

Organic & biomolecular chemistry
2014 | Journal article
DOI: 10.1039/c4ob00853g
WOSUID:

MEDLINE:24977405
Contributors: Li, Hongguang; Chan, Chi-Fai; Chan, Wai-Lun; Lear, Sam; Cobb, Steven L; Mak, Nai-Ki; Lau, Terrence Chi-Kong; Lan, Rongfeng; Wong, Wai-Kwok; Wong, Ka-Leung
Source: Self-asserted source
Steven Cobb via ResearcherID

Novel fluorinated lipopeptides from Bacillus sp. CS93 via precursor-directed biosynthesis

Amino Acids
2014 | Journal article
WOSUID:

CCC:000345073100011
Contributors: O'Connor, Neil K.; Hudson, Alex S.; Cobb, Steven L.; O'Neil, Deborah; Robertson, Jennifer; Duncan, Vanessa; Murphy, Cormac D.
Source: Self-asserted source
Steven Cobb via ResearcherID

Aqueous synthesis of N,S-dialkylthiophosphoramidates: design, optimisation and application to library construction and antileishmanial testing

Organic & Biomolecular Chemistry
2013 | Journal article
DOI: 10.1039/c3ob27448a
WOSUID:

WOS:000316803900016
Contributors: Trmcic, Milena; Chadbourne, Frances L.; Brear, Paul M.; Denny, Paul W.; Cobb, Steven L.; Hodgson, David R. W.
Source: Self-asserted source
Steven Cobb via ResearcherID

Communication: Autodetachment versus internal conversion from the S-1 state of the isolated GFP chromophore anion

Journal of Chemical Physics
2013 | Journal article
DOI: 10.1063/1.4819078
WOSUID:

WOS:000323509900004
Contributors: West, Christopher W.; Hudson, Alex S.; Cobb, Steven L.; Verlet, Jan R. R.
Source: Self-asserted source
Steven Cobb via ResearcherID

Contribution of heparan sulphate binding domain of chemokine CCL21 to trans-endothelial migration of breast cancer cells

Immunology
2013 | Journal article
WOSUID:

WOS:000327487700159
Contributors: Malki, M. I.; Cobb, S.; Pohl, E.; Kirby, J.; Ali, S.
Source: Self-asserted source
Steven Cobb via ResearcherID

Evaluation of two cyclic di-peptides as inhibitors of CCL2 induced chemotaxis

Medchemcomm
2013 | Journal article
DOI: 10.1039/c3md00043e
WOSUID:

WOS:000318302500025
Contributors: Saleki, Mahsa; Colgin, Neil; Kirby, John A.; Cobb, Steven L.; Ali, Simi
Source: Self-asserted source
Steven Cobb via ResearcherID

Real time detection of cell cycle regulator cyclin A on living tumor cells with europium emission

Dalton Transactions
2013 | Journal article
DOI: 10.1039/c3dt51053k
WOSUID:

WOS:000323759600029
Contributors: Li, Hongguang; Chadbourne, Frances L.; Lan, Rongfeng; Chan, Chi-Fai; Chan, Wai-Lun; Law, Ga-Lai; Lee, Chi-Sing; Cobb, Steven L.; Wong, Ka-Leung
Source: Self-asserted source
Steven Cobb via ResearcherID

Synthesis of a novel tetrafluoropyridine-containing amino acid and tripeptide

Tetrahedron Letters
2013 | Journal article
DOI: 10.1016/j.tetlet.2013.06.124
WOSUID:

WOS:000323093300013
Contributors: Hudson, Alex S.; Hoose, Alex; Coxon, Christopher R.; Sandford, Graham; Cobb, Steven L.
Source: Self-asserted source
Steven Cobb via ResearcherID

Synthesis and molecular structure of a perfluorinated pyridyl carbanion

Journal of Fluorine Chemistry
2012 | Journal article
DOI: 10.1016/j.jfluchem.2011.09.013
WOSUID:

WOS:000300469500006
Contributors: Colgin, Neil; Tatum, Natalie J.; Pohl, Ehmke; Cobb, Steven L.; Sandford, Graham
Source: Self-asserted source
Steven Cobb via ResearcherID

Studies on the antileishmanial properties of the antimicrobial peptides temporin A, B and 1Sa

Journal of Peptide Science
2011 | Journal article
DOI: 10.1002/psc.1398
WOSUID:

WOS:000296493600006
Contributors: Chadbourne, Frances L.; Raleigh, Catriona; Ali, Hayder Z.; Denny, Paul W.; Cobb, Steven L.
Source: Self-asserted source
Steven Cobb via ResearcherID

Synthesis and properties of MIDA boronate containing aromatic amino acids: New peptide building blocks

Organic & Biomolecular Chemistry
2011 | Journal article
DOI: 10.1039/c0ob00847h
WOSUID:

WOS:000287931500026
Contributors: Colgin, Neil; Flinn, Tony; Cobb, Steven L.
Source: Self-asserted source
Steven Cobb via ResearcherID

Two-photon induced responsive f-f emissive detection of Cyclin A with a europium-chelating peptide

Chemical Communications
2011 | Journal article
DOI: 10.1039/c1cc12811f
WOSUID:

WOS:000293464100040
Contributors: Kong, Hoi-Kwan; Chadbourne, Frances L.; Law, Ga-Lai; Li, Hongguang; Tam, Hoi-Lam; Cobb, Steven L.; Lau, Chi-Kong; Lee, Chi-Sing; Wong, Ka-Leung
Source: Self-asserted source
Steven Cobb via ResearcherID

Antimicrobial peptides for leishmaniasis

Current Opinion in Investigational Drugs
2010 | Journal article
WOSUID:

WOS:000280192200002
Contributors: Cobb, Steven L.; Denny, Paul W.
Source: Self-asserted source
Steven Cobb via ResearcherID

F-19 NMR applications in chemical biology

Journal of Fluorine Chemistry
2009 | Journal article
DOI: 10.1016/j.jfluchem.2008.11.003
WOSUID:

WOS:000263940700001
Contributors: Cobb, Steven L.; Murphy, Cormac D.
Source: Self-asserted source
Steven Cobb via ResearcherID
Items per page:
Page 1 of 2

Peer review (32 reviews for 13 publications/grants)

Review activity for Accounts of chemical research. (1)
Review activity for ACS chemical biology. (1)
Review activity for ACS combinatorial science. (1)
Review activity for ACS infectious diseases. (1)
Review activity for ACS nano. (1)
Review activity for ACS omega. (1)
Review activity for Biochemistry. (1)
Review activity for Chemistry. (1)
Review activity for European journal of organic chemistry. (2)
Review activity for Journal of medicinal chemistry. (2)
Review activity for Journal of organic chemistry. (5)
Review activity for Journal of the American Chemical Society. (4)
Review activity for Organic letters. (11)
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