Personal information

Emails & domains

Verified email domains

Websites & social links

Google Scholar
Karolinska Institutet
Lab webpage

Other IDs

Scopus Author ID: 55702234000
Loop profile: 1278263

Keywords

Host-pathogen interactions, infection biology, immunology

Countries

Sweden

Biography

Dr. Karthik is a Scientist and Principal Investigator at Rajiv Gandhi Centre for Biotechnology, Trivandrum. Dr. Karthik's lab at RGCB works on host-pathogen interactions in pneumococcal diseases

Activities

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Employment (4)

Rajiv Gandhi Centre for Biotechnology: Thiruvananthapuram, IN

2025-01-06 to present | Scientist E-1 (Pathogen Biology)
Employment
Source: Self-asserted source
Karthik Subramanian

Rajiv Gandhi Centre for Biotechnology: Thiruvananthapuram, Kerala, IN

2020-12-11 to present | Scientist C (Pathogen Biology)
Employment
Source: Self-asserted source
Karthik Subramanian

Karolinska Institutet: Stockholm, Stockholm County, SE

2014-05 to present | Postdoctoral fellow (Microbiology, Tumor and Cell Biology)
Employment
Source: Self-asserted source
Karthik Subramanian

Karolinska Institute: Stockholm, SE

2020-04-01 to 2020-09-01 | Assistant Professor (Microbiology Tumor and Cell Biology)
Employment
Source: Self-asserted source
Karthik Subramanian

Education and qualifications (3)

Karolinska Institute: Stockholm, SE

2014-05-01 to 2020-03-01 | Postdoctoral fellow (Microbiology Tumor and Cell Biology)
Qualification
Source: Self-asserted source
Karthik Subramanian

National University of Singapore: Singapore, SG

2009-05 to 2013-12 | PhD (Department of Biological Sciences)
Education
Source: Self-asserted source
Karthik Subramanian

SASTRA University: Thanjavur, Tamil Nadu, IN

2005-05 to 2009-04 | Bachelor of Technology (School of Biotechnology)
Education
Source: Self-asserted source
Karthik Subramanian

Professional activities (4)

Scandinavian Society for Immunology: Stockholm, SE

2019-04 to present
Membership
Source: Self-asserted source
Karthik Subramanian

Rajiv Gandhi Centre for Biotechnology: Thiruvananthapuram, Kerala, IN

2021-06-01 | Ramalingaswami Re-entry fellowship (Pathogen Biology)
Distinction
Source: Self-asserted source
Karthik Subramanian

Rajiv Gandhi Centre for Biotechnology: Thiruvananthapuram, Kerala, IN

2020-12-01 | INSPIRE Faculty award (Pathogen Biology)
Distinction
Source: Self-asserted source
Karthik Subramanian

Karolinska Institute: Stockholm, SE

2018-12-01 | Best Scientific paper of the year award (Nature Microbiology) (Microbiology Tumor and Cell Biology)
Distinction
Source: Self-asserted source
Karthik Subramanian

Funding (3)

Disarming bacterial pathogens using novel peptides that target pore-forming toxins: from in silico to in vivo

Award
Department of Science & Technology, India (Delhi, IN)
GRANT_NUMBER:

DST/INSPIRE/04/2019/002238
Source: Self-asserted source
Karthik Subramanian

Investigating pneumococcal adaptation to intracellular survival within the host and characterization of macrophage extracellular vesicles for novel vaccine development.

Award
Department of Biotechnology, India (Delhi, IN)
GRANT_NUMBER:

BT/RLF/Re-entry/46/2020
Source: Self-asserted source
Karthik Subramanian

Unravelling bacterial immunoevasion and host immune reprogramming strategies in invasive pneumococcal diseases

Grant
Science and Engineering Research Board (Delhi, IN)
GRANT_NUMBER:

SRG/2021/000401
Source: Self-asserted source
Karthik Subramanian

Works (12)

Bacterial pore-forming toxin pneumolysin drives pathogenicity through host extracellular vesicles released during infection

iScience
2024-08 | Journal article | Author
DOI: 10.1016/j.isci.2024.110589
Part of ISSN: 2589-0042
Contributors: Saba Parveen; Chinmayi V. Bhat; Aswathy C. Sagilkumar; Shaheena Aziz; J. Arya; Asmita Dutta; Somit Dutta; Sautan Show; Kuldeep Sharma; Sumit Rakshit et al.
Source: Self-asserted source
Karthik Subramanian

Editorial: Deceiving the host: mechanisms of immune evasion and survival by pneumococcal bacteria

Frontiers in Cellular and Infection Microbiology
2023-06-19 | Journal article
DOI: 10.3389/fcimb.2023.1231253
Part of ISSN: 2235-2988
Contributors: Karthik Subramanian; Anirban Banerjee
Source: Self-asserted source
Karthik Subramanian
grade
Preferred source (of 2)‎

Emerging Roles of Extracellular Vesicles in Pneumococcal Infections: Immunomodulators to Potential Novel Vaccine Candidates.

Frontiers in cellular and infection microbiology
2022-02-14 | Journal article
DOI: 10.3389/fcimb.2022.836070
PMID: 35237534
PMC: PMC8882830
Source: Self-asserted source
Karthik Subramanian

Mannose receptor‐derived peptides neutralize pore‐forming toxins and reduce inflammation and development of pneumococcal disease

EMBO Molecular Medicine
2020-11-06 | Journal article
DOI: 10.15252/emmm.202012695
Contributors: Karthik Subramanian; Federico Iovino; Vasiliki Tsikourkitoudi; Padryk Merkl; Sultan Ahmed; Samuel B Berry; Marie‐Stephanie Aschtgen; Mattias Svensson; Peter Bergman; Georgios A Sotiriou et al.
Source: check_circle
Crossref

Emerging concepts in the pathogenesis of the Streptococcus pneumoniae : From nasopharyngeal colonizer to intracellular pathogen

Cellular Microbiology
2019-11-17 | Journal article
DOI: 10.1111/cmi.13077
Contributors: Karthik Subramanian; Birgitta Henriques‐Normark; Staffan Normark
Source: check_circle
Crossref

Genomic Characterization of the Emerging Pathogen Streptococcus pseudopneumoniae.

mBio
2019-06-25 | Journal article
DOI: 10.1128/mBio.01286-19
PMID: 31239383
PMC: PMC6593409
Source: Self-asserted source
Karthik Subramanian

Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival

Nature microbiology
2018-11-12 | Journal article
DOI: 10.1038/s41564-018-0280-x
Source: Self-asserted source
Karthik Subramanian
grade
Preferred source (of 2)‎

Vitamin D Promotes Pneumococcal Killing and Modulates Inflammatory Responses in Primary Human Neutrophils

Journal of Innate Immunity
2017 | Journal article
DOI: 10.1159/000455969
EID:

2-s2.0-85014130015
Contributors: Subramanian, K.; Bergman, P.; Henriques-Normark, B.
Source: Self-asserted source
Karthik Subramanian via Scopus - Elsevier

Cinobufagin modulates human innate immune responses and triggers antibacterial activity

PLoS ONE
2016 | Journal article
DOI: 10.1371/journal.pone.0160734
EID:

2-s2.0-84984829179
Contributors: Xie, S.; Spelmink, L.; Codemo, M.; Subramanian, K.; Pütsep, K.; Henriques-Normark, B.; Olliver, M.
Source: Self-asserted source
Karthik Subramanian via Scopus - Elsevier

Preferential silent survival of intracellular bacteria in hemoglobin-primed macrophages

Journal of Innate Immunity
2014 | Journal article
DOI: 10.1159/000358236
EID:

2-s2.0-84902778231
Contributors: Subramanian, K.; Winarsih, I.; Keerthani, C.; Ho, B.; Ding, J.L.
Source: Self-asserted source
Karthik Subramanian via Scopus - Elsevier

CD163 and IgG codefend against cytotoxic hemoglobin via autocrine and paracrine mechanisms

Journal of Immunology
2013 | Journal article
DOI: 10.4049/jimmunol.1202648
EID:

2-s2.0-84877836304
Contributors: Subramanian, K.; Du, R.; Tan, N.S.; Ho, B.; Ding, J.L.
Source: Self-asserted source
Karthik Subramanian via Scopus - Elsevier

Biosynthesis of Silver Nanoparticles by Aspergillus niger

Asian Journal of Research in Chemistry
2011-01 | Journal article
Source: Self-asserted source
Karthik Subramanian

Peer review (5 reviews for 3 publications/grants)

Review activity for ACS infectious diseases. (3)
Review activity for Brazilian journal of microbiology. (1)
Review activity for npj vaccines. (1)
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