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Extracellular vesicles, allergic airway inflammation, sensorineural hearing loss, stem cells
China

Activities

Employment (4)

The First Affiliated Hospital, Sun Yat-sen University: Guangzhou, Guangdong, CN

2025-01-01 to present | Associate Research Fellow, Attending doctor (Otorhinolaryngology Hospital)
Employment
Source: Self-asserted source
Shubin Fang

Sun Yat-sen University First Affiliated Hospital: Guangzhou, Guangdong, CN

2022-07-01 to 2023-12-31 | Associate research fellow, Resident doctor (Otorhinolaryngology Hospital)
Employment
Source: Self-asserted source
Shubin Fang

Sun Yat-sen University First Affiliated Hospital: Guangzhou, Guangdong, CN

2020-07-10 to 2022-06-30 | Postdoctoral fellow, Resident doctor (Otorhinolaryngology Hospital)
Employment
Source: Self-asserted source
Shubin Fang

Texas A and M University: College Station, TX, US

2017-03 to 2018-03 | Postdoctoral fellow (Molecular and Cellular Medicine)
Employment
Source: Self-asserted source
Shubin Fang

Education and qualifications (2)

Sun Yat-Sen University: Guangzhou, Guangdong, CN

2015-08 to 2020-06 | Ph.D (Otorhinolaryngology Hospital)
Education
Source: Self-asserted source
Shubin Fang

Southern Medical University: Guangzhou, Guangdong, CN

2010-09 to 2015-06 | MD Degree
Education
Source: Self-asserted source
Shubin Fang

Funding (7)

Regulatory Role and Mechanisms of Hsp70-Enriched Extracellular Vesicles from Stria Vascularis Endothelial Cells on Cochlear Macrophages in Noise-Induced Hearing Loss

2024-06 to 2027-05 | Grant
The First Affiliated Hospital of Sun Yat-sen University, Kelin Rising Star Talent Program (Guangzhou, Guangdong, CN)
Source: Self-asserted source
Shubin Fang

Immune regulation of serum amyloid A1 on macrophages with respiratory allergic inflammation and the mechanism

2024-01 to 2026-12 | Grant
Natural Science Foundation of Guangdong Province (Guangzhou, CN)
Source: Self-asserted source
Shubin Fang

Regulation of Hsp70 in endothelial vascular endothelial cells EVs in noise-induced deafness mice on inner ear hair cells and the mechanisms.

2024-01 to 2025-12 | Grant
Science Plan Fund of Guangzhou (Guangzhou, CN)
Source: Self-asserted source
Shubin Fang

Immunomodulatory Effects of Stem Cell-Derived Small Extracellular Vesicles on Respiratory Allergic Inflammation

2024-01 to 2024-12 | Grant
Sun Yat-sen University (Guangzhou, Guangdong, CN)
Source: Self-asserted source
Shubin Fang

Plasma extracellular vesicles in allergic rhinitis promote Th2 differentiation via miR-144-3p-mediated regulation of JAK1/3-STAT6 signaling pathway

2022-01 to 2024-12 | Grant
National Natural Science Foundation of China (Beijing, CN)
Source: Self-asserted source
Shubin Fang

The immunoregulatory effects of Der p 1-carrying plasma EVs on CD4+ T cells in allergic rhinitis

2021-05 to 2022-07 | Grant
China Postdoctoral Science Foundation (Beijing, CN)
Source: Self-asserted source
Shubin Fang

The antigen presenting chacrateristics of plasma EVs in allergic rhinitis patients and their immunoregulatory effects on CD4+T cells

2020-10 to 2023-09 | Grant
Basic and Applied Basic Research Foundation of Guangdong Province (Guangzhou, Guangdong, CN)
Source: Self-asserted source
Shubin Fang

Works (22)

Prediabetes and sleep patterns: Linking poor sleep to adverse outcomes through metabolic syndrome

Diabetes Research and Clinical Practice
2025-03 | Journal article
Part of ISSN: 0168-8227
Contributors: Zixuan Huang; Jie Deng; Hang Li; Shubin Fang; Yi Wei; Wenbin Lei; Weiping Wen; Lin Chen
Source: Self-asserted source
Shubin Fang

Characteristics and Prognosis of Patients With Non‐Syndromic Sensorineural Hearing Loss Associated With Myo15a Mutations

Otolaryngology–Head and Neck Surgery
2025-03-07 | Journal article
Part of ISSN: 0194-5998
Part of ISSN: 1097-6817
Contributors: Yueying Wang; Shubin Fang; Xiaoqing Cen; Yue Liang; Anhai Chen; Lusha Huang; Juan Wang; Guanxia Xiong; Kaitian Chen
Source: Self-asserted source
Shubin Fang

LDHA-mediated glycolysis in stria vascularis endothelial cells regulates macrophages function through CX3CL1-CX3CR1 pathway in noise-induced oxidative stress

Cell Death & Disease
2025-02-03 | Journal article | Author
Part of ISSN: 2041-4889
Contributors: Ying Yi; Min-Yu Wu; Kai-Tian Chen; An-Hai Chen; Lin-Qiu Li; Qin Xiong; Xian-Ren Wang; Lei Wenbin; Guan-Xia Xiong; Shubin Fang
Source: Self-asserted source
Shubin Fang

Plasma extracellular vesicles regulate the Functions of Th2 and ILC2 cells via miRNA-150-5p in patients with allergic rhinitis

International Immunopharmacology
2025-01 | Journal article
Part of ISSN: 1567-5769
Contributors: Shu-Bin Fang; Zhi-Rou Zhou; Qi Sun; Xiao-Qing Liu; Chan-Gu Li; Ying-Chun Xie; Bi-Xin He; Tian Tian; Xiao-Hui Deng; Qing-Ling Fu
Source: Self-asserted source
Shubin Fang

Extracellular Vesicle-Based Clinical Trials

Extracellular Vesicles
2024 | Book chapter
Part of ISBN: 9789819983643
Part of ISBN: 9789819983650
Contributors: Xingliang Fan; Shu-Bin Fang; Qing-Ling Fu
Source: Self-asserted source
Shubin Fang

Serum amyloid A1 induced dysfunction of airway macrophages via CD36 pathway in allergic airway inflammation

International Immunopharmacology
2024-12 | Journal article
Part of ISSN: 1567-5769
Contributors: Zhi-Rou Zhou; Shu-Bin Fang; Xiao-Qing Liu; Chan-Gu Li; Ying-Chun Xie; Bi-Xin He; Qi Sun; Tian Tian; Xiao-Hui Deng; Qing-Ling Fu
Source: Self-asserted source
Shubin Fang

Characterization of the components in plasma EVs unveiling the link between EVs-derived complement C3 with the severity and initial treatment response of profound sudden sensorineural hearing loss

International Immunopharmacology
2024-11 | Journal article
Part of ISSN: 1567-5769
Contributors: Hui-Ting Chen; Ying Yi; Wan-Yi Huang; Min-Yu Wu; Qin Xiong; Xian-Ren Wang; Min Liu; Xuan Wu; Guang-Li Jiang; Hui-Wen Zhuang et al.
Source: Self-asserted source
Shubin Fang

Endoscopic revision surgery for ossicular chain reconstruction: intraoperative findings and functional outcomes

European Archives of Oto-Rhino-Laryngology
2024-11-16 | Journal article
Part of ISSN: 0937-4477
Part of ISSN: 1434-4726
Contributors: Juan Wang; Yueying Wang; Shubin Fang; Lusha Huang; Xiaoqing Cen; Yue Liang; Anhai Chen; Wenbin Lei; Guanxia Xiong; Xuan Wu et al.
Source: Self-asserted source
Shubin Fang

Small extracellular vesicles derived from human mesenchymal stem cells prevent Th17-dominant neutrophilic airway inflammation via immunoregulation on Th17 cells

International Immunopharmacology
2024-05 | Journal article
Part of ISSN: 1567-5769
Contributors: Bi-Xin He; Shu-Bing Fang; Ying-Chun Xie; Dong-Xiao Lou; Zi-Cong Wu; Chan-Gu Li; Xiao-Qing Liu; Zhi-Rou Zhou; Long-Xin Huang; Tian Tian et al.
Source: Self-asserted source
Shubin Fang

Plasma EVs Display Antigen-Presenting Characteristics in Patients With Allergic Rhinitis and Promote Differentiation of Th2 Cells

Frontiers in Immunology
2021-10-08 | Journal article
Part of ISSN: 1664-3224
Source: Self-asserted source
Shubin Fang

Mesenchymal stem cell-derived exosomes improve motor function and attenuate neuropathology in a mouse model of Machado-Joseph disease

Stem Cell Research & Therapy
2020-12 | Journal article
Part of ISSN: 1757-6512
Source: Self-asserted source
Shubin Fang

Small extracellular vesicles derived from human mesenchymal stromal cells prevent group 2 innate lymphoid cell‐dominant allergic airway inflammation through delivery of miR‐146a‐5p

Journal of Extracellular Vesicles
2020-09 | Journal article
Part of ISSN: 2001-3078
Part of ISSN: 2001-3078
Source: Self-asserted source
Shubin Fang

Small extracellular vesicles derived from human MSCs prevent allergic airway inflammation via immunomodulation on pulmonary macrophages

Cell Death & Disease
2020-06 | Journal article
Part of ISSN: 2041-4889
Source: Self-asserted source
Shubin Fang

CysLT1R expression on ILC2s and effects of CysLT1R antagonist on ILC2 activity in patients with allergic rhinitis

Allergy
2020-04 | Journal article
Part of ISSN: 0105-4538
Part of ISSN: 1398-9995
Source: Self-asserted source
Shubin Fang

Effects of myeloid and plasmacytoid dendritic cells on ILC2s in patients with allergic rhinitis

Journal of Allergy and Clinical Immunology
2020-03 | Journal article
Part of ISSN: 0091-6749
Source: Self-asserted source
Shubin Fang

Human pluripotent stem cell-derived mesenchymal stem cells prevent chronic allergic airway inflammation via TGF-β1-Smad2/Smad3 signaling pathway in mice

Molecular Immunology
2019-05 | Journal article
Part of ISSN: 0161-5890
Source: Self-asserted source
Shubin Fang

Human iPSC-MSCs prevent steroid-resistant neutrophilic airway inflammation via modulating Th17 phenotypes

Stem Cell Research & Therapy
2018-12 | Journal article
Part of ISSN: 1757-6512
Source: Self-asserted source
Shubin Fang

Connexin 43-Mediated Mitochondrial Transfer of iPSC-MSCs Alleviates Asthma Inflammation

Stem Cell Reports
2018-11 | Journal article
Part of ISSN: 2213-6711
Source: Self-asserted source
Shubin Fang

MicroRNA-21 Mediates the Protective Effects of Mesenchymal Stem Cells Derived from iPSCs to Human Bronchial Epithelial Cell Injury Under Hypoxia

Cell Transplantation
2018-03 | Journal article
Part of ISSN: 0963-6897
Part of ISSN: 1555-3892
Source: Self-asserted source
Shubin Fang

The genes involved in asthma with the treatment of human embryonic stem cell-derived mesenchymal stem cells

Molecular Immunology
2018-03 | Journal article
Part of ISSN: 0161-5890
Source: Self-asserted source
Shubin Fang

Effects of mesenchymal stem cells from human induced pluripotent stem cells on differentiation, maturation, and function of dendritic cells

Stem Cell Research & Therapy
2017-12 | Journal article
Part of ISSN: 1757-6512
Source: Self-asserted source
Shubin Fang

Occupational and environmental risk factors for chronic rhinosinusitis in China: a multicentre cross-sectional study

Respiratory Research
2016-12 | Journal article
Part of ISSN: 1465-993X
Source: Self-asserted source
Shubin Fang

Peer review (1 review for 1 publication/grant)

Review activity for Stem cell research & therapy. (1)