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Scopus Author ID: 57130964600

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Employment (1)

University of Eastern Finland: Kuopio, FI

2020-05 to present | Postdoctoral Researcher (A.I.Viratnen Institute)
Employment
Source: Self-asserted source
0000-0002-5211-1007

Education and qualifications (3)

University of Eastern Finland: Kuopio, FI

2020-04-04 | PhD student (Department of Biomedicine)
Qualification
Source: Self-asserted source
0000-0002-5211-1007

Uppsala University: Uppsala, SE

2012-08-31 | M.Sc Applied Biotechnology
Education
Source: Self-asserted source
0000-0002-5211-1007

Anna University Chennai: Chennai, Tamil Nadu, IN

2006-08-01 to 2010-05-30
Qualification
Source: Self-asserted source
0000-0002-5211-1007

Professional activities (2)

European Atherosclerosis Society: Gothenburg, SE

Young Investigator Award (EAS 2021)
Distinction
Source: Self-asserted source
0000-0002-5211-1007

University of Eastern Finland: Kuopio, FI

2020 | Best PhD thesis
Distinction
Source: Self-asserted source
0000-0002-5211-1007

Funding (7)

Adipose tissue exposed to high fat diet affects extracellular matrix genes in the mesenchymal stem cell population

Grant
Ella and Georg Ehrnrooth Foundation (Helsinki, FI)
URL: https://www.ellageorg.fi/en/grant-information/grants-awarded
Source: Self-asserted source
0000-0002-5211-1007

Adipose tissue exposed to high fat diet affects extracellular matrix genes in the mesenchymal stem cell population

Grant
Sydantutkimussaatio (Helsinki, FI)
Source: Self-asserted source
0000-0002-5211-1007

Extracellular vesicles as carriers of hyaluronan and their role as novel biomarkers

Grant
Centre for International Mobility (Helsinki, FI)
Source: Self-asserted source
0000-0002-5211-1007

Extracellular vesicles as carriers of hyaluronan and their role as novel biomarkers

Grant
Otto A. Malm Lahjoitusrahasto (Helsinki, FI)
URL: https://en.ottomalm.fi/stipends-granted-2014
Source: Self-asserted source
0000-0002-5211-1007

Extracellular vesicles as carriers of hyaluronan and their role as novel biomarkers

Grant
K. Albin Johanssons Stiftelse (Helsinki, FI)
Source: Self-asserted source
0000-0002-5211-1007

Extracellular vesicles as carriers of hyaluronan and their role as novel biomarkers

Grant
Pohjois-Savon Syöpäyhdistys (Kuopio, FI)
Source: Self-asserted source
0000-0002-5211-1007

Extracellular vesicles as carriers of hyaluronan and their role as novel biomarkers

Grant
Paavo Koistisen Saatio (Kuopio, FI)
Source: Self-asserted source
0000-0002-5211-1007

Works (15)

Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease

eBioMedicine
2024-08 | Journal article
DOI: 10.1016/j.ebiom.2024.105232
Contributors: Seung Hyuk T. Lee; Kristina M. Garske; Uma Thanigai Arasu; Asha Kar; Zong Miao; Marcus Alvarez; Amogha Koka; Nicholas Darci-Maher; Jihane N. Benhammou; David Z. Pan et al.
Source: check_circle
Crossref

Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis

Circulation Research
2024-05-24 | Journal article
DOI: 10.1161/CIRCRESAHA.123.323184
Contributors: Giuseppe Mocci; Katyayani Sukhavasi; Tiit Örd; Sean Bankier; Prosanta Singha; Uma Thanigai Arasu; Olayinka Oluwasegun Agbabiaje; Petri Mäkinen; Lijiang Ma; Chani J. Hodonsky et al.
Source: check_circle
Crossref

Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells

Redox Biology
2024-02 | Journal article
DOI: 10.1016/j.redox.2024.103031
Part of ISSN: 2213-2317
Contributors: Ashik Jawahar Deen; Simone Adinolfi; Jouni Härkönen; Tommi Patinen; Xiaonan Liu; Tuomo Laitinen; Piia Takabe; Kirsi Kainulainen; Sanna Pasonen-Seppänen; Lisa M. Gawriyski et al.
Source: Self-asserted source
0000-0002-5211-1007

Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease

eBioMedicine
2023-06 | Journal article
DOI: 10.1016/j.ebiom.2023.104620
Part of ISSN: 2352-3964
Contributors: Nicholas Darci-Maher; Marcus Alvarez; Uma Thanigai Arasu; Ilakya Selvarajan; Seung Hyuk Tony Lee; David Z. Pan; Zong Miao; Sankha Subhra Das; Dorota Kaminska; Tiit Örd et al.
Source: Self-asserted source
0000-0002-5211-1007

Exploring the genetic basis of coronary artery disease using functional genomics

Atherosclerosis
2023-02 | Review
DOI: 10.1016/j.atherosclerosis.2023.01.019
Part of ISSN: 0021-9150
Contributors: Maykel López Rodríguez; Uma Thanigai Arasu; Minna U Kaikkonen
Source: Self-asserted source
0000-0002-5211-1007

HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells

Cellular and Molecular Life Sciences
2020-10-09 | Journal article
DOI: 10.1007/s00018-019-03399-5
Contributors: Uma Thanigai Arasu; Ashik Jawahar Deen; Sanna Pasonen-Seppänen; Sami Heikkinen; Maciej Lalowski; Riikka Kärnä; Kai Härkönen; Petri Mäkinen; Elisa Lázaro-Ibáñez; Pia R-M Siljander et al.
Source: check_circle
Crossref

CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells

Cells
2019-03-22 | Journal article
DOI: 10.3390/cells8030276
Part of ISSN: 2073-4409
Source: Self-asserted source
0000-0002-5211-1007
grade
Preferred source (of 2)‎

Correlative light and electron microscopy is a powerful tool to study interactions of extracellular vesicles with recipient cells

Experimental Cell Research
2019-03-15 | Journal article
DOI: 10.1016/j.yexcr.2019.02.004
Part of ISSN: 0014-4827
Source: Self-asserted source
0000-0002-5211-1007

Extracellular vesicles are integral and functional components of the extracellular matrix

Matrix Biology
2019-01 | Journal article
DOI: 10.1016/j.matbio.2017.10.003
Contributors: Kirsi Rilla; Anne-Mari Mustonen; Uma Thanigai Arasu; Kai Härkönen; Johanna Matilainen; Petteri Nieminen
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2)

Matrix Biology
2018 | Journal article
DOI: 10.1016/j.matbio.2018.10.004
EID:

2-s2.0-85056995641
Contributors: Melero-Fernandez de Mera, R.M.; Arasu, U.T.; Kärnä, R.; Oikari, S.; Rilla, K.; Vigetti, D.; Passi, A.; Heldin, P.; Tammi, M.I.; Deen, A.J.
Source: Self-asserted source
0000-0002-5211-1007 via Scopus - Elsevier

EMT induced by EGF and wounding activates hyaluronan synthesis machinery and EV shedding in rat primary mesothelial cells

Matrix Biology
2017 | Journal article
DOI: 10.1016/j.matbio.2016.12.007
EID:

2-s2.0-85008465232
Contributors: Koistinen, V.; Härkönen, K.; Kärnä, R.; Arasu, U.T.; Oikari, S.; Rilla, K.
Source: Self-asserted source
0000-0002-5211-1007 via Scopus - Elsevier

Human mesenchymal stem cells secrete hyaluronan-coated extracellular vesicles

Matrix Biology
2017 | Journal article
DOI: 10.1016/j.matbio.2017.05.001
EID:

2-s2.0-85019152104
Contributors: Arasu, U.T.; Kärnä, R.; Härkönen, K.; Oikari, S.; Koistinen, A.; Kröger, H.; Qu, C.; Lammi, M.J.; Rilla, K.
Source: Self-asserted source
0000-0002-5211-1007 via Scopus - Elsevier

Metastatic state of parent cells influences the uptake and functionality of prostate cancer cell-derived extracellular vesicles

Journal of Extracellular Vesicles
2017 | Journal article
DOI: 10.1080/20013078.2017.1354645
EID:

2-s2.0-85041747304
Contributors: Lázaro-Ibáñez, E.; Neuvonen, M.; Takatalo, M.; Thanigai Arasu, U.; Capasso, C.; Cerullo, V.; Rhim, J.S.; Rilla, K.; Yliperttula, M.; Siljander, P.R.-M.
Source: Self-asserted source
0000-0002-5211-1007 via Scopus - Elsevier

UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression

Cellular and Molecular Life Sciences
2016 | Journal article
DOI: 10.1007/s00018-016-2158-5
EID:

2-s2.0-84958745959
Contributors: Deen, A.J.; Arasu, U.T.; Pasonen-Seppänen, S.; Hassinen, A.; Takabe, P.; Wojciechowski, S.; Kärnä, R.; Rilla, K.; Kellokumpu, S.; Tammi, R. et al.
Source: Self-asserted source
0000-0002-5211-1007 via Scopus - Elsevier

Identification and expression of stressosomal proteins in mycobacterium marinum under various growth and stress conditions

FEMS Microbiology Letters
2013 | Journal article
DOI: 10.1111/1574-6968.12118
EID:

2-s2.0-84876847574
Contributors: Pettersson, B.M.F.; Nitharwal, R.G.; Das, S.; Behra, K.P.R.; Benedik, E.; Arasu, U.T.; Islam, N.M.; Dasgupta, S.; Bhattacharya, A.; Kirsebom, L.A.
Source: Self-asserted source
0000-0002-5211-1007 via Scopus - Elsevier
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