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Biography

Dr. Eric D’Ortenzio (MD, MPH), is a medical epidemiologist, specialist in emerging infectious diseases. He is currently working at ANRS Maladies infectieuses émergentes (Inserm) in France as the head of the department of Strategy and Partnerships. He is member of the board of EDCTP association and scientific coordinator of AFROSCREEN, a capacity building project for genomic surveillance. He is also clinician consultant in tropical medicine at the outpatient clinic of Bichat hospital (AP-HP) in Paris.

Prior to joining ANRS Maladies infectieuses émergentes, Dr Eric D’Ortenzio served as physician for health centers in Central African Republic and French Guiana, as field coordinator for MSF-F in Ivory Coast and in Sudan, epidemiologist for Public Health France in Reunion Island, head of the epidemiology research unit for Institut Pasteur New-Caledonia and scientific director for Solthis NGO. He has also coordinated REACTIng-Inserm, a French consortium on research and actions targeting emerging infectious diseases.

He has 25 years’ experience in preparedness and emergency outbreak response, primary health care, tropical medicine, humanitarian assistance, epidemiological surveillance, clinical and epidemiological research, capacity building and partnerships in complex and limited resources settings.

He has been trained as a Medical Doctor (Aix-Marseille University) with a specialization in General Medicine and in Public Health. He holds a Master Research Degree in Epidemiology (Paris Sorbonne University). He authored/co-authored more than 110 articles in international scientific journals on emerging infectious diseases.

Activities

Employment (2)

INSERM: Paris, Île-de-France, FR

2015-01-01 to present | Head (REACTing=Reseach and Action targeting Emerging infectious diseases that became ANRS Maladies infectieuses émergentes - Strategy and Partnerships)
Employment
Source: Self-asserted source
Eric D'Ortenzio

Assistance Publique - Hôpitaux de Paris: Paris, Île-de-France, FR

2013 to present | Physician in Tropical Medecine (Outpatient clinic - Bichat Hospital)
Employment
Source: Self-asserted source
Eric D'Ortenzio

Works (50 of 100)

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Changement global et risque de maladies vectorielles ou zoonotiques émergentes en Europe

Médecine et Maladies Infectieuses Formation
2023-12 | Journal article
Contributors: Louis Bohard; Cyrille Gourjault; Eric d'Ortenzio; Serge Morand; Catherine Chirouze
Source: check_circle
Crossref

Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in infants: a phase 2, randomised, double-blind, active-controlled trial in Guinea and Sierra Leone

The Lancet Global Health
2023-11 | Journal article
Part of ISSN: 2214-109X
Contributors: Edward Man-Lik Choi; Boris Lacarra; Muhammed O Afolabi; Boni Maxime Ale; Frank Baiden; Christine Bétard; Julie Foster; Benjamin Hamzé; Christine Schwimmer; Daniela Manno et al.
Source: Self-asserted source
Eric D'Ortenzio

Immunogenicity and vaccine shedding after 1 or 2 doses of rVZVΔG-ZEBOV-GP Ebola vaccine (ERVEBO®): Results from a phase 2, randomized, placebo-controlled trial in children and adults

Clinical Infectious Diseases
2023-11-15 | Journal article
Part of ISSN: 1058-4838
Part of ISSN: 1537-6591
Contributors: Andrew W Lee; Ken Liu; Edouard Lhomme; Julie Blie; John McCullough; Matthew T Onorato; Laurie Connor; Jakub Simon; Sheri Dubey; Susan VanRheenen et al.
Source: Self-asserted source
Eric D'Ortenzio

Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19

Kidney International Reports
2023-08 | Journal article
Part of ISSN: 2468-0249
Contributors: Marina Wainstein; Nicholas Spyrison; Danyang Dai; Moji Ghadimi; Jonathan S. Chávez-Iñiguez; Lilia Rizo-Topete; Barbara Wanjiru Citarella; Laura Merson; Jason D. Pole; Rolando Claure-Del Granado et al.
Source: Self-asserted source
Eric D'Ortenzio

Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry

Research and Practice in Thrombosis and Haemostasis
2023-07 | Journal article
Part of ISSN: 2475-0379
Contributors: Matthew J. Griffee; Patricia T. Bozza; Luis Felipe Reyes; Devin P. Eddington; Dorothea Rosenberger; Laura Merson; Barbara Wanjiru Citarella; Jonathon P. Fanning; Peta M.A. Alexander; John Fraser et al.
Source: Self-asserted source
Eric D'Ortenzio

Immune response of a two-dose heterologous Ebola vaccine regimen: summary of three African clinical trials using a single validated Filovirus Animal Nonclinical Group enzyme-linked immunosorbent assay in a single accredited laboratory

eBioMedicine
2023-05 | Journal article
Part of ISSN: 2352-3964
Contributors: Chelsea McLean; Houreratou BARRY; Mark Kieh; Zacchaeus Anywaine; Baimba Tapima Rogers; Seydou Doumbia; Sodiomon B. Sirima; Alimamy Serry-Bangura; Abdoul Habib Beavogui; Auguste Gaddah et al.
Source: Self-asserted source
Eric D'Ortenzio

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

Genome Medicine
2023-04-05 | Journal article
Part of ISSN: 1756-994X
Contributors: Daniela Matuozzo; Estelle Talouarn; Astrid Marchal; Peng Zhang; Jeremy Manry; Yoann Seeleuthner; Yu Zhang; Alexandre Bolze; Matthieu Chaldebas; Baptiste Milisavljevic et al.
Source: Self-asserted source
Eric D'Ortenzio

Characteristics and outcomes of an international cohort of 600 000 hospitalized patients with COVID-19

International Journal of Epidemiology
2023-02-28 | Journal article
Part of ISSN: 0300-5771
Part of ISSN: 1464-3685
Contributors: Christiana Kartsonaki; J Kenneth Baillie; Noelia García Barrio; Joaquín Baruch; Abigail Beane; OYEWALE TOMORI; Fernando Bozza; Tessa Broadley; Aidan Burrell; Gail Carson et al.
Source: Self-asserted source
Eric D'Ortenzio

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Scientific Data
2022-12 | Journal article
Part of ISSN: 2052-4463
Contributors: Eric D'Ortenzio; ISARIC Clinical Characterization Group; Ali Abbas; Sheryl Ann Abdukahil; Nurul Najmee Abdulkadir; Ryuzo Abe; Laurent Abel; Lara Absil; Kamal Abu Jabal; Hiba Abu Zayyad et al.
Source: Self-asserted source
Eric D'Ortenzio

Randomized Trial of Vaccines for Zaire Ebola Virus Disease

New England Journal of Medicine
2022-12-29 | Journal article
Part of ISSN: 0028-4793
Part of ISSN: 1533-4406
Contributors: PREVAC Study Team
Source: Self-asserted source
Eric D'Ortenzio

Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity

BMJ Paediatrics Open
2022-10 | Journal article
Part of ISSN: 2399-9772
Contributors: Eva Miranda Marwali; Aria Kekalih; Saptadi Yuliarto; Dyah Kanya Wati; Muhammad Rayhan; Ivy Cerelia Valerie; Hwa Jin Cho; Waasila Jassat; Lucille Blumberg; Maureen Masha et al.
Source: Self-asserted source
Eric D'Ortenzio

HIV stigma limits the effectiveness of PMTCT in Guinea: the ANRS 12344-DIAVINA study

Journal of Antimicrobial Chemotherapy
2022-10-28 | Journal article
Part of ISSN: 0305-7453
Part of ISSN: 1460-2091
Contributors: Eric D'Ortenzio; Guillaume Breton; Oumou Hawa Diallo; Mohamed Cissé; Oumou Hawa Diallo; Néné Aissatou Diallo; Sény Agnès Soumaoro; Yalikhatou Camara; Alice Montoyo; Christine Rouzioux et al.
Source: Self-asserted source
Eric D'Ortenzio

Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study

Critical Care
2022-09-13 | Journal article
Part of ISSN: 1364-8535
Contributors: Eric D'Ortenzio; Luis Felipe Reyes; Srinivas Murthy; Esteban Garcia-Gallo; Laura Merson; Elsa D. Ibáñez-Prada; Jordi Rello; Yuli V. Fuentes; Ignacio Martin-Loeches; Fernando Bozza et al.
Source: Self-asserted source
Eric D'Ortenzio
grade
Preferred source (of 2)‎

Health crisis: What opportunities for clinical drug research?

Therapies
2022-01 | Journal article
Part of ISSN: 0040-5957
Contributors: Eric D'Ortenzio; Dominique Deplanque; Stanislas Cviklinski; Marc Bardou; Florence Ader; Hervé Blanchard; Philippe Barthélémy; Isabelle David; Eric D’Ortenzio; Hélène Espérou et al.
Source: Self-asserted source
Eric D'Ortenzio

Sarilumab in adults hospitalised with moderate-to-severe COVID-19 pneumonia (CORIMUNO-SARI-1): An open-label randomised controlled trial

The Lancet Rheumatology
2022-01 | Journal article
Part of ISSN: 2665-9913
Contributors: Eric D'Ortenzio; Xavier Mariette; Olivier Hermine; Pierre-Louis Tharaux; Matthieu Resche-Rigon; Raphael Porcher; Philippe Ravaud; Serge Bureau; Maxime Dougados; Annick Tibi et al.
Source: Self-asserted source
Eric D'Ortenzio

Correction to: Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries

Trials
2021-12 | Journal article
Part of ISSN: 1745-6215
Contributors: Eric D'Ortenzio; Moses Badio; Edouard Lhomme; Mark Kieh; Abdoul Habib Beavogui; Stephen B. Kennedy; Seydou Doumbia; Bailah Leigh; Samba O. Sow; Alpha Diallo et al.
Source: Self-asserted source
Eric D'Ortenzio

The value of open-source clinical science in pandemic response: lessons from ISARIC

The Lancet Infectious Diseases
2021-12 | Journal article
Part of ISSN: 1473-3099
Contributors: Eric D'Ortenzio; Ali Abbas; Sheryl Ann Abdukahil; Nurul Najmee Abdulkadir; Ryuzo Abe; Laurent Abel; Lara Absil; Subhash Acharya; Andrew Acker; Shingo Adachi et al.
Source: Self-asserted source
Eric D'Ortenzio
grade
Preferred source (of 2)‎

Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort

eLife
2021-11-23 | Journal article
Part of ISSN: 2050-084X
Contributors: Eric D'Ortenzio; ISARIC Clinical Characterisation Group; Matthew Hall; Joaquín Baruch; Gail Carson; Barbara Wanjiru Citarella; Andrew Dagens; Emmanuelle A Dankwa; Christl A Donnelly; Jake Dunning et al.
Source: Self-asserted source
Eric D'Ortenzio

Sera Neutralizing Activities Against Severe Acute Respiratory Syndrome Coronavirus 2 and Multiple Variants 6 Months After Hospitalization for Coronavirus Disease 2019

Clinical Infectious Diseases
2021-09-15 | Journal article
Part of ISSN: 1058-4838
Part of ISSN: 1537-6591
Contributors: Maureen Betton; Marine Livrozet; Delphine Planas; Antoine Fayol; Blandine Monel; Benoit Védie; Timothée Bruel; Eric Tartour; Nicolas Robillard; Jean-Claude Manuguerra et al.
Source: Self-asserted source
Eric D'Ortenzio

Chronicles of a pandemic: How France coordinated the scientific research response to COVID-19

Infectious Diseases Now
2021-08 | Journal article
Part of ISSN: 2666-9919
Source: Self-asserted source
Eric D'Ortenzio

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Science Immunology
2021-08-19 | Journal article
Part of ISSN: 2470-9468
Source: Self-asserted source
Eric D'Ortenzio

Autoantibodies neutralizing type I IFNs are present in <b>~</b>4% of uninfected individuals over 70 years old and account for <b>~</b>20% of COVID-19 deaths.

Science immunology
2021-08-01 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Infection
2021-06-25 | Journal article
Part of ISSN: 0300-8126
Part of ISSN: 1439-0973
Source: Self-asserted source
Eric D'Ortenzio

Chronic use of renin‐angiotensin‐aldosterone system blockers and mortality in COVID‐19: A multicenter prospective cohort and literature review

Fundamental & Clinical Pharmacology
2021-05-16 | Journal article
Part of ISSN: 0767-3981
Part of ISSN: 1472-8206
Source: Self-asserted source
Eric D'Ortenzio

Bridging the gap between scientific discovery and clinical application during the COVID-19 epoch

Infectious Diseases Now
2021-03 | Journal article
Part of ISSN: 2666-9919
Source: Self-asserted source
Eric D'Ortenzio

Prevalence of Asymptomatic SARS-CoV-2 Infection

Annals of Internal Medicine
2021-02 | Journal article
Contributors: Muge Cevik; Isaac I. Bogoch; Gail Carson; Eric D’Ortenzio; Krutika Kuppalli
Source: check_circle
Crossref

Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries.

Trials
2021-01-23 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial.

The Lancet. Respiratory medicine
2021-01-22 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia: A Randomized Clinical Trial.

JAMA internal medicine
2021-01-01 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Rationale of a loading dose initiation for hydroxychloroquine treatment in COVID-19 infection in the DisCoVeRy trial-authors' response.

The Journal of antimicrobial chemotherapy
2021-01-01 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Detection of SARS-CoV-2 N-antigen in blood during acute COVID-19 provides a sensitive new marker and new testing alternatives.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
2020-12-08 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Corticosteroids in patients hospitalised for COVID-19 pneumonia who require oxygen: observational comparative study using routine care data.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
2020-12-07 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.

The New England journal of medicine
2020-12-02 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Impact on disease mortality of clinical, biological, and virological characteristics at hospital admission and overtime in COVID-19 patients.

Journal of medical virology
2020-11 | Journal article
Contributors: Yazdanpanah Y; French COVID cohort investigators and study group
Source: Self-asserted source
Eric D'Ortenzio via Europe PubMed Central

Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries

2020-09 | Preprint
Contributors: Badio M; Lhomme E; Kieh M; Beavogui AH; Kennedy SB; Doumbia S; Leigh B; Sow SO; Diallo A; Fusco D et al.
Source: Self-asserted source
Eric D'Ortenzio via Europe PubMed Central

Autoantibodies against type I IFNs in patients with life-threatening COVID-19.

Science (New York, N.Y.)
2020-09-24 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.

Science (New York, N.Y.)
2020-09-24 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adults.

BMJ open
2020-09-21 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Human plague: An old scourge that needs new answers.

PLoS neglected tropical diseases
2020-08-27 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Global outbreak research: harmony not hegemony.

The Lancet. Infectious diseases
2020-06-02 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study.

Lancet (London, England)
2020-02-20 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Can we make human plague history? A call to action.

BMJ global health
2019-11-10 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

New guidelines for the prevention of imported malaria in France.

Medecine et maladies infectieuses
2019-08-28 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Enrolling study personnel in Ebola vaccine trials: from guidelines to practice in a non-epidemic context.

Trials
2019-07-11 | Journal article
Source: Self-asserted source
Eric D'Ortenzio

Prevention of Ebola virus disease through vaccination: where we are in 2018.

Lancet (London, England)
2018-08 | Journal article
Contributors: Lévy Y; Lane C; Piot P; Beavogui AH; Kieh M; Leigh B; Doumbia S; D'Ortenzio E; Lévy-Marchal C; Pierson J et al.
Source: Self-asserted source
Eric D'Ortenzio via Europe PubMed Central

Plague: Bridging gaps towards better disease control.

Medecine et maladies infectieuses
2018-06 | Journal article
Contributors: D'Ortenzio E; Lemaître N; Brouat C; Loubet P; Sebbane F; Rajerison M; Baril L; Yazdanpanah Y
Source: Self-asserted source
Eric D'Ortenzio via Europe PubMed Central
grade
Preferred source (of 2)‎

Correction to: Imported falciparum malaria in adults: host- and parasite-related factors associated with severity. The French prospective multicenter PALUREA cohort study.

Intensive care medicine
2018-01 | Journal article
Contributors: Bruneel F; Tubach F; Mira JP; Houze S; Gibot S; Huisse MG; Megarbane B; Choquet C; Corne P; Peytel E et al.
Source: Self-asserted source
Eric D'Ortenzio via Europe PubMed Central

Vaccination and blood sampling acceptability during Ramadan fasting month: A cross-sectional study in Conakry, Guinea.

Vaccine
2017-05 | Journal article
Contributors: Peiffer-Smadja N; Ouedraogo R; D'Ortenzio E; Cissé PN; Zeggani Z; Beavogui AH; Faye SL; Le Marcis F; Yazdanpanah Y; Nguyen VK
Source: Self-asserted source
Eric D'Ortenzio via Europe PubMed Central

Jarisch-Herxheimer Reaction Among Patients with Leptospirosis: Incidence and Risk Factors.

The American Journal of Tropical Medicine and Hygiene
2017-01 | Journal article
Contributors: Guerrier G; Lefèvre P; Chouvin C; D'Ortenzio E
Source: Self-asserted source
Eric D'Ortenzio via Europe PubMed Central

Human IgG Antibody Response to Aedes Nterm-34kDa Salivary Peptide, an Epidemiological Tool to Assess Vector Control in Chikungunya and Dengue Transmission Area.

PLoS neglected tropical diseases
2016-12 | Journal article
Contributors: Elanga Ndille E; Doucoure S; Poinsignon A; Mouchet F; Cornelie S; D'Ortenzio E; DeHecq JS; Remoue F
Source: Self-asserted source
Eric D'Ortenzio via Europe PubMed Central
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