Personal information

Activities

Employment (4)

Princeton University: Princeton, NJ, US

2017-06-01 to present | Professor (Lewis Sigler Institute)
Employment
Source: Self-asserted source
Joshua Akey

University of Washington: Seattle, WA, US

2014 to 2017 | Professor (Department of Genome Sciences)
Employment
Source: Self-asserted source
Joshua Akey

University of Washington: Seattle, WA, US

2010 to 2014 | Associate Professor (Department of Genome Sciences)
Employment
Source: Self-asserted source
Joshua Akey

University of Washington: Seattle, Washington, US

2004 to 2010 | Assistant Professor (Department of Genome Sciences)
Employment
Source: Self-asserted source
Joshua Akey

Education and qualifications (3)

Fred Hutchinson Cancer Research Center: Seattle, WA, US

2002 to 2004 | Postdoctoral Research Associate (Computational Biology)
Education
Source: Self-asserted source
Joshua Akey

University of Texas-Houston: Houston, TX, US

1998 to 2002 | PhD (Genetics)
Education
Source: Self-asserted source
Joshua Akey

University of Pittsburgh: Pittsburgh, PA, US

1994 to 1998 | BS (Molecular Biology)
Education
Source: Self-asserted source
Joshua Akey

Professional activities (20)

Genetics: NY, NY, US

2013 to present | Editorial Board
Invited position
Source: Self-asserted source
Joshua Akey

Molecular Biology and Genetics: London, GB

2012 to present | Editorial Board
Invited position
Source: Self-asserted source
Joshua Akey

PLoS Genetics: Cambridge, GB

2010 to present | Editorial Board
Invited position
Source: Self-asserted source
Joshua Akey

Statistical Genetics Training Faculty, U of WA: Seattle, WA, US

2007 to present
Membership
Source: Self-asserted source
Joshua Akey

Genome Research: Cold Spring Harbor, NY, US

2006 to present | Editorial Board
Invited position
Source: Self-asserted source
Joshua Akey

Computational and Molecular Biology Interdisciplinary Committee, University of Washington: Seattle, WA, US

2005 to present | Affiliate Member
Membership
Source: Self-asserted source
Joshua Akey

American Society of Human Genetics Meeting: Rockville, MD, US

2012 to 2015 | Program Committee
Invited position
Source: Self-asserted source
Joshua Akey

William King Society: NUI-Galway, IE

2014 | William King Medal for work in Archaic Genomics
Distinction
Source: Self-asserted source
Joshua Akey

University of Texas-Houston: Houston, TX, US

2014 | Distinguished Alumnus Speaker
Distinction
Source: Self-asserted source
Joshua Akey

American Journal of Human Genetics: Cambridge, MA, US

2010 to 2014 (Editorial Board)
Invited position
Source: Self-asserted source
Joshua Akey

School of Medicine, University of Washington: Seattle, WA, US

2013 | Science in Medicine Lecture
Distinction
Source: Self-asserted source
Joshua Akey

Aflred P. Sloan Foundation: NY, NY, US

2007 | Aflred P. Sloan Research Fellowship in Computational Biology
Distinction
Source: Self-asserted source
Joshua Akey

Genome Technology Magazine: NY, NY, US

2006 | Up and Coming Young Investigators
Distinction
Source: Self-asserted source
Joshua Akey

National Science Foundation: Washington, DC, US

2003 | Postdoctoral Fellowship in Interdisciplinary Informatics
Distinction
Source: Self-asserted source
Joshua Akey

ThermoHybaid: Franklin, MA, US

1999 to 2002 | Consultant
Invited position
Source: Self-asserted source
Joshua Akey

Human Genetics Center, University of Texas-Houston: Houston, TX, US

1998 to 2002 | Graduate Research Assistant
Invited position
Source: Self-asserted source
Joshua Akey

Rockefeller University: NY, NY, US

1999 | Travel Fellowship, Advanced Linkage Analysis Course
Distinction
Source: Self-asserted source
Joshua Akey

Graduate School of Biomedical Sciences, University of Texas-Houston: Houston, TX, US

1999 | Schissler Fellowship
Distinction
Source: Self-asserted source
Joshua Akey

Graduate School of Biomedical Sciences, University of Texas-Houston: Houston, TX, US

1998 | Presidential Fellowship
Distinction
Source: Self-asserted source
Joshua Akey

Department of Human Genetics, University of Pittsburgh: Pittsburgh, PA, US

1994 to 1998 | Research Associate
Invited position
Source: Self-asserted source
Joshua Akey

Works (50 of 167)

Items per page:
Page 1 of 4

Recurrent gene flow between Neanderthals and modern humans over the past 200,000 years

Science
2024-07-12 | Journal article
Contributors: Liming Li; Troy J. Comi; Rob F. Bierman; Joshua M. Akey
Source: check_circle
Crossref

Lifetime prevalence of owner-reported medical conditions in the 25 most common dog breeds in the Dog Aging Project pack.

Frontiers in veterinary science
2023-11 | Journal article
Contributors: Forsyth KK; McCoy BM; Schmid SM; Promislow DEL; Snyder-Mackler N; DAP Consortium; Creevy KE
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Social determinants of health and disease in companion dogs: a cohort study from the Dog Aging Project.

Evolution, medicine, and public health
2023-05 | Journal article
Contributors: McCoy BM; Brassington L; Jin K; Dolby GA; Shrager S; Collins D; Dunbar M; Dog Aging Project Consortium ; Ruple A; Snyder-Mackler N
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Banking on a new understanding: translational opportunities from veterinary biobanks.

GeroScience
2023-03 | Journal article
Contributors: LaLonde-Paul D; Mouttham L; Dog Aging Project Consortium; Promislow DEL; Castelhano MG
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Age and Physical Activity Levels in Companion Dogs: Results From the Dog Aging Project.

The journals of gerontology. Series A, Biological sciences and medical sciences
2022-10 | Journal article
Contributors: Lee H; Collins D; Creevy KE; Promislow DEL; Dog Aging Project Consortium
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

The contribution of Neanderthal introgression to modern human traits.

Current biology : CB
2022-09 | Journal article
Contributors: Reilly PF; Tjahjadi A; Miller SL; Akey JM; Tucci S
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Associations between physical activity and cognitive dysfunction in older companion dogs: results from the Dog Aging Project.

GeroScience
2022-09-21 | Journal article
Contributors: Emily Bray; David Raichlen; Forsyth KK; Daniel Promislow; Alexander GE; Evan MacLean; Dog Aging Project Consortium
Source: Self-asserted source
Joshua Akey

Evaluation of cognitive function in the Dog Aging Project: associations with baseline canine characteristics.

Scientific reports
2022-08 | Journal article
Contributors: Yarborough S; Fitzpatrick A; Schwartz SM; Dog Aging Project Consortium
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Evolution of Human-Specific Alleles Protecting Cognitive Function of Grandmothers.

Molecular biology and evolution
2022-08 | Journal article
Contributors: Saha S; Khan N; Comi T; Verhagen A; Sasmal A; Diaz S; Yu H; Chen X; Akey JM; Frank M et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Author Correction: An open science study of ageing in companion dogs

Nature
2022-08-25 | Journal article
Contributors: Kate E. Creevy; Joshua M. Akey; Matt Kaeberlein; Daniel E. L. Promislow; Brian G. Barnett; Brooke Benton; Elhanan Borenstein; Marta G. Castelhano; Lucy Chou; Devin Collins et al.
Source: check_circle
Crossref

Demographic factors associated with joint supplement use in dogs from the Dog Aging Project.

Frontiers in veterinary science
2022-07-26 | Journal article
Contributors: Hoffman JM; Tolbert MK; Promislow DEL; Dog Aging Project Consortium
Source: Self-asserted source
Joshua Akey
grade
Preferred source (of 2)‎

Once-daily feeding is associated with better health in companion dogs: results from the Dog Aging Project.

GeroScience
2022-04 | Journal article
Contributors: Bray EE; Zheng Z; Tolbert MK; McCoy BM; Dog Aging Project Consortium; Kaeberlein M; Kerr KF
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

An open science study of ageing in companion dogs.

Nature
2022-02 | Journal article
Contributors: Creevy KE; Akey JM; Kaeberlein M; Promislow DEL; Dog Aging Project Consortium
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Deep sequencing of 1320 genes reveals the landscape of protein-truncating variants and their contribution to psoriasis in 19,973 Chinese individuals.

Genome research
2021-06 | Journal article
Contributors: Xu H; Zhen Q; Bai M; Fang L; Zhang Y; Li B; Ge H; Moon S; Chen W; Fu W et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease.

Cell
2021-04 | Journal article
Contributors: de Goede OM; Nachun DC; Ferraro NM; Gloudemans MJ; Rao AS; Smail C; Eulalio TY; Aguet F; Ng B; Xu J et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

A Quantitative Proteome Map of the Human Body.

Cell
2020-09 | Journal article
Contributors: Jiang L; Wang M; Lin S; Jian R; Li X; Chan J; Dong G; Fang H; Robinson AE; GTEx Consortium et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

A vast resource of allelic expression data spanning human tissues.

Genome biology
2020-09 | Journal article
Contributors: Castel SE; Aguet F; Mohammadi P; GTEx Consortium; Ardlie KG; Lappalainen T
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Cell type-specific genetic regulation of gene expression across human tissues.

Science (New York, N.Y.)
2020-09 | Journal article
Contributors: Kim-Hellmuth S; Aguet F; Oliva M; Muñoz-Aguirre M; Kasela S; Wucher V; Castel SE; Hamel AR; Viñuela A; Roberts AL et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

The GTEx Consortium atlas of genetic regulatory effects across human tissues.

Science (New York, N.Y.)
2020-09 | Journal article
Contributors: GTEx Consortium
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Editorial overview: Evolutionary genomics - from molecular mechanisms to phenotypes to populations.

Current opinion in genetics & development
2020-06 | Journal article
Contributors: Akey J; Tishkoff S
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Implications of localized charge for human influenza A H1N1 hemagglutinin evolution: Insights from deep mutational scans

PLOS Computational Biology
2020-06-25 | Journal article
Contributors: Chadi M. Saad-Roy; Rustom Antia; Nimalan Arinaminpathy; Ned S. Wingreen; Simon A. Levin; Joshua M. Akey; Bryan T. Grenfell
Source: check_circle
Crossref

Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals.

Cell
2020-01 | Journal article
Contributors: Chen L; Wolf AB; Fu W; Li L; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

The long walk to African genomics

Genome Biology
2019-12 | Journal article
Contributors: Serena Tucci; Joshua M. Akey
Source: check_circle
Crossref

Rare loss of function variants in candidate genes and risk of colorectal cancer.

Human genetics
2018-09 | Journal article
Contributors: Rosenthal EA; Shirts BH; Amendola LM; Horike-Pyne M; Robertson PD; Hisama FM; Bennett RL; Dorschner MO; Nickerson DA; Stanaway IB et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia.

Science (New York, N.Y.)
2018-08 | Journal article
Contributors: Tucci S; Vohr SH; McCoy RC; Vernot B; Robinson MR; Barbieri C; Nelson BJ; Fu W; Purnomo GA; Sudoyo H et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Massive variation of short tandem repeats with functional consequences across strains of <i>Arabidopsis thaliana</i>.

Genome research
2018-07 | Journal article
Contributors: Press MO; McCoy RC; Hall AN; Akey JM; Queitsch C
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Outstanding questions in the study of archaic hominin admixture.

PLoS genetics
2018-05 | Journal article
Contributors: Wolf AB; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Evolution of DNAase I Hypersensitive Sites in MHC Regulatory Regions of Primates.

Genetics
2018-04 | Journal article
Contributors: Jin Y; Gittelman RM; Lu Y; Liu X; Li MD; Ling F; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Analysis of Human Sequence Data Reveals Two Pulses of Archaic Denisovan Admixture.

Cell
2018-03 | Journal article
Contributors: Browning SR; Browning BL; Zhou Y; Tucci S; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Co-expression networks reveal the tissue-specific regulation of transcription and splicing.

Genome research
2017-10 | Journal article
Contributors: Saha A; Kim Y; Gewirtz ADH; Jo B; Gao C; McDowell IC; GTEx Consortium; Engelhardt BE; Battle A
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Dynamic landscape and regulation of RNA editing in mammals.

Nature
2017-10 | Journal article
Contributors: Tan MH; Li Q; Shanmugam R; Piskol R; Kohler J; Young AN; Liu KI; Zhang R; Ramaswami G; Ariyoshi K et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease.

Nature genetics
2017-10 | Journal article
Contributors: eGTEx Project
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Genetic effects on gene expression across human tissues.

Nature
2017-10 | Journal article
Contributors: GTEx Consortium; Laboratory; Data Analysis &Coordinating Center (LDACC)—Analysis Working Group; Statistical Methods groups—Analysis Working Group; Montgomery SB
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Identifying <i>cis</i>-mediators for <i>trans</i>-eQTLs across many human tissues using genomic mediation analysis.

Genome research
2017-10 | Journal article
Contributors: Yang F; Wang J; GTEx Consortium; Pierce BL; Chen LS
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Landscape of X chromosome inactivation across human tissues.

Nature
2017-10 | Journal article
Contributors: Tukiainen T; Villani AC; Yen A; Rivas MA; Marshall JL; Satija R; Aguirre M; Gauthier L; Fleharty M; Kirby A et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

The impact of rare variation on gene expression across tissues.

Nature
2017-10 | Journal article
Contributors: Li X; Kim Y; Tsang EK; Davis JR; Damani FN; Chiang C; Hess GT; Zappala Z; Strober BJ; Scott AJ et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Selection plays the hand it was dealt: evidence that human adaptation commonly targets standing genetic variation.

Genome biology
2017-08 | Journal article
Contributors: McCoy RC; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome.

Scientific reports
2017-04 | Journal article
Contributors: Johnston HR; Hu YJ; Gao J; O'Connor TD; Abecasis GR; Wojcik GL; Gignoux CR; Gourraud PA; Lizee A; Hansen M et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression.

Cell
2017-02 | Journal article
Contributors: McCoy RC; Wakefield J; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Tracing the peopling of the world through genomics.

Nature
2017-01 | Journal article
Contributors: Nielsen R; Akey JM; Jakobsson M; Pritchard JK; Tishkoff S; Willerslev E
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Human RECQ Helicase Pathogenic Variants, Population Variation and "Missing" Diseases.

Human mutation
2016-12 | Journal article
Contributors: Fu W; Ligabue A; Rogers KJ; Akey JM; Monnat RJ
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Archaic Hominin Admixture Facilitated Adaptation to Out-of-Africa Environments.

Current biology : CB
2016-11 | Journal article
Contributors: Gittelman RM; Schraiber JG; Vernot B; Mikacenic C; Wurfel MM; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Editorial overview: Genetics of human origin: New horizons in human population genetics.

Current opinion in genetics & development
2016-11 | Journal article
Contributors: Akey JM; Di Rienzo A
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.

Nature communications
2016-10 | Journal article
Contributors: Mathias RA; Taub MA; Gignoux CR; Fu W; Musharoff S; O'Connor TD; Vergara C; Torgerson DG; Pino-Yanes M; Shringarpure SS et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry.

Nature communications
2016-10 | Journal article
Contributors: Kessler MD; Yerges-Armstrong L; Taub MA; Shetty AC; Maloney K; Jeng LJB; Ruczinski I; Levin AM; Williams LK; Beaty TH et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Detecting Sources of Transcriptional Heterogeneity in Large-Scale RNA-Seq Data Sets.

Genetics
2016-10 | Journal article
Contributors: Searle BC; Gittelman RM; Manor O; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Robust Inference of Identity by Descent from Exome-Sequencing Data.

American journal of human genetics
2016-10 | Journal article
Contributors: Fu W; Browning SR; Browning BL; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Population genetics: A map of human wanderlust.

Nature
2016-09 | Journal article
Contributors: Tucci S; Akey JM
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility.

Nature
2016-08 | Journal article
Contributors: Nuttle X; Giannuzzi G; Duyzend MH; Schraiber JG; Narvaiza I; Sudmant PH; Penn O; Chiatante G; Malig M; Huddleston J et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central

Human Diversity in a Cell Surface Receptor that Inhibits Autophagy.

Current biology : CB
2016-06 | Journal article
Contributors: Chaudhary A; Leite M; Kulasekara BR; Altura MA; Ogahara C; Weiss E; Fu W; Blanc MP; O'Keeffe M; Terhorst C et al.
Source: Self-asserted source
Joshua Akey via Europe PubMed Central
Items per page:
Page 1 of 4

Peer review (1 review for 1 publication/grant)

Review activity for Science. (1)