Personal information

Clinical pharmacology, Drug safety, Medication safety, Patient safety, Pharmacogenomics, Pharmacogenetics, Pharmacovigilance, Pharmacoepidemiology, Clinical toxicology, Toxicoepidemiology
Switzerland

Biography

Professor Alessandro Ceschi, M.D., M.Sc., EuCP, FEAPCCT, FRCP Edin, is a clinical pharmacologist and toxicologist and general internal medicine specialist physician (board certified). He is Chief physician and Medical and scientific director of the Institute of Pharmacological Sciences of Southern Switzerland, the Head of the Division of clinical pharmacology and toxicology, which includes the Regional pharmacovigilance centre, and the Chairman of the Drug and Therapeutics Committee at Ente Ospedaliero Cantonale (EOC). He is Director of the Clinical Trial Unit EOC (CTU-EOC) and Deputy Chief of the Academic Education, Research and Innovation Area of the General Directorate EOC. He has been the Coordinator of the Accompanying group EOC-Faculty of Biomedical Sciences USI and Member of the EOC Scientific Research Advisory Board.
Prof. Ceschi is Consultant at the Department of clinical pharmacology and toxicology of the University Hospital Zurich.
He is Professor of medicine (Titularprofessor) in clinical pharmacology and toxicology at the Faculty of Biomedical Sciences of the University of Southern Switzerland, Senior lecturer in clinical pharmacology and toxicology at the Faculty of medicine of the University of Zurich, and Lecturer in clinical toxicology at the Department of pharmaceutical sciences of the University of Basel.
He is Member elected by the Federal Council as representative of the Swiss Medical Association at the Federal Drug Commission of the Swiss Federal Office of Public Health.
Prof. Ceschi is Board member at the Swiss Society of Clinical Pharmacology and Toxicology, Steering Committee member at the Swiss Group of Pharmacogenomics and Personalised Therapy, and is active Member of several international and national scientific medical societies. He is Fellow of the European Association of Poisons Centres and Clinical Toxicologists.
He is Expert for the World Health Organization Global Patient Safety Challenge Medication Without Harm, Member of the WHO Global Patient Safety Network, and Collaborator at the Center for the Advancement of Healthcare Quality and Patient Safety.

Activities

Employment (3)

University of Southern Switzerland: Lugano, CH

2019 to present | Professor (Faculty of Biomedical Sciences)
Employment
Source: Self-asserted source
Alessandro Ceschi

Ente Ospedaliero Cantonale: Lugano, CH

2015 to present | Medical and Scientific Director (Institute of Pharmacological Sciences of Southern Switzerland)
Employment
Source: Self-asserted source
Alessandro Ceschi

University Hospital of Zurich: Zurich, CH

2013 to present | Consultant (Department of Clinical Pharmacology and Toxicology)
Employment
Source: Self-asserted source
Alessandro Ceschi

Education and qualifications (6)

University of Zurich: Zurich, CH

M.D.
Education
Source: Self-asserted source
Alessandro Ceschi

University of Zurich: Zurich, CH

PD Dr. med.
Qualification
Source: Self-asserted source
Alessandro Ceschi

Université de Bordeaux: Talence, Aquitaine, FR

M.Sc.
Qualification
Source: Self-asserted source
Alessandro Ceschi

Università della Svizzera Italiana: Lugano, TI, CH

Professor
Qualification
Source: Self-asserted source
Alessandro Ceschi

Swiss medical association: Bern, CH

Board Certification - Clinical Pharmacology and Toxicology
Qualification
Source: Self-asserted source
Alessandro Ceschi

Swiss medical association: Bern, CH

Board Certification - General Internal Medicine
Qualification
Source: Self-asserted source
Alessandro Ceschi

Works (50 of 96)

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Page 1 of 2

Antipsychotic, benzodiazepine and Z-drug prescriptions in a Swiss hospital network in the Choosing Wisely and COVID-19 eras: a longitudinal study

Swiss Medical Weekly
2024-11-01 | Journal article
Contributors: Vanessa Gagliano; Gloria Salemme; Alessandro Ceschi; Angela Greco; Nicola Grignoli; Luca Clivio; Alessandro Merler; Vanessa Feyling Benitez; Jvan Gianini; Martina Zandonà et al.
Source: check_circle
Crossref

Safety of Monoclonal Antibodies Inhibiting PCSK9 in Pregnancy: Disproportionality Analysis in VigiBase®

Clinical Pharmacology & Therapeutics
2024-08 | Journal article
Contributors: Roberta Noseda; Francesca Bedussi; Alice Panchaud; Alessandro Ceschi
Source: check_circle
Crossref

Calcitonin gene-related peptide antagonists in pregnancy: a disproportionality analysis in VigiBase®

The Journal of Headache and Pain
2024-01-19 | Journal article
Contributors: Roberta Noseda; Francesca Bedussi; Claudio Gobbi; Alessandro Ceschi; Chiara Zecca
Source: check_circle
Crossref

Determinants of Admission to Critical Care Following Acute Recreational Drug Toxicity: A Euro-DEN Plus Study

Journal of Clinical Medicine
2023-09 | Journal article | Author
Contributors: Roberta Noseda; MATTEO FRANCHI; Alberto Pagnamenta; Laura Müller; Alison M. Dines; Isabelle Giraudon; Fridtjof Heyerdahl; Florian Eyer; Knut Erik Hovda; Matthias E. Liechti et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Four cases of audio-vestibular disorders related to immunisation with SARS-CoV-2 mRNA vaccines

International Journal of Audiology
2023-06-01 | Journal article
Contributors: Pierre Ekobena; Laura E. Rothuizen; Francesca Bedussi; Pierre Guilcher; Sylvain Meylan; Alessandro Ceschi; François Girardin; Kim Dao
Source: check_circle
Crossref

Safety profile of monoclonal antibodies targeting the calcitonin gene-related peptide system in pregnancy: Updated analysis in VigiBase®

Cephalalgia
2023-04 | Journal article
Contributors: Roberta Noseda; Francesca Bedussi; Claudio Gobbi; Alessandro Ceschi; Chiara Zecca
Source: check_circle
Crossref

Spikevax booster and delayed urticaria: a Swiss signal with diagnostic uncertainties due to a high proportion of direct patient reports

European Journal of Clinical Pharmacology
2022-12 | Journal article
Contributors: Roberta Noseda; Laura Müller; Thomas Stammschulte; Raffaela Bertoli; Alessandro Ceschi
Source: check_circle
Crossref

Immune Checkpoint Inhibitors and Pregnancy: Analysis of the VigiBase® Spontaneous Reporting System

Cancers
2022-12-28 | Journal article
Contributors: Roberta Noseda; Laura Müller; Francesca Bedussi; Michele Fusaroli; Emanuel Raschi; Alessandro Ceschi
Source: check_circle
Crossref
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Preferred source (of 2)‎

Reply to Gremese et al.: Statistical reasoning to evaluate treatment effects when data are collected with lack of design: Covid-19 experience

Proceedings of the National Academy of Sciences
2022-02-15 | Journal article
Contributors: Clelia Di Serio; Pietro Cippà; Alessandro Ceschi; Paolo Ferrari
Source: check_circle
Crossref

Reply to the Letter to the Editor by Kessler Y et al. regarding the manuscript “Safety profile of erenumab, galcanezumab and fremanezumab in pregnancy and lactation: Analysis of the WHO pharmacovigilance database.”

Cephalalgia
2021-09 | Journal article
Contributors: Roberta Noseda; Francesca Bedussi; Claudio Gobbi; Chiara Zecca; Alessandro Ceschi
Source: check_circle
Crossref

Reporting of Acute Inflammatory Neuropathies with COVID-19 Vaccines: Subgroup Disproportionality Analyses in VigiBase

Vaccines
2021-09-14 | Journal article
Contributors: Roberta Noseda; Paolo Ripellino; Sara Ghidossi; Raffaela Bertoli; Alessandro Ceschi
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Diabetes and Overweight/Obesity Are Independent, Nonadditive Risk Factors for In-Hospital Severity of COVID-19: An International, Multicenter Retrospective Meta-analysis

Diabetes Care
2021-06 | Journal article
Part of ISSN: 0149-5992
Part of ISSN: 1935-5548
Source: Self-asserted source
Alessandro Ceschi

Safety profile of erenumab, galcanezumab and fremanezumab in pregnancy and lactation: Analysis of the WHO pharmacovigilance database

Cephalalgia
2021-06 | Journal article
Contributors: Roberta Noseda; Francesca Bedussi; Claudio Gobbi; Chiara Zecca; Alessandro Ceschi
Source: check_circle
Crossref

The statistical risk of diagnosing coincidental acquired hemophilia A following anti‐SARS‐CoV‐2 vaccination

Journal of Thrombosis and Haemostasis
2021-06-26 | Journal article
Part of ISSN: 1538-7933
Part of ISSN: 1538-7836
Source: Self-asserted source
Alessandro Ceschi

Concentrations of Seven Phthalate Monoesters in Infants and Toddlers Quantified in Urine Extracted from Diapers

International Journal of Environmental Research and Public Health
2021-06-24 | Journal article
Contributors: Fiorella Lucarini; Marc Blanchard; Tropoja Krasniqi; Nicolas Duda; Gaëlle Bailat Rosset; Alessandro Ceschi; Nicolas Roth; Nancy B. Hopf; Marie-Christine Broillet; Davide Staedler
Source: check_circle
Crossref
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Preferred source (of 2)‎

Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2

Science
2021-06-18 | Journal article
Part of ISSN: 0036-8075
Part of ISSN: 1095-9203
Source: Self-asserted source
Alessandro Ceschi

False‐positive urine screen test for MDMA in a patient exposed to mebeverine

British Journal of Clinical Pharmacology
2021-05 | Journal article
Contributors: Francesca Bedussi; Elisabetta Acerbis; Roberta Noseda; Davide Demagistri; Emanuela Zamprogno; Alessandro Ceschi
Source: check_circle
Crossref

The Contribution of Clinical Pharmacologists in Precision Medicine: An Opportunity for Health Care Improvement

Current Therapeutic Research
2021-04 | Journal article
Contributors: Davide Grisafi; Alessandro Ceschi; Veronica Avalos Clerici; Francesco Scaglione
Source: check_circle
Crossref

Pros and Cons in Using Population-Based Registers for Assessing the Fetal Safety of Drugs

JAMA Pediatrics
2021-04-01 | Journal article
Part of ISSN: 2168-6203
Source: Self-asserted source
Alessandro Ceschi

Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity

Cell
2021-03 | Journal article
Part of ISSN: 0092-8674
Source: Self-asserted source
Alessandro Ceschi

Isotonitazene: Fatal intoxication in three cases involving this unreported novel psychoactive substance in Switzerland

Forensic Science International
2021-03 | Journal article
Contributors: F. Mueller; C. Bogdal; B. Pfeiffer; L. Andrello; A. Ceschi; A. Thomas; E. Grata
Source: check_circle
Crossref

Adverse Event Reporting with Immune Checkpoint Inhibitors in Older Patients: Age Subgroup Disproportionality Analysis in VigiBase

Cancers
2021-03-06 | Journal article
Contributors: Roberta Noseda; Giulia Bonaldo; Domenico Motola; Anastasios Stathis; Alessandro Ceschi
Source: check_circle
Crossref
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Risk assessment and seroprevalence of SARS-CoV-2 infection in healthcare workers of COVID-19 and non-COVID-19 hospitals in Southern Switzerland

The Lancet Regional Health - Europe
2021-02 | Journal article
Part of ISSN: 2666-7762
Source: Self-asserted source
Alessandro Ceschi

MDMA-related presentations to the emergency departments of the European Drug Emergencies Network plus (Euro-DEN Plus) over the four-year period 2014–2017

Clinical Toxicology
2021-02-01 | Journal article
Part of ISSN: 1556-3650
Part of ISSN: 1556-9519
Source: Self-asserted source
Alessandro Ceschi

A data-driven approach to identify risk profiles and protective drugs in COVID-19

Proceedings of the National Academy of Sciences
2021-01-05 | Journal article
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Alessandro Ceschi

Diabetes mellitus is a risk factor for prolonged SARS-CoV-2 viral shedding in lower respiratory tract samples of critically ill patients

Endocrine
2020-12 | Journal article
Part of ISSN: 1355-008X
Part of ISSN: 1559-0100
Source: Self-asserted source
Alessandro Ceschi

Evaluation of the safety profile of rotavirus vaccines: a pharmacovigilance analysis on American and European data

Scientific Reports
2020-12 | Journal article
Part of ISSN: 2045-2322
Source: Self-asserted source
Alessandro Ceschi

Clinical characteristics and management of a liver transplanted patient admitted with SARS-CoV-2 infection

Clinics and Research in Hepatology and Gastroenterology
2020-11 | Journal article
Part of ISSN: 2210-7401
Source: Self-asserted source
Alessandro Ceschi

Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology

Cell
2020-11 | Journal article
Part of ISSN: 0092-8674
Source: Self-asserted source
Alessandro Ceschi

Pre-Existing Cardiovascular Conditions as Clinical Predictors of Myocarditis Reporting with Immune Checkpoint Inhibitors: A VigiBase Study

Cancers
2020-11-23 | Journal article
Contributors: Roberta Noseda; Lorenzo Ruinelli; Linda C. van der Gaag; Alessandro Ceschi
Source: check_circle
Crossref
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Off‐label use of quetiapine in nursing homes: Does medical specialty of prescribing physicians play a role?

British Journal of Clinical Pharmacology
2020-07 | Journal article
Part of ISSN: 0306-5251
Part of ISSN: 1365-2125
Source: Self-asserted source
Alessandro Ceschi

Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database

Frontiers in Pharmacology
2020-05-04 | Journal article
Part of ISSN: 1663-9812
Source: Self-asserted source
Alessandro Ceschi

Peer‐pressure and overuse: The effect of a multimodal approach on variation in benzodiazepine prescriptions in a network of public hospitals

International Journal of Clinical Practice
2020-03 | Journal article
Part of ISSN: 1368-5031
Part of ISSN: 1742-1241
Source: Self-asserted source
Alessandro Ceschi

Haemophagocytic lymphohistiocytosis in patients treated with immune checkpoint inhibitors: Analysis of WHO global database of individual case safety reports

Journal for ImmunoTherapy of Cancer
2019 | Journal article
EID:

2-s2.0-85065198961

Contributors: Noseda, R.; Bertoli, R.; Müller, L.; Ceschi, A.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Prevalence, clinical relevance and predictive factors of medication discrepancies revealed by medication reconciliation at hospital admission: Prospective study in a Swiss internal medicine ward

BMJ Open
2019 | Journal article
EID:

2-s2.0-85066626512

Contributors: Giannini, O.; Rizza, N.; Pironi, M.; Parlato, S.; Waldispühl Suter, B.; Borella, P.; Pagnamenta, A.; Fishman, L.; Ceschi, A.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Severe rosuvastatin accumulation with rhabdomyolysis due to drug interactions and low cardiac output syndrome

British Journal of Clinical Pharmacology
2019 | Journal article
EID:

2-s2.0-85065301205

Contributors: Previsdomini, M.; Graziano, E.; Decosterd, L.; Courlet, P.; Perren, A.; Ceschi, A.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Unexpected Increase in Benzodiazepine Prescriptions Related to the Introduction of an Electronic Prescribing Tool: Evidence from Multicenter Hospital Data

Diagnostics
2019-11-15 | Journal article
Contributors: Rosaria Del Giorno; Carmen Schneiders; Kevyn Stefanelli; Alessandro Ceschi; Sandor Gyoerik-Lora; Irene Aletto; Luca Gabutti
Source: check_circle
Crossref
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Preferred source (of 4)‎

Emergency department presentations related to acute toxicity following recreational use of cannabis products in Switzerland.

Drug and alcohol dependence
2019-11-07 | Journal article
Source: Self-asserted source
Alessandro Ceschi

C-Reactive Protein and Procalcitonin in Case Reports of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome

International Archives of Allergy and Immunology
2018 | Journal article
EID:

2-s2.0-85045312613

Contributors: Hübner, S.T.; Bertoli, R.; Rätz Bravo, A.E.; Schaueblin, M.; Haschke, M.; Scherer, K.; Ceschi, A.; Leuppi-Taegtmeyer, A.B.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Chronic conditions and multimorbidity in a primary care population: a study in the Swiss Sentinel Surveillance Network (Sentinella)

International Journal of Public Health
2018 | Journal article
EID:

2-s2.0-85047175946

Contributors: Gnädinger, M.; Herzig, L.; Ceschi, A.; Conen, D.; Staehelin, A.; Zoller, M.; Puhan, M.A.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Combining prescription monitoring, benchmarking, and educational interventions to reduce benzodiazepine prescriptions among internal medicine inpatients; a multicenter before and after study in a network of Swiss Public Hospitals

Postgraduate Medicine
2018 | Journal article
EID:

2-s2.0-85052124086

Contributors: Del Giorno, R.; Greco, A.; Zasa, A.; Clivio, L.; Pironi, M.; Ceschi, A.; Gabutti, L.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Identification and Quantification of Thujone in a Case of Poisoning Due to Repeated Ingestion of an Infusion of Artemisia Vulgaris L.

Journal of Food Science
2018 | Journal article
EID:

2-s2.0-85051413466

Contributors: Di Lorenzo, C.; Ferretti, F.; Moro, E.; Ceschi, A.; Colombo, F.; Frigerio, G.; Lüde, S.; Restani, P.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Multifaceted intervention to curb in-hospital over-prescription of proton pump inhibitors: A longitudinal multicenter quasi-experimental before-and-after study

European Journal of Internal Medicine
2018 | Journal article
EID:

2-s2.0-85038939150

Contributors: Del Giorno, R.; Ceschi, A.; Pironi, M.; Zasa, A.; Greco, A.; Gabutti, L.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Reconsidering clinical pharmacology frameworks as a necessary strategy for improving the health care of patients: a systematic review

European Journal of Clinical Pharmacology
2018 | Journal article
EID:

2-s2.0-85049879831

Contributors: Grisafi, D.; Ceschi, A.; Sava, G.; Avalos Clerici, V.; Scaglione, F.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Reporting of immune checkpoint inhibitor-associated myocarditis

The Lancet
2018 | Journal article
EID:

2-s2.0-85050883381

Contributors: Noseda, R.; Magro, L.; Stathis, A.; Ceschi, A.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Benzodiazepines in elderly patients: The dark side of a magic pill,Benzodiazépines chez les patients âgés: le côté sombre d'une pilule magique

Revue Medicale Suisse
2017 | Journal article
EID:

2-s2.0-85014348114

Contributors: Del Giorno, R.; Ceschi, A.; Gabutti, L.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Medication incidents in primary care medicine: A prospective study in the Swiss Sentinel Surveillance Network (Sentinella)

BMJ Open
2017 | Journal article
EID:

2-s2.0-85026414249

Contributors: Gnädinger, M.; Conen, D.; Herzig, L.; Puhan, M.A.; Staehelin, A.; Zoller, M.; Ceschi, A.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Adverse Effects of Plant Food Supplements and Plants Consumed as Food: Results from the Poisons Centres-Based PlantLIBRA Study

Phytotherapy Research
2016 | Journal article
EID:

2-s2.0-84960153373

Contributors: Lüde, S.; Vecchio, S.; Sinno-Tellier, S.; Dopter, A.; Mustonen, H.; Vucinic, S.; Jonsson, B.; Müller, D.; Veras Gimenez Fruchtengarten, L.; Hruby, K. et al.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Adverse effects of plant food supplements self-reported by consumers in the PlantLIBRA survey involving six european countries

PLoS ONE
2016 | Journal article
EID:

2-s2.0-84960539055

Contributors: Restani, P.; Di Lorenzo, C.; Garcia-Alvarez, A.; Badea, M.; Ceschi, A.; Egan, B.; Dima, L.; Lüde, S.; Maggi, F.M.; Marculescu, A. et al.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier

Lifestyle factors, psychiatric and neurologic comorbidities, and drug use associated with incident seizures among adult patients with depression: a population-based nested case–control study

European Journal of Epidemiology
2016 | Journal article
EID:

2-s2.0-84965082138

Contributors: Bloechliger, M.; Ceschi, A.; Rüegg, S.; Jick, S.S.; Meier, C.R.; Bodmer, M.
Source: Self-asserted source
Alessandro Ceschi via Scopus - Elsevier
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