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Scopus Author ID: 55216840200
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Employment (4)

Kansas State University College of Veterinary Medicine: Manhattan, KS, US

2022-12-01 to present | Assistant Professor (Diagnostic Medicine/Pathobiology)
Employment
Source: Self-asserted source
Santosh Dhakal

Johns Hopkins Bloomberg School of Public Health: Baltimore, MD, US

2021-03 to 2022-12-31 | Faculty (Molecular Microbiology and Immunology)
Employment
Source: Self-asserted source
Santosh Dhakal

Johns Hopkins University Bloomberg School of Public Health: Baltimore, MD, US

2018-08-22 to 2021-02-28 | Postdoctoral Fellow (Molecular Microbiology and Immunology)
Employment
Source: Self-asserted source
Santosh Dhakal

National Zoonoses and Food Hygiene Research Center: Kathmandu, NP

2011-08 to 2013-05 | Veterinary Officer/ Researcher (Zoonotic Disease Investigation)
Employment
Source: Self-asserted source
Santosh Dhakal

Education and qualifications (2)

Ohio State University: Columbus, OH, US

2013-06-01 to 2018-08-05 | MS, PhD (Veterinary Preventive Medicine)
Education
Source: Self-asserted source
Santosh Dhakal

Tribhuvan University: Chitwan, NP

2006 to 2011 | B.V.Sc.&A.H. (Veterinary medicine)
Education
Source: Self-asserted source
Santosh Dhakal

Works (50 of 63)

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Page 1 of 2

Estradiol mediates greater germinal center responses to influenza vaccination in female than male mice

mBio
2024-04-10 | Journal article
DOI: 10.1128/mbio.00326-24
Contributors: Santosh Dhakal; Han-Sol Park; Kumba Seddu; John S. Lee; Patrick S. Creisher; Brittany Seibert; Kimberly M. Davis; Isabella R. Hernandez; Robert W. Maul; Sabra L. Klein et al.
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Crossref

Reduced control of SARS-CoV-2 infection associates with lower mucosal antibody responses in pregnancy

mSphere
2024-03 | Journal article
DOI: 10.1128/msphere.00812-23
Contributors: Laura A. St Clair; Raghda E. Eldesouki; Jaiprasath Sachithanandham; Anna Yin; Amary Fall; C. Paul Morris; Julie M. Norton; Omar Abdullah; Santosh Dhakal; Caelan Barranta et al.
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Crossref

Reduced control of SARS-CoV-2 infection is associated with lower mucosal antibody responses in pregnant women

2023-03-20 | Preprint
DOI: 10.1101/2023.03.19.23287456
Contributors: Laura A. St Clair; Raghda E. Eldesouki; Jaiprasath Sachithanandham; Anna Yin; Amary Fall; C. Paul Morris; Julie M. Norton; Michael Forman; Omar Abdullah; Santosh Dhakal et al.
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Crossref

Methodological approaches to optimize multiplex oral fluid SARS-CoV-2 IgG assay performance and correlation with serologic and neutralizing antibody responses

2022-12-26 | Preprint
DOI: 10.1101/2022.12.22.22283858
Contributors: Nora Pisanic; Annukka A. R. Antar; Kate Kruczynski; Magdielis Gregory Rivera; Santosh Dhakal; Kristoffer Spicer; Pranay R. Randad; Andrew Pekosz; Sabra L. Klein; Michael J. Betenbaugh et al.
Source: check_circle
Crossref

The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization

mSphere
2022-08-31 | Journal article
DOI: 10.1128/msphere.00193-22
Contributors: Amy B. Karger; James D. Brien; Jayne M. Christen; Santosh Dhakal; Troy J. Kemp; Sabra L. Klein; Ligia A. Pinto; Lakshmanane Premkumar; John D. Roback; Raquel A. Binder et al.
Source: check_circle
Crossref

Greater Breadth of Vaccine-Induced Immunity in Females than Males Is Mediated by Increased Antibody Diversity in Germinal Center B Cells

mBio
2022-08-30 | Journal article
DOI: 10.1128/mbio.01839-22
Contributors: Rebecca L. Ursin; Santosh Dhakal; Hsuan Liu; Sahana Jayaraman; Han-Sol Park; Harrison R. Powell; Morgan L. Sherer; Kirsten E. Littlefield; Ashley L. Fink; Zexu Ma et al.
Source: check_circle
Crossref

Risk Factors Associated with Avian Influenza Subtype H9 Outbreaks in Poultry Farms of Central Lowland Nepal

Infectious Disease Reports
2022-07-18 | Journal article
DOI: 10.3390/idr14040056
Contributors: Deepak Subedi; Parshuram Phuyal; Suman Bhandari; Milan Kandel; Shambhu Shah; Gaurav Rawal; Surendra Karki; Santosh Dhakal
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Crossref
grade
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Female-biased effects of aging on a chimeric hemagglutinin stalk-based universal influenza virus vaccine in mice

Vaccine
2022-03 | Journal article
DOI: 10.1016/j.vaccine.2020.11.057
Contributors: Santosh Dhakal; Sharvari Deshpande; Meagan McMahon; Shirin Strohmeier; Florian Krammer; Sabra L. Klein
Source: check_circle
Crossref

Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model

mBio
2021-08-31 | Journal article
DOI: 10.1128/mBio.00974-21
Contributors: Santosh Dhakal; Camilo A. Ruiz-Bedoya; Ruifeng Zhou; Patrick S. Creisher; Jason S. Villano; Kirsten Littlefield; Jennie Ruelas Castillo; Paula Marinho; Anne E. Jedlicka; Alvaro A. Ordonez et al.
Source: check_circle
Crossref

A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type and Delta variants

2021-06-28 | Preprint
DOI: 10.1101/2021.06.28.450181
Contributors: Linglei Jiang; Tom A.P. Driedonks; Wouter S.P. Jong; Santosh Dhakal; H. Bart van den Berg van Saparoea; Ioannis Sitaras; Ruifeng Zhou; Christopher Caputo; Kirsten Littlefield; Maggie Lowman et al.
Source: check_circle
Crossref

Sex- and Gender-Based Pharmacological Response to Drugs

Pharmacological Reviews
2021-04 | Journal article
DOI: 10.1124/pharmrev.120.000206
Contributors: Franck Mauvais-Jarvis; Heiner K. Berthold; Ilaria Campesi; Juan-Jesus Carrero; Santosh Dhakal; Flavia Franconi; Ioanna Gouni-Berthold; Mark L. Heiman; Alexandra Kautzky-Willer; Sabra L. Klein et al.
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Crossref

Protective efficacy of an orf virus-vector encoding the hemmagglutinin and the nucleoprotein of influenza A virus in swine

2021-04-21 | Preprint
DOI: 10.1101/2021.04.19.440556
Contributors: Lok R. Joshi; David Knudsen; Pablo Pineyro; Santhosh Dhakal; Gourapura J. Renukaradhya; Diego G. Diel
Source: check_circle
Crossref

Effect of an Adenovirus-Vectored Universal Influenza Virus Vaccine on Pulmonary Pathophysiology in a Mouse Model

Journal of Virology
2021-04-12 | Journal article
DOI: 10.1128/JVI.02359-20
Contributors: Santosh Dhakal; Jeffrey Loube; Julia A. Misplon; Chia-Yun Lo; Patrick S. Creisher; Kathleen R. Mulka; Sharvari Deshpande; Wayne Mitzner; Sabra L. Klein; Suzanne L. Epstein et al.
Source: check_circle
Crossref

Sex differences in lung imaging and SARS-CoV-2 antibody responses in a COVID-19 golden Syrian hamster model

2021-04-04 | Preprint
DOI: 10.1101/2021.04.02.438292
Contributors: Santosh Dhakal; Camilo A. Ruiz-Bedoya; Ruifeng Zhou; Patrick S. Creisher; Jason S. Villano; Kirsten Littlefield; Jennie Ruelas Castillo; Paula Marinho; Anne Jedlicka; Alvaro A. Ordonez et al.
Source: check_circle
Crossref

Durable SARS-CoV-2 B cell immunity after mild or severe disease

Journal of Clinical Investigation
2021-04-01 | Journal article
DOI: 10.1172/JCI145516
Contributors: Clinton O. Ogega; Nicole E. Skinner; Paul W. Blair; Han-Sol Park; Kirsten Littlefield; Abhinaya Ganesan; Santosh Dhakal; Pranay Ladiwala; Annukka A.R. Antar; Stuart C. Ray et al.
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Crossref

Review of rabies in Nepal

One Health
2020 | Journal article
DOI: 10.1016/j.onehlt.2020.100155
Part of ISSN: 2352-7714
Contributors: Saurav Pantha; Deepak Subedi; Uddab Poudel; Sanju Subedi; Krishna Kaphle; Santosh Dhakal
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search

Early Epidemiological Features of COVID-19 in Nepal and Public Health Response

Frontiers in Medicine
2020-08-11 | Journal article
DOI: 10.3389/fmed.2020.00524
Part of ISSN: 2296-858X
Contributors: Santosh Dhakal; Surendra Karki
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search

Androgen receptor signaling in the lungs mitigates inflammation and improves the outcome of influenza in mice

PLOS Pathogens
2020-07-09 | Journal article
DOI: 10.1371/journal.ppat.1008506
Contributors: Landon G. vom Steeg; Paul G. Thomas; Santosh Dhakal; Yishak A. Woldetsadik; Han-Sol Park; Kathleen R. Mulka; Emma C. Reilly; David J. Topham; Sabra L. Klein
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Crossref

Livestock and Poultry Production in Nepal and Current Status of Vaccine Development.

Vaccines
2020-06 | Journal article
DOI: 10.3390/vaccines8020322
PMID: 32575369
Contributors: Poudel U; Dahal U; Upadhyaya N; Chaudhari S; Dhakal S
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Coronaviruses in animals and humans, COVID-19 pandemic and one health approach

Applied Science and Technology Annals
2020-06-30 | Journal article
DOI: 10.3126/asta.v1i1.30305
Contributors: Mahesh K.C.; Shristi Ghimire; Namita Bhattarai; Santosh Dhakal
Source: check_circle
Crossref

Biological sex impacts COVID-19 outcomes

PLOS Pathogens
2020-06-22 | Journal article
DOI: 10.1371/journal.ppat.1008570
Contributors: Sabra L. Klein; Carolyn B. Coyne; Santosh Dhakal; Rebecca L. Ursin; Sharvari Deshpande; Kathryn Sandberg; Franck Mauvais-Jarvis
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Crossref

Chitosan-adjuvanted Salmonella subunit nanoparticle vaccine for poultry delivered through drinking water and feed.

Carbohydrate polymers
2020-05 | Journal article
DOI: 10.1016/j.carbpol.2020.116434
PMID: 32532387
Contributors: Renu S; Han Y; Dhakal S; Lakshmanappa YS; Ghimire S; Feliciano-Ruiz N; Senapati S; Narasimhan B; Selvaraj R; Renukaradhya GJ
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

A Nanoparticle-Poly(I:C) Combination Adjuvant Enhances the Breadth of the Immune Response to Inactivated Influenza Virus Vaccine in Pigs

Vaccines
2020-05-18 | Journal article
DOI: 10.3390/vaccines8020229
Contributors: Sankar Renu; Ninoshkaly Feliciano-Ruiz; Fangjia Lu; Shristi Ghimire; Yi Han; Jennifer Schrock; Santosh Dhakal; Veerupaxagouda Patil; Steven Krakowka; Harm HogenEsch et al.
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Crossref
grade
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<p>Oral Deliverable Mucoadhesive Chitosan-<em>Salmonella</em> Subunit Nanovaccine for Layer Chickens</p>

International Journal of Nanomedicine
2020-02 | Journal article
DOI: 10.2147/IJN.S238445
Contributors: Sankar Renu; Ashley D Markazi; Santosh Dhakal; Yashavanth Shaan Lakshmanappa; Revathi Shanmugasundaram; Ramesh K Selvaraj; Gourapura J Renukaradhya
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Crossref

Poly(I:C) augments inactivated influenza virus-chitosan nanovaccine induced cell mediated immune response in pigs vaccinated intranasally.

Veterinary microbiology
2020-02 | Journal article
DOI: 10.1016/j.vetmic.2020.108611
PMID: 32122615
Contributors: Renu S; Feliciano-Ruiz N; Ghimire S; Han Y; Schrock J; Dhakal S; Patil V; Krakowka S; Renukaradhya GJ
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Nanoparticle-based vaccine development and evaluation against viral infections in pigs

Veterinary Research
2019-11-06 | Journal article
DOI: 10.1186/s13567-019-0712-5
Part of ISSN: 1297-9716
Contributors: Santosh Dhakal; Gourapura J. Renukaradhya
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search

Evaluation of CpG-ODN-adjuvanted polyanhydride-based intranasal influenza nanovaccine in pigs

Veterinary Microbiology
2019-10 | Journal article
DOI: 10.1016/j.vetmic.2019.108401
Part of ISSN: 0378-1135
Contributors: S. Dhakal; S. Ghimire; S. Renu; K.A. Ross; Y.S. Lakshmanappa; B.T. Hogshead; P. Bernardo; C.W. Lee; M.J. Wannemuehler; B. Narasimhan et al.
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search

Protective immunity against influenza virus challenge by norovirus P particle-M2e and HA2-AtCYN vaccines in chickens

Vaccine
2019-10 | Journal article
DOI: 10.1016/j.vaccine.2019.08.082
Part of ISSN: 0264-410X
Contributors: Mohamed Elaish; Ming Xia; John M. Ngunjiri; Amir Ghorbani; Hyesun Jang; Mahesh KC; Michael C. Abundo; Santosh Dhakal; Renukaradhya Gourapura; Xi Jiang et al.
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search
grade
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Host factors impact vaccine efficacy: implications for seasonal and universal influenza vaccine programs.

Journal of virology
2019-08 | Journal article
DOI: 10.1128/jvi.00797-19
PMID: 31391269
Contributors: Dhakal S; Klein SL
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central
grade
Preferred source (of 2)‎

Author Correction: Age-associated changes in the impact of sex steroids on influenza vaccine responses in males and females

npj Vaccines
2019-08-12 | Journal article
DOI: 10.1038/s41541-019-0130-8
Contributors: Tanvi Potluri; Ashley L. Fink; Kristyn E. Sylvia; Santosh Dhakal; Meghan S. Vermillion; Landon vom Steeg; Sharvari Deshpande; Harish Narasimhan; Sabra L. Klein
Source: check_circle
Crossref

Age-associated changes in the impact of sex steroids on influenza vaccine responses in males and females.

NPJ Vaccines
2019-07 | Journal article
DOI: 10.1038/s41541-019-0124-6
PMID: 31312529
PMC: PMC6626024
Contributors: Potluri T; Fink AL; Sylvia KE; Dhakal S; Vermillion MS; Vom Steeg L; Deshpande S; Narasimhan H; Klein SL
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central
grade
Preferred source (of 2)‎

Amish (Rural) vs. non-Amish (Urban) Infant Fecal Microbiotas Are Highly Diverse and Their Transplantation Lead to Differences in Mucosal Immune Maturation in a Humanized Germfree Piglet Model.

Frontiers in Immunology
2019-07 | Journal article
DOI: 10.3389/fimmu.2019.01509
PMID: 31379808
PMC: PMC6648804
Contributors: Dhakal S; Wang L; Antony L; Rank J; Bernardo P; Ghimire S; Bondra K; Siems C; Lakshmanappa YS; Renu S et al.
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Corn-derived alpha-D-glucan nanoparticles as adjuvant for intramuscular and intranasal immunization in pigs.

Nanomedicine : nanotechnology, biology, and medicine
2019-01 | Journal article
DOI: 10.1016/j.nano.2018.12.003
PMID: 30611772
Contributors: Dhakal S; Lu F; Ghimire S; Renu S; Laxmanappa YS; Hogshead BT; Ragland D; HogenEsch H; Renukaradhya GJ
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Surface engineered polyanhydride-based oral Salmonella subunit nanovaccine for poultry.

International journal of nanomedicine
2018-11 | Journal article
DOI: 10.2147/IJN.S185588
PMID: 30555234
PMC: PMC6280892
Contributors: Renu S; Markazi AD; Dhakal S; Lakshmanappa YS; Gourapura SR; Shanmugasundaram R; Senapati S; Narasimhan B; Selvaraj RK; Renukaradhya GJ
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Liposomal nanoparticle-based conserved peptide influenza vaccine and monosodium urate crystal adjuvant elicit protective immune response in pigs

International Journal of Nanomedicine
2018-10 | Journal article
DOI: 10.2147/ijn.s178809
Part of ISSN: 1178-2013
Contributors: Santosh Dhakal; Xingguo Cheng; John Salcido; Sankar Renu; Kathy Bondra; Yashavanth Shaan Lakshmanappa; Christina Misch; Shristi Ghimire; Ninoshkaly Feliciano-Ruiz; Bradley Hogshead et al.
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search

Mucosal Immunity and Protective Efficacy of Intranasal Inactivated Influenza Vaccine Is Improved by Chitosan Nanoparticle Delivery in Pigs

Frontiers in Immunology
2018-05-02 | Journal article
DOI: 10.3389/fimmu.2018.00934
Part of ISSN: 1664-3224
Contributors: Santosh Dhakal; Sankar Renu; Shristi Ghimire; Yashavanth Shaan Lakshmanappa; Bradley T. Hogshead; Ninoshkaly Feliciano-Ruiz; Fangjia Lu; Harm HogenEsch; Steven Krakowka; Chang Won Lee et al.
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search

Intranasal delivery of influenza antigen by nanoparticles, but not NKT-cell adjuvant differentially induces the expression of B-cell activation factors in mice and swine.

Cellular immunology
2018-04 | Journal article
DOI: 10.1016/j.cellimm.2018.04.005
PMID: 29665972
Contributors: Renu S; Dhakal S; Kim E; Goodman J; Lakshmanappa YS; Wannemuehler MJ; Narasimhan B; Boyaka PN; Renukaradhya GJ
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Supplementation of inactivated influenza vaccine with norovirus P particle-M2e chimeric vaccine enhances protection against heterologous virus challenge in chickens.

PloS one
2017 | Journal article
DOI: 10.1371/journal.pone.0171174
PMID: 28151964
PMC: PMC5289506
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Biodegradable nanoparticle delivery of inactivated swine influenza virus vaccine provides heterologous cell-mediated immune response in pigs.

Journal of controlled release : official journal of the Controlled Release Society
2017-02 | Journal article
DOI: 10.1016/j.jconrel.2016.12.039
PMID: 28057521
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Polyanhydride nanovaccine against swine influenza virus in pigs.

Vaccine
2017-02 | Journal article
DOI: 10.1016/j.vaccine.2017.01.019
PMID: 28117173
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Entrapment of H1N1 Influenza Virus Derived Conserved Peptides in PLGA Nanoparticles Enhances T Cell Response and Vaccine Efficacy in Pigs.

PloS one
2016 | Journal article
DOI: 10.1371/journal.pone.0151922
PMID: 27093541
PMC: PMC4836704
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Inactivated porcine reproductive and respiratory syndrome virus vaccine adjuvanted with Montanide™ Gel 01 ST elicits virus-specific cross-protective inter-genotypic response in piglets.

Veterinary microbiology
2016-08 | Journal article
DOI: 10.1016/j.vetmic.2016.06.014
PMID: 27527768
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Comparative Advantage of Keyhole Right Flank Laparotomy and Ventral Midline Celiotomy for Ovariohysterectomy in Bitches

International Journal of Applied Sciences and Biotechnology
2016-06 | Journal article
DOI: 10.3126/ijasbt.v4i2.15098
Part of ISSN: 2091-2609
Contributors: Mohan Acharya; Manoj Kumar Sah; Dinesh Kumar Singh; Subir Singh; Santosh Dhakal
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search

Development of a porcine reproductive and respiratory syndrome virus-like-particle-based vaccine and evaluation of its immunogenicity in pigs.

Archives of virology
2016-06 | Journal article
DOI: 10.1007/s00705-016-2812-0
PMID: 27008569
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Adjuvant effects of invariant NKT cell ligand potentiates the innate and adaptive immunity to an inactivated H1N1 swine influenza virus vaccine in pigs.

Veterinary microbiology
2016-04 | Journal article
DOI: 10.1016/j.vetmic.2016.02.028
PMID: 27016770
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Mutations in a Highly Conserved Motif of nsp1β Protein Attenuate the Innate Immune Suppression Function of Porcine Reproductive and Respiratory Syndrome Virus.

Journal of virology
2016-04 | Journal article
DOI: 10.1128/jvi.03069-15
PMID: 26792733
PMC: PMC4794661
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central
grade
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Comparative analysis of routes of immunization of a live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in a heterologous virus challenge study.

Veterinary research
2016-03 | Journal article
DOI: 10.1186/s13567-016-0331-3
PMID: 26988085
PMC: PMC4797253
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Major Health Problems and Diseases of Street Dogs in Pokhara Valley, Nepal

International Journal of Applied Sciences and Biotechnology
2016-03 | Journal article
DOI: 10.3126/ijasbt.v4i1.14571
Part of ISSN: 2091-2609
Contributors: Mohan Acharya; Santosh Dhakal
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search

Evaluation of humoral immune status in porcine epidemic diarrhea virus (PEDV) infected sows under field conditions.

Veterinary research
2015 | Journal article
DOI: 10.1186/s13567-015-0285-x
PMID: 26667229
PMC: PMC4699368
Source: Self-asserted source
Santosh Dhakal via Europe PubMed Central

Prevalence of Demodectic Mange in Canines of Kathmandu Valley having Skin Disorder and Its Associated Risk Factors

International Journal of Applied Sciences and Biotechnology
2015-09 | Journal article
DOI: 10.3126/ijasbt.v3i3.13218
Part of ISSN: 2091-2609
Contributors: Denusha Shrestha; Balaram Thapa; Gaurav Rawal; Santosh Dhakal; Bishwas Sharma
Source: Self-asserted source
Santosh Dhakal via Crossref Metadata Search
Items per page:
Page 1 of 2

Peer review (11 reviews for 7 publications/grants)

Review activity for American Heart Association (2)
Review activity for Animals. (1)
Review activity for International journal of molecular sciences. (1)
Review activity for PLOS pathogens : (2)
Review activity for Tropical medicine and infectious disease. (1)
Review activity for Vaccines. (3)
Review activity for Veterinary microbiology. (1)
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