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Employment (4)

AstraZeneca FoU Göteborg: Gothenburg, SE

2020-06-01 to present | Senior Scientist (Discovery Sciences)
Employment
Source: Self-asserted source
Nicholas Holmes

University of Leeds: Leeds, GB

2018-05 to present | Research Fellow in Automated Flow Chemistry (School of Chemical & Process Engineering)
Employment
Source: Self-asserted source
Nicholas Holmes

GSK: Stevenage, GB

2018-05 to present | Research Fellow in Automated Flow Chemistry
Employment
Source: Self-asserted source
Nicholas Holmes

University of Leeds: Leeds, Leeds, GB

2012-09 to 2017-05 | PhD Student (School of Chemistry)
Employment
Source: Self-asserted source
Nicholas Holmes

Education and qualifications (3)

University of Leeds: Leeds, Leeds, GB

2012-09 to 2017-05 | PhD Chemistry/Chemical Engineering (Schools of Chemistry & Chemical Engineering)
Education
Source: Self-asserted source
Nicholas Holmes

University of Leeds: Leeds, GB

2012-09 to 2014-06 | MSc Chemical Process Technologies (Schools of Chemistry & Chemical Engineering)
Education
Source: Self-asserted source
Nicholas Holmes

University of Leicester: Leicester, Leicester, GB

2008-09 to 2012-06 | MChem Chemistry (Department of Chemistry)
Education
Source: Self-asserted source
Nicholas Holmes

Professional activities (1)

Royal Society of Chemistry: London, London, GB

2008 to present | MRSC
Membership
Source: Self-asserted source
Nicholas Holmes

Works (7)

Machine learning meets continuous flow chemistry: Automated optimization towards the Pareto front of multiple objectives

Chemical Engineering Journal
2018 | Journal article
DOI: https://doi.org/10.1016/j.cej.2018.07.031
Source: Self-asserted source
Nicholas Holmes

Enhanced process development using automated continuous reactors by self-optimisation algorithms and statistical empirical modelling

Tetrahedron
2018-02 | Journal article
DOI: 10.1016/j.tet.2018.02.061
Part of ISSN: 0040-4020
Contributors: Mohammed I. Jeraal; Nicholas Holmes; Geoffrey R. Akien; Richard A. Bourne
Source: Self-asserted source
Nicholas Holmes via Crossref Metadata Search

Rapid multistep kinetic model generation from transient flow data

React. Chem. Eng.
2017 | Journal article
DOI: 10.1039/c6re00109b
Part of ISSN: 2058-9883
Contributors: Christopher A. Hone; Nicholas Holmes; Geoffrey R. Akien; Richard A. Bourne; Frans L. Muller
Source: Self-asserted source
Nicholas Holmes via Crossref Metadata Search

Efficient and selective oxidation of sulfides in batch and continuous flow using styrene-based polymer immobilised ionic liquid phase supported peroxotungstates

RSC Advances
2016 | Journal article
DOI: 10.1039/c6ra11157b
Part of ISSN: 2046-2069
Contributors: S. Doherty; J. G. Knight; M. A. Carroll; A. R. Clemmet; J. R. Ellison; T. Backhouse; N. Holmes; L. A. Thompson; R. A. Bourne
Source: Self-asserted source
Nicholas Holmes via Crossref Metadata Search

Online quantitative mass spectrometry for the rapid adaptive optimisation of automated flow reactors

React. Chem. Eng.
2016 | Journal article
DOI: 10.1039/c5re00083a
Contributors: Nicholas Holmes; Geoffrey R. Akien; Robert J. D. Savage; Christian Stanetty; Ian R. Baxendale; A. John Blacker; Brian A. Taylor; Robert L. Woodward; Rebecca E. Meadows; Richard A. Bourne
Source: Self-asserted source
Nicholas Holmes via Crossref Metadata Search

Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor

React. Chem. Eng.
2016 | Journal article
DOI: 10.1039/c6re00059b
Contributors: Nicholas Holmes; Geoffrey R. Akien; A. John Blacker; Robert L. Woodward; Rebecca E. Meadows; Richard A. Bourne
Source: Self-asserted source
Nicholas Holmes via Crossref Metadata Search

Self-​optimizing flow reactors in pharmaceutical development for rapid process optimization

ACS National Meeting & Exposition, San Diego, CA
2016-03 | Conference abstract
Source: Self-asserted source
Nicholas Holmes
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