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Keywords

RNA biology, RNA localisation, Neurobiology, Neurodegenerative disease, Virology

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United Kingdom

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Education and qualifications (3)

University of Oxford: Oxford, Oxfordshire, GB

2017 to 2022 | DPhil in Biochemistry (Department of Biochemistry)
Education
Source: Self-asserted source
Jeffrey Y. Lee

University of Cambridge: Cambridge, Cambridgeshire, GB

2016 to 2017 | MPhil Biological Sciences (Biochemistry)
Education
Source: Self-asserted source
Jeffrey Y. Lee

Imperial College London: London, London, GB

2013 to 2016 | BSc Biochemistry (Life Sciences)
Education
Source: Self-asserted source
Jeffrey Y. Lee

Works (15)

Imp/IGF2BP and Syp/SYNCRIP temporal RNA interactomes uncover combinatorial networks of regulators of Drosophila brain development

Science Advances
2025-02-07 | Journal article | Author
DOI: 10.1126/sciadv.adr6682
Contributors: Jeffrey Y. Lee; Niles Huang; Tamsin J Samuels; Ilan Davis
Source: check_circle
AAAS - Science
grade
Preferred source (of 2)‎

Optimization of hybridization chain reaction for imaging single RNA molecules in <i>Drosophila</i> larvae

Fly
2024-12-31 | Journal article
DOI: 10.1080/19336934.2024.2409968
Part of ISSN: 1933-6934
Part of ISSN: 1933-6942
Contributors: Julia Olivares-Abril; Jana Joha; Jeffrey Y. Lee; Ilan Davis
Source: Self-asserted source
Jeffrey Y. Lee

Murine glial protrusion transcripts predict localized Drosophila glial mRNAs involved in plasticity

Journal of Cell Biology
2024-10-07 | Journal article
DOI: 10.1083/jcb.202306152
Contributors: Jeffrey Y. Lee; Dalia S. Gala; Maria Kiourlappou; Julia Olivares-Abril; Jana Joha; Joshua S. Titlow; Rita O. Teodoro; Ilan Davis
Source: check_circle
Crossref

Imp and Sypin vivotemporal RNA interactomes uncover networks of temporal regulators ofDrosophilabrain development

2024-06-30 | Preprint
DOI: 10.1101/2024.06.30.600407
Contributors: Jeffrey Y Lee; Niles Huang; Tamsin J Samuels; Ilan Davis
Source: check_circle
Crossref

Systematic analysis of YFP traps reveals common mRNA/protein discordance in neural tissues

Journal of Cell Biology
2023-06-05 | Journal article
DOI: 10.1083/jcb.202205129
Contributors: Joshua S. Titlow; Maria Kiourlappou; Ana Palanca; Jeffrey Y. Lee; Dalia S. Gala; Darragh Ennis; Joyce J.S. Yu; Florence L. Young; David Miguel Susano Pinto; Sam Garforth et al.
Source: check_circle
Crossref

Mammalian glial protrusion transcriptomes predict localization ofDrosophilaglial transcripts required for synaptic plasticity

2022-12-01 | Preprint
DOI: 10.1101/2022.11.30.518536
Contributors: Dalia S. Gala; Jeffrey Y. Lee; Maria Kiourlappou; Joshua S. Titlow; Rita O. Teodoro; Ilan Davis
Source: check_circle
Crossref

Systematic analysis of YFP gene traps reveals common discordance between mRNA and protein across the nervous system

2022-03-21 | Preprint
DOI: 10.1101/2022.03.21.485142
Contributors: Joshua S Titlow; Maria Kiourlappou; Ana Palanca; Jeffrey Y Lee; Dalia S Gala; Darragh Ennis; Joyce J S Yu; Florence L Young; David Miguel Susano Pinto; Sam Garforth et al.
Source: check_circle
Crossref

Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences

eLife
2022-01-20 | Journal article
DOI: 10.7554/elife.74153
Part of ISSN: 2050-084X
Source: Self-asserted source
Jeffrey Y. Lee
grade
Preferred source (of 2)‎

The microglial P2Y6 receptor mediates neuronal loss and memory deficits in neurodegeneration

Cell Reports
2021-12 | Journal article
DOI: 10.1016/j.celrep.2021.110148
Part of ISSN: 2211-1247
Source: Self-asserted source
Jeffrey Y. Lee

A prenylated dsRNA sensor protects against severe COVID-19

Science
2021-10-29 | Journal article
DOI: 10.1126/science.abj3624
Part of ISSN: 0036-8075
Part of ISSN: 1095-9203
Source: Self-asserted source
Jeffrey Y. Lee

Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection

Molecular Cell
2021-07 | Journal article
DOI: 10.1016/j.molcel.2021.05.023
Part of ISSN: 1097-2765
Source: Self-asserted source
Jeffrey Y. Lee

Absolute quantitation of individual SARS-CoV-2 RNA molecules: a new paradigm for infection dynamics and variant differences

2021-06-29 | Preprint
DOI: 10.1101/2021.06.29.450133
Contributors: Jeffrey Y Lee; Peter AC Wing; Dalia S Gala; Marko Noerenberg; Aino I Järvelin; Josh Titlow; Xiaodong Zhuang; Natasha Palmalux; Louisa Iselin; Mary Kay Thompson et al.
Source: check_circle
Crossref

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

Cell Reports
2021-04 | Journal article
DOI: 10.1016/j.celrep.2021.109020
Part of ISSN: 2211-1247
Source: Self-asserted source
Jeffrey Y. Lee
grade
Preferred source (of 2)‎

Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation.

Biology open
2020-03-23 | Journal article
DOI: 10.1242/bio.049684
PMID: 32205310
Source: Self-asserted source
Jeffrey Y. Lee
grade
Preferred source (of 2)‎

Glucocorticoids activate a synapse weakening pathway culminating in tau phosphorylation in the hippocampus.

Pharmacological research
2017-04-14 | Journal article
DOI: 10.1016/j.phrs.2017.04.015
PMID: 28416463
Source: Self-asserted source
Jeffrey Y. Lee
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