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Design, synthesis, characterization, structure-activity relationship, and molecular docking studies of novel 2,3-dihydropyrimidin-4(5H)-one and pyrimido[5,4–c] pyridazine-4-carbonitrile derivatives with biological evaluation

Journal of Molecular Structure
2024-12 | Journal article
Contributors: Mohamed A.M. Abdel Reheim; Basma Ghazal; Ibrahim S. Abdel Hafiz; HendS. Abdel Rady; Gameel A.M. Elhagalic; Mohamed S.A. El-Gaby
Source: check_circle
Crossref

Fluorinated Sulfonamides: Synthesis, Characterization, In Silico, Molecular Docking, ADME, DFT Predictions, and Structure‐Activity Relationships, as Well as Assessments of Antimicrobial and Antioxidant Activities

Drug Development Research
2024-12 | Journal article
Contributors: Mohamed A. M. Abdel Reheim; Basma Ghazal; Sayeda Abdelrazek Abdelhamid; Gameel A. M. Elhagali; Mohamed S. A. El‐Gaby
Source: check_circle
Crossref

Advanced Pyrene Copolymer/rGO Hydrogels for Efficient Congo Red Removal from Aqueous Systems

ChemistrySelect
2024-05-13 | Journal article
Contributors: Soleen S. Ahmed; Aula A. Alwattar; Shireen O. Ismael; Elsayed Zaki; Modather Hussein; Alexander J. Casson; Peter Quayle; Athir M. Haddad
Source: check_circle
Crossref

A new class of anti-proliferative activity and apoptotic inducer with molecular docking studies for a novel of 1,3-dithiolo[4,5-b]quinoxaline derivatives hybrid with a sulfonamide moiety

RSC Advances
2023 | Journal article
Contributors: Mostafa A. Ismail; Moustafa S. Abusaif; Mohamed S. A. El-Gaby; Yousry A. Ammar; Ahmed Ragab
Source: check_circle
Crossref

Corrosion inhibition of mild steel in 1 M HCl by pyrazolone-sulfonamide hybrids: synthesis, characterization, and evaluation

Scientific Reports
2023-10-29 | Journal article
Contributors: Ashraf M. Ashmawy; M. A. Mostafa; Abo-Bakr Kamal; Gomaa A. M. Ali; M. S. A. El-Gaby
Source: check_circle
Crossref

Corrosion inhibition behavior of the synthesized pyrazoline-sulfonamide hybrid of mild steel in aqueous solutions: experimental and quantum investigations

Journal of Chemical Sciences
2022-08-25 | Journal article
Contributors: Abo-Bakr Kamal; M A Mostfa; Ashraf M Ashmawy; M S A El-Gaby; Gomaa A M Ali
Source: check_circle
Crossref

Synthesis and in vivo evaluation of novel benzimidazole‐sulfonamide hybrids and Lucilia cuprina maggots' excretion/secretion topical gels for wound healing

Journal of the Chinese Chemical Society
2021-07 | Journal article
Contributors: Asmaa M. Sayed; Nashwa M. Saleh; Mohamed S. A. El‐Gaby; Mohammad R. K. Abdel‐Samad; Fatma A. Taher
Source: check_circle
Crossref

Design, synthesis, molecular docking, in silico ADMET profile and anticancer evaluations of sulfonamide endowed with hydrazone-coupled derivatives as VEGFR-2 inhibitors

Bioorganic Chemistry
2021-03 | Journal article
Part of ISSN: 0045-2068
Source: Self-asserted source
Mohamed El-Gaby

New modified poly(ester amide) resins and their uses as a binder for surface coating with different applications

Pigment & Resin Technology
2021-03-11 | Journal article
Part of ISSN: 0369-9420
Part of ISSN: 0369-9420
Source: Self-asserted source
Mohamed El-Gaby

Design, green synthesis, molecular docking and anticancer evaluations of diazepam bearing sulfonamide moieties as VEGFR-2 inhibitors

Bioorganic Chemistry
2020-11 | Journal article
Part of ISSN: 0045-2068
Source: Self-asserted source
Mohamed El-Gaby

Sulfonamides: Synthesis and the recent applications in Medicinal Chemistry

Egyptian Journal of Chemistry
2020-08-12 | Journal article
Part of ISSN: 2357-0245
Source: Self-asserted source
Mohamed El-Gaby

First example of Azo-Sulfa conjugated chromene moieties: Synthesis, characterization, antimicrobial assessment, docking simulation as potent class I histone deacetylase inhibitors and antitumor agents

Bioorganic Chemistry
2019 | Journal article
EID:

2-s2.0-85071991140

Contributors: Okasha, R.M.; Alsehli, M.; Ihmaid, S.; Althagfan, S.S.; El-Gaby, M.S.A.; Ahmed, H.E.A.; Afifi, T.H.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Regioselective transmonocyanoacetylation of o-phenylenediamine derivatives: simple and efficient synthesis of 2-cyanomethylbenzimidazole derivatives

Journal of the Iranian Chemical Society
2019 | Journal article
EID:

2-s2.0-85061348425

Contributors: Ammar, Y.A.; Abbas, S.Y.; Fouad, S.A.; Salem, M.A.; El-gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

An overview on synthetic strategies to coumarins

Synthetic Communications
2018 | Journal article
EID:

2-s2.0-85048283554

Contributors: Salem, M.A.; Helal, M.H.; Gouda, M.A.; Ammar, Y.A.; El-Gaby, M.S.A.; Abbas, S.Y.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

New sulfonamide hybrids: Synthesis, in vitro antimicrobial activity and docking study of some novel sulfonamide derivatives bearing carbamate/acyl-thiourea scaffolds

Mediterranean Journal of Chemistry
2018 | Journal article
EID:

2-s2.0-85058678098

Contributors: El-Gaby, M.S.A.; Hussein, M.F.; Hassan, M.I.; Ali, A.M.; Elshaier, Y.A.M.M.; Gebril, A.S.; Faraghally, F.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Overview on the synthetic routes to nicotine nitriles

Synthetic Communications
2018 | Journal article
EID:

2-s2.0-85040982645

Contributors: Salem, M.A.; Helel, M.H.; Gouda, M.A.; Ammar, Y.A.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Synthesis, characterization and in vitro biological screening of 4-hydroxy naphthalen-1-yl, naphtho[1,2-b]furan, benzo[h]chromene and 5,6-dihydropyridazine derivatives containing sulfonamide moiety

Mediterranean Journal of Chemistry
2018 | Journal article
EID:

2-s2.0-85058696484

Contributors: El-Gaby, M.S.A.; Hassan, M.I.; Hussein, M.F.; Ali, A.M.; Abdelmoaz, M.A.; Elaasser, M.M.; Faraghally, F.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Synthesis, structural characterization and anticancer evaluation of pyrazole derivatives

Medicinal Chemistry Research
2018 | Journal article
EID:

2-s2.0-85028874513

Contributors: El-Gaby, M.S.A.; Ghorab, M.M.; Ismail, Z.H.; Abdel-Gawad, S.M.; Aly, H.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

β-Oxo anilides in Heterocyclic Synthesis: Novel synthesis of polyfunctionally pyridines, pyrimidines and benzothiazole derivatives

Egyptian Journal of Chemistry
2018 | Journal article
EID:

2-s2.0-85060111510

Contributors: Hussein, A.M.; El-Gaby, M.S.A.; Abu-Shenab, F.A.; Abdel-Raheim, M.A.M.; El-Apasery, M.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Β-Oxo anilides in heterocyclic synthesis: Novel synthesis of pyridazinones, pyrazolopyridazines and cinnolines

Egyptian Journal of Chemistry
2018 | Journal article
EID:

2-s2.0-85060079675

Contributors: Hussein, A.M.; El-Gaby, M.S.A.; Abu-Shenab, F.A.; Abdel-Raheim, M.A.M.; El-Apasery, M.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Antimicrobial and anticancer activity of some novel fluorinated thiourea derivatives carrying sulfonamide moieties: Synthesis, biological evaluation and molecular docking

Chemistry Central Journal
2017 | Journal article
EID:

2-s2.0-85018519916

Contributors: Ghorab, M.M.; Alsaid, M.S.; El-Gaby, M.S.A.; Elaasser, M.M.; Nissan, Y.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Chemistry of 2-cyanomethylene-4-thiazolidinone

Journal of Sulfur Chemistry
2017 | Journal article
EID:

2-s2.0-85018297424

Contributors: El-Gaby, M.S.A.; Ammar, Y.A.; El-Hag Ali, G.A.M.; Helal, M.H.M.; Salem, M.A.; Ghorab, M.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Diphenic acid derivatives: Synthesis, reactions, and applications

Synthetic Communications
2017 | Journal article
EID:

2-s2.0-85016475138

Contributors: Salem, M.A.; Helel, M.H.; Ammar, Y.A.; El-Gaby, M.S.A.; Thabet, H.K.; Gouda, M.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Naproxen derivatives: Synthesis, reactions, and biological applications

Synthetic Communications
2017 | Journal article
EID:

2-s2.0-85020555202

Contributors: Ammar, Y.A.; Salem, M.A.; Fayed, E.A.; Helal, M.H.; El-Gaby, M.S.A.; Thabet, H.K.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Novel thiourea derivatives bearing sulfonamide moiety as anticancer agents through COX-2 inhibition

Anti-Cancer Agents in Medicinal Chemistry
2017 | Journal article
EID:

2-s2.0-85031695254

Contributors: Ghorab, M.M.; El-Gaby, M.S.A.; Alsaid, M.S.; Elshaier, Y.A.M.M.; Soliman, A.M.; El-Senduny, F.F.; Badria, F.A.; Sherif, A.Y.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Synthesis, docking study and biological evaluation of some new thiourea derivatives bearing benzenesulfonamide moiety

Chemistry Central Journal
2017 | Journal article
EID:

2-s2.0-85019391586

Contributors: Ghorab, M.M.; El-Gaby, M.S.A.; Soliman, A.M.; Alsaid, M.S.; Abdel-Aziz, M.M.; Elaasser, M.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Biological evaluation of some new N-(2,6-dimethoxypyrimidinyl) thioureido benzenesulfonamide derivatives as potential antimicrobial and anticancer agents

European Journal of Medicinal Chemistry
2016 | Journal article
EID:

2-s2.0-84984701146

Contributors: Ghorab, M.M.; Alsaid, M.S.; El-Gaby, M.S.A.; Safwat, N.A.; Elaasser, M.M.; Soliman, A.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Design, synthesis and anticancer activity of new 3-cyano-2 (1H)-pyridone and 3-cyanopyridine-2-(1H)-thione derivatives

Oriental Journal of Chemistry
2015 | Journal article
EID:

2-s2.0-84944456781

Contributors: Motaal, E.A.A.; El-Gaby, M.S.A.; Salem, M.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Synthesis and spectroscopic characterization of novel 2-amino-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidine and pyrimido[1,2-a]pyrimidine derivatives

Chinese Chemical Letters
2015 | Journal article
EID:

2-s2.0-84937425345

Contributors: El-Gaby, M.S.A.; Micky, J.A.; Saleh, N.M.; Ammar, Y.A.; Mohamed, H.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Cyanoacetanilides intermediates in heterocyclic synthesis. Part 6: Preparation of some hitherto unknown 2-oxopyridine, bipyridine, isoquinoline and chromeno[3,4-c]pyridine containing sulfonamide moiety

Arabian Journal of Chemistry
2014 | Journal article
EID:

2-s2.0-84908229247

Contributors: Ammar, Y.A.; El-Gaby, M.S.A.; Salem, M.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Cyanoacetanilide intermediates in heterocyclic synthesis. Part 7: Preparation of some spiro[indoline-3,4′-pyridine] and chromeno[3,4-c] pyridine derivatives

Heterocyclic Communications
2013 | Journal article
EID:

2-s2.0-84881653717

Contributors: Ammar, Y.A.; Ali, M.M.; Mohamed, Y.A.; Thabet, H.K.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Synthesis and biological evaluation of some novel thiazole compounds as potential anti-inflammatory agents

European Journal of Medicinal Chemistry
2013 | Journal article
EID:

2-s2.0-84879199678

Contributors: Helal, M.H.M.; Salem, M.A.; El-Gaby, M.S.A.; Aljahdali, M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Facile and convenient synthesis of pyrimidine, 4H-3,1-benzoxazin-4-one, pyrazolo[5,1-b]quinazoline, pyrido[1,2-a]quinazoline, and chromeno[3′, 4′:4,5]pyrido[1,2-a]quinazoline derivatives

Turkish Journal of Chemistry
2011 | Journal article
EID:

2-s2.0-81255191552

Contributors: Ammar, Y.A.; Bondock, S.; Al-Sehemi, A.G.; El-Gaby, M.S.A.; Fouda, A.M.; Thabet, H.Kh.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Some cyclization reactions with 2-ethoxycarbonylmethylidene-4,5-dihydro-4- thiazolinone

Phosphorus, Sulfur and Silicon and the Related Elements
2010 | Journal article
EID:

2-s2.0-77954378918

Contributors: Ammar, Y.A.; Mohamed, Y.A.; El-Hagali, G.A.M.; Abd El-Aal, A.S.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Chemistry of 2,3-dichloroquinoxalines

Phosphorus, Sulfur and Silicon and the Related Elements
2009 | Journal article
EID:

2-s2.0-61449196826

Contributors: Ammar, Y.A.; Al-Sehemi, A.G.; El-Sharief, A.M.Sh.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Cyanoacetanilides intermediates in heterocyclic synthesis. Part 5: Preparation of hitherto unknown 5-aminopyrazole and pyrazolo[1,5-a]pyrimidine derivatives containing sulfamoyl moiety

Journal of the Chinese Chemical Society
2009 | Journal article
EID:

2-s2.0-77952336702

Contributors: Ammar, Y.A.; Aly, M.M.; Al-Sehemi, A.A.G.; Salem, M.A.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Novel antitumor acetamide, pyrrole, pyrrolopyrimidine, thiocyanate, hydrazone, pyrazole, isothiocyanate and thiophene derivatives containing a biologically active pyrazole moiety

Arzneimittel-Forschung/Drug Research
2009 | Journal article
EID:

2-s2.0-74249096851

Contributors: Alqasoumi, S.I.; Ghorab, M.M.; Ismail, Z.H.; Abdel-Gawad, S.M.; El-Gaby, M.S.A.; Aly, H.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Synthesis of thiazolidine and thiophene derivatives for evaluation as anticancer agents

Phosphorus, Sulfur and Silicon and the Related Elements
2009 | Journal article
EID:

2-s2.0-74849120957

Contributors: El-Gaby, M.S.A.; Ismail, Z.H.; Abdel-Gawad, S.M.; Aly, H.M.; Ghorab, M.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4′-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones

European Journal of Medicinal Chemistry
2009 | Journal article
EID:

2-s2.0-67651147952

Contributors: El-Gaby, M.S.A.; El-Hag Ali, G.A.M.; El-Maghraby, A.A.; Abd El-Rahman, M.T.; Helal, M.H.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

β-Oxo anilides in heterocyclic synthesis: Synthesis of tri- and tetracyclic heteroaromatic containing a bridgehead nitrogen atom

Organic Communications
2009 | Journal article
EID:

2-s2.0-79952583533

Contributors: Hussein, A.H.M.; El-Gaby, M.S.; Abu-Shanab, F.; Abdel-Raheim, M.A.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Antitumor activity of some novel 1,2,5-thiadiazole derivatives

Phosphorus, Sulfur and Silicon and the Related Elements
2008 | Journal article
EID:

2-s2.0-52949135955

Contributors: Ismail, Z.H.; Ghorab, M.M.; Mohamed, E.M.A.; Aly, H.M.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Cyanoacetanilides intermediates in heterocyclic synthesis. Part 4: Preparation of some hitherto unknown thiazolidine and bisthiazolidine derivatives

Phosphorus, Sulfur and Silicon and the Related Elements
2008 | Journal article
EID:

2-s2.0-46249086196

Contributors: Ammar, Y.A.; Aly, M.M.; Al-Sehemi, A.G.; Mohamed, Y.A.; Salem, M.A.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Dapson in heterocyclic chemistry, part III: Synthesis, antimicrobial, and antitumor activities of some new bisheterocyclic compounds containing biologically active diphenylsulfone moiety

Phosphorus, Sulfur and Silicon and the Related Elements
2008 | Journal article
EID:

2-s2.0-55549131159

Contributors: Ghorab, M.M.; Amin, N.E.; El Gaby, M.S.A.; Taha, N.M.H.; Shehab, M.A.; Faker, I.M.I.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Dapson in heterocyclic chemistry, part IV: Synthesis of some novel diphenylsulfones containing acetamide, pyrrolidine, piperazine, and thiomorpholine moieties as antimicrobial and antitumor agents

Phosphorus, Sulfur and Silicon and the Related Elements
2008 | Journal article
EID:

2-s2.0-55549086163

Contributors: Ghorab, M.M.; El Gaby, M.S.A.; Amin, N.E.; Taha, N.M.H.; Shehab, M.A.; Faker, I.M.I.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Novel synthesis of pyrano[2,3-d]thiazole, thiazolo[3,2-a]pyridine, and pyrazolo [3′,4′:4,5] thiazolo[3,2-a]pyridine derivatives

Phosphorus, Sulfur and Silicon and the Related Elements
2008 | Journal article
EID:

2-s2.0-55549109749

Contributors: El-Hag Ali, G.A.M.; Abd El-Rahman, M.T.; Helal, M.H.M.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Synthesis of some novel benzothiazole derivatives

Phosphorus, Sulfur and Silicon and the Related Elements
2008 | Journal article
EID:

2-s2.0-46249105974

Contributors: Hussein, A.M.; Abu-Shanab, F.A.; Abdel Raheim, M.A.M.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Recent trends in chemistry of thiazolopyridines

Phosphorus, Sulfur and Silicon and the Related Elements
2006 | Journal article
EID:

2-s2.0-32944474420

Contributors: El-Gaby, M.S.A.; Al-Sehemi, A.G.; Mohamed, Y.A.; Ammar, Y.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Synthesis and biological activity of some novel thieno[2,3-b]quinoline, quinolino[3′,2′-4,5] thieno[3,2-d]pyrimidine and pyrido[2′,3′:4,5] thieno[2,3-b]quinoline derivatives

Phosphorus, Sulfur and Silicon and the Related Elements
2006 | Journal article
EID:

2-s2.0-30344447512

Contributors: El-Gaby, M.S.A.; Abdel-Gawad, S.M.; Ghorab, M.M.; Heiba, H.I.; Aly, H.M.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

The syntheses of new cyclopenta[d][1,3]thiazine derivatives and their use as antimicrobial agents

Phosphorus, Sulfur and Silicon and the Related Elements
2006 | Journal article
EID:

2-s2.0-33745113231

Contributors: El-Gaby, M.S.A.; Saleh, N.M.; Micky, J.A.; Ammar, Y.A.; Mohamed, H.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier

Cyanoacetanilides intermediates in heterocyclic synthesis, part 3: Novel syntheses of thiazolinone and thiazolo[3,2-a]pyridine derivatives

Phosphorus, Sulfur and Silicon and the Related Elements
2005 | Journal article
EID:

2-s2.0-31744443262

Contributors: Ammar, Y.A.; El-Sharief, A.M.Sh.; Al-Sehemi, A.G.; Mohamed, Y.A.; El-Hag Ali, G.A.M.; Senussi, M.A.; El-Gaby, M.S.A.
Source: Self-asserted source
Mohamed El-Gaby via Scopus - Elsevier
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