Personal information

Emails & domains

Verified email addresses

Verified email domains

Countries

Malaysia

Activities

Collapse all

Employment (1)

IMU University: Kuala Lumpur, Kuala Lumpur, MY

2019-01-01 to present | Associate Professor (School of Pharmacy)
Employment
Source: Self-asserted source
Sook Yee Gan

Education and qualifications (1)

University of Malaya: Kuala Lumpur, Wilayah Persekutuan, MY

2002 to 2005 | Ph.D (Institute of Postgraduate Studies (IPS))
Education
Source: Self-asserted source
Sook Yee Gan

Funding (8)

A gene trap mutagenesis approach for the identification of NLRP1 inflammasome activation targets mediating beta amyloid (Aβ)-induced neuronal pyroptosis.

2016 to 2018 | Grant
Ministry of Higher Education, Malaysia (Kuala Lumpur, MY)
Source: Self-asserted source
Sook Yee Gan

Antidiabetic activity of catalpol on high fat diet/streptozotocin induced type-2 diabetes mice by improving insulin sensitivity and mitochondrial function. Granting Body

2016 to 2018 | Grant
Ministry of Higher Education, Malaysia (Kuala Lumpur, MY)
Source: Self-asserted source
Sook Yee Gan

Elucidation of mechanisms involved in the neuro protective properties of Padina species, a brown algae

2013 to 2015 | Grant
Ministry of Higher Education, Malaysia (Kuala Lumpur, MY)
GRANT_NUMBER:

FRGS/1/2013/ST03/IMU/02/1
Source: Self-asserted source
Sook Yee Gan

Biotechnological Applications of Selected Tropical and Temperate Seaweeds: Genetic Transformation of Chondrus, a commercial seaweed.

2012 to 2014 | Grant
MOSTI (Kuala Lumpur, MY)
Source: Self-asserted source
Sook Yee Gan

Potential Anti-Alzheimer’s activity of Brown algae metabolites.

2012 to 2014 | Grant
MOSTI (Kuala Lumpur, MY)
GRANT_NUMBER:

02-02-09-SF0017
Source: Self-asserted source
Sook Yee Gan

Expression Profiling of MicroRNA in Nasopharyngeal Carcinoma in Response to Interleukins and Transforming Growth Factor: Towards Unraveling the Roles of MicroRNA in Invasion and Metastasis

2010 to 2012 | Grant
Ministry of Higher Education, Malaysia (Kuala Lumpur, MY)
GRANT_NUMBER:

IMUR053_2010 (FRGS/1/10/ST/IMU/02/1)
Source: Self-asserted source
Sook Yee Gan

Production of an oral algal vaccine for WSSV in prawns

2008 to 2011 | Grant
MOSTI (Kuala Lumpur, MY)
GRANT_NUMBER:

TF0106B003

Source: Self-asserted source
Sook Yee Gan

Development of a genetic transformation system for Gracilaria.

2000 to 2008 | Grant
MOSTI (Kuala Lumpur, MY)
Source: Self-asserted source
Sook Yee Gan

Works (29)

Lipopolysaccharide (LPS) stimulation of Pancreatic Ductal Adenocarcinoma (PDAC) and macrophages activates the NLRP3 inflammasome that influences the levels of pro-inflammatory cytokines in a co-culture model

Cancer Biology and Therapy
2023 | Journal article
DOI: 10.1080/15384047.2023.2284857
EID:

2-s2.0-85178250733

Part of ISSN: 15558576 15384047
Contributors: Sivam, H.G.P.; Chin, B.Y.; Gan, S.Y.; Ng, J.H.; Gwenhure, A.; Chan, E.W.L.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

The Crosstalk between Pancreatic Ductal Adenocarcinoma (PDAC) and Macrophages in Tumour Microenvironments, and Its Effects on Inflammasome Activation and Pro- Inflammatory Cytokine Levels

Research Square
2022 | Other
DOI: 10.21203/rs.3.rs-1555189/v1
EID:

2-s2.0-85167248869
Contributors: Chan, W.L.E.; Paremes Sivam, H.G.; Chin, B.Y.; Gan, S.Y.; Ng, J.H.; Gwenhure, A.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Genes associated with amyloid-beta-induced inflammasome-mediated neuronal death identified using functional gene trap mutagenesis approach

International Journal of Biochemistry and Cell Biology
2021 | Journal article
DOI: 10.1016/j.biocel.2021.106014
EID:

2-s2.0-85106460593

Part of ISSN: 18785875 13572725
Contributors: Yap, J.K.Y.; Pickard, B.S.; Gan, S.Y.; Chan, E.W.L.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Piper sarmentosum roxb. Attenuates beta amyloid (aβ)-induced neurotoxicity via the inhibition of amyloidogenesis and tau hyperphosphorylation in sh-sy5y cells

Current Alzheimer Research
2021 | Journal article
DOI: 10.2174/1567205018666210324124239
EID:

2-s2.0-85104323870

Part of ISSN: 18755828 15672050
Contributors: Chan, E.W.L.; Yeo, E.T.Y.; Wong, K.W.L.; See, M.L.; Wong, K.Y.; Yap, J.K.Y.; Gan, S.Y.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Recent progress in genetically modified microalgae for enhanced carbon dioxide sequestration

Biomass and Bioenergy
2021 | Journal article
DOI: 10.1016/j.biombioe.2020.105927
EID:

2-s2.0-85097882042

Part of ISSN: 18732909 09619534
Contributors: Barati, B.; Zeng, K.; Baeyens, J.; Wang, S.; Addy, M.; Gan, S.-Y.; El-Fatah Abomohra, A.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Catalpol ameliorates insulin sensitivity and mitochondrial respiration in skeletal muscle of type-2 diabetic mice through insulin signaling pathway and ampk/sirt1/pgc-1α/ppar-γ activation

Biomolecules
2020 | Journal article
DOI: 10.3390/biom10101360
EID:

2-s2.0-85092033320

Part of ISSN: 2218273X
Contributors: Yap, K.H.; Yee, G.S.; Candasamy, M.; Tan, S.C.; Md, S.; Majeed, A.B.A.; Bhattamisra, S.K.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier
grade
Preferred source (of 2)‎

Functional Gene Trap Mutagenesis Screen for Genes and Molecular Mechanisms Underlying Amyloid-β-induced Inflammasome-mediated Neuronal Death

Research Square
2020 | Other
DOI: 10.21203/rs.3.rs-19699/v1
EID:

2-s2.0-85166714118
Contributors: Yap, J.K.Y.; Pickard, B.S.; Gan, S.Y.; Chan, E.W.L.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Self-reported perception of a dedicated research semester in pharmacy curriculum in enhancing research competencies

Asia Pacific Scholar
2020 | Journal article
DOI: 10.29060/TAPS.2020-5-3/OA2166
EID:

2-s2.0-85096380418

Part of ISSN: 24249270 24249335
Contributors: Tan, E.L.; Gan, S.Y.; Lim, W.M.; Pook, P.C.K.; Nadarajah, V.D.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Adenosine receptors as novel targets for the treatment of various cancers

Current Pharmaceutical Design
2019 | Journal article
DOI: 10.2174/1381612825666190716102037
EID:

2-s2.0-85074043980

Part of ISSN: 18734286 13816128
Contributors: Gorain, B.; Choudhury, H.; Yee, G.S.; Bhattamisra, S.K.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Fucosterol exerts protection against amyloid β-induced neurotoxicity, reduces intracellular levels of amyloid β and enhances the mRNA expression of neuroglobin in amyloid β-induced SH-SY5Y cells

International Journal of Biological Macromolecules
2019 | Journal article
DOI: 10.1016/j.ijbiomac.2018.10.021
EID:

2-s2.0-85054463082

Part of ISSN: 18790003 01418130
Contributors: Gan, S.Y.; Wong, L.Z.; Wong, J.W.; Tan, E.L.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Green algal molecular responses to temperature stress

Acta Physiologiae Plantarum
2019 | Journal article
DOI: 10.1007/s11738-019-2813-1
EID:

2-s2.0-85060864196

Part of ISSN: 01375881
Contributors: Barati, B.; Gan, S.-Y.; Lim, P.-E.; Beardall, J.; Phang, S.-M.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Piper sarmentosum Roxb. Root extracts confer neuroprotection by attenuating beta amyloid-induced pro-inflammatory cytokines released from microglial cells

Current Alzheimer Research
2019 | Journal article
DOI: 10.2174/1567205016666190228124630
EID:

2-s2.0-85064239115

Part of ISSN: 18755828 15672050
Contributors: Chan, E.W.L.; Yeo, E.T.Y.; Wong, K.W.L.; See, M.L.; Wong, K.Y.; Gan, S.Y.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

The NLRP3 inflammasome is involved in the neuroprotective mechanism of neural stem cells against microglia-mediated toxicity in SH-SY5Y cells via the attenuation of tau hyperphosphorylation and amyloidogenesis

NeuroToxicology
2019 | Journal article
DOI: 10.1016/j.neuro.2018.11.001
EID:

2-s2.0-85056710486

Part of ISSN: 18729711 0161813X
Contributors: Chan, E.W.L.; Krishnansamy, S.; Wong, C.; Gan, S.Y.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

The Role of Neuronal NLRP1 Inflammasome in Alzheimer’s Disease: Bringing Neurons into the Neuroinflammation Game

Molecular Neurobiology
2019 | Journal article
DOI: 10.1007/s12035-019-1638-7
EID:

2-s2.0-85066135891

Part of ISSN: 15591182 08937648
Contributors: Yap, J.K.Y.; Pickard, B.S.; Chan, E.W.L.; Gan, S.Y.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Agrobacterium-mediated gene delivery and transient expression in the red macroalga Chondrus crispus

Botanica Marina
2018 | Journal article
DOI: 10.1515/bot-2018-0028
EID:

2-s2.0-85053712183

Part of ISSN: 14374323 00068055
Contributors: Ramessur, A.D.; Bothwell, J.H.; Maggs, C.A.; Gan, S.Y.; Phang, S.M.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Effect of elevated temperature on the physiological responses of marine Chlorella strains from different latitudes

Journal of Applied Phycology
2018 | Conference paper
DOI: 10.1007/s10811-017-1198-z
EID:

2-s2.0-85021204628

Part of ISSN: 15735176 09218971
Contributors: Barati, B.; Lim, P.-E.; Gan, S.-Y.; Poong, S.-W.; Phang, S.-M.; Beardall, J.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Fucosterol inhibits the cholinesterase activities and reduces the release of pro-inflammatory mediators in lipopolysaccharide and amyloid-induced microglial cells

Journal of Applied Phycology
2018 | Journal article
DOI: 10.1007/s10811-018-1495-1
EID:

2-s2.0-85047356588

Part of ISSN: 15735176 09218971
Contributors: Wong, C.H.; Gan, S.Y.; Tan, S.C.; Gany, S.A.; Ying, T.; Gray, A.I.; Igoli, J.; Chan, E.W.L.; Phang, S.M.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Gene expression profile of marine Chlorella strains from different latitudes: stress and recovery under elevated temperatures

Journal of Applied Phycology
2018 | Journal article
DOI: 10.1007/s10811-018-1588-x
EID:

2-s2.0-85050666355

Part of ISSN: 15735176 09218971
Contributors: Barati, B.; Lim, P.-E.; Gan, S.-Y.; Poong, S.-W.; Phang, S.-M.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

In vitro neuroprotective effects of naringenin nanoemulsion against β-amyloid toxicity through the regulation of amyloidogenesis and tau phosphorylation

International Journal of Biological Macromolecules
2018 | Journal article
DOI: 10.1016/j.ijbiomac.2018.06.190
EID:

2-s2.0-85049475643

Part of ISSN: 18790003 01418130
Contributors: Md, S.; Gan, S.Y.; Haw, Y.H.; Ho, C.L.; Wong, S.; Choudhury, H.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Piper sarmentosum Roxb. confers neuroprotection on beta-amyloid (Aβ)-induced microglia-mediated neuroinflammation and attenuates tau hyperphosphorylation in SH-SY5Y cells

Journal of Ethnopharmacology
2018 | Journal article
DOI: 10.1016/j.jep.2018.02.025
EID:

2-s2.0-85042373639

Part of ISSN: 18727573 03788741
Contributors: Yeo, E.T.Y.; Wong, K.W.L.; See, M.L.; Wong, K.Y.; Gan, S.Y.; Chan, E.W.L.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Random mutagenesis and precise gene editing technologies: applications in algal crop improvement and functional genomics

European Journal of Phycology
2017 | Journal article
DOI: 10.1080/09670262.2017.1358827
EID:

2-s2.0-85031115901

Part of ISSN: 14694433 09670262
Contributors: Gan, S.Y.; Maggs, C.A.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Genetic and metabolic engineering of microalgae

Green Energy and Technology
2016 | Book chapter
DOI: 10.1007/978-3-319-12334-9_16
EID:

2-s2.0-85147002654

Part of ISSN: 18653537 18653529
Contributors: Gan, S.-Y.; Lim, P.-E.; Phang, S.-M.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

MicroRNAs serving as potential biomarkers and therapeutic targets in nasopharyngeal carcinoma: A critical review

Critical Reviews in Oncology/Hematology
2016 | Journal article
DOI: 10.1016/j.critrevonc.2016.04.006
EID:

2-s2.0-84969960008

Part of ISSN: 18790461 10408428
Contributors: Lee, K.T.W.; Tan, J.-K.; Lam, A.K.Y.; Gan, S.-Y.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Elucidating the roles of miR-372 in cell proliferation and apoptosis of nasopharyngeal carcinoma TW01 cells

Experimental Oncology
2014 | Journal article
EID:

2-s2.0-84907551794

Part of ISSN: 18129269
Contributors: Tan, J.-K.; Tan, E.-L.; Gan, S.-Y.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Effects of IL-6, IL-10 and TGF-β on the expression of survivin and apoptosis in nasopharyngeal carcinoma TW01 cells

Experimental Oncology
2012 | Journal article
EID:

2-s2.0-84865959960

Part of ISSN: 18129269
Contributors: Poh, Y.W.; Gan, S.Y.; Tan, E.L.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Interleukins, laminin and epstein - barr virus latent membrane protein 1 (EBV LMP1) Promote metastatic phenotype in nasopharyngeal carcinoma

BMC Cancer
2010 | Journal article
DOI: 10.1186/1471-2407-10-574
EID:

2-s2.0-77958030259

Part of ISSN: 14712407
Contributors: Chew, M.M.S.; Gan, S.; Khoo, A.S.B.; Tan, E.-L.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Identification of random amplified polymorphic DNA (RAPD) marker for differentiating male from female and sporophytic thalli of Gracilaria changii (Rhodophyta)

Journal of Applied Phycology
2007 | Conference paper
DOI: 10.1007/s10811-007-9224-1
EID:

2-s2.0-36448935674

Part of ISSN: 09218971
Contributors: Sim, M.C.; Lim, P.E.; Gan, S.Y.; Phang, S.M.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Morphological and molecular characterisation and differentiation of Sargassum baccularia and S. polycystum (Phaeophyta)

Journal of Applied Phycology
2004 | Conference paper
DOI: 10.1007/s10811-004-5504-1
EID:

2-s2.0-22844443983

Part of ISSN: 09218971
Contributors: Wong, C.-L.; Gan, S.-Y.; Phang, S.-M.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier

Transient expression of lacZ in particle bombarded Gracilaria changii (Gracilariales, Rhodophyta)

Journal of Applied Phycology
2003 | Journal article
DOI: 10.1023/A:1025170010916
EID:

2-s2.0-0042761745

Part of ISSN: 09218971
Contributors: Gan, S.-Y.; Qin, S.; Othman, R.Y.; Yu, D.; Phang, S.-M.
Source: Self-asserted source
Sook Yee Gan via Scopus - Elsevier
How many people are using ORCID?