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germarium, germ cells, Drosophila, meiosis, abscission, cytokinesis, non-coding RNA, gametogenesis, stem cells
France

Activities

Employment (4)

Collège de France: Paris, Île-de-France, FR

2017-09-15 to present | Senior Group Leader (CIRB)
Employment
Source: Self-asserted source
Jean-René HUYNH

Institut Curie: Paris, Île-de-France, FR

2014 to 2017 | Senior Group Leader (Genetics and Developmental Biology)
Employment
Source: Self-asserted source
Jean-René HUYNH

Institut Curie: Paris, Île-de-France, FR

2009 to 2014 | Junior Group Leader (Genetics and Developmental Biology)
Employment
Source: Self-asserted source
Jean-René HUYNH

Institut Jacques Monod: Paris, Île-de-France, FR

2005 to 2008 | CR CNRS (Developmental Biology)
Employment
Source: Self-asserted source
Jean-René HUYNH

Education and qualifications (3)

Institut Jacques Monod: Paris, Île-de-France, FR

2003 to 2005 | Post-Doc (Jean-Antoine Lepesant)
Education
Source: Self-asserted source
Jean-René HUYNH

University of Cambridge: Cambridge, Cambridgeshire, GB

1998 to 2002 | PhD (Welcome/Trust Daniel St Johnston)
Education
Source: Self-asserted source
Jean-René HUYNH

Ecole Normale Supérieure: Paris, Paris, FR

1995 to 1999 | Graduate Student (Biology)
Education
Source: Self-asserted source
Jean-René HUYNH

Professional activities (2)

CNRS Délégation Paris B: Paris, Île-de-France, FR

2014 to present | DR
Invited position
Source: Self-asserted source
Jean-René HUYNH

CNRS Délégation Paris B: Paris, Île-de-France, FR

2005 to 2014 | CR
Invited position
Source: Self-asserted source
Jean-René HUYNH

Works (40)

Conserved meiotic mechanisms in the cnidarian Clytia hemisphaerica revealed by Spo11 knockout

Science Advances
2023-01-27 | Journal article | Author
Part of ISSN: 2375-2548
Contributors: Catriona Munro; Hugo Cadis; Sophie Pagnotta; Evelyn Houliston; Jean-René HUYNH
Source: Self-asserted source
Jean-René HUYNH

Premeiotic pairing of homologous chromosomes during <i>Drosophila</i> male meiosis

Proceedings of the National Academy of Sciences
2022-11-22 | Journal article | Author
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Contributors: thomas rubin; Nicolas Macaisne; Ana Maria Vallés; Clara Guilleman; Gaugué Isabelle; Laurine Dal Toe; Jean-René HUYNH
Source: Self-asserted source
Jean-René HUYNH

Cytoplasmic forces functionally reorganize nuclear condensates in oocytes

Nature Communications
2022-08-29 | Journal article | Author
Part of ISSN: 2041-1723
Contributors: Adel Al Jord; Gaëlle Letort; soline chanet; Feng-Ching Tsai; Christophe Antoniewski; Adrien Eichmuller; Christelle Da Silva; Jean-René HUYNH; NIR GOV; Raphaël Voituriez et al.
Source: Self-asserted source
Jean-René HUYNH

The deubiquitinase USP8 targets ESCRT-III to promote incomplete cell division

Science
2022-05-20 | Journal article | Author
Part of ISSN: 0036-8075
Part of ISSN: 1095-9203
Contributors: Juliette Mathieu; Pascale Michel-Hissier; virginie boucherit; Jean-René HUYNH
Source: Self-asserted source
Jean-René HUYNH

tRNA Fragments Populations Analysis in Mutants Affecting tRNAs Processing and tRNA Methylation.

Frontiers in genetics
2020-10 | Journal article
Contributors: Molla-Herman A; Angelova MT; Ginestet M; Carré C; Antoniewski C; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Collective Cell Sorting Requires Contractile Cortical Waves in Germline Cells.

Current biology : CB
2020-09 | Journal article
Contributors: Chanet S; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Mixing and Matching Chromosomes during Female Meiosis

Cells
2020-03 | Journal article | Author
Contributors: Thomas Rubin; Nicolas Macaisne; Jean-René HUYNH
Source: check_circle
Multidisciplinary Digital Publishing Institute

Isolation of stage-specific germ cells using FACS in Drosophila germarium.

Methods in cell biology
2020-02 | Journal article
Contributors: Vallés AM; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Collective cell sorting requires contractile cortical waves in germline cells

2020-01 | Preprint
OTHER-ID:

PPR107718

Contributors: Chanet S; Huynh J
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

tRNA fragments (tRFs) populations analysis in mutants affecting tRNAs processing and tRNA methylation

2019-12 | Preprint
OTHER-ID:

PPR105150

Contributors: Molla-Herman A; Angelova M; Carré C; Antoniewski C; Huynh J
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Centromeric SMC1 promotes centromere clustering and stabilizes meiotic homolog pairing.

PLoS genetics
2019-10 | Journal article
Contributors: Hatkevich T; Boudreau V; Rubin T; Maddox PS; Huynh JR; Sekelsky J
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Centromere clustering stabilizes meiotic homolog pairing

2019-04 | Preprint
OTHER-ID:

PPR76592

Contributors: Hatkevich T; Boudreau V; Rubin T; Maddox PS; Huynh J; Sekelsky J
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

The replicative histone chaperone CAF1 is essential for the maintenance of identity and genome integrity in adult stem cells.

Development (Cambridge, England)
2018-08 | Journal article
Contributors: Clémot M; Molla-Herman A; Mathieu J; Huynh JR; Dostatni N
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Bam and Otu can regulate stem cell fate by stabilizing cyclin A.

Proceedings of the National Academy of Sciences of the United States of America
2017-06 | Journal article
Contributors: Mathieu J; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Monitoring complete and incomplete abscission in the germ line stem cell lineage of Drosophila ovaries.

Methods in cell biology
2016-05 | Journal article
Contributors: Mathieu J; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

How to pre-pair chromosomes for meiosis.

Cell cycle (Georgetown, Tex.)
2016-01 | Journal article
Contributors: Rubin T; Christophorou N; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Microtubule-driven nuclear rotations promote meiotic chromosome dynamics.

Nature cell biology
2015-10 | Journal article
Contributors: Christophorou N; Rubin T; Bonnet I; Piolot T; Arnaud M; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription.

The EMBO journal
2015-10 | Journal article
Contributors: Molla-Herman A; Vallés AM; Ganem-Elbaz C; Antoniewski C; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Abscission is regulated by the ESCRT-III protein shrub in Drosophila germline stem cells.

PLoS genetics
2015-02 | Journal article
Contributors: Matias NR; Mathieu J; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo.

PLoS genetics
2015-01 | Journal article
Contributors: Eikenes ÅH; Malerød L; Christensen AL; Steen CB; Mathieu J; Nezis IP; Liestøl K; Huynh JR; Stenmark H; Haglund K
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Mosaic Analysis in the Drosophila melanogaster Ovary.

Methods in molecular biology (Clifton, N.J.)
2015-01 | Journal article
Contributors: Rubin T; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Chromatin modifications regulate germ cell development and transgenerational information relay.

Current opinion in insect science
2014-05 | Journal article
Contributors: Molla-Herman A; Matias NR; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

EMS mutagenesis in the pea aphid Acyrthosiphon pisum.

G3 (Bethesda, Md.)
2014-04 | Journal article
Contributors: Tagu D; Le Trionnaire G; Tanguy S; Gauthier JP; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Synaptonemal complex components promote centromere pairing in pre-meiotic germ cells.

PLoS genetics
2013-12 | Journal article
Contributors: Christophorou N; Rubin T; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Aurora B and cyclin B have opposite effects on the timing of cytokinesis abscission in Drosophila germ cells and in vertebrate somatic cells.

Developmental cell
2013-08 | Journal article
Contributors: Mathieu J; Cauvin C; Moch C; Radford SJ; Sampaio P; Perdigoto CN; Schweisguth F; Bardin AJ; Sunkel CE; McKim K et al.
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

A mosaic genetic screen for genes involved in the early steps of Drosophila oogenesis.

G3 (Bethesda, Md.)
2013-03 | Journal article
Contributors: Jagut M; Mihaila-Bodart L; Molla-Herman A; Alin MF; Lepesant JA; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

lethal giant larvae is required with the par genes for the early polarization of the Drosophila oocyte.

Development (Cambridge, England)
2010-03 | Journal article
Contributors: Fichelson P; Jagut M; Lepanse S; Lepesant JA; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

[Asymetric growth in Drosophila stem cells is related to ribosomal biogenesis].

Medecine sciences : M/S
2009-10 | Journal article
Contributors: Fichelson P; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Live-imaging of single stem cells within their niche reveals that a U3snoRNP component segregates asymmetrically and is required for self-renewal in Drosophila.

Nature cell biology
2009-05 | Journal article
Contributors: Fichelson P; Moch C; Ivanovitch K; Martin C; Sidor CM; Lepesant JA; Bellaiche Y; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

[Regulation of germline stem cells: the niche expands in Drosophila].

Medecine sciences : M/S
2007-06 | Journal article
Contributors: Jagut M; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

[Genetic control of intercellular adhesion or how cadherins shape the fruitfly Drosophila melanogaster].

Medecine sciences : M/S
2007-03 | Journal article
Contributors: Bécam I; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Asymmetric divisions of germline cells.

Progress in molecular and subcellular biology
2007-01 | Journal article
Contributors: Fichelson P; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila.

Nature cell biology
2005-04 | Journal article
Contributors: Bécam IE; Tanentzapf G; Lepesant JA; Brown NH; Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

The origin of asymmetry: early polarisation of the Drosophila germline cyst and oocyte.

Current biology : CB
2004-06 | Journal article
Contributors: Huynh JR; St Johnston D
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

The Drosophila hnRNPA/B homolog, Hrp48, is specifically required for a distinct step in osk mRNA localization.

Developmental cell
2004-05 | Journal article
Contributors: Huynh JR; Munro TP; Smith-Litière K; Lepesant JA; St Johnston D
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

[Cell polarity and oocyte determination in Drosophila melanogaster].

Journal de la Societe de biologie
2003-01 | Journal article
Contributors: Huynh JR
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Bazooka and PAR-6 are required with PAR-1 for the maintenance of oocyte fate in Drosophila.

Current biology : CB
2001-06 | Journal article
Contributors: Huynh JR; Petronczki M; Knoblich JA; St Johnston D
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Centrosome migration into the Drosophila oocyte is independent of BicD and egl, and of the organisation of the microtubule cytoskeleton.

Development (Cambridge, England)
2001-05 | Journal article
Contributors: Bolívar J; Huynh JR; López-Schier H; González C; St Johnston D; González-Reyes A
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

PAR-1 is required for the maintenance of oocyte fate in Drosophila.

Development (Cambridge, England)
2001-04 | Journal article
Contributors: Huynh JR; Shulman JM; Benton R; St Johnston D
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

The role of BicD, Egl, Orb and the microtubules in the restriction of meiosis to the Drosophila oocyte.

Development (Cambridge, England)
2000-07 | Journal article
Contributors: Huynh JR; St Johnston D
Source: Self-asserted source
Jean-René HUYNH via Europe PubMed Central

Peer review (10 reviews for 5 publications/grants)

Review activity for Life science alliance. (1)
Review activity for Nature communications (2)
Review activity for PLoS biology. (3)
Review activity for PLOS genetics. (3)
Review activity for Review Commons (1)