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addiction, cocaine, opiates, tobacco, alcohol, bipolar disorder, comorbidity, integrated treatment, next generation sequencing, genomics, bioinformatics
France

Activities

Employment (2)

Assistance Publique -Hopitaux De Paris: Paris, FR

2011-01-11 to present | Hospital Practitioner (Psychiatry and Addiction Medicine, Fernand Widal Hospital)
Employment
Source: Self-asserted source
Romain Icick

INSERM: Paris, Île-de-France, FR

2008-01-11 to present | part-time researcher (UMR-S1144 'variability of response to psychotropics')
Employment
Source: Self-asserted source
Romain Icick

Education and qualifications (3)

Université Paris Descartes: Paris, Île-de-France, FR

2017-11-27 to present | Doctor of Philosophy in neurosciences
Education
Source: Self-asserted source
Romain Icick

Maastricht University: Maastricht, Limburg, NL

2010-07-10 to present | Master of science (Affective Neurosciences)
Education
Source: Self-asserted source
Romain Icick

Université de Bordeaux Faculté de Médecine Paul Broca: Bordeaux, Aquitaine, FR

2008-10-17 to present | Doctor of Medicine
Education
Source: Self-asserted source
Romain Icick

Funding (2)

Reinforcing PhD projects in the International Collaboration on ADHD and Substance Abuse (ICASA)

2021-06 to 2024-06 | Grant
Institut pour la Recherche en Santé Publique (Paris, FR)
Source: Self-asserted source
Romain Icick

Nicotinic Receptor genes in cocaine addiction

Source: Self-asserted source
Romain Icick

Works (32)

Identification of risk variants and cross-disorder pleiotropy through multi-ancestry genome-wide analysis of alcohol use disorder

Nature Mental Health
2025-01-08 | Journal article
Contributors: Romain Icick; Alexey Shadrin; Børge Holen; Naz Karadag; Nadine Parker; Kevin S. O’Connell; Oleksandr Frei; Shahram Bahrami; Margrethe Collier Høegh; Trine Vik Lagerberg et al.
Source: check_circle
Crossref

Predictors of abstinence maintenance after cocaine inpatient detoxification: A prospective study

The American Journal on Addictions
2024-09 | Journal article
Contributors: Margaux Poireau; Virgile Clergue‐Duval; Angéline Maillard; Romain Icick; Julien Azuar; Pauline Smith; Mathieu Faurent; Emmanuelle Volle; Christine Delmaire; Julien Cabé et al.
Source: check_circle
Crossref

Genome-wide analyses reveal shared genetic architecture and novel risk loci between opioid use disorder and general cognitive ability

Drug and Alcohol Dependence
2024-03 | Journal article
Contributors: Børge Holen; Gleda Kutrolli; Alexey A. Shadrin; Romain Icick; Guy Hindley; Linn Rødevand; Kevin S. O’Connell; Oleksandr Frei; Nadine Parker; Markos Tesfaye et al.
Source: check_circle
Crossref

Identification of Novel Loci and Cross-Disorder Pleiotropy Through Multi-Ancestry Genome-Wide Analysis of Alcohol Use Disorder in Over One Million Individuals

2023-12-22 | Preprint
Contributors: Romain Icick; Alexey Shadrin; Børge Holen; Naz Karadag; Nadine Parker; Kevin O'Connell; Oleksandr Frei; Shahram Bahrami; Margrethe Høegh; Trine Lagerberg et al.
Source: check_circle
Crossref

Genome‐wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression

Addiction Biology
2023-06 | Journal article
Contributors: Børge Holen; Alexey A. Shadrin; Romain Icick; Tahir T. Filiz; Guy Hindley; Linn Rødevand; Kevin S. O'Connell; Espen Hagen; Oleksandr Frei; Shahram Bahrami et al.
Source: check_circle
Crossref

Childhood Trauma and the Severity of past Suicide Attempts in Outpatients with Cocaine use Disorders

Substance Abuse
2022-12 | Journal article
Contributors: Romain Icick; Emily Karsinti; Georges Brousse; Clara Chrétienneau; Jean-Baptiste Trabut; Beatriz Belforte; Philippe Coeuru; Delphine Moisan; Alice Deschenau; Olivier Cottencin et al.
Source: check_circle
Crossref

USP7/Maged1-Mediated H2A Monoubiquitination in the Paraventricular Thalamus: An Epigenetic Mechanism Involved in Cocaine Use Disorder

2022-11-17 | Preprint
Contributors: Julian Cheron; Leonardo Beccari; Perrine Hagué; Romain Icick; Chloé Despontin; Teresa Carusone; Mathieu Defrance; Sagar Bhogaraju; Elena Martin-Garcia; Roberto Capellan et al.
Source: check_circle
Crossref

Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings

Neuropsychopharmacology
2022-10 | Journal article
Contributors: Romain Icick; Alexey Shadrin; Børge Holen; Naz Karadag; Aihua Lin; Guy Hindley; Kevin O’Connell; Oleksandr Frei; Shahram Bahrami; Margrethe Collier Høegh et al.
Source: check_circle
Crossref

Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression

2022-09-09 | Preprint
Contributors: Børge Holen; Alexey A. Shadrin; Romain Icick; Guy Hindley; Linn Rødevand; Kevin S. O’Connell; Oleksandr Frei; Shahram Bahrami; Weiqiu Cheng; Nadine Parker et al.
Source: check_circle
Crossref

What is the potential for abuse of lisdexamfetamine in adults? A preclinical and clinical literature review and expert opinion

Expert Review of Clinical Pharmacology
2022-08-03 | Journal article
Contributors: Louise Carton; Romain Icick; Sébastien Weibel; Maurice Dematteis; Etienne Kammerer; Anne Batisse; Benjamin Rolland
Source: check_circle
Crossref

Biomarkers of Relapse in Cocaine Use Disorder: A Narrative Review

Brain Sciences
2022-07-30 | Journal article
Contributors: Margaux Poireau; Thomas Milpied; Angéline Maillard; Christine Delmaire; Emmanuelle Volle; Frank Bellivier; Romain Icick; Julien Azuar; Cynthia Marie-Claire; Vanessa Bloch et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings

2022-03-10 | Preprint
Contributors: Romain Icick; Alexey Shadrin; Børge Holen; Naz Karadag; Aihua Lin; Guy Hindley; Kevin O’Connell; Oleksandr Frei; Shahram Bahrami; Margrethe Collier Høegh et al.
Source: check_circle
Crossref

The course of bipolar disorder as a function of the presence and sequence of onset of comorbid alcohol use disorders in outpatients attending the Fondamental Advanced Centres of Expertise

Journal of Affective Disorders
2021-05 | Journal article
Contributors: Romain Icick; Sébastien Gard; Katia M'Bailara; Isabelle Biseul; Ludovic Samalin; Georges Brousse; Valentin Flaudias; Pierre-Michel Llorca; Joséphine Loftus; Iréna Cussac et al.
Source: check_circle
Crossref

Alterations in nicotinic receptor alpha5 subunit gene differentially impact early and later stages of cocaine addiction: a translational study in transgenic rats and patients

Progress in Neurobiology
2021-02 | Journal article
Contributors: Benoît Forget; Romain Icick; Jonathan Robert; Caroline Correia; Marie S. Prevost; Marc Gielen; Pierre-Jean Corringer; Frank Bellivier; Florence Vorspan; Morgane Besson et al.
Source: check_circle
Crossref

Clustering suicidal phenotypes and genetic associations with brain-derived neurotrophic factor in patients with substance use disorders

Translational Psychiatry
2021-01-21 | Journal article
Contributors: Romain Icick; Vanessa Bloch; Nathalie Prince; Emily Karsinti; Jean-Pierre Lépine; Jean-Louis Laplanche; Stéphane Mouly; Cynthia Marie-Claire; Georges Brousse; Frank Bellivier et al.
Source: check_circle
Crossref

Translational study of the whole transcriptome in rats and genetic polymorphisms in humans identifies LRP1B and VPS13A as key genes involved in tolerance to cocaine-induced motor disturbances

Translational Psychiatry
2020-11-06 | Journal article
Contributors: Florence Vorspan; Romain Icick; Nawel Mekdad; Cindie Courtin; Vanessa Bloch; Frank Bellivier; Jean-Louis Laplanche; Nathalie Prince; Dmitry Pishalin; Cyril Firmo et al.
Source: check_circle
Crossref

Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder

Journal of Affective Disorders
2019-09 | Journal article
Contributors: R. Icick; I. Melle; B. Etain; P.A. Ringen; S.R. Aminoff; M. Leboyer; M. Aas; C. Henry; T.D. Bjella; O.A. Andreassen et al.
Source: check_circle
Crossref

Gene-Gene interactions and pleiotropy in the brain nicotinic pathway associated with the heaviness and precocity of tobacco smoking among outpatients with multiple substance use disorders

2019-09-25 | Other
Contributors: Romain Icick; Morgane Besson; El-Hadi Zerdazi; Nathalie Prince; Vanessa Bloch; Jean-Louis Laplanche; Philippe Faure; Frank Bellivier; Uwe Maskos; Florence Vorspan
Source: check_circle
Crossref

Gender-specific study of recurrent suicide attempts in outpatients with multiple substance use disorders

Journal of Affective Disorders
2018-12 | Journal article
Contributors: R. Icick; F. Vorspan; E. Karsinti; K. Ksouda; J-P. Lépine; G. Brousse; S. Mouly; F. Bellivier; V. Bloch
Source: check_circle
Crossref

Alcohol use disorders are associated with increased affective lability in bipolar disorder

Journal of Affective Disorders
2017 | Journal article
EID:

2-s2.0-84992747316

Contributors: Lagerberg, T.V.; Aminoff, S.R.; Aas, M.; Bjella, T.; Henry, C.; Leboyer, M.; Pedersen, G.; Bellivier, F.; Icick, R.; Andreassen, O.A. et al.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

Physical and mental health burden in cases of bipolar disorder classified as current, former, or non-tobacco smokers

Journal of Affective Disorders
2017 | Journal article
EID:

2-s2.0-84994217943

Contributors: Icick, R.; Gard, S.; Barde, M.; Carminati, M.; Desage, A.; Guillaume, S.; Scott, J.; Bellivier, F.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

The motor semiology in psychiatry: A forgotten dimension! | La sémiologie motrice en psychiatrie : une dimension oubliée !

Annales Medico-Psychologiques
2017 | Journal article
EID:

2-s2.0-85018772143

Contributors: Geoffroy, P.A.; Fovet, T.; Franchi, J.-A.M.; Quiles, C.; Icick, R.; Benzerouk, F.; Yrondi, A.; Peyre, H.; Rolland, B.; Amad, A.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

Serious suicide attempts in outpatients with multiple substance use disorders

Drug and Alcohol Dependence
2017-12 | Journal article
Contributors: R. Icick; E. Karsinti; J-P. Lépine; V. Bloch; G. Brousse; F. Bellivier; F. Vorspan
Source: check_circle
Crossref

Feasibility and Acceptability of the ‘HABIT’ Group Programme for Comorbid Bipolar and Alcohol and Substance use Disorders

Clinical Psychology & Psychotherapy
2017-07 | Journal article
Contributors: Isabelle Biseul; Romain Icick; Perrine Seguin; Frank Bellivier; Jan Scott
Source: check_circle
Crossref

Anxiety disorders are associated with early onset of heroin use and rapid transition to dependence in methadone maintained patients

Psychiatry Research
2016 | Journal article
EID:

2-s2.0-84986910135

Contributors: Karsinti, E.; Fortias, M.; Dupuy, G.; Ksouda, K.; Laqueille, X.; Simonpoli, A.-M.; Touzeau, D.; Avril, E.; Orizet, C.; Belforte, B. et al.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

Cannabis use disorder is associated with greater illness severity in tobacco smoking patients with bipolar disorder

Journal of Affective Disorders
2016 | Journal article
EID:

2-s2.0-84946143540

Contributors: Lagerberg, T.V.; Icick, R.; Andreassen, O.A.; Ringen, P.A.; Etain, B.; Aas, M.; Henry, C.; Bjella, T.D.; Melle, I.; Bellivier, F.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

A cannabinoid receptor 1 polymorphism is protective against major depressive disorder in methadone-maintained outpatients

American Journal on Addictions
2015 | Journal article
EID:

2-s2.0-84942551473

Contributors: Icick, R.; Peoc'H, K.; Karsinti, E.; Ksouda, K.; Hajj, A.; Bloch, V.; Prince, N.; Mouly, S.; Bellivier, F.; Lépine, J.-P. et al.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

Days out of role due to common mental and physical disorders: French results from the WHO World Mental Health surveys | Perte d'activité due à des problèmes de santé habituels : résultats français de l'étude OMS sur les troubles mentaux (WMH)

L'Encéphale
2014 | Journal article
EID:

2-s2.0-85027955488

Contributors: Icick, R.; Kovess, V.; Gasquet, I.; Lépine, J.-P.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

OPRM1 polymorphism and lifetime suicide attempts among stabilized, methadone-maintained outpatients

Psychiatry Research
2014 | Journal article
EID:

2-s2.0-84902084266

Contributors: Icick, R.; Peoc'h, K.; Ksouda, K.; Bloch, V.; Laplanche, J.L.; Lépine, J.P.; Bellivier, F.; Vorspan, F.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

Predictive value of baseline resistance in early response to antidepressants

Journal of Affective Disorders
2014 | Journal article
EID:

2-s2.0-84898011391

Contributors: Icick, R.; Millet, É.; Curis, E.; Bellivier, F.; Lépine, J.-P.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

Dysfunctional parental styles perceived during childhood in outpatients with substance use disorders

Psychiatry Research
2013 | Journal article
EID:

2-s2.0-84886948588

Contributors: Icick, R.; Lauer, S.; Romo, L.; Dupuy, G.; Lépine, J.-P.; Vorspan, F.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

Comorbid addiction in bipolar affective disorder

Neuropsychiatry
2012 | Journal article
EID:

2-s2.0-84871272463

Contributors: Icick, R.; Desage, A.; Gard, S.; Guillaume, S.; Lépine, J.-P.; Bellivier, F.
Source: Self-asserted source
Romain Icick via Scopus - Elsevier

Peer review (26 reviews for 16 publications/grants)

Review activity for Addiction biology. (3)
Review activity for Addictive behaviors. (1)
Review activity for Biodata mining. (2)
Review activity for BMJ open. (2)
Review activity for Child abuse & neglect. (2)
Review activity for Clinical psychology & psychotherapy. (2)
Review activity for CNS drugs (1)
Review activity for Current drug abuse reviews. (1)
Review activity for Drug and alcohol dependence. (1)
Review activity for Exploration of medicine. (2)
Review activity for Nature mental health. (1)
Review activity for PloS one. (2)
Review activity for Psychiatry research. (1)
Review activity for Psychological medicine. (2)
Review activity for The American journal of psychiatry. (2)
Review activity for The neuroscientist (1)