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Employment (3)

Tsinghua University: Beijing, Beijing, CN

2013-09 to present | Principal Investigator (School of Life Sciences)
Employment
Source: Self-asserted source
Jun Yao

Salk Institute for Biological Studies: La Jolla, CA, US

2011-10 to 2013-09 | Research Associate (Laboratory of Genetics)
Employment
Source: Self-asserted source
Jun Yao

HHMI, University of Wisconsin Madison: Madison, WI, US

2007-09 to 2011-09 | Postdoctoral Research Associate (Department of Neuroscience)
Employment
Source: Self-asserted source
Jun Yao

Education and qualifications (1)

Pennsylvania State University: University Park, PA, US

2002-08 to 2007-08 | PhD (Department of Biology)
Education
Source: Self-asserted source
Jun Yao

Works (25)

Single-molecule two- and three-colour FRET studies reveal a transition state in SNARE disassembly by NSF

Nature Communications
2025-01-02 | Journal article
DOI: 10.1038/s41467-024-55531-0
Contributors: Sudheer K. Cheppali; Chang Li; Wenjing Xing; Ruirui Sun; Mengyi Yang; Yi Xue; Si-Yao Lu; Jun Yao; Shan Sun; Chunlai Chen et al.
Source: check_circle
Crossref

Zika virus NS5 protein inhibits type I interferon signaling via CRL3 E3 ubiquitin ligase-mediated degradation of STAT2

Proceedings of the National Academy of Sciences
2024-08-20 | Journal article
DOI: 10.1073/pnas.2403235121
Contributors: Wenlin Ren; Chonglei Fu; Yu Zhang; Xiaohui Ju; Xi Jiang; Jingwei Song; Mingli Gong; Zhuoyang Li; Wenchun Fan; Jun Yao et al.
Source: check_circle
Crossref

Synaptotagmin-7–mediated activation of spontaneous NMDAR currents is disrupted in bipolar disorder susceptibility variants

PLOS Biology
2021-07-06 | Journal article
DOI: 10.1371/journal.pbio.3001323
Part of ISSN: 1545-7885
Source: Self-asserted source
Jun Yao
grade
Preferred source (of 2)‎

miR-218-2 regulates cognitive functions in the hippocampus through complement component 3–dependent modulation of synaptic vesicle release

Proceedings of the National Academy of Sciences
2021-04-06 | Journal article
DOI: 10.1073/pnas.2021770118
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Jun Yao

Synaptotagmin-1 interacts with PI(4,5)P2 to initiate synaptic vesicle docking in hippocampal neurons

Cell Reports
2021-03 | Journal article
DOI: 10.1016/j.celrep.2021.108842
Part of ISSN: 2211-1247
Source: Self-asserted source
Jun Yao

Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity

Proceedings of the National Academy of Sciences
2020-12-08 | Journal article
DOI: 10.1073/pnas.2016416117
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Jun Yao

Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice

Proceedings of the National Academy of Sciences
2020-02-25 | Journal article
DOI: 10.1073/pnas.1918165117
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Jun Yao

Mechanistic insights into the SNARE complex disassembly

Science Advances
2019-04-05 | Journal article
DOI: 10.1126/sciadv.aau8164
Contributors: Xuan Huang; Shan Sun; Xiaojing Wang; Fenghui Fan; Qiang Zhou; Shan Lu; Yong Cao; Qiu-Wen Wang; Meng-Qiu Dong; Jun Yao et al.
Source: check_circle
Crossref

CRISPR interference-based specific and efficient gene inactivation in the brain

Nature Neuroscience
2018-02-05 | Journal article
DOI: 10.1038/s41593-018-0077-5
Part of ISSN: 1097-6256
Contributors: Yi Zheng; Wei Shen; Jian Zhang; Bo Yang; Yao-Nan Liu; Huihui Qi; Xia Yu; Si-Yao Lu; Yun Chen; Yu-Zhou Xu et al.
Source: Self-asserted source
Jun Yao via Crossref Metadata Search

Application of induced pluripotent stem cells to understand neurobiological basis of bipolar disorder and schizophrenia

Psychiatry and Clinical Neurosciences
2017-09 | Journal article
DOI: 10.1111/pcn.12528
Contributors: Yao‐Nan Liu; Si‐Yao Lu; Jun Yao
Source: check_circle
Crossref

Distinct roles of NMDA receptors at different stages of granule cell development in the adult brain.

2015 | Journal article
DOI: 10.7554/elife.07871
PMID: 26473971
PMC: PMC4608052
Contributors: Mu Y; Zhao C; Toni N; Yao J; Gage FH
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.

2015-12 | Journal article
DOI: 10.1016/j.stem.2015.09.001
PMID: 26456686
Contributors: Mertens J; Paquola AC; Ku M; Hatch E; Böhnke L; Ladjevardi S; McGrath S; Campbell B; Lee H; Herdy JR et al.
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.

2015-11 | Journal article
DOI: 10.1038/nature15526
PMID: 26524527
PMC: PMC4742055
Contributors: Mertens J; Wang QW; Kim Y; Yu DX; Pham S; Yang B; Zheng Y; Diffenderfer KE; Zhang J; Soltani S et al.
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Exosome and exosomal microRNA: trafficking, sorting, and function.

2015-02 | Journal article
DOI: 10.1016/j.gpb.2015.02.001
PMID: 25724326
PMC: PMC4411500
Contributors: Zhang J; Li S; Li L; Li M; Guo C; Yao J; Mi S
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Modeling hippocampal neurogenesis using human pluripotent stem cells.

2014-03 | Journal article
DOI: 10.1016/j.stemcr.2014.01.009
PMID: 24672753
PMC: PMC3964286
Contributors: Yu DX; Di Giorgio FP; Yao J; Marchetto MC; Brennand K; Wright R; Mei A; McHenry L; Lisuk D; Grasmick JM et al.
Source: Self-asserted source
Jun Yao via Europe PubMed Central

All three components of the neuronal SNARE complex contribute to secretory vesicle docking.

2012-08 | Journal article
DOI: 10.1083/jcb.201106158
PMID: 22869597
PMC: PMC3413369
Contributors: Wu Y; Gu Y; Morphew MK; Yao J; Yeh FL; Dong M; Chapman ER
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Neural stem cells: mechanisms and modeling.

2012-04 | Journal article
DOI: 10.1007/s13238-012-2033-6
PMID: 22549585
PMC: PMC4875476
Contributors: Yao J; Mu Y; Gage FH
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Uncoupling the roles of synaptotagmin I during endo- and exocytosis of synaptic vesicles.

2011-12 | Journal article
DOI: 10.1038/nn.3013
PMID: 22197832
PMC: PMC3435110
Contributors: Yao J; Kwon SE; Gaffaney JD; Dunning FM; Chapman ER
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release.

2011-10 | Journal article
DOI: 10.1016/j.cell.2011.09.046
PMID: 22036572
PMC: PMC3220409
Contributors: Yao J; Gaffaney JD; Kwon SE; Chapman ER
Source: Self-asserted source
Jun Yao via Europe PubMed Central

SV2 mediates entry of tetanus neurotoxin into central neurons.

2010-11 | Journal article
DOI: 10.1371/journal.ppat.1001207
PMID: 21124874
PMC: PMC2991259
Contributors: Yeh FL; Dong M; Yao J; Tepp WH; Lin G; Johnson EA; Chapman ER
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Synaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusion.

2009-08 | Journal article
DOI: 10.1016/j.cell.2009.05.049
PMID: 19703397
PMC: PMC2758036
Contributors: Hui E; Johnson CP; Yao J; Dunning FM; Chapman ER
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Calcium-modulating cyclophilin ligand regulates membrane trafficking of postsynaptic GABA(A) receptors.

2008-06 | Journal article
DOI: 10.1016/j.mcn.2008.03.002
PMID: 18424167
PMC: PMC2350232
Contributors: Yuan X; Yao J; Norris D; Tran DD; Bram RJ; Chen G; Luscher B
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Sequential postsynaptic maturation governs the temporal order of GABAergic and glutamatergic synaptogenesis in rat embryonic cultures.

2007-10 | Journal article
DOI: 10.1523/jneurosci.2744-07.2007
PMID: 17913919
Contributors: Deng L; Yao J; Fang C; Dong N; Luscher B; Chen G
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Downregulation of tonic GABA currents following epileptogenic stimulation of rat hippocampal cultures.

2006-12 | Journal article
DOI: 10.1113/jphysiol.2006.113134
PMID: 16990405
Contributors: Qi JS; Yao J; Fang C; Luscher B; Chen G
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Actin-dependent activation of presynaptic silent synapses contributes to long-term synaptic plasticity in developing hippocampal neurons.

2006-08 | Journal article
DOI: 10.1523/jneurosci.1183-06.2006
PMID: 16885227
Contributors: Yao J; Qi J; Chen G
Source: Self-asserted source
Jun Yao via Europe PubMed Central

Peer review (3 reviews for 3 publications/grants)

Review activity for Molecular psychiatry. (1)
Review activity for Nature communications (1)
Review activity for Nature neuroscience. (1)
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