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Scopus Author ID: 35372982200
Scopus Author ID: 35372982200

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Microbiology

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United Kingdom

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Employment (3)

University Of Strathclyde: Glasgow, GB

Employment
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University of Strathclyde

University of Strathclyde: Glasgow, Glasogw, GB

2022-10-03 to present | Professor (Strathclyde Institute of Pharmacy & Biomedical Sciences)
Employment
Source: Self-asserted source
Daniel Walker

University of Glasgow: Glasgow, Glasgow, GB

2007-08-01 to 2022-10-02 | Professor (Institute of Infection, Immunity and Inflammation)
Employment
Source: Self-asserted source
Daniel Walker

Funding (5)

Protein Antibiotics: Discovery, mode of action and development

2016-08-01 to 2021-07-31 | Grant
Wellcome Trust (London, GB)
URL: https://grants.uberresearch.com/100004440/201505%252FZ%252F16%252FZ/Protein-Antibiotics-Discovery-mode-of-action-and-development
GRANT_NUMBER:

grant.201505/Z/16/Z
Source: Self-asserted source
Daniel Walker via DimensionsWizard

Protein antibiotics for the treatment of Pseudomonas aeruginosa lung infection

Source: Self-asserted source
Daniel Walker via DimensionsWizard

Where and Why: The Influence of Host Metabolism on Bacterial Niche Specificity

2016-03-01 to 2019-02-28 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://grants.uberresearch.com/501100000268/85574924-D79F-45A4-B153-864178EFA566/Where-and-Why-The-Influence-of-Host-Metabolism-on-Bacterial-Niche-Specificity
GRANT_NUMBER: BB/M029646/1
Source: Self-asserted source
Daniel Walker via DimensionsWizard

A novel mechanism of protein uptake in Gram-negative bacteria

2014-08-31 to 2017-08-30 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
URL: https://grants.uberresearch.com/501100000268/820C3125-C9A2-441D-9AFD-9B985A2BE216/A-novel-mechanism-of-protein-uptake-in-Gram-negative-bacteria
GRANT_NUMBER: BB/L02022X/1
Source: Self-asserted source
Daniel Walker via DimensionsWizard

Characterisation of YtfM: a conserved protein implicated in outer membrane biogenesis in Gram-negative bacteria

Source: Self-asserted source
Daniel Walker via DimensionsWizard

Works (50 of 52)

Items per page:
Page 1 of 2

Identification and functional analysis of novel SNPs in enterocin genes of Enterococcus faecium GHB21

Probiotics and antimicrobial proteins
2025-02-28 | Journal article | Author
DOI: 10.1007/s12602-025-10488-4
SOURCE-WORK-ID:

c489682d-b562-4019-87f3-dc4465876d5a

PMID: 40019734
EID:

2-s2.0-85219049953
Contributors: Mohamed Merzoug; Khédidja Mosbahi; Daniel Walker; Nour Eddine Karam; Zohra Yasmine Zater; Svetoslav Dimitrov Todorov; Djamal Saidi
Source: check_circle
University of Strathclyde

Stratifying macrophages based on their infectious burden identifies novel host targets for intervention during Crohn’s disease associated adherent-invasive Escherichia coli infection

Microbiology
2024-06-25 | Journal article | Author
DOI: 10.1099/mic.0.001470
SOURCE-WORK-ID:

c9a474a4-90ff-424d-8260-d0ebc6637e73

EID:

2-s2.0-85196984456
Contributors: Xiang Li; John Cole; Diane Vaughan; Yinbo Xiao; Daniel Walker; Daniel m. Wall
Source: check_circle
University of Strathclyde

Letter: The multifaceted role of Escherichia coli in influencing disorders of the industrial populations-Authors' reply

Alimentary Pharmacology and Therapeutics
2024-03 | Journal article | Author
DOI: 10.1111/apt.17883
SOURCE-WORK-ID:

9055a5e2-5012-4d35-84e0-61085aeff936

EID:

2-s2.0-85184721517

PMID: 38349700
Contributors: Konstantinos Gerasimidis; Nojoud Faqerah; Daniel Walker
Source: check_circle
University of Strathclyde

Review article: The complex interplay between diet and Escherichia coli in inflammatory bowel disease

Alimentary Pharmacology & Therapeutics
2023-11 | Journal article
DOI: 10.1111/apt.17720
Contributors: Nojoud Faqerah; Daniel Walker; Konstantinos Gerasimidis
Source: check_circle
Crossref

Outer membrane translocation of pyocins via the copper regulated TonB-dependent transporter CrtA

Biochemical Journal
2023-07-26 | Journal article
DOI: 10.1042/BCJ20220552
Contributors: Jiraphan Premsuriya; Khedidja Mosbahi; Iva Atanaskovic; Colin Kleanthous; Daniel Walker
Source: check_circle
Crossref
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Preferred source (of 2)‎

PF-431396 hydrate inhibition of kinase phosphorylation during adherent-invasive Escherichia coli infection inhibits intra-macrophage replication and inflammatory cytokine release

Microbiology
2023-06-13 | Journal article
DOI: 10.1099/mic.0.001337
Contributors: Xiang Li; Michael J. Ormsby; Ghaith Fallata; Lynsey M. Meikle; Daniel Walker; Damo Xu; Daniel M. Wall
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Targeted Delivery of Narrow-Spectrum Protein Antibiotics to the Lower Gastrointestinal Tract in a Murine Model of Escherichia coli Colonization

Frontiers in Microbiology
2021-10-14 | Journal article
DOI: 10.3389/fmicb.2021.670535
Part of ISSN: 1664-302X
Contributors: Nuria Carpena; Kerry Richards; Teresita D. J. Bello Gonzalez; Alberto Bravo-Blas; Nicholas G. Housden; Konstantinos Gerasimidis; Simon W. F. Milling; Gillian Douce; Danish J. Malik; Daniel Walker
Source: Self-asserted source
Daniel Walker

Challenges of using protein antibiotics for pathogen control

Pest Management Science
2021-09 | Journal article
DOI: 10.1002/ps.6312
Contributors: Ray Chai; William M Rooney; Joel J Milner; Daniel Walker
Source: check_circle
Crossref

Pyocin efficacy in a murine model of Pseudomonas aeruginosa sepsis

Journal of Antimicrobial Chemotherapy
2021-08-12 | Journal article
DOI: 10.1093/jac/dkab199
Contributors: Anne Six; Khedidja Mosbahi; Madhuri Barge; Colin Kleanthous; Thomas Evans; Daniel Walker
Source: check_circle
Crossref

FusB Energizes Import across the Outer Membrane through Direct Interaction with Its Ferredoxin Substrate

mBio
2020-10-27 | Journal article
DOI: 10.1128/mBio.02081-20
Contributors: Marta Wojnowska; Daniel Walker; M. Stephen Trent
Source: check_circle
Crossref

Engineering bacteriocin‐mediated resistance against the plant pathogen Pseudomonas syringae

Plant Biotechnology Journal
2020-05 | Journal article
DOI: 10.1111/pbi.13294
Contributors: William M. Rooney; Rhys W. Grinter; Annapaula Correia; Julian Parkhill; Daniel C. Walker; Joel J. Milner
Source: check_circle
Crossref

Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport

mBio
2020-04-28 | Journal article
DOI: 10.1128/mBio.03230-19
Contributors: Hannah M. Behrens; Edward D. Lowe; Joseph Gault; Nicholas G. Housden; Renata Kaminska; T. Moritz Weber; Catriona M. A. Thompson; Gaëtan L. A. Mislin; Isabelle J. Schalk; Daniel Walker et al.
Source: check_circle
Crossref

Pyocin efficacy in a murine model ofPseudomonas aeruginosasepsis

2020-03-29 | Preprint
DOI: 10.1101/2020.03.27.011908
Contributors: Anne Six; Khedidja Mosbahi; Madhuri Barge; Colin Kleanthous; Thomas Evans; Daniel Walker
Source: check_circle
Crossref

Bacterial iron acquisition mediated by outer membrane translocation and cleavage of a host protein

Proceedings of the National Academy of Sciences
2018-06-26 | Journal article
DOI: 10.1073/pnas.1800672115
Contributors: Khedidja Mosbahi; Marta Wojnowska; Amaya Albalat; Daniel Walker
Source: check_circle
Crossref

Exploitation of an iron transporter for bacterial protein antibiotic import

Proceedings of the National Academy of Sciences of the United States of America
2017 | Journal article
DOI: 10.1073/pnas.1713741114
EID:

2-s2.0-85033467440
Contributors: White, P.; Joshi, A.; Rassam, P.; Housden, N.G.; Kaminska, R.; Goult, J.D.; Redfield, C.; McCaughey, L.C.; Walker, D.; Mohammed, S. et al.
Source: Self-asserted source
Daniel Walker via Scopus - Elsevier

The Structure of a Conserved Domain of TamB Reveals a Hydrophobic β Taco Fold

Structure
2017 | Journal article
DOI: 10.1016/j.str.2017.10.002
EID:

2-s2.0-85033384223
Contributors: Josts, I.; Stubenrauch, C.J.; Vadlamani, G.; Mosbahi, K.; Walker, D.; Lithgow, T.; Grinter, R.
Source: Self-asserted source
Daniel Walker via Scopus - Elsevier

Efficacy of species-specific protein antibiotics in a murine model of acute Pseudomonas aeruginosa lung infection

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep30201
EID:

2-s2.0-84979243371
Contributors: McCaughey, L.C.; Ritchie, N.D.; Douce, G.R.; Evans, T.J.; Walker, D.
Source: Self-asserted source
Daniel Walker via Scopus - Elsevier

Structural and biophysical analysis of nuclease protein antibiotics

Biochemical Journal
2016 | Journal article
DOI: 10.1042/BCJ20160544
EID:

2-s2.0-85009502265
Contributors: Klein, A.; Wojdyla, J.A.; Joshi, A.; Josts, I.; McCaughey, L.C.; Housden, N.G.; Kaminska, R.; Byron, O.; Walker, D.; Kleanthous, C.
Source: Self-asserted source
Daniel Walker via Scopus - Elsevier

Structure of the bacterial plant-ferredoxin receptor FusA

Nature Communications
2016 | Journal article
DOI: 10.1038/ncomms13308
EID:

2-s2.0-84994045688
Contributors: Grinter, R.; Josts, I.; Mosbahi, K.; Roszak, A.W.; Cogdell, R.J.; Bonvin, A.M.J.J.; Milner, J.J.; Kelly, S.M.; Byron, O.; Smith, B.O. et al.
Source: Self-asserted source
Daniel Walker via Scopus - Elsevier

Discovery, characterisation and in vivo activity of pyocin SD2, a protein antibiotic from Pseudomonas aeruginosa.

2016-06 | Journal article
PMID: 27252387
Contributors: McCaughey LC; Josts I; Grinter R; White P; Byron O; Tucker NP; Matthews JM; Kleanthous C; Whitchurch CB; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central
grade
Preferred source (of 2)‎

The Potassium Binding Protein Kbp Is a Cytoplasmic Potassium Sensor.

2016-05 | Journal article
DOI: 10.1016/j.str.2016.03.017
PMID: 27112601
Contributors: Ashraf KU; Josts I; Mosbahi K; Kelly SM; Byron O; Smith BO; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

A Highly Conserved Bacterial D-Serine Uptake System Links Host Metabolism and Virulence.

2016-01 | Journal article
DOI: 10.1371/journal.ppat.1005359
PMID: 26727373
PMC: PMC4699771
Contributors: Connolly JP; Gabrielsen M; Goldstone RJ; Grinter R; Wang D; Cogdell RJ; Walker D; Smith DG; Roe AJ
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Activity of Species-specific Antibiotics Against Crohn's Disease-Associated Adherent-invasive Escherichia coli.

2015-10 | Journal article
DOI: 10.1097/MIB.0000000000000488
PMID: 26177305
Contributors: Brown CL; Smith K; Wall DM; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Structures of the Ultra-High-Affinity Protein-Protein Complexes of Pyocins S2 and AP41 and Their Cognate Immunity Proteins from Pseudomonas aeruginosa.

2015-08 | Journal article
DOI: 10.1016/j.jmb.2015.07.014
PMID: 26215615
PMC: PMC4548480
Contributors: Joshi A; Grinter R; Josts I; Chen S; Wojdyla JA; Lowe ED; Kaminska R; Sharp C; McCaughey L; Roszak AW et al.
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Structure of protease-cleaved Escherichia coli α-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment.

2015-07 | Journal article
DOI: 10.1107/S1399004715008548
PMID: 26143919
PMC: PMC4498604
Contributors: Fyfe CD; Grinter R; Josts I; Mosbahi K; Roszak AW; Cogdell RJ; Wall DM; Burchmore RJ; Byron O; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Consequences of inducing intrinsic disorder in a high-affinity protein-protein interaction.

2015-04 | Journal article
DOI: 10.1021/ja512607r
PMID: 25856265
Contributors: Papadakos G; Sharma A; Lancaster LE; Bowen R; Kaminska R; Leech AP; Walker D; Redfield C; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Recombinant expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal DUF490(963-1138) domain of TamB from Escherichia coli.

2014-09 | Journal article
DOI: 10.1107/S2053230X14017403
PMID: 25195908
Contributors: Josts I; Grinter R; Kelly SM; Mosbahi K; Roszak A; Cogdell R; Smith BO; Byron O; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Structure of the atypical bacteriocin pectocin M2 implies a novel mechanism of protein uptake.

2014-07 | Journal article
DOI: 10.1111/mmi.12655
PMID: 24865810
PMC: PMC4671253
Contributors: Grinter R; Josts I; Zeth K; Roszak AW; McCaughey LC; Cogdell RJ; Milner JJ; Kelly SM; Byron O; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Lectin-like bacteriocins from Pseudomonas spp. utilise D-rhamnose containing lipopolysaccharide as a cellular receptor.

2014-02 | Journal article
DOI: 10.1371/journal.ppat.1003898
PMID: 24516380
PMC: PMC3916391
Contributors: McCaughey LC; Grinter R; Josts I; Roszak AW; Waløen KI; Cogdell RJ; Milner J; Evans T; Kelly S; Tucker NP et al.
Source: Self-asserted source
Daniel Walker via Europe PubMed Central
grade
Preferred source (of 2)‎

Increased S-nitrosylation and proteasomal degradation of caspase-3 during infection contribute to the persistence of adherent invasive Escherichia coli (AIEC) in immune cells.

2013 | Journal article
DOI: 10.1371/journal.pone.0068386
PMID: 23861899
PMC: PMC3701656
Contributors: Dunne KA; Allam A; McIntosh A; Houston SA; Cerovic V; Goodyear CS; Roe AJ; Beatson SA; Milling SW; Walker D et al.
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Beware of proteins bearing gifts: protein antibiotics that use iron as a Trojan horse.

2013-01 | Journal article
DOI: 10.1111/1574-6968.12011
PMID: 22998625
Contributors: Grinter R; Milner J; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Ferredoxin containing bacteriocins suggest a novel mechanism of iron uptake in Pectobacterium spp.

2012 | Journal article
DOI: 10.1371/journal.pone.0033033
PMID: 22427936
PMC: PMC3302902
Contributors: Grinter R; Milner J; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Bacteriocins active against plant pathogenic bacteria.

2012-12 | Journal article
DOI: 10.1042/BST20120206
PMID: 23176505
Contributors: Grinter R; Milner J; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Colicin-like bacteriocins as novel therapeutic agents for the treatment of chronic biofilm-mediated infection.

2012-12 | Journal article
DOI: 10.1042/BST20120241
PMID: 23176515
Contributors: Brown CL; Smith K; McCaughey L; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

How bugs kill bugs: progress and challenges in bacteriocin research.

2012-12 | Journal article
DOI: 10.1042/BST20120253
PMID: 23176494
Contributors: Penfold CN; Walker D; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

The crystal structure of the lipid II-degrading bacteriocin syringacin M suggests unexpected evolutionary relationships between colicin M-like bacteriocins.

2012-11 | Journal article
DOI: 10.1074/jbc.M112.400150
PMID: 22995910
PMC: PMC3493929
Contributors: Grinter R; Roszak AW; Cogdell RJ; Milner JJ; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Discovery of an archetypal protein transport system in bacterial outer membranes.

2012-05 | Journal article
DOI: 10.1038/nsmb.2261
PMID: 22466966
Contributors: Selkrig J; Mosbahi K; Webb CT; Belousoff MJ; Perry AJ; Wells TJ; Morris F; Leyton DL; Totsika M; Phan MD et al.
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Activity of pyocin S2 against Pseudomonas aeruginosa biofilms.

2012-03 | Journal article
DOI: 10.1128/AAC.05714-11
PMID: 22183174
PMC: PMC3294903
Contributors: Smith K; Martin L; Rinaldi A; Rajendran R; Ramage G; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

The role of electrostatics in colicin nuclease domain translocation into bacterial cells.

2007-10 | Journal article
DOI: 10.1074/jbc.M705883200
PMID: 17720814
Contributors: Walker D; Mosbahi K; Vankemmelbeke M; James R; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Competitive recruitment of the periplasmic translocation portal TolB by a natively disordered domain of colicin E9.

2006-08 | Journal article
DOI: 10.1073/pnas.0603433103
PMID: 16894158
PMC: PMC1567883
Contributors: Loftus SR; Walker D; Maté MJ; Bonsor DA; James R; Moore GR; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Global structural rearrangement of the cell penetrating ribonuclease colicin E3 on interaction with phospholipid membranes.

2006-03 | Journal article
DOI: 10.1110/ps.051890306
PMID: 16452623
PMC: PMC2249781
Contributors: Mosbahi K; Walker D; James R; Moore GR; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Identification of the catalytic motif of the microbial ribosome inactivating cytotoxin colicin E3.

2004-06 | Journal article
DOI: 10.1110/ps.04658504
PMID: 15133158
PMC: PMC2279995
Contributors: Walker D; Lancaster L; James R; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Destabilization of the colicin E9 Endonuclease domain by interaction with negatively charged phospholipids: implications for colicin translocation into bacteria.

2004-05 | Journal article
DOI: 10.1074/jbc.M400402200
PMID: 15044477
Contributors: Mosbahi K; Walker D; Lea E; Moore GR; James R; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Transcriptional profiling of colicin-induced cell death of Escherichia coli MG1655 identifies potential mechanisms by which bacteriocins promote bacterial diversity.

2004-02 | Journal article
DOI: 10.1128/JB.186.3.866-869.2004
PMID: 14729715
PMC: PMC321497
Contributors: Walker D; Rolfe M; Thompson A; Moore GR; James R; Hinton JC; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

OmpF enhances the ability of BtuB to protect susceptible Escherichia coli cells from colicin E9 cytotoxicity.

2003-06 | Journal article
DOI: 10.1016/S0014-5793(03)00511-8
PMID: 12804762
Contributors: Law CJ; Penfold CN; Walker DC; Moore GR; James R; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Thermodynamic consequences of bipartite immunity protein binding to the ribosomal ribonuclease colicin E3.

2003-04 | Journal article
DOI: 10.1021/bi0273720
PMID: 12680770
Contributors: Walker D; Moore GR; James R; Kleanthous C
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

PrrC from Rhodobacter sphaeroides, a homologue of eukaryotic Sco proteins, is a copper-binding protein and may have a thiol-disulfide oxidoreductase activity

FEBS Letters
2002 | Journal article
DOI: 10.1016/S0014-5793(02)02532-2
EID:

2-s2.0-0037042213
Contributors: McEwan, A.G.; Lewin, A.; Davy, S.L.; Boetzel, R.; Leech, A.; Walker, D.; Wood, T.; Moore, G.R.
Source: Self-asserted source
Daniel Walker via Scopus - Elsevier

Mutagenic scan of the H-N-H motif of colicin E9: implications for the mechanistic enzymology of colicins, homing enzymes and apoptotic endonucleases.

2002-07 | Journal article
DOI: 10.1093/nar/gkf420
PMID: 12136104
PMC: PMC135741
Contributors: Walker DC; Georgiou T; Pommer AJ; Walker D; Moore GR; Kleanthous C; James R
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9.

2001-12 | Journal article
DOI: 10.1006/jmbi.2001.5189
PMID: 11733993
Contributors: Pommer AJ; Cal S; Keeble AH; Walker D; Evans SJ; Kühlmann UC; Cooper A; Connolly BA; Hemmings AM; Moore GR et al.
Source: Self-asserted source
Daniel Walker via Europe PubMed Central

Immunity proteins: enzyme inhibitors that avoid the active site.

2001-10 | Journal article
DOI: 10.1016/S0968-0004(01)01941-7
PMID: 11590016
Contributors: Kleanthous C; Walker D
Source: Self-asserted source
Daniel Walker via Europe PubMed Central
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