Personal information

United Kingdom

Activities

Employment (6)

National University of Singapore: Singapore, SG

2022-01-03 to present | Research Professor (Department of Medicine)
Employment
Source: Self-asserted source
Shu Ye

University of Leicester: Leicester, Leicester, GB

2015-05-01 to 2022-01-10 | Professor of Cardiovascular Molecular Medicine and Genetics (Department of Cardiovascular Sciences)
Employment
Source: Self-asserted source
Shu Ye

Queen Mary University of London Barts and The London School of Medicine and Dentistry: London, London, GB

2006-04-19 to 2015-04-30 | Professor of Molecular Medicine and Genetics (William Harvey Research Institute)
Employment
Source: Self-asserted source
Shu Ye

University of Southampton Faculty of Medicine: Southampton, Southampton, GB

1998-11-01 to 2006-04-18 | Senior Lecturer (Human Genetics Division)
Employment
Source: Self-asserted source
Shu Ye

University of Oxford: Oxford, Oxfordshire, GB

1996-01-01 to 1998-10-31 | British Heart Foundation Research Fellow (Department of Cardiovascular Medicine)
Employment
Source: Self-asserted source
Shu Ye

University College London: London, London, GB

1990-10-01 to 1995-12-31 | Research Fellow (Department of Medicine)
Employment
Source: Self-asserted source
Shu Ye

Education and qualifications (6)

Higher Education Academy: London, GB

2017-03-01 to present | Fellow of The Higher Education Academy
Qualification
Source: Self-asserted source
Shu Ye

The Royal College of Pathologists: London, London, GB

2008-01-01 to present | Fellow of the Royal College of Pathologists
Qualification
Source: Self-asserted source
Shu Ye

The Royal College of Pathologists: London, London, GB

2005-11-03 to 2007-12-31 | Member of the Royal College of Pathologists.
Qualification
Source: Self-asserted source
Shu Ye

University College London: London, London, GB

1992 to 1996 | PhD
Education
Source: Self-asserted source
Shu Ye

Sun Yat-Sen University of Medical Sciences: Guangzhou, Guangdong, CN

1986 to 1990 | MD
Education
Source: Self-asserted source
Shu Ye

Shantou University Medical College: Shantou, CN

1978 to 1983
Education
Source: Self-asserted source
Shu Ye

Funding (19)

BHF 4-year PhD Studentship Programme (2021 - 2024 intakes) - University of Leicester

2021-09 to 2028-08 | Grant
British Heart Foundation (London, GB)
GRANT_NUMBER:

FS/4yPhD/P/20/34013

Source: Self-asserted source
Shu Ye

Mechanistic investigation of the effect of Ang II on vascular smooth muscle cell proliferation/migration and atherosclerosis via the lncRNA RP4-639F20.1/THRAP3 pathway.

2021-01 to 2024-12 | Grant
National Natural Science Foundation of China (Beijing, CN)
GRANT_NUMBER:

82070466

Source: Self-asserted source
Shu Ye

Genetic discovery-based targeting of the vascular interface in atherosclerosis (joint funding with DZHK)

2019-09-01 to 2023-08-31 | Grant
British Heart Foundation (London, GB)
GRANT_NUMBER:

BHF-SP/19/2/34462

Source: Self-asserted source
Shu Ye
grade
Preferred source (of 2)‎

A comprehensive study to uncover and understand genetic influences on vascular smooth muscle cell behaviour in relation to cardiovascular diseases

2017-05-08 to 2020-05-07 | Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: RG/16/13/32609
Source: Self-asserted source
Shu Ye via DimensionsWizard

Functional study of coronary heart disease-associated polymorphisms at the COL4A1/COL4A2 locus.

2013 to 2017 | Grant
National Natural Science Foundation of China (Beijing, CN)
GRANT_NUMBER:

81370202

Source: Self-asserted source
Shu Ye

Analyses of matrix metalloproteinase-12 gene variations in relation to myocardial infraction susceptibility

2008-01-21 to 2011-01-20 | Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: FS/07/021/22945
Source: Self-asserted source
Shu Ye via DimensionsWizard

Genetic influence on progression and severity of coronary heart disease and restenosis after angioplasty: the Southampton atherosclerosis study (SAS).

1999 to 2002 | Grant
British Heart Foundation (London, GB)
GRANT_NUMBER:

PG/1998183/11145

Source: Self-asserted source
Shu Ye

Variation in the stromelysin gene in relation to coronary heart disease.

1999 to 2002 | Grant
British Heart Foundation (London, GB)
GRANT_NUMBER:

PG/1998192/11171

Source: Self-asserted source
Shu Ye

Variation in the human stromelysin gene promoter and its effect on the control of expression.

1996-01 to 1998-12 | Grant
British Heart Foundation (London, GB)
GRANT_NUMBER:

FS/1995011/8212

Source: Self-asserted source
Shu Ye

A comprehensive study to uncover and understand genetic influences on vascular smooth muscle cell behaviour in relation to cardiovascular diseases (renewal)

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: RG/19/9/34655
Source: Self-asserted source
Shu Ye via DimensionsWizard

A functional mechanistic study of genetic variants at the coronary artery disease susceptibility locus on chromosome 10q11

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: PG/18/73/34059
Source: Self-asserted source
Shu Ye via DimensionsWizard

Functional analyses of coronary artery disease-related genetic variant at the FURIN locus

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: PG/16/9/31995
Source: Self-asserted source
Shu Ye via DimensionsWizard

Functional analyses of the MMP3 gene 5T/6T polymorphism that is associated with progression and complications of atherosclerosis

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: PG/05/093/19531
Source: Self-asserted source
Shu Ye via DimensionsWizard

Matrix metalloproteinase-8 in the pathogenesis of atherosclerosis

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: PG/08/051/25141
Source: Self-asserted source
Shu Ye via DimensionsWizard

Molecular genetic and functional analyses of ABCA 1 gene variants

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: PG/02/053/13765
Source: Self-asserted source
Shu Ye via DimensionsWizard

Molecular genetic and functional analysis of TLR4 gene variants

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: PG/05/039/18669
Source: Self-asserted source
Shu Ye via DimensionsWizard

Regulation of matrix metalloproteinase-14 expression by hypoxia-inducible transcription factor - implications in neovessel formation in atherosclerotic plaques

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: FS/11/28/28758
Source: Self-asserted source
Shu Ye via DimensionsWizard

SLC4A7 and the electroneutral sodium-bicarbonate cotransporter NBCn1: Characterisation of a candidate gene in hypertension

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: FS/12/82/29736
Source: Self-asserted source
Shu Ye via DimensionsWizard

Variation in the matrix metalloproteinase-1 gene in relation to atherosclerosis

Grant
British Heart Foundation (London, GB)
GRANT_NUMBER: PG/2001105/13047
Source: Self-asserted source
Shu Ye via DimensionsWizard

Works (50 of 160)

Items per page:
Page 1 of 4

Genetic influence on vascular smooth muscle cell apoptosis.

Cell death & disease
2024-06-08 | Journal article | Author
Contributors: David Graham McVey; Andreadi C; Gong P; Stanczyk PJ; Solomon CU; Turner L; Yan L; Chen R; Cao J; Nelson CP et al.
Source: Self-asserted source
Shu Ye

Network-based prioritization and validation of regulators of vascular smooth muscle cell proliferation in disease

Nature Cardiovascular Research
2024-06-06 | Journal article
Part of ISSN: 2731-0590
Contributors: Jordi Lambert; Sebnem Oc; Matthew Worssam; Daniel Häußler; Charles U. Solomon; Nichola L. Figg; Ruby Baxter; Maria Imaz; James C. K. Taylor; Kirsty Foote et al.
Source: Self-asserted source
Shu Ye

Pyroptosis of Vascular Smooth Muscle Cells as a Potential New Target for Preventing Vascular Diseases.

Cardiovascular drugs and therapy
2024-06-01 | Journal article
Contributors: Di C; Ji M; Li W; Liu X; Gurung R; Qin B; Ye S; Rong Qi
Source: Self-asserted source
Shu Ye

Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in psoriasis: a systematic review and meta-analysis.

Archives of dermatological research
2024-02-08 | Journal article
Contributors: Ye JH; Zhang Y; Naidoo K; Ye S
Source: Self-asserted source
Shu Ye

Phenotypic Switching of Vascular Smooth Muscle Cells in Atherosclerosis

Journal of the American Heart Association
2023-10-17 | Journal article
Contributors: Runji Chen; David G. McVey; Daifei Shen; Xiaoxin Huang; Shu Ye
Source: check_circle
Crossref

Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity.

Journal of translational medicine
2023-10-16 | Journal article
Contributors: Tan CY; Chan PS; Tan H; Tan SW; Lee CJM; Wang JW; Ye S; Werner H; Loh YJ; Lee YL et al.
Source: Self-asserted source
Shu Ye

Effector Genes at the Coronary Artery Disease Risk Locus Harboring PDGFD and LncRNA AP002989.1

Journal of the American Heart Association
2023-08 | Journal article
Contributors: Charles U. Solomon; Wei Yang; Shu Ye
Source: check_circle
Crossref

LncRNA RP4-639F20.1 interacts with THRAP3 to attenuate atherosclerosis by regulating c-FOS in vascular smooth muscle cells proliferation and migration.

Atherosclerosis
2023-07-08 | Journal article
Contributors: Zhang R; Bu F; Wang Y; Huang M; Lin X; Wu C; Chen J; Huang Y; Wang H; Ye S et al.
Source: Self-asserted source
Shu Ye

Allele-Specific Epigenetic Regulation of <i>FURIN</i> Expression at a Coronary Artery Disease Susceptibility Locus

Cells
2023-06 | Journal article | Author
Contributors: Wei Yang; Junjun Cao; David Graham McVey; Shu Ye
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Effect of probiotic supplementation on in-hospital mortality in patients with acute myocardial infarction: a study protocol for an open-label, randomized, controlled, superiority clinical trial.

Trials
2023-06-24 | Journal article
Contributors: Chen Y; Chen R; Wang X; Zhou Y; Hong L; Xiong N; Zhu J; Ye S; Xuerui Tan
Source: Self-asserted source
Shu Ye
grade
Preferred source (of 2)‎

LncRNA NIPA1-SO confers atherosclerotic protection by suppressing the transmembrane protein NIPA1.

Journal of advanced research
2023-01-31 | Journal article
Contributors: Jiang M; Song Y; Ren MX; He RC; Dong XH; Li XH; Lu ZF; Li S; Wu J; Bei YR et al.
Source: Self-asserted source
Shu Ye
grade
Preferred source (of 2)‎

Nociceptin/Orphanin FQ receptor expression in primary human umbilical vein endothelial cells is not regulated by exposure to breast cancer cell media or angiogenic stimuli

BJA Open
2022-12 | Journal article
Part of ISSN: 2772-6096
Contributors: Despina Giakomidi; Sonja Khemiri; Wadhah Mahbuba; David G. McVey; Fatin Al-Janabi; Remo Guerrini; Girolamo Calo; Shu Ye; David G. Lambert
Source: Self-asserted source
Shu Ye

The <i>FES</i> Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis.

Circulation research
2022-11-02 | Journal article | Author
Contributors: Karamanavi E; David Graham McVey; Sander W. van der Laan; Stanczyk PJ; Morris GE; Yifan Wang; Yang W; Kenneth Chan; Poston RN; Luo J et al.
Source: Self-asserted source
Shu Ye

In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells.

PloS one
2022-09-15 | Journal article
Contributors: Bird MF; Gallacher-Horley B; McDonald J; McVey DG; Al-Janabi F; Guerrini R; Calo G; Ye S; Thompson JP; David Lambert
Source: Self-asserted source
Shu Ye

Effects of Coronary Artery Disease-Associated Variants on Vascular Smooth Muscle Cells.

Circulation
2022-06-23 | Journal article
Source: Self-asserted source
Shu Ye

Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.

Nature communications
2022-03-09 | Journal article
Source: Self-asserted source
Shu Ye

Association of Impaired Fasting Blood Glucose With Triple Coronary Artery Stenosis and Myocardial Infarction Among Patients With Coronary Artery Stenosis

Frontiers in Cell and Developmental Biology
2022-03-03 | Journal article
Part of ISSN: 2296-634X
Source: Self-asserted source
Shu Ye

Association of uterine fibroids with increased blood pressure: a cross-sectional study and meta-analysis.

Hypertension research : official journal of the Japanese Society of Hypertension
2022-02-15 | Journal article
Source: Self-asserted source
Shu Ye

Relationship between red meat metabolite trimethylamine N-oxide and cardiovascular disease

Heart and Mind
2022-01 | Journal article
Part of ISSN: 2468-6476
Contributors: Shu Ye; Angatu Yousuf; DavidG McVey
Source: Self-asserted source
Shu Ye

Efficiency of atorvastatin on in-hospital mortality of patients with acute aortic dissection (AAD): study protocol for a randomized, open-label, superiority clinical trial.

Trials
2021-04 | Journal article
Contributors: Chen Y; Xiong N; Wang X; Wu S; Hong L; Huang X; Chen C; Li W; Wang B; Ye S et al.
Source: Self-asserted source
Shu Ye via Europe PubMed Central

The Long Noncoding RNA RP11-728F11.4 Promotes Atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology
2021-01-06 | Journal article
Source: Self-asserted source
Shu Ye

Non-O blood group is associated with lower risk of in-hospital mortality in non-surgically managed patients with type A aortic dissection.

BMC cardiovascular disorders
2020-12-09 | Journal article
Source: Self-asserted source
Shu Ye

Genetic Associations with Plasma ACE2 Concentration: Potential Relevance to COVID-19 Risk.

Circulation
2020-07 | Journal article
Contributors: Nelson CP; Sama IE; Codd V; Webb TR; Ye S; Lang CC; Voors AA; Ng LL; Samani NJ
Source: Self-asserted source
Shu Ye via Europe PubMed Central

FURIN Expression in Vascular Endothelial Cells Is Modulated by a Coronary Artery Disease-Associated Genetic Variant and Influences Monocyte Transendothelial Migration.

Journal of the American Heart Association
2020-02-11 | Journal article
Source: Self-asserted source
Shu Ye

Effect of a coronary-heart-disease-associated variant of ADAMTS7 on endothelial cell angiogenesis

Atherosclerosis
2020-01 | Journal article
Source: check_circle
Researchfish

Microarray profiling analysis and validation of novel long noncoding RNAs and mRNAs as potential biomarkers and their functions in atherosclerosis.

Physiological genomics
2019-11-04 | Journal article
Source: Self-asserted source
Shu Ye

HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis.

Circulation
2019-06-05 | Journal article
Source: Self-asserted source
Shu Ye

Genetic Assessment of Potential Long-Term On-Target Side Effects of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Inhibitors.

Circulation. Genomic and precision medicine
2019-01 | Journal article
Contributors: Nelson CP; Lai FY; Nath M; Ye S; Webb TR; Schunkert H; Samani NJ
Source: Self-asserted source
Shu Ye via Europe PubMed Central

The role of the LncRNA-FA2H-2-MLKL pathway in atherosclerosis by regulation of autophagy flux and inflammation through mTOR-dependent signaling.

Cell death and differentiation
2019-01 | Journal article
Contributors: Guo FX; Wu Q; Li P; Zheng L; Ye S; Dai XY; Kang CM; Lu JB; Xu BM; Xu YJ et al.
Source: Self-asserted source
Shu Ye via Europe PubMed Central

Long non-coding RNA NEXN-AS1 mitigates atherosclerosis by regulating the actin-binding protein NEXN.

The Journal of clinical investigation
2018-12 | Journal article
Contributors: Hu YW; Guo FX; Xu YJ; Li P; Lu ZF; McVey DG; Zheng L; Wang Q; Ye JH; Kang CM et al.
Source: Self-asserted source
Shu Ye via Europe PubMed Central
grade
Preferred source (of 2)‎

Propofol Suppresses Proinflammatory Cytokine Production by Increasing ABCA1 Expression via Mediation by the Long Noncoding RNA LOC286367.

Mediators of inflammation
2018-12 | Journal article
Contributors: Ma X; Wang T; Zhao ZL; Jiang Y; Ye S
Source: Self-asserted source
Shu Ye via Europe PubMed Central
grade
Preferred source (of 2)‎

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention.

Journal of the American College of Cardiology
2018-10 | Journal article
Contributors: Inouye M; Abraham G; Nelson CP; Wood AM; Sweeting MJ; Dudbridge F; Lai FY; Kaptoge S; Brozynska M; Wang T et al.
Source: Self-asserted source
Shu Ye via Europe PubMed Central

Influence of a Coronary Artery Disease-Associated Genetic Variant on FURIN Expression and Effect of Furin on Macrophage Behavior.

Arteriosclerosis, thrombosis, and vascular biology
2018-07 | Journal article
Contributors: Zhao G; Yang W; Wu J; Chen B; Yang X; Chen J; McVey DG; Andreadi C; Gong P; Webb TR et al.
Source: Self-asserted source
Shu Ye via Europe PubMed Central
grade
Preferred source (of 2)‎

Subcutaneous Injection of Nitroglycerin at the Radial Artery Puncture Site Reduces the Risk of Early Radial Artery Occlusion After Transradial Coronary Catheterization: A Randomized, Placebo-Controlled Clinical Trial.

Circulation. Cardiovascular interventions
2018-07 | Journal article
Contributors: Chen Y; Ke Z; Xiao J; Lin M; Huang X; Yan C; Ye S; Tan X
Source: Self-asserted source
Shu Ye via Europe PubMed Central
grade
Preferred source (of 2)‎

JCAD Gene at the 10p11 Coronary Artery Disease Locus Regulates Hippo Signaling in Endothelial Cells.

Arteriosclerosis, thrombosis, and vascular biology
2018-05 | Journal article
Contributors: Jones PD; Kaiser MA; Ghaderi Najafabadi M; Koplev S; Zhao Y; Douglas G; Kyriakou T; Andrews S; Rajmohan R; Watkins H et al.
Source: Self-asserted source
Shu Ye via Europe PubMed Central

Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis.

Journal of the American Heart Association
2018-02 | Journal article
Contributors: Wen G; An W; Chen J; Maguire EM; Chen Q; Yang F; Pearce SWA; Kyriakides M; Zhang L; Ye S et al.
Source: Self-asserted source
Shu Ye via Europe PubMed Central

Increased NBCn1 expression, Na+/HCO3- co-transport and intracellular pH in human vascular smooth muscle cells with a risk allele for hypertension.

Human molecular genetics
2017 | Journal article
Source: Self-asserted source
Shu Ye

Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease.

Journal of the American Heart Association
2017-10 | Journal article
Source: Self-asserted source
Shu Ye via Europe PubMed Central

The biological impact of blood pressure associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle.

Human molecular genetics
2017-10 | Journal article
Source: Self-asserted source
Shu Ye via Europe PubMed Central
grade
Preferred source (of 2)‎

A blood pressure-associated variant of the SLC39A8 gene influences cellular cadmium accumulation and toxicity.

Human molecular genetics
2016 | Journal article
Source: Self-asserted source
Shu Ye

Association of MicroRNAs and YRNAs With Platelet Function

CIRCULATION RESEARCH
2016 | Journal article
Source: Self-asserted source
Shu Ye

Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction

PLOS GENETICS
2016 | Journal article
Source: Self-asserted source
Shu Ye

Difference in Leukocyte composition between women before and after menopausal age, and distinct sexual dimorphism

PLoS ONE
2016 | Journal article
Source: Self-asserted source
Shu Ye

A Novel Role of Matrix Metalloproteinase-8 in Macrophage Differentiation and Polarization

JOURNAL OF BIOLOGICAL CHEMISTRY
2015 | Journal article
Source: Self-asserted source
Shu Ye

Effect of genetic polymorphisms involved in folate metabolism on the concentration of serum folate and plasma total homocysteine (p-tHcy) in healthy subjects after short-term folic acid supplementation: a randomized, double blind, crossover study

GENES AND NUTRITION
2015 | Journal article
Source: Self-asserted source
Shu Ye

Effects of polymorphisms in endothelial nitric oxide synthase and folate metabolizing genes on the concentration of serum nitrate, folate, and plasma total homocysteine after folic acid supplementation: A double-blind crossover study

NUTRITION
2015 | Journal article
Source: Self-asserted source
Shu Ye

MicroRNA-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells by Targeting Methyl CpG-Binding Protein 2

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
2015 | Journal article
Source: Self-asserted source
Shu Ye

Putative targeting of matrix metalloproteinase-8 in atherosclerosis

PHARMACOLOGY & THERAPEUTICS
2015 | Journal article
Source: Self-asserted source
Shu Ye

Upregulated sirtuin 1 by miRNA-34a is required for smooth muscle cell differentiation from pluripotent stem cells

CELL DEATH AND DIFFERENTIATION
2015 | Journal article
Source: Self-asserted source
Shu Ye

A simple high-performance liquid chromatography (HPLC) method for the measurement of pyridoxal-5-phosphate and 4-pyridoxic acid in human plasma

CLINICA CHIMICA ACTA
2014 | Journal article
Source: Self-asserted source
Shu Ye
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Peer review (2 reviews for 2 publications/grants)

Review activity for European journal of preventive cardiology. (1)
Review activity for Signal transduction and targeted therapy. (1)