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Loop profile: 1902312

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Employment (3)

U.S. Department of Veterans Affairs: Philadelphia, US

2022 to 2022 | ORD/OMHSP Liaison
Employment
Source: Self-asserted source
Emily Hartwell

University of Pennsylvania: Philadelphia, PA, US

2018-09 to 2022 | Post doctoral fellow
Employment
Source: Self-asserted source
Emily Hartwell

VA Medical Center Corporal Michael J Crescenz: Philadelphia, PA, US

2018 to 2021 | Post doctoral fellow
Employment
Source: Self-asserted source
Emily Hartwell

Education and qualifications (1)

University of California Los Angeles: Los Angeles, CA, US

Education
Source: Self-asserted source
Emily Hartwell

Works (50)

Next‐generation biomarkers for alcohol consumption and alcohol use disorder diagnosis, prognosis, and treatment: A critical review

Alcohol, Clinical and Experimental Research
2025-01 | Journal article
DOI: 10.1111/acer.15476
Contributors: Shaunna L. Clark; Emily E. Hartwell; Doo‐Sup Choi; John H. Krystal; Robert O. Messing; Laura B. Ferguson
Source: check_circle
Crossref

Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and somatic traits

Neuropsychopharmacology
2024-12 | Journal article
DOI: 10.1038/s41386-024-01922-2
Contributors: Emily E. Hartwell; Zeal Jinwala; Jackson Milone; Sarah Ramirez; Joel Gelernter; Henry R. Kranzler; Rachel L. Kember
Source: check_circle
Crossref

Predicting Treatment-seeking Status for Alcohol Use Disorder Using Polygenic Scores and Machine Learning in a Deeply-Phenotyped Sample

2024-11-23 | Preprint
DOI: 10.1101/2024.11.22.24317810
Contributors: Zeal Jinwala; ReJoyce Green; Yousef Khan; Joel Gelernter; Rachel L. Kember; Emily E. Hartwell
Source: check_circle
Crossref

Author Correction: A multi-ancestry genetic study of pain intensity in 598,339 veterans

Nature Medicine
2024-07 | Journal article
DOI: 10.1038/s41591-024-03024-4
Contributors: Sylvanus Toikumo; Rachel Vickers-Smith; Zeal Jinwala; Heng Xu; Divya Saini; Emily E. Hartwell; Mirko Pavicic; Kyle A. Sullivan; Ke Xu; Daniel A. Jacobson et al.
Source: check_circle
Crossref

Identifying neurofunctional domains across substance use disorders

The American Journal of Drug and Alcohol Abuse
2024-07-03 | Journal article
DOI: 10.1080/00952990.2024.2368180
Contributors: Emily E. Hartwell; Melanie Schwandt; Yaira Z. Nunez; Reagan R. Wetherill; Rachel L. Kember; Corinde E. Wiers; Joel Gelernter; Henry R. Kranzler
Source: check_circle
Crossref

Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans

2024-05-16 | Preprint
DOI: 10.1101/2024.05.16.24307486
Contributors: Christal N. Davis; Zeal Jinwala; Alexander S. Hatoum; Sylvanus Toikumo; Arpana Agrawal; Christopher T. Rentsch; Howard J. Edenberg; James W. Baurley; Emily E. Hartwell; Richard C. Crist et al.
Source: check_circle
Crossref

Combining Transdiagnostic and Disorder-Level GWAS Enhances Precision of Psychiatric Genetic Risk Profiles in a Multi-Ancestry Sample

2024-05-10 | Preprint
DOI: 10.1101/2024.05.09.24307111
Contributors: Yousef Khan; Christal N. Davis; Zeal Jinwala; Kyra L. Feuer; Sylvanus Toikumo; Emily E. Hartwell; Sandra Sanchez-Roige; Roseann E. Peterson; Alexander S. Hatoum; Henry R. Kranzler et al.
Source: check_circle
Crossref

A multi-ancestry genetic study of pain intensity in 598,339 veterans

Nature Medicine
2024-04 | Journal article
DOI: 10.1038/s41591-024-02839-5
Contributors: Sylvanus Toikumo; Rachel Vickers-Smith; Zeal Jinwala; Heng Xu; Divya Saini; Emily E. Hartwell; Mirko Pavicic; Kyle A. Sullivan; Ke Xu; Daniel A. Jacobson et al.
Source: check_circle
Crossref

Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits

2024-01-23 | Preprint
DOI: 10.1101/2024.01.22.24301615
Contributors: Emily E. Hartwell; Zeal Jinwala; Jackson Milone; Sarah Ramirez; Joel Gelernter; Henry R. Kranzler; Rachel L. Kember
Source: check_circle
Crossref

Does polygenic risk for substance‐related traits predict ages of onset and progression of symptoms?

Addiction
2023-09 | Journal article
DOI: 10.1111/add.16210
Contributors: Henry R. Kranzler; Richard Feinn; Heng Xu; Brendan L. Ho; Divya Saini; Olivia R. Nicastro; Anya Jacoby; Sylvanus Toikumo; Joel Gelernter; Emily E. Hartwell et al.
Source: check_circle
Crossref

Medications for treating alcohol use disorder: A narrative review

Alcohol: Clinical and Experimental Research
2023-07 | Journal article
DOI: 10.1111/acer.15118
Contributors: Henry R. Kranzler; Emily E. Hartwell
Source: check_circle
Crossref

Effects of topiramate therapy on serum bicarbonate concentration in a sample of 10,279 veterans

Alcohol: Clinical and Experimental Research
2023-03 | Journal article
DOI: 10.1111/acer.15011
Contributors: Michelle S. Naps; Shirley H. Leong; Emily E. Hartwell; Christopher T. Rentsch; Henry R. Kranzler
Source: check_circle
Crossref

The genetic architecture of pain intensity in a sample of 598,339 U.S. veterans

2023-03-13 | Preprint
DOI: 10.1101/2023.03.09.23286958
Contributors: Sylvanus Toikumo; Rachel Vickers-Smith; Zeal Jinwala; Heng Xu; Divya Saini; Emily Hartwell; Mirko P. Venegas; Kyle A. Sullivan; Ke Xu; Daniel A. Jacobson et al.
Source: check_circle
Crossref

Association of topiramate prescribed for any indication with reduced alcohol consumption in electronic health record data

Addiction
2022-11 | Journal article
DOI: 10.1111/add.15980
Contributors: Henry R. Kranzler; Shirley H. Leong; Michelle Naps; Emily E. Hartwell; David A. Fiellin; Christopher T. Rentsch
Source: check_circle
Crossref

Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction

Nature Neuroscience
2022-10 | Journal article
DOI: 10.1038/s41593-022-01160-z
Contributors: Rachel L. Kember; Rachel Vickers-Smith; Heng Xu; Sylvanus Toikumo; Maria Niarchou; Hang Zhou; Emily E. Hartwell; Richard C. Crist; Christopher T. Rentsch; Lea K. Davis et al.
Source: check_circle
Crossref

Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function

Neuropsychopharmacology
2022-09 | Journal article
DOI: 10.1038/s41386-022-01325-1
Contributors: Tiffany Love; Andrey A. Shabalin; Rachel L. Kember; Anna R. Docherty; Hang Zhou; Vincent Koppelmans; Joel Gelernter; Anne K. Baker; Emily Hartwell; Jacob Dubroff et al.
Source: check_circle
Crossref

Polygenic Risk for Substance-Related Traits Predicts Substance Use Onset and Progression: Sex and Population Group Differences

2022-09-30 | Preprint
DOI: 10.1101/2022.09.29.22280477
Contributors: Henry R. Kranzler; Richard Feinn; Heng Xu; Brendan L. Ho; Divya Saini; Olivia R. Nicastro; Anya Jacoby; Sylvanus Toikumo; Joel Gelernter; Emily E. Hartwell et al.
Source: check_circle
Crossref

Alcohol withdrawal in past‐year drinkers with unhealthy alcohol use: Prevalence, characteristics, and correlates in a national epidemiologic survey

Alcoholism: Clinical and Experimental Research
2022-03 | Journal article
DOI: 10.1111/acer.14781
Contributors: Ofir Livne; Richard Feinn; Justin Knox; Emily E. Hartwell; Joel Gelernter; Deborah S. Hasin; Henry R. Kranzler
Source: check_circle
Crossref

Post‐treatment effects of topiramate on alcohol‐related outcomes: A combined analysis of two placebo‐controlled trials

Addiction Biology
2022-03 | Journal article
DOI: 10.1111/adb.13130
Contributors: Henry R. Kranzler; Richard Feinn; Timothy Pond; Emily Hartwell; Joel Gelernter; Richard C. Crist; Katie Witkiewitz
Source: check_circle
Crossref

Phenome-wide association analysis of substance use disorders in a deeply phenotyped sample

2022-02-10 | Preprint
DOI: 10.1101/2022.02.09.22270737
Contributors: Rachel L. Kember; Emily E. Hartwell; Heng Xu; James Rotenberg; Laura Almasy; Hang Zhou; Joel Gelernter; Henry R. Kranzler
Source: check_circle
Crossref

Genetic liability for substance use associated with medical comorbidities in electronic health records of African‐ and European‐ancestry individuals

Addiction Biology
2022-01 | Journal article
DOI: 10.1111/adb.13099
Contributors: Emily E. Hartwell; Alison K. Merikangas; Shefali S. Verma; Marylyn D. Ritchie; Henry R. Kranzler; Rachel L. Kember
Source: check_circle
Crossref

Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain

2021-12-21 | Preprint
DOI: 10.21203/rs.3.rs-1167873/v1
Contributors: Rachel Kember; Rachel Vickers-Smith; Heng Xu; Sylvanus Toikumo; Maria Niarchou; Hang Zhou; Emily Hartwell; Rick Crist; Christopher Rentsch; Lea Davis et al.
Source: check_circle
Crossref

Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain

2021-12-15 | Preprint
DOI: 10.1101/2021.12.13.21267480
Contributors: Rachel L. Kember; Rachel Vickers-Smith; Heng Xu; Sylvanus Toikumo; Maria Niarchou; Hang Zhou; Emily Hartwell; Richard C. Crist; Christopher T. Rentsch; Lea K. Davis et al.
Source: check_circle
Crossref

Analysis of genetic and clinical factors associated with buprenorphine response

Drug and Alcohol Dependence
2021-10 | Journal article
DOI: 10.1016/j.drugalcdep.2021.109013
Contributors: Richard C. Crist; Rachel Vickers-Smith; Rachel L. Kember; Christopher T. Rentsch; Heng Xu; E. Jennifer Edelman; Emily E. Hartwell; Kyle M. Kampman; Henry R. Kranzler
Source: check_circle
Crossref

World Health Organization risk drinking levels as a treatment outcome measure in topiramate trials

Alcoholism: Clinical and Experimental Research
2021-08 | Journal article
DOI: 10.1111/acer.14652
Contributors: Emily E. Hartwell; Richard Feinn; Katie Witkiewitz; Timothy Pond; Henry R. Kranzler
Source: check_circle
Crossref

Racial Inequalities in Alcohol Use Disorder Diagnosis in a Sample of 700,000 Veterans

2021-07-18 | Other
DOI: 10.1101/2021.07.14.21256113
Contributors: Rachel Vickers-Smith; Amy C. Justice; William C. Becker; Christopher T. Rentsch; Brenda Curtis; Anita Fernander; Emily E. Hartwell; Eseosa T. Ighodaro; Rachel L. Kember; Janet Tate et al.
Source: check_circle
Crossref

Genetic liability for substance use associated with medical comorbidities in electronic health records of African- and European-ancestry individuals

2021-04-22 | Other
DOI: 10.1101/2021.04.19.21255619
Contributors: Emily E. Hartwell; Alison K. Merikangas; Shefali S. Verma; Marylyn D. Ritchie; Henry R. Kranzler; Rachel L. Kember
Source: check_circle
Crossref

Behavioral Economic Demand for Alcohol and Cigarettes in Heavy Drinking Smokers: Evidence of Asymmetric Cross-commodity Reinforcing Value.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
2021-03-01 | Journal article
DOI: 10.1093/ntr/ntaa049
PMID: 33247757
Source: Self-asserted source
Emily Hartwell

Prospective randomized pharmacogenetic study of topiramate for treating alcohol use disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
2021-02-10 | Journal article
DOI: 10.1038/s41386-020-00945-9
PMID: 33568796
Source: Self-asserted source
Emily Hartwell

A Delta-Opioid Receptor Gene Polymorphism Moderates the Therapeutic Response to Extended-Release Buprenorphine in Opioid Use Disorder.

The international journal of neuropsychopharmacology
2021-02-01 | Journal article
DOI: 10.1093/ijnp/pyaa069
PMID: 32920647
PMC: PMC7883889
Source: Self-asserted source
Emily Hartwell

Systematic review and meta‐analysis of the moderating effect of rs1799971 in OPRM1, the mu‐opioid receptor gene, on response to naltrexone treatment of alcohol use disorder

Addiction
2020-08 | Journal article
DOI: 10.1111/add.14975
Contributors: Emily E. Hartwell; Richard Feinn; Paige E. Morris; Joel Gelernter; John Krystal; Albert J. Arias; Michaela Hoffman; Ismene Petrakis; Ralitza Gueorguieva; Joseph P. Schacht et al.
Source: check_circle
Crossref

Survey of Addiction Specialists' Use of Medications to Treat Alcohol Use Disorder.

Frontiers in psychiatry
2020-02-14 | Journal article
DOI: 10.3389/fpsyt.2020.00047
PMID: 32116860
PMC: PMC7034336
Source: Self-asserted source
Emily Hartwell

Convergence between the Penn Alcohol Craving Scale and diagnostic interview for the assessment of alcohol craving.

Addictive behaviors reports
2019-06-18 | Journal article
DOI: 10.1016/j.abrep.2019.100198
PMID: 31304230
PMC: PMC6599943
Source: Self-asserted source
Emily Hartwell

Pharmacogenetics of alcohol use disorder treatments: an update.

Expert opinion on drug metabolism & toxicology
2019-06-11 | Journal article
DOI: 10.1080/17425255.2019.1628218
PMID: 31162983
PMC: PMC6614002
Source: Self-asserted source
Emily Hartwell

A meta-analysis of the efficacy of gabapentin for treating alcohol use disorder.

Addiction (Abingdon, England)
2019-06-05 | Journal article
DOI: 10.1111/add.14655
PMID: 31077485
PMC: PMC6682454
Source: Self-asserted source
Emily Hartwell

Neuroimaging findings from an experimental pharmacology trial of naltrexone in heavy drinkers of East Asian descent.

Drug and alcohol dependence
2019-05-09 | Journal article
DOI: 10.1016/j.drugalcdep.2019.02.028
PMID: 31160146
PMC: PMC6760244
Source: Self-asserted source
Emily Hartwell

State-of-the-art behavioral and pharmacological treatments for alcohol use disorder.

The American journal of drug and alcohol abuse
2018-10-29 | Journal article
DOI: 10.1080/00952990.2018.1528265
PMID: 30373394
PMC: PMC6430676
Source: Self-asserted source
Emily Hartwell

Craving as a DSM-5 Symptom of Alcohol Use Disorder in Non-Treatment Seekers

Alcohol and Alcoholism
2018-05-01 | Journal article
DOI: 10.1093/alcalc/agx088
Contributors: Emily E Hartwell; Lara A Ray
Source: check_circle
Crossref

Relationship between tonic and phasic craving for alcohol.

Addictive behaviors reports
2018-03-12 | Journal article
DOI: 10.1016/j.abrep.2018.03.001
PMID: 29892699
PMC: PMC5993886
Source: Self-asserted source
Emily Hartwell

Pharmacogenetic Effects of Naltrexone in Individuals of East Asian Descent: Human Laboratory Findings from a Randomized Trial.

Alcoholism, clinical and experimental research
2018-02-01 | Journal article
DOI: 10.1111/acer.13586
PMID: 29265379
PMC: PMC6086578
Source: Self-asserted source
Emily Hartwell

Differences between treatment-seeking and non-treatment-seeking participants in medication studies for alcoholism: do they matter?

The American journal of drug and alcohol abuse
2017-04-20 | Journal article
DOI: 10.1080/00952990.2017.1312423
PMID: 28426264
PMC: PMC6159933
Source: Self-asserted source
Emily Hartwell

Sex Differences in the Association Between Internalizing Symptoms and Craving in Methamphetamine Users.

Journal of addiction medicine
2016-11-01 | Journal article
DOI: 10.1097/adm.0000000000000250
PMID: 27504928
PMC: PMC5083163
Source: Self-asserted source
Emily Hartwell

Mindfulness Based Relapse Prevention for Stimulant Dependent Adults: A Pilot Randomized Clinical Trial.

Mindfulness
2016-08-04 | Journal article
DOI: 10.1007/s12671-016-0586-9
PMID: 28191264
PMC: PMC5300086
Source: Self-asserted source
Emily Hartwell

The Association of Alcohol Severity and Sleep Quality in Problem Drinkers.

Alcohol and alcoholism (Oxford, Oxfordshire)
2015-05-27 | Journal article
DOI: 10.1093/alcalc/agv046
PMID: 26018218
PMC: PMC4537520
Source: Self-asserted source
Emily Hartwell

Combined varenicline and naltrexone treatment reduces smoking topography intensity in heavy-drinking smokers.

Pharmacology, biochemistry, and behavior
2015-04-28 | Journal article
DOI: 10.1016/j.pbb.2015.04.013
PMID: 25933795
PMC: PMC4457679
Source: Self-asserted source
Emily Hartwell

The relationship between methamphetamine and alcohol use in a community sample of methamphetamine users.

Drug and alcohol dependence
2014-06-17 | Journal article
DOI: 10.1016/j.drugalcdep.2014.06.004
PMID: 24975477
PMC: PMC4157644
Source: Self-asserted source
Emily Hartwell

Sleep disturbances and pain among individuals with prescription opioid dependence.

Addictive behaviors
2014-06-02 | Journal article
DOI: 10.1016/j.addbeh.2014.05.025
PMID: 24999989
PMC: PMC4324972
Source: Self-asserted source
Emily Hartwell

Substance use disorders and PTSD: an exploratory study of treatment preferences among military veterans.

Addictive behaviors
2013-10-05 | Journal article
DOI: 10.1016/j.addbeh.2013.09.017
PMID: 24199930
PMC: PMC3855915
Source: Self-asserted source
Emily Hartwell

Craving and subjective responses to alcohol administration: validation of the desires for alcohol questionnaire in the human laboratory.

Journal of studies on alcohol and drugs
2013-09-01 | Journal article
DOI: 10.15288/jsad.2013.74.797
PMID: 23948540
PMC: PMC3749322
Source: Self-asserted source
Emily Hartwell

Sex moderates stress reactivity in heavy drinkers.

Addictive behaviors
2013-06-29 | Journal article
DOI: 10.1016/j.addbeh.2013.06.016
PMID: 23899426
Source: Self-asserted source
Emily Hartwell

Peer review (4 reviews for 4 publications/grants)

Review activity for Molecular psychiatry. (1)
Review activity for Nature communications (1)
Review activity for Neuropsychopharmacology. (1)
Review activity for PloS one. (1)
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