Bianca Brundel

Biography

Bianca Brundel received her PhD from the University Medical Center Groningen, the Netherlands and was trained in molecular and cellular biology (VU, Amsterdam) and clinical pharmacology (UMCG). Bianca is professor at the physiology department at the Amsterdam UMC, location VU University Medical Center. Her research is focused on the molecular mechanisms driving proteostasis derailment and pathophysiology of cardiac diseases, including atrial fibrillation and cardiomyopathies. Molecular findings are used to identify novel druggable targets. Her laboratory utilizes experimental cardiomyocyte and Drosophila cardiac disease models in combination with genetic and pharmacological manipulations. She is project leader of translational research projects and founder of the Atrial Fibrillation Innovation Platform (www.AFIPonline.org), to promote translational studies in collaboration with patients, and the Cardiac Arrhythmia Lab to develop bio-electrical diagnostic tools. As such, she contributed to forwarding candidate drugs into (pre-)clinical proof-of-principle studies.