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School of Life Sciences
CLS

Keywords

Tumour Metabolism, metabolite sensing, immunometabolism

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China

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Employment (1)

Tsinghua University: Beijing, Beijing, CN

2014-10-24 to present | Associate Professor (School of Life Sciences)
Employment
Source: Self-asserted source
Peng Jiang

Education and qualifications (1)

Tsinghua University: Beijing, Beijing, CN

Qualification
Source: Self-asserted source
Peng Jiang

Professional activities (1)

Center for Life Sciences: Beijing, CN

Invited position
Source: Self-asserted source
Peng Jiang

Works (34)

Metabolic determinants of germinal center B cell formation and responses

Nature Chemical Biology
2025-03 | Journal article
DOI: 10.1038/s41589-024-01690-6
Contributors: Jun Wu; Jiawen Zhou; Gen Li; Xuan Sun; Chen Xiang; Haiyan Chen; Peng Jiang
Source: check_circle
Crossref

ETV7 limits the antiviral and antitumor efficacy of CD8<sup>+</sup> T cells by diverting their fate toward exhaustion.

Nature cancer
2025-01-13 | Journal article | Author
DOI: 10.1038/s43018-024-00892-0
PMID: 39805956
Contributors: Cheng J; Xiao Y; Peng T; Zhang Z; Qin Y; Wang Y; Shi J; Yan J; Zhao Z; Liangtao Zheng et al.
Source: Self-asserted source
Peng Jiang

Metabolic reprogramming, sensing, and cancer therapy

Cell Reports
2024-12 | Journal article
DOI: 10.1016/j.celrep.2024.115064
Contributors: Youxiang Mao; Ziyan Xia; Wenjun Xia; Peng Jiang
Source: check_circle
Crossref

Hydrolyzing NAD to NMN and AMP by SelO is Required for Mitochondria Homeostasis

2024-10-18 | Preprint
DOI: 10.21203/rs.3.rs-5137152/v1
Contributors: Ting Wang; Xiaofan Jia; Teng Zhang; Chenxi Yang; Li Wu; Longfei Diao; Yuting Yang; Jie Wu; Yeyi Li; Peng Jiang et al.
Source: check_circle
Crossref

Metabolism-inflammasome crosstalk shapes innate and adaptive immunity

Cell Chemical Biology
2024-05 | Journal article
DOI: 10.1016/j.chembiol.2024.04.006
Contributors: Jun Wu; Xuan Sun; Peng Jiang
Source: check_circle
Crossref

Tumor–Host Cometabolism Collaborates to Shape Cancer Immunity

Cancer Discovery
2024-04-04 | Journal article
DOI: 10.1158/2159-8290.CD-23-1509
Contributors: Yingcheng Wu; Qiang Zou; Peng Jiang; Qiang Gao
Source: check_circle
Crossref

A glycolytic metabolite that drives BRCA2 haploinsufficiency.

Cell
2024-04-01 | Journal article
DOI: 10.1016/j.cell.2024.03.028
PMID: 38670069
Contributors: Jiang P
Source: Self-asserted source
Peng Jiang

p53 promotes antiviral innate immunity by driving hexosamine metabolism

Cell Reports
2024-02 | Journal article
DOI: 10.1016/j.celrep.2024.113724
Contributors: Wenjun Xia; Peng Jiang
Source: check_circle
Crossref

p53 suppresses lipid droplet–fueled tumorigenesis through phosphatidylcholine

Journal of Clinical Investigation
2024-02-15 | Journal article
DOI: 10.1172/JCI171788
Contributors: Xiuduan Xu; Jianqin Wang; Li Xu; Peng Li; Peng Jiang
Source: check_circle
Crossref

AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis

Nature Communications
2024-01-23 | Journal article
DOI: 10.1038/s41467-024-44772-8
Contributors: Taiqi Chen; Siyi Xie; Jie Cheng; Qiao Zhao; Hong Wu; Peng Jiang; Wenjing Du
Source: check_circle
Crossref

The crisscross between p53 and metabolism in cancer.

Acta biochimica et biophysica Sinica
2023-06-01 | Journal article
DOI: 10.3724/abbs.2023109
PMID: 37337630
PMC: PMC10326413
Contributors: Mao Y; Jiang P
Source: Self-asserted source
Peng Jiang

Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8<sup>+</sup> T cells in the tumor microenvironment.

Cell metabolism
2023-05-12 | Journal article
DOI: 10.1016/j.cmet.2023.04.017
PMID: 37178684
Contributors: Cheng J; Yan J; Ying Liu; Shi J; Wang H; Zhou H; Zhou Y; Zhang T; Zhao L; Meng X et al.
Source: Self-asserted source
Peng Jiang

p53 protects against alcoholic fatty liver disease via ALDH2 inhibition

The EMBO Journal
2023-04-17 | Journal article
DOI: 10.15252/embj.2022112304
Contributors: Pengbo Yao; Zhenxi Zhang; Hongchao Liu; Peng Jiang; Wei Li; Wenjing Du
Source: check_circle
Crossref

Ultrasensitive HPLC-MS Quantification of <i>S</i>-(2-Succino) Cysteine Based on Ethanol/Acetyl Chloride Derivatization in Fumarate Accumulation Cells.

Analytical chemistry
2023-01-10 | Journal article
DOI: 10.1021/acs.analchem.2c03573
PMID: 36625376
Contributors: Ying Liu; Chen YN; Cheng J; Yan JX; Xue CY; Pan HY; Shen XY; Jiang Zhou; Jiang P; Ying-Lin Zhou et al.
Source: Self-asserted source
Peng Jiang

Fumarate suppresses B-cell activation and function through direct inactivation of LYN.

Nature chemical biology
2022-06-16 | Journal article
DOI: 10.1038/s41589-022-01052-0
PMID: 35710616
Source: Self-asserted source
Peng Jiang

Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate

Nature Metabolism
2022-02-28 | Journal article
DOI: 10.1038/s42255-022-00532-w
Contributors: Mengjia Zhao; Pengbo Yao; Youxiang Mao; Jinjun Wu; Weihua Wang; Chenhui Geng; Jie Cheng; Wenjing Du; Peng Jiang
Source: check_circle
Crossref

Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses.

Molecular cell
2022-01-10 | Journal article
DOI: 10.1016/j.molcel.2021.12.006
PMID: 35016033
Source: Self-asserted source
Peng Jiang

Detection of CD8<sup>+</sup> T cell-mediated immune responses to bacterial infection in mice.

STAR protocols
2021-12-13 | Journal article
DOI: 10.1016/j.xpro.2021.101022
PMID: 34977671
PMC: PMC8683771
Source: Self-asserted source
Peng Jiang

Cancer metabolism and tumor microenvironment: fostering each other?

Science China. Life sciences
2021-11-26 | Journal article
DOI: 10.1007/s11427-021-1999-2
PMID: 34846643
Source: Self-asserted source
Peng Jiang

A Different Facet of p53 Function: Regulation of Immunity and Inflammation During Tumor Development.

Frontiers in cell and developmental biology
2021-10-18 | Journal article
DOI: 10.3389/fcell.2021.762651
PMID: 34733856
PMC: PMC8558413
Source: Self-asserted source
Peng Jiang

p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage.

Proceedings of the National Academy of Sciences of the United States of America
2021-07-01 | Journal article
DOI: 10.1073/pnas.2019822118
PMID: 34244426
PMC: PMC8285905
Source: Self-asserted source
Peng Jiang

CREB1 and ATF1 Negatively Regulate Glutathione Biosynthesis Sensitizing Cells to Oxidative Stress.

Frontiers in cell and developmental biology
2021-06-10 | Journal article
DOI: 10.3389/fcell.2021.698264
PMID: 34179023
PMC: PMC8223876
Contributors: Zhao L; Xia W; Jiang P
Source: Self-asserted source
Peng Jiang

Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance.

Cell metabolism
2021-04-21 | Journal article
DOI: 10.1016/j.cmet.2021.04.001
PMID: 33910046
Source: Self-asserted source
Peng Jiang

Asparagine enhances LCK signalling to potentiate CD8+ T-cell activation and anti-tumour responses

Nature Cell Biology
2021-01 | Journal article
DOI: 10.1038/s41556-020-00615-4
Contributors: Jun Wu; Gen Li; Le Li; Dan Li; Zhongjun Dong; Peng Jiang
Source: check_circle
Crossref

p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival.

Nature communications
2020-04-09 | Journal article
DOI: 10.1038/s41467-020-15573-6
PMID: 32273511
PMC: PMC7145870
Source: Self-asserted source
Peng Jiang

Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T-cell Leukemogenesis.

Cancer cell
2020-02-01 | Journal article
DOI: 10.1016/j.ccell.2020.01.001
PMID: 32049046
PMC: PMC7321798
Source: Self-asserted source
Peng Jiang

Publisher Correction: p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis.

Nature
2019-05-01 | Journal article
DOI: 10.1038/s41586-019-1121-7
PMID: 31086338
Source: Self-asserted source
Peng Jiang

p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis.

Nature
2019-03-06 | Journal article
DOI: 10.1038/s41586-019-0996-7
PMID: 30842655
Source: Self-asserted source
Peng Jiang

TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation.

Nature communications
2018-11-08 | Journal article
DOI: 10.1038/s41467-018-07127-8
PMID: 30409970
PMC: PMC6224601
Source: Self-asserted source
Peng Jiang

Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.

The Journal of biological chemistry
2017-08-28 | Journal article
DOI: 10.1074/jbc.m117.810309
PMID: 28848047
PMC: PMC5641861
Source: Self-asserted source
Peng Jiang

Regulation of the pentose phosphate pathway in cancer.

Protein & cell
2014-07-12 | Journal article
DOI: 10.1007/s13238-014-0082-8
PMID: 25015087
PMC: PMC4112277
Source: Self-asserted source
Peng Jiang
grade
Preferred source (of 2)‎

TAp73 enhances the pentose phosphate pathway and supports cell proliferation.

Nature cell biology
2013-06-30 | Journal article
DOI: 10.1038/ncb2789
PMID: 23811687
PMC: PMC3733810
Source: Self-asserted source
Peng Jiang

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence.

Nature
2013-01-13 | Journal article
DOI: 10.1038/nature11776
PMID: 23334421
PMC: PMC3561500
Source: Self-asserted source
Peng Jiang

p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase.

Nature cell biology
2011-02-20 | Journal article
DOI: 10.1038/ncb2172
PMID: 21336310
PMC: PMC3110666
Source: Self-asserted source
Peng Jiang
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