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Employment (1)

Chongqing University: Chongqing, CN

2020-05-01 to present | Professor (Bioengineering)
Employment
Source: Self-asserted source
Mingxing Lei

Education and qualifications (2)

University of Southern California: Los Angeles, CA, US

2014-12-25 to 2017-02-01 | Postdoctoral Fellow (Department of Pathology)
Education
Source: Self-asserted source
Mingxing Lei

Chongqing University: Chongqing, Sichuan, CN

2010-09-01 to 2014-12-25 | Ph.D. (College of Biomedical Engineering)
Education
Source: Self-asserted source
Mingxing Lei

Works (47)

Metabolic adaptation drives self-organization during skin organoid morphogenesis

2024-08-23 | Preprint
DOI: 10.21203/rs.3.rs-4773919/v1
Contributors: Mingxing Lei; Jingwei Jiang; Weiwei Liu; Mengyue Wang; Dehuan Wang; Wang Wu; Man Zhang; Siyi Zhou; Yang Xiao; Xiao Xiang et al.
Source: check_circle
Crossref

Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures

npj Regenerative Medicine
2023-11-23 | Journal article
DOI: 10.1038/s41536-023-00340-0
Contributors: Mingxing Lei; Jingwei Jiang; Mengyue Wang; Wang Wu; Jinwei Zhang; Wanqian Liu; Wei Zhou; Yung-Chih Lai; Ting-Xin Jiang; Randall B. Widelitz et al.
Source: check_circle
Crossref

The mechano-chemical circuit drives skin organoid self-organization

Proceedings of the National Academy of Sciences
2023-09-05 | Journal article
DOI: 10.1073/pnas.2221982120
Contributors: Mingxing Lei; Hans I-Chen Harn; Qiwei Li; Jingwei Jiang; Wang Wu; Wei Zhou; Tin-Xin Jiang; Mengyue Wang; Jinwei Zhang; Yung-Chih Lai et al.
Source: check_circle
Crossref

Editorial: Inflammation, stem cells and wound healing in skin aging.

Frontiers in cell and developmental biology
2022-10 | Journal article
DOI: 10.3389/fcell.2022.1046022
PMID: 36313548
Contributors: Lei M; Lien WH; Li J
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Biomechanical Regulatory Factors and Therapeutic Targets in Keloid Fibrosis.

Frontiers in pharmacology
2022-05 | Journal article
DOI: 10.3389/fphar.2022.906212
PMID: 35614943
PMC: PMC9124765
Contributors: Feng F; Liu M; Pan L; Wu J; Wang C; Yang L; Liu W; Xu W; Lei M
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Stability and Biosafety of human epidermal stem cell for wound repair: Preclinical evaluation

2022-05 | Preprint
DOI: 10.21203/rs.3.rs-1683817/v1
PPR: PPR498980
Contributors: Zhao X; Li X; Wang Y; Guo Y; Huang Y; Lv D; Lei M; Yu S; Luo G; zhan r
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Environmental Regulation of Skin Pigmentation and Hair Regeneration.

Stem cells and development
2022-03 | Journal article
DOI: 10.1089/scd.2022.29011.wwu
PMID: 35285756
Contributors: Wu W; Yang J; Tao H; Lei M
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

The global regulatory logic of organ regeneration: circuitry lessons from skin and its appendages

Biological Reviews
2021-12 | Journal article
DOI: 10.1111/brv.12767
Contributors: ZhiCao Yue; Mingxing Lei; Ralf Paus; Cheng‐Ming Chuong
Source: check_circle
Crossref

Editorial: Hair Follicle Stem Cell Regeneration in Aging.

Frontiers in cell and developmental biology
2021-11 | Journal article
DOI: 10.3389/fcell.2021.799268
PMID: 34901037
PMC: PMC8655873
Contributors: Lei M; Lin SJ; Chuong CM
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Hey1 promotes migration and invasion of melanoma cells via GRB2/PI3K/AKT signaling cascade.

Journal of Cancer
2021-10 | Journal article
DOI: 10.7150/jca.60974
PMID: 34729100
PMC: PMC8558658
Contributors: Pu Y; Lei M; Chen Y; Huang Y; Zhang L; Chen J; Zhang Y; Shao X; Liu L; Chen J
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Cyclic growth of dermal papilla and regeneration of follicular mesenchymal components during feather cycling

Development
2021-09-15 | Journal article
DOI: 10.1242/dev.198671
Contributors: Ping Wu; Ting-Xin Jiang; Mingxing Lei; Chih-Kuan Chen; Shu-Man Hsieh Li; Randall B. Widelitz; Cheng-Ming Chuong
Source: check_circle
Crossref

Bach2 regulates autophagy to modulate UVA-induced photoaging in skin fibroblasts.

Free radical biology & medicine
2021-04 | Journal article
DOI: 10.1016/j.freeradbiomed.2021.04.003
PMID: 33882335
Contributors: Wang M; Lei M; Chang L; Xing Y; Guo Y; Pourzand C; Bartsch JW; Chen J; Luo J; WidyaKarisma V et al.
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging.

Frontiers in cell and developmental biology
2021-02 | Journal article
DOI: 10.3389/fcell.2021.635340
PMID: 33681217
PMC: PMC7933214
Contributors: Harn HI; Chen CC; Wang SP; Lei M; Chuong CM
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

UVA-Triggered Drug Release and Photo-Protection of Skin.

Frontiers in cell and developmental biology
2021-02 | Journal article
DOI: 10.3389/fcell.2021.598717
PMID: 33644041
PMC: PMC7905215
Contributors: Karisma VW; Wu W; Lei M; Liu H; Nisar MF; Lloyd MD; Pourzand C; Zhong JL
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells.

Frontiers in cell and developmental biology
2020-11 | Journal article
DOI: 10.3389/fcell.2020.583434
PMID: 33324639
PMC: PMC7726222
Contributors: Weber EL; Lai YC; Lei M; Jiang TX; Chuong CM
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Skin Cyst: A Pathological Dead-End With a New Twist of Morphogenetic Potentials in Organoid Cultures.

Frontiers in cell and developmental biology
2020-01 | Journal article
DOI: 10.3389/fcell.2020.628114
PMID: 33511139
PMC: PMC7835531
Contributors: Qiu W; Gu PR; Chuong CM; Lei M
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

The Making of a Flight Feather: Bio-architectural Principles and Adaptation.

Cell
2019-11 | Journal article
DOI: 10.1016/j.cell.2019.11.008
PMID: 31778655
Contributors: Chang WL; Wu H; Chiu YK; Wang S; Jiang TX; Luo ZL; Lin YC; Li A; Hsu JT; Huang HL et al.
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

NFAT5 mediates hypertonic stress-induced atherosclerosis via activating NLRP3 inflammasome in endothelium.

Cell communication and signaling : CCS
2019-08 | Journal article
DOI: 10.1186/s12964-019-0406-7
PMID: 31429763
PMC: PMC6701070
Contributors: Ma P; Zha S; Shen X; Zhao Y; Li L; Yang L; Lei M; Liu W
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Comparative regenerative biology of spiny (Acomys cahirinus) and laboratory (Mus musculus) mouse skin.

Experimental dermatology
2019-02 | Journal article
DOI: 10.1111/exd.13899
PMID: 30734959
Contributors: Jiang TX; Harn HI; Ou KL; Lei M; Chuong CM
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central
grade
Preferred source (of 2)‎

Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials.

Experimental dermatology
2018-12 | Journal article
DOI: 10.1111/exd.13856
PMID: 30537004
Contributors: Qiu W; Chuong CM; Lei M
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central
grade
Preferred source (of 2)‎

Epidermal Darwinism and Competitive Equilibrium within the Epidermis.

Cell stem cell
2018-11 | Journal article
DOI: 10.1016/j.stem.2018.10.019
PMID: 30388416
Contributors: Lei M; Chuong CM
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Suppression of IGF1R in Melanoma Cells by an Adenovirus-Mediated One-Step Knockdown System.

Molecular therapy. Nucleic acids
2018-08 | Journal article
DOI: 10.1016/j.omtn.2018.08.004
PMID: 30161025
PMC: PMC6120749
Contributors: Xin H; Lei M; Zhang Z; Li J; Zhang H; Luo X; Wang A; Deng F
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro.

Methods in molecular biology (Clifton, N.J.)
2018-04 | Journal article
DOI: 10.1007/7651_2018_143
PMID: 29704117
Contributors: Yang K; Qiu W; Gu PR; Lei M
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Cyclic mechanical stretch enhances BMP9-induced osteogenic differentiation of mesenchymal stem cells.

International orthopaedics
2018-02 | Journal article
DOI: 10.1007/s00264-018-3796-z
PMID: 29429074
Contributors: Song Y; Tang Y; Song J; Lei M; Liang P; Fu T; Su X; Zhou P; Yang L; Huang E
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Getting to the Core of the Dermal Papilla.

The Journal of investigative dermatology
2017-11 | Journal article
DOI: 10.1016/j.jid.2017.07.824
PMID: 29055410
Contributors: Lei M; Yang L; Chuong CM
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway.

Oncotarget
2017-10 | Journal article
DOI: 10.18632/oncotarget.22212
PMID: 29245976
PMC: PMC5725018
Contributors: He L; Lei M; Xing Y; Li Y; Hu C; Chen P; Lian X; Yang T; Liu W; Yang L
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Wnt/β-catenin signaling promotes aging-associated hair graying in mice.

Oncotarget
2017-09 | Journal article
DOI: 10.18632/oncotarget.20613
PMID: 29050206
PMC: PMC5642481
Contributors: Zhang Z; Lei M; Xin H; Hu C; Yang T; Xing Y; Li Y; Guo H; Lian X; Deng F
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells.

Proceedings of the National Academy of Sciences of the United States of America
2017-08 | Journal article
DOI: 10.1073/pnas.1700475114
PMID: 28798065
PMC: PMC5576784
Contributors: Lei M; Schumacher LJ; Lai YC; Juan WT; Yeh CY; Wu P; Jiang TX; Baker RE; Widelitz RB; Yang L et al.
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Hair follicle stem cell proliferation, Akt and Wnt signaling activation in TPA-induced hair regeneration.

Histochemistry and cell biology
2017-02 | Journal article
DOI: 10.1007/s00418-017-1540-1
PMID: 28185006
Contributors: Qiu W; Lei M; Zhou L; Bai X; Lai X; Yu Y; Yang T; Lian X
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle.

Stem cells international
2017-02 | Journal article
DOI: 10.1155/2017/2857478
PMID: 28337220
PMC: PMC5350338
Contributors: Guo H; Lei M; Li Y; Liu Y; Tang Y; Xing Y; Deng F; Yang K
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

12-O-tetradecanoylphorbol-13-acetate activates hair follicle melanocytes for hair pigmentation via Wnt/β-catenin signaling.

Cell and tissue research
2016-07 | Journal article
DOI: 10.1007/s00441-016-2450-6
PMID: 27464529
Contributors: Qiu W; Tang H; Guo H; Lei M; Yan H; Lian X; Wu J
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

STEM CELLS. Aging, alopecia, and stem cells.

Science (New York, N.Y.)
2016-02 | Journal article
DOI: 10.1126/science.aaf1635
PMID: 26912687
Contributors: Lei M; Chuong CM
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Hoxc13 is a crucial regulator of murine hair cycle.

Cell and tissue research
2015-11 | Journal article
DOI: 10.1007/s00441-015-2312-7
PMID: 26553656
Contributors: Qiu W; Lei M; Tang H; Yan H; Wen X; Zhang W; Tan R; Wang D; Wu J
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Mechano-growth factor enhances differentiation of bone marrow-derived mesenchymal stem cells

Biotechnology letters
2015-11 | Journal article
OTHER-ID:

IND604393635
Contributors: Li H; Lei M; Luo Z; Wu S; Zhong L; Xu Z; Lv Y; Yang L
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Mechano growth factor-E regulates apoptosis and inflammatory responses in fibroblast-like synoviocytes of knee osteoarthritis.

International orthopaedics
2015-09 | Journal article
DOI: 10.1007/s00264-015-2974-5
PMID: 26338342
Contributors: Li H; Lei M; Yu C; Lv Y; Song Y; Yang L
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Mechano-growth factor enhances differentiation of bone marrow-derived mesenchymal stem cells.

Biotechnology letters
2015-09 | Journal article
DOI: 10.1007/s10529-015-1915-0
PMID: 26330369
Contributors: Li H; Lei M; Luo Z; Wu S; Zhong L; Xu Z; Lv Y; Yang L
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Prolonged overexpression of Wnt10b induces epidermal keratinocyte transformation through activating EGF pathway.

Histochemistry and cell biology
2015-05 | Journal article
DOI: 10.1007/s00418-015-1330-6
PMID: 25995040
PMC: PMC5572676
Contributors: Lei M; Lai X; Bai X; Qiu W; Yang T; Liao X; Chuong CM; Yang L; Lian X; Zhong JL
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Roles of GasderminA3 in Catagen-Telogen Transition During Hair Cycling.

The Journal of investigative dermatology
2015-04 | Journal article
DOI: 10.1038/jid.2015.147
PMID: 25860385
PMC: PMC4537385
Contributors: Bai X; Lei M; Shi J; Yu Y; Qiu W; Lai X; Liu Y; Yang T; Yang L; Widelitz RB et al.
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

SCF/c-kit signaling is required in 12-O-tetradecanoylphorbol-13-acetate-induced migration and differentiation of hair follicle melanocytes for epidermal pigmentation.

Cell and tissue research
2015-03 | Journal article
DOI: 10.1007/s00441-014-2101-8
PMID: 25727244
Contributors: Qiu W; Yang K; Lei M; Yan H; Tang H; Bai X; Yang G; Lian X; Wu J
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Activated hair follicle stem cells and Wnt/β-catenin signaling involve in pathnogenesis of sebaceous neoplasms.

International journal of medical sciences
2014-07 | Journal article
DOI: 10.7150/ijms.8383
PMID: 25076848
PMC: PMC4115241
Contributors: Qiu W; Lei M; Li J; Wang N; Lian X
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Modulating hair follicle size with Wnt10b/DKK1 during hair regeneration.

Experimental dermatology
2014-06 | Journal article
DOI: 10.1111/exd.12416
PMID: 24750467
PMC: PMC4383245
Contributors: Lei M; Guo H; Qiu W; Lai X; Yang T; Widelitz RB; Chuong CM; Lian X; Yang L
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Therapeutic strategy for hair regeneration: hair cycle activation, niche environment modulation, wound-induced follicle neogenesis, and stem cell engineering.

Expert opinion on biological therapy
2013-01 | Journal article
DOI: 10.1517/14712598.2013.739601
PMID: 23289545
PMC: PMC3706200
Contributors: Chueh SC; Lin SJ; Chen CC; Lei M; Wang LM; Widelitz R; Hughes MW; Jiang TX; Chuong CM
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Tuning Wnt signals for more or fewer hairs.

The Journal of investigative dermatology
2013-01 | Journal article
DOI: 10.1038/jid.2012.446
PMID: 23299447
PMC: PMC3686512
Contributors: Lei MX; Chuong CM; Widelitz RB
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Upregulation of interfollicular epidermal and hair infundibulum β-catenin expression in Gsdma3 mutant mice.

Acta histochemica
2012-06 | Journal article
DOI: 10.1016/j.acthis.2012.04.002
PMID: 22694914
Contributors: Lei M; Yang T; Lai X; Bai X; Qiu W; Lian X; Yang L
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Gsdma3 is a new factor needed for TNF-α-mediated apoptosis signal pathway in mouse skin keratinocytes.

Histochemistry and cell biology
2012-05 | Journal article
DOI: 10.1007/s00418-012-0960-1
PMID: 22585037
Contributors: Lei M; Bai X; Yang T; Lai X; Qiu W; Yang L; Lian X
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Gsdma3 gene is needed for the induction of apoptosis-driven catagen during mouse hair follicle cycle.

Histochemistry and cell biology
2011-07 | Journal article
DOI: 10.1007/s00418-011-0845-8
PMID: 21805153
Contributors: Lei M; Gao X; Yang L; Yang T; Lian X
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

The expression and role of c-Myc in mouse hair follicle morphogenesis and cycling.

Acta histochemica
2011-05 | Journal article
DOI: 10.1016/j.acthis.2011.04.009
PMID: 21621827
Contributors: Wang N; Yang T; Li J; Lei M; Shi J; Qiu W; Lian X
Source: Self-asserted source
Mingxing Lei via Europe PubMed Central

Peer review (34 reviews for 18 publications/grants)

Review activity for Advanced materials interfaces. (1)
Review activity for Biochemical and biophysical research communications. (2)
Review activity for Biochemical pharmacology. (2)
Review activity for Biochemistry and biophysics reports. (1)
Review activity for Cell regeneration. (1)
Review activity for Cell reports. (2)
Review activity for Cell stem cell. (3)
Review activity for Cellular and molecular life sciences (1)
Review activity for Communications biology. (5)
Review activity for Current opinion in genetics & development. (1)
Review activity for Free radical biology & medicine. (2)
Review activity for Genes & diseases. (2)
Review activity for Heliyon. (5)
Review activity for Jo'jig gonghag gwa jaesaeng uihag (1)
Review activity for Journal of Advanced Research (2)
Review activity for Nature communications (1)
Review activity for Nature protocols (1)
Review activity for The Innovation. (1)
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