Personal information

Activities

Employment (3)

University of Massachusetts Chan Medical School TH Chan School of Medicine: Worcester, MA, US

2022-11-29 to present | Assistant Professor (Pediatrics)
Employment
Source: Self-asserted source
Sumeda Nandadasa

Cleveland Clinic Lerner Research Institute: Cleveland, OH, US

2015-12-01 to 2020-12-31 | Research Associate (Biomedical Engineering )
Employment
Source: Self-asserted source
Sumeda Nandadasa

Cleveland Clinic Lerner Research Institute: Cleveland, OH, US

2012-04-01 to 2015-11-30 | Postdoctoral Fellow (Biomedical Engineering)
Employment
Source: Self-asserted source
Sumeda Nandadasa

Education and qualifications (2)

University of Cincinnati College of Medicine: Cincinnati, OH, US

2005-07-01 to 2010-06-15 | PhD
Education
Source: Self-asserted source
Sumeda Nandadasa

Minnesota State University Moorhead: Moorhead, MN, US

2001-08-15 to 2005-05-15 | B.A.
Education
Source: Self-asserted source
Sumeda Nandadasa

Works (16)

Two functional forms of the Meckel-Gruber syndrome protein TMEM67 generated by proteolytic cleavage by ADAMTS9 mediate Wnt signaling and ciliogenesis

2024-09-05 | Preprint
Contributors: Manu Ahmed; Sydney Fischer; Karyn L. Robert; Karen I. Lange; Michael W. Stuck; Sunayna Best; Colin A. Johnson; Gregory J. Pazour; Oliver E. Blacque; Sumeda Nandadasa
Source: check_circle
Crossref

Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate

Molecular & Cellular Proteomics
2023-06 | Journal article
Contributors: Sumeda Nandadasa; Daniel Martin; Gauravi Deshpande; Karyn L. Robert; M. Sharon Stack; Yoshifumi Itoh; Suneel S. Apte
Source: check_circle
Crossref

A new mouse mutant with cleavage-resistant versican and isoform-specific versican mutants demonstrate that proteolysis at the Glu441-Ala442 peptide bond in the V1 isoform is essential for interdigital web regression

Matrix Biology Plus
2021-06 | Journal article
Part of ISSN: 2590-0285
Contributors: Sumeda Nandadasa
Source: Self-asserted source
Sumeda Nandadasa

The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1+ hematoendothelial progenitors

Matrix Biology
2021-03 | Journal article
Part of ISSN: 0945-053X
Contributors: Sumeda Nandadasa
Source: Self-asserted source
Sumeda Nandadasa

Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth

eLife
2020-09-10 | Journal article
Contributors: Sumeda Nandadasa; Jason M Szafron; Vai Pathak; Sae-Il Murtada; Caroline M Kraft; Anna O'Donnell; Christian Norvik; Clare Hughes; Bruce Caterson; Miriam S Domowicz et al.
Source: check_circle
Crossref

A disintegrin-like and metalloproteinase domain with thrombospondin type 1 motif 9 (ADAMTS9) regulates fibronectin fibrillogenesis and turnover

Journal of Biological Chemistry
2019 | Journal article
EID:

2-s2.0-85068457652

Part of ISBN:

1083351X 00219258

Contributors: Wang, L.W.; Nandadasa, S.; Annis, D.S.; Dubail, X.J.; Mosher, D.F.; Willard, B.B.; Apte, S.S.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

Mutations of ADAMTS9 Cause Nephronophthisis-Related Ciliopathy

American Journal of Human Genetics
2019 | Journal article
EID:

2-s2.0-85058228694

Part of ISBN:

15376605 00029297

Contributors: Choi, Y.J.; Halbritter, J.; Braun, D.A.; Schueler, M.; Schapiro, D.; Rim, J.H.; Nandadasa, S.; Choi, W.-I.; Widmeier, E.; Shril, S. et al.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis

Nature Communications
2019 | Journal article
EID:

2-s2.0-85062261861

Part of ISBN:

20411723

Contributors: Nandadasa, S.; Kraft, C.M.; Wang, L.W.; O’Donnell, A.; Patel, R.; Gee, H.Y.; Grobe, K.; Cox, T.C.; Hildebrandt, F.; Apte, S.S.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis

Scientific Reports
2017 | Journal article
EID:

2-s2.0-85042385173

Part of ISBN:

20452322

Contributors: Asano, K.; Nelson, C.M.; Nandadasa, S.; Aramaki-Hattori, N.; Lindner, D.J.; Alban, T.; Inagaki, J.; Ohtsuki, T.; Oohashi, T.; Apte, S.S. et al.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion

Developmental Biology
2016 | Journal article
EID:

2-s2.0-84989300287

Part of ISBN:

1095564X 00121606

Contributors: Benz, B.A.; Nandadasa, S.; Takeuchi, M.; Grady, R.C.; Takeuchi, H.; LoPilato, R.K.; Kakuda, S.; Somerville, R.P.T.; Apte, S.S.; Haltiwanger, R.S. et al.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation

Cell Reports
2015 | Journal article
EID:

2-s2.0-84937629934

Part of ISBN:

22111247

Contributors: Nandadasa, S.; Nelson, C.M.; Apte, S.S.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

The multiple, complex roles of versican and its proteolytic turnover by ADAMTS proteases during embryogenesis

Matrix Biology
2014 | Journal article
EID:

2-s2.0-84901465036

Part of ISBN:

15691802 0945053X

Contributors: Nandadasa, S.; Foulcer, S.; Apte, S.S.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

Regulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesis

PLoS ONE
2012 | Journal article
EID:

2-s2.0-84862237259

Part of ISBN:

19326203

Contributors: Nandadasa, S.; Tao, Q.; Shoemaker, A.; Cha, S.-w.; Wylie, C.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of xenopus neural tube morphogenesis

Development
2010 | Journal article
EID:

2-s2.0-77951244400

Part of ISBN:

09501991 14779129

Contributors: Morita, H.; Nandadasa, S.; Yamamoto, T.S.; Terasaka-Iioka, C.; Wylie, C.; Ueno, N.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

N- and E-cadherins in Xenopus are specifically required in the neural and non-neural ectoderm, respectively, for F-actin assembly and morphogenetic movements

Development
2009 | Journal article
EID:

2-s2.0-67650760556

Part of ISBN:

09501991 14779129

Contributors: Nandadasa, S.; Tao, Q.; Menon, N.R.; Heasman, J.; Wylie, C.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

G-protein-coupled signals control cortical actin assembly by controlling cadherin expression in the early Xenopus embryo

Development
2007 | Journal article
EID:

2-s2.0-34547727349

Part of ISBN:

09501991

Contributors: Tao, Q.; Nandadasa, S.; McCrea, P.D.; Heasman, J.; Wylie, C.
Source: Self-asserted source
Sumeda Nandadasa via Scopus - Elsevier

Peer review (2 reviews for 2 publications/grants)

Review activity for Nature communications (1)
Review activity for PLoS biology. (1)