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Employment (3)

University of Texas Southwestern Medical Center: Dallas, TX, US

2012 to present (Biochemistry)
Employment
Source: Self-asserted source
Andrew Lemoff

Saint Jude Children's Research Hospital: Memphis, TN, US

2007 to 2012
Employment
Source: Self-asserted source
Andrew Lemoff

Pharmaceutical Product Development LLC GMP Lab: Middleton, WI, US

2005 to 2007
Employment
Source: Self-asserted source
Andrew Lemoff

Education and qualifications (2)

University of California Berkeley: Berkeley, CA, US

1999 to 2005 | Ph.D. (Chemistry)
Education
Source: Self-asserted source
Andrew Lemoff

Boston University: Boston, MA, US

1995 to 1999 | BA (Chemistry)
Education
Source: Self-asserted source
Andrew Lemoff

Works (36)

Structural basis for Retriever-SNX17 assembly and endosomal sorting

Nature Communications
2024-11-25 | Journal article
DOI: 10.1038/s41467-024-54583-6
Contributors: Amika Singla; Daniel J. Boesch; Ho Yee Joyce Fung; Chigozie Ngoka; Avery S. Enriquez; Ran Song; Daniel A. Kramer; Yan Han; Esther Banarer; Andrew Lemoff et al.
Source: check_circle
Crossref

Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis

Communications Biology
2024-07-27 | Journal article
DOI: 10.1038/s42003-024-06588-6
Contributors: Binh An Nguyen; Virender Singh; Shumaila Afrin; Preeti Singh; Maja Pekala; Yasmin Ahmed; Rose Pedretti; Jacob Canepa; Andrew Lemoff; Barbara Kluve-Beckerman et al.
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Crossref

PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer

Nature Communications
2024-03-13 | Journal article
DOI: 10.1038/s41467-024-46495-2
Contributors: Chang-Ching Lin; Tsung-Cheng Chang; Yunguan Wang; Lei Guo; Yunpeng Gao; Emmanuel Bikorimana; Andrew Lemoff; Yisheng V. Fang; He Zhang; Yanfeng Zhang et al.
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Crossref

Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis

2024-03-09 | Preprint
DOI: 10.1101/2024.03.08.582936
Contributors: Binh An Nguyen; Virender Singh; Shumaila Afrin; Preeti Singh; Maja Pekala; Yasmin Ahmed; Rose Pedretti; Jacob Canepa; Andrew Lemoff; Barbara Kluve-Beckerman et al.
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Crossref

CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site

Nature Communications
2022-11-09 | Journal article
DOI: 10.1038/s41467-022-34431-1
Contributors: Lihu Gong; Xiuli Liu; Lianying Jiao; Xin Yang; Andrew Lemoff; Xin Liu
Source: check_circle
Crossref

Differential requirements for mitochondrial electron transport chain components in the adult murine liver

eLife
2022-09-26 | Journal article
DOI: 10.7554/eLife.80919
Contributors: Nicholas P Lesner; Xun Wang; Zhenkang Chen; Anderson Frank; Cameron J Menezes; Sara House; Spencer D Shelton; Andrew Lemoff; David G McFadden; Janaka Wansapura et al.
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Crossref

Reactive oxygen species oxidize STING and suppress interferon production

eLife
2020-09-04 | Journal article
DOI: 10.7554/eLife.57837
Contributors: Lili Tao; Andrew Lemoff; Guoxun Wang; Christina Zarek; Alexandria Lowe; Nan Yan; Tiffany A Reese
Source: check_circle
Crossref

PTH/PTHrP Receptor Signaling Restricts Arterial Fibrosis in Diabetic LDLR-/- Mice by Inhibiting Myocardin-Related Transcription Factor Relays.

Circulation research
2020-03 | Journal article
DOI: 10.1161/circresaha.119.316141
PMID: 32160132
Contributors: Behrmann A; Zhong D; Li L; Cheng SL; Mead M; Ramachandran B; Sabaeifard P; Goodarzi M; Lemoff A; Kronenberg HM et al.
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Improved strategy for isoleucine 1H/13C methyl labeling in Pichia pastoris.

Journal of biomolecular NMR
2019-09 | Journal article
DOI: 10.1007/s10858-019-00281-1
PMID: 31541396
PMC: PMC6875547
Contributors: Ali R; Clark LD; Zahm JA; Lemoff A; Ramesh K; Rosenbaum DM; Rosen MK
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Yeast Ataxin-2 Forms an Intracellular Condensate Required for the Inhibition of TORC1 Signaling during Respiratory Growth.

Cell
2019-04 | Journal article
DOI: 10.1016/j.cell.2019.02.043
PMID: 30982600
PMC: PMC6752053
Contributors: Yang YS; Kato M; Wu X; Litsios A; Sutter BM; Wang Y; Hsu CH; Wood NE; Lemoff A; Mirzaei H et al.
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

A dual regulatory circuit consisting of S-adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma brucei.

PLoS pathogens
2018-10 | Journal article
DOI: 10.1371/journal.ppat.1007404
PMID: 30365568
PMC: PMC6221367
Contributors: Patel MM; Volkov OA; Leija C; Lemoff A; Phillips MA
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

A GTPase-activating protein-binding protein (G3BP1)/antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells.

The Journal of biological chemistry
2018-04 | Journal article
DOI: 10.1074/jbc.ra118.002046
PMID: 29626090
PMC: PMC5971440
Contributors: Ramachandran B; Stabley JN; Cheng SL; Behrmann AS; Gay A; Li L; Mead M; Kozlitina J; Lemoff A; Mirzaei H et al.
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells.

RNA (New York, N.Y.)
2016-05 | Journal article
DOI: 10.1261/rna.056499.116
PMID: 27198507
PMC: PMC4911916
Contributors: Kalantari R; Hicks JA; Li L; Gagnon KT; Sridhara V; Lemoff A; Mirzaei H; Corey DR
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.

Nature chemical biology
2016-02 | Journal article
DOI: 10.1038/nchembio.2016
PMID: 26829472
PMC: PMC4798879
Contributors: Theodoropoulos PC; Gonzales SS; Winterton SE; Rodriguez-Navas C; McKnight JS; Morlock LK; Hanson JM; Cross B; Owen AE; Duan Y et al.
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents.

Journal of medicinal chemistry
2016-01 | Journal article
DOI: 10.1021/acs.jmedchem.5b01092
PMID: 26632965
Contributors: Min J; Guo K; Suryadevara PK; Zhu F; Holbrook G; Chen Y; Feau C; Young BM; Lemoff A; Connelly MC et al.
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Fucosylation and protein glycosylation create functional receptors for cholera toxin.

eLife
2015-10 | Journal article
DOI: 10.7554/elife.09545
PMID: 26512888
PMC: PMC4686427
Contributors: Wands AM; Fujita A; McCombs JE; Cervin J; Dedic B; Rodriguez AC; Nischan N; Bond MR; Mettlen M; Trudgian DC et al.
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Detection of FGF15 in plasma by stable isotope standards and capture by anti-peptide antibodies and targeted mass spectrometry.

Cell metabolism
2015-06 | Journal article
DOI: 10.1016/j.cmet.2015.05.004
PMID: 26039452
PMC: PMC4454892
Contributors: Katafuchi T; Esterházy D; Lemoff A; Ding X; Sondhi V; Kliewer SA; Mirzaei H; Mangelsdorf DJ
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Confetti: a multiprotease map of the HeLa proteome for comprehensive proteomics.

Molecular & cellular proteomics : MCP
2014-04 | Journal article
DOI: 10.1074/mcp.m113.035170
PMID: 24696503
PMC: PMC4047476
Contributors: Guo X; Trudgian DC; Lemoff A; Yadavalli S; Mirzaei H
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").

Journal of natural products
2013-01 | Journal article
DOI: 10.1021/np300628a
PMID: 23286284
PMC: PMC3556224
Contributors: Hatfield MJ; Tsurkan LG; Hyatt JL; Edwards CC; Lemoff A; Jeffries C; Yan B; Potter PM
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Lead optimization of antimalarial propafenone analogues.

Journal of medicinal chemistry
2012-06 | Journal article
DOI: 10.1021/jm300286a
PMID: 22708838
PMC: PMC4408918
Contributors: Lowes D; Pradhan A; Iyer LV; Parman T; Gow J; Zhu F; Furimsky A; Lemoff A; Guiguemde WA; Sigal M et al.
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Synthesis and evaluation of sulfonylnitrophenylthiazoles (SNPTs) as thyroid hormone receptor-coactivator interaction inhibitors.

Journal of medicinal chemistry
2012-02 | Journal article
DOI: 10.1021/jm201546m
PMID: 22324546
PMC: PMC3308170
Contributors: Hwang JY; Attia RR; Zhu F; Yang L; Lemoff A; Jeffries C; Connelly MC; Guy RK
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Optimization of propafenone analogues as antimalarial leads.

Journal of medicinal chemistry
2011-10 | Journal article
DOI: 10.1021/jm2005546
PMID: 21955244
PMC: PMC3208124
Contributors: Lowes DJ; Guiguemde WA; Connelly MC; Zhu F; Sigal MS; Clark JA; Lemoff AS; Derisi JL; Wilson EB; Guy RK
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

IDH1 and IDH2 mutations in pediatric acute leukemia.

Leukemia
2011-06 | Journal article
DOI: 10.1038/leu.2011.133
PMID: 21647154
PMC: PMC3883450
Contributors: Andersson AK; Miller DW; Lynch JA; Lemoff AS; Cai Z; Pounds SB; Radtke I; Yan B; Schuetz JD; Rubnitz JE et al.
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Functional regulation of cystic fibrosis transmembrane conductance regulator-containing macromolecular complexes: a small-molecule inhibitor approach.

The Biochemical journal
2011-04 | Journal article
DOI: 10.1042/bj20101725
PMID: 21299497
PMC: PMC3177239
Contributors: Zhang W; Penmatsa H; Ren A; Punchihewa C; Lemoff A; Yan B; Fujii N; Naren AP
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Evaluation of Diarylureas for Activity Against Plasmodium falciparum.

ACS medicinal chemistry letters
2010-12 | Journal article
DOI: 10.1021/ml100083c
PMID: 21243104
PMC: PMC3019604
Contributors: Zhang Y; Anderson M; Weisman JL; Lu M; Choy CJ; Boyd VA; Price J; Sigal M; Clark J; Connelly M et al.
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models.

Bioorganic & medicinal chemistry
2010-10 | Journal article
DOI: 10.1016/j.bmc.2010.09.073
PMID: 21051236
Contributors: Mallari JP; Zhu F; Lemoff A; Kaiser M; Lu M; Brun R; Guy RK
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Structural confirmation and quantification of individual ligands from the surface of multi-functionalized gold nanoparticles.

The Analyst
2010-03 | Journal article
DOI: 10.1039/c0an00066c
PMID: 20498874
PMC: PMC4815266
Contributors: Zhou H; Li X; Lemoff A; Zhang B; Yan B
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Dual Detection Approach to a More Accurate Measure of Relative Purity in High-Throughput Characterization of Compound Collections

Journal of Combinatorial Chemistry
2008-09-08 | Journal article
DOI: 10.1021/cc800100g
Part of ISSN: 1520-4766
Contributors: Andrew Lemoff; Bing Yan
Source: Self-asserted source
Andrew Lemoff via Crossref Metadata Search

Structures of lithiated lysine and structural analogues in the gas phase: effects of water and proton affinity on zwitterionic stability.

The journal of physical chemistry. A
2006-07 | Journal article
DOI: 10.1021/jp057436r
PMID: 16821826
Contributors: Lemoff AS; Bush MF; O'Brien JT; Williams ER
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Binding energies of water to doubly hydrated cationized glutamine and structural analogues in the gas phase.

The journal of physical chemistry. A
2006-03 | Journal article
DOI: 10.1021/jp055662v
PMID: 16526649
Contributors: Lemoff AS; Wu CC; Bush MF; Williams ER
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Structures and hydration enthalpies of cationized glutamine and structural analogues in the gas phase.

Journal of the American Chemical Society
2005-07 | Journal article
DOI: 10.1021/ja051743t
PMID: 16028939
Contributors: Lemoff AS; Bush MF; Wu CC; Williams ER
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Structures of cationized proline analogues: evidence for the zwitterionic form.

The journal of physical chemistry. A
2005-03 | Journal article
DOI: 10.1021/jp0466800
PMID: 16833523
Contributors: Lemoff AS; Bush MF; Williams ER
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Binding energies of water to lithiated valine: formation of solution-phase structure in vacuo.

Journal of the American Society for Mass Spectrometry
2004-07 | Journal article
DOI: 10.1016/j.jasms.2004.04.001
PMID: 15234361
Contributors: Lemoff AS; Williams ER
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Binding energies of water to sodiated valine and structural isomers in the gas phase: the effect of proton affinity on zwitterion stability.

Journal of the American Chemical Society
2003-11 | Journal article
DOI: 10.1021/ja034544n
PMID: 14583055
Contributors: Lemoff AS; Bush MF; Williams ER
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Effect of metal ion and water coordination on the structure of a gas-phase amino acid.

Journal of the American Chemical Society
2001-12 | Journal article
DOI: 10.1021/ja0106873
PMID: 11734026
Contributors: Jockusch RA; Lemoff AS; Williams ER
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Structure of cationized glycine, gly.m (m = be, mg, ca, sr, ba), in the gas phase: intrinsic effect of cation size on zwitterion stability.

The journal of physical chemistry. A
2000-11 | Journal article
DOI: 10.1021/jp002970e
PMID: 16467899
PMC: PMC1343513
Contributors: Strittmatter EF; Lemoff AS; Williams ER
Source: Self-asserted source
Andrew Lemoff via Europe PubMed Central

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
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