Personal information

computational epidemiology, infectious disease modeling, emerging infectious diseases, antimicrobial resistance
Switzerland

Biography

PD Dr. Christian L. Althaus is a computational epidemiologist and head of the Interfaculty Platform for Data and Computational Science (INPUT) at the Institute of Social and Preventive Medicine (ISPM) at the University of Bern at the University of Bern, Switzerland. He is also a member of the directorate of ISPM.

After studying biology at ETH Zurich (Switzerland), Dr. Althaus received his doctorate in theoretical biology at Utrecht University (The Netherlands). In 2017, he qualified as a university lecturer at the University of Bern medical faculty in the field of infectious disease epidemiology. He uses mathematical and computational modeling in combination with data analyses to investigate how the health of populations and the spread of infectious diseases are affected by environmental changes and public health interventions. Dr. Althaus is an expert for emerging infectious diseases and has made major contributions to the better understanding of the transmission dynamics of Ebola, MERS, and COVID-19. He is a member of the Multidisciplinary Center for Infectious Diseases (MCID) and the Bern Data Science Initiative (BeDSI) at the University of Bern, and served as a member of the Swiss National COVID-19 Science Task Force.

Activities

Employment (1)

Universitat Bern: Bern, Bern, CH

Employment
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University of Bern

Education and qualifications (3)

Utrecht University: Utrecht, NL

2005 to 2009 | Ph.D. (Theoretical Biology)
Education
Source: Self-asserted source
PD Dr. Christian L. Althaus

ETH Zurich: Zurich, CH

1998 to 2004 | Dipl. Natw. ETH (Biology)
Education
Source: Self-asserted source
PD Dr. Christian L. Althaus

Humboldt-Universität zu Berlin: Berlin, DE

2002 to 2002
Education
Source: Self-asserted source
PD Dr. Christian L. Althaus

Funding (4)

What will be the impact of human papillomavirus (HPV) vaccination on HPV-associated cancers in Switzerland? A mathematical modelling study

2015-05 to 2017-10 | Grant
Swiss Cancer Research (Bern, CH)
Source: Self-asserted source
PD Dr. Christian L. Althaus

Exploring response surfaces and synergistic interactions of antibiotic combination treatment for Neisseria gonorrhoeae

2014-01 to 2016-12 | Grant
SystemsX.ch (The Swiss Initiative in Systems Biology) (Zurich, CH)
Source: Self-asserted source
PD Dr. Christian L. Althaus

Rapid diagnosis of antibiotic resistance in gonorrhoea: RADAR-Go

2014-01 to 2016-12 | Grant
SwissTransMed project (Platforms for Translational Research in Medicine) (Bern, CH)
Source: Self-asserted source
PD Dr. Christian L. Althaus

Acute and chronic dynamics of HIV and HCV infections, within-host evolution and epidemiological outcomes

2011-10 to 2014-11 | Grant
Swiss National Science Foundation (SNSF) (Berne, CH)
GRANT_NUMBER: 136737
Source: Self-asserted source
PD Dr. Christian L. Althaus

Works (50 of 69)

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Retrospective modelling of the disease and mortality burden of the 1918–1920 influenza pandemic in Zurich, Switzerland

Epidemics
2025-03 | Journal article
Contributors: Ella Ziegler; Katarina L. Matthes; Peter W. Middelkamp; Verena J. Schuenemann; Christian L. Althaus; Frank Rühli; Kaspar Staub
Source: check_circle
Crossref

EstimatingReand overdispersion in secondary cases from the size of identical sequence clusters of SARS-CoV-2

2024-05-27 | Preprint
Contributors: Emma B. Hodcroft; Martin S. Wohlfender; Richard A. Neher; Julien Riou; Christian L. Althaus
Source: check_circle
Crossref

(Re-)modelling of the disease and mortality burden of the 1918-1920 influenza pandemic in Zurich, Switzerland

2024-03-15 | Preprint
Contributors: Ella Ziegler; Katarina L. Matthes; Peter W. Middelkamp; Verena Schünemann; Christian L. Althaus; Frank Rühli; Kaspar Staub
Source: check_circle
Crossref

Social contact patterns following the COVID-19 pandemic: a snapshot of post-pandemic behaviour from the CoMix study

2023-08-29 | Preprint
Contributors: Christopher I Jarvis; Pietro Coletti; Jantien A Backer; James D Munday; Christel Faes; Philippe Beutels; Christian L. Althaus; Nicola Low; Jacco Wallinga; Niel Hens et al.
Source: check_circle
Crossref

Socio-demographic characteristics associated with COVID-19 vaccination uptake in Switzerland: longitudinal analysis of the CoMix study

2023-03-20 | Preprint
Contributors: Martina L Reichmuth; Leonie Heron; Julien Riou; André Moser; Anthony Hauser; Nicola Low; Christian L Althaus
Source: check_circle
Crossref

Importation of Alpha and Delta variants during the SARS-CoV-2 epidemic in Switzerland: phylogenetic analysis and intervention scenarios

2023-03-17 | Preprint
Contributors: Martina L Reichmuth; Emma B Hodcroft; Christian L Althaus
Source: check_circle
Crossref

Direct and indirect effects of the COVID-19 pandemic on mortality in Switzerland

Nature Communications
2023-01-06 | Journal article
Contributors: Julien Riou; Anthony Hauser; Anna Fesser; Christian L. Althaus; Matthias Egger; Garyfallos Konstantinoudis
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Crossref

EpiLPS: A fast and flexible Bayesian tool for estimation of the time-varying reproduction number

PLOS Computational Biology
2022-10-10 | Journal article
Contributors: Oswaldo Gressani; Claudio José Struchiner; Jacco Wallinga; Christian L. Althaus; Niel Hens; Christel Faes
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Crossref

Direct and indirect effects of the COVID-19 pandemic on mortality in Switzerland: A population-based study

2022-08-06 | Preprint
Contributors: Julien Riou; Anthony Hauser; Anna Fesser; Christian L. Althaus; Matthias Egger; Garyfallos Konstantinoudis
Source: check_circle
Crossref

Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

Nature
2022-03-24 | Journal article
Contributors: Raquel Viana; Sikhulile Moyo; Daniel G. Amoako; Houriiyah Tegally; Cathrine Scheepers; Christian L. Althaus; Ugochukwu J. Anyaneji; Phillip A. Bester; Maciej F. Boni; Mohammed Chand et al.
Source: check_circle
Crossref

Replacement of the Gamma by the Delta variant in Brazil: impact of lineage displacement on the ongoing pandemic

2021-12-29 | Preprint
Contributors: Marta Giovanetti; Vagner Fonseca; Eduan Wilkinson; Houriiyah Tegally; Emmanuel James San; Christian L. Althaus; Joilson Xavier; Svetoslav Nanev Slavov; Vincent Louis Viala; Alex Ranieri Jerônimo Lima et al.
Source: check_circle
Crossref

Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

2021-12-21 | Preprint
Contributors: Raquel Viana; Sikhulile Moyo; Daniel G Amoako; Houriiyah Tegally; Cathrine Scheepers; Christian L Althaus; Ugochukwu J Anyaneji; Phillip A Bester; Maciej F Boni; Mohammed Chand et al.
Source: check_circle
Crossref

Estimating the effects of accelerated partner therapy (APT) on reinfection of index cases with chlamydia: a mathematical modelling study

2021-08-13 | Other
Contributors: Christian L. Althaus; Claudia S. Estcourt; Nicola Low
Source: check_circle
Crossref

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020

Nature
2021-07-29 | Journal article
Contributors: Emma B. Hodcroft; Moira Zuber; Sarah Nadeau; Timothy G. Vaughan; Katharine H. D. Crawford; Christian L. Althaus; Martina L. Reichmuth; John E. Bowen; Alexandra C. Walls; Davide Corti et al.
Source: check_circle
Crossref

The cost-effectiveness of accelerated partner therapy (APT) compared to standard contact tracing for people with chlamydia: an economic evaluation based on the LUSTRUM population-based chlamydia transmission model

2021-07-29 | Other
Contributors: EV Williams; Ogwulu CB Okeke; CS Estcourt; AR Howarth; A Copas; N Low; C Althaus; F Mapp; Owusu M Woode; M Symonds et al.
Source: check_circle
Crossref

A tale of two variants: Spread of SARS-CoV-2 variants Alpha in Geneva, Switzerland, and Beta in South Africa

2021-06-15 | Other
Contributors: Christian L. Althaus; Stephanie Baggio; Martina L. Reichmuth; Emma B. Hodcroft; Julien Riou; Richard A. Neher; Frédérique Jacquerioz; Hervé Spechbach; Julien Salamun; Pauline Vetter et al.
Source: check_circle
Crossref

Investigating the effects of accelerated partner therapy (APT) on chlamydia transmission in Britain: a mathematical modelling study

2020-12-08 | Other
Contributors: Christian L Althaus; Catherine H Mercer; Jackie A Cassell; Claudia S Estcourt; Nicola Low
Source: check_circle
Crossref

Emergence and spread of a SARS-CoV-2 variant through Europe in the summer of 2020

2020-10-28 | Other
Contributors: Emma B. Hodcroft; Moira Zuber; Sarah Nadeau; Timothy G. Vaughan; Katharine H. D. Crawford; Christian L. Althaus; Martina L. Reichmuth; John E. Bowen; Alexandra C. Walls; Davide Corti et al.
Source: check_circle
Crossref

Rise and fall of the new variant ofChlamydia trachomatisin Sweden: mathematical modelling study

Sexually Transmitted Infections
2020-08 | Journal article
Contributors: Joost H Smid; Christian L Althaus; Nicola Low; Magnus Unemo; Bjőrn Herrmann
Source: check_circle
Crossref

Time is of the essence: containment of the SARS-CoV-2 epidemic in Switzerland from February to May 2020

2020-07-25 | Other
Contributors: Christian L. Althaus; Daniel Probst; Anthony Hauser; Julien Riou
Source: check_circle
Crossref

Pattern of early human-to-human transmission of Wuhan 2019-nCoV

2020-01-24 | Preprint
Contributors: Julien Riou; Christian L. Althaus
Source: check_circle
Crossref

Gini coefficients for measuring the distribution of sexually transmitted infections among individuals with different levels of sexual activity

PeerJ
2020-01-20 | Journal article
Contributors: Sandro Gsteiger; Nicola Low; Pam Sonnenberg; Catherine H. Mercer; Christian L. Althaus
Source: check_circle
Crossref

Impact and cost-effectiveness of nonavalent human papillomavirus vaccination in Switzerland: insights from a dynamic transmission model

2019-12-11 | Other
Contributors: Maurane Riesen; Johannes A. Bogaards; Nicola Low; Christian L. Althaus
Source: check_circle
Crossref

Impact of age-specific immunity on the timing and burden of the next Zika virus outbreak

2019-06-07 | Other
Contributors: Michel J. Counotte; Christian L. Althaus; Nicola Low; Julien Riou
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Crossref

Discrepancies between observed data and predictions from mathematical modelling of the impact of screening interventions on Chlamydia trachomatis prevalence

Scientific Reports
2019-05-17 | Journal article
Contributors: Joost Smid; Christian L. Althaus; Nicola Low
Source: check_circle
Crossref

The use of mathematical modeling studies for evidence synthesis and guideline development: A glossary

Research Synthesis Methods
2019-03 | Journal article
Contributors: Teegwendé V. Porgo; Susan L. Norris; Georgia Salanti; Leigh F. Johnson; Julie A. Simpson; Nicola Low; Matthias Egger; Christian L. Althaus
Source: check_circle
Crossref

The rise and fall of the new variant of Chlamydia trachomatis in Sweden: mathematical modelling study

2019-03-08 | Other
Contributors: Joost Smid; Christian L. Althaus; Nicola Low; Magnus Unemo; Björn Herrmann
Source: check_circle
Crossref

Gini coefficients for measuring the distribution of sexually transmitted infections among individuals with different levels of sexual activity

2018-10-11 | Other
Contributors: Sandro Gsteiger; Nicola Low; Pam Sonnenberg; Catherine H Mercer; Christian L Althaus
Source: check_circle
Crossref

Exploring variation in human papillomavirus vaccination uptake in Switzerland: a multilevel spatial analysis of a national vaccination coverage survey

BMJ Open
2018-05 | Journal article
Contributors: Maurane Riesen; Garyfallos Konstantinoudis; Phung Lang; Nicola Low; Christoph Hatz; Mirjam Maeusezahl; Anne Spaar; Marc Bühlmann; Ben D Spycher; Christian L Althaus
Source: check_circle
Crossref

De novo mutations drive the spread of macrolide-resistant Mycoplasma genitalium: a mathematical modelling study

2018-05-24 | Other
Contributors: Dominique Cadosch; Victor Garcia; Christian L. Althaus; Jørgen Skov Jensen; Nicola Low
Source: check_circle
Crossref

Transmission of and susceptibility to seasonal influenza in Switzerland from 2003–2015

2018-01-31 | Other
Contributors: Jon Brugger; Christian L. Althaus
Source: check_circle
Crossref

Exploring variation in human papillomavirus vaccination uptake: multi-level spatial analysis

2017-11-03 | Other
Contributors: Maurane Riesen; Garyfallos Konstantinoudis; Phung Lang; Nicola Low; Christoph Hatz; Mirjam Maeusezahl; Anne Spaar; Marc Bühlmann; Ben D. Spycher; Christian L. Althaus
Source: check_circle
Crossref

Fitness cost and benefit of antimicrobial resistance in Neisseria gonorrhoeae: Multidisciplinary approaches are needed

PLOS Medicine
2017-10-31 | Journal article
Contributors: Magnus Unemo; Christian L. Althaus
Source: check_circle
Crossref

Modeling the consequences of regional heterogeneity in human papillomavirus (HPV) vaccination uptake on transmission in Switzerland

2017-04-10 | Preprint
Contributors: Maurane Riesen; Victor Garcia; Nicola Low; Christian L. Althaus
Source: check_circle
Crossref

Of mice, macaques and men: scaling of virus dynamics and immune responses.

2015 | Journal article
Contributors: Althaus CL
Source: Self-asserted source
PD Dr. Christian L. Althaus via Europe PubMed Central

The role of superspreading in Middle East respiratory syndrome coronavirus (MERS-CoV) transmission.

2015 | Journal article
Contributors: Kucharski AJ; Althaus CL
Source: Self-asserted source
PD Dr. Christian L. Althaus via Europe PubMed Central

How sex acts scale with the number of sex partners: evidence from Chlamydia trachomatis data and implications for control

2015-10-30 | Other
Contributors: Christian L Althaus; Marc Choisy; Samuel Alizon
Source: check_circle
Crossref

How sex acts scale with the number of sex partners: evidence from Chlamydia trachomatis data and implications for control

2015-10-30 | Other
Contributors: Christian L Althaus; Marc Choisy; Samuel Alizon
Source: check_circle
Crossref

Antibiotic-resistant Neisseria gonorrhoeae spread faster with more treatment, not more sexual partners

2015-10-24 | Other
Contributors: Stephanie M Fingerhuth; Sebastian Bonhoeffer; Nicola Low; Christian L Althaus
Source: check_circle
Crossref

Antibiotic-resistant Neisseria gonorrhoeae spread faster with more treatment, not more sexual partners

2015-10-24 | Other
Contributors: Stephanie M Fingerhuth; Sebastian Bonhoeffer; Nicola Low; Christian L Althaus
Source: check_circle
Crossref

Time-kill curve analysis and pharmacodynamic functions forin vitroevaluation of antimicrobials againstNeisseria gonorrhoeae

2015-10-06 | Preprint
Contributors: Sunniva Foerster; Magnus Unemo; Lucy J. Hathaway; Nicola Low; Christian L. Althaus
Source: check_circle
Crossref

Measles Vaccination Coverage and Cases among Vaccinated Persons.

2015-08 | Journal article
Contributors: Althaus CL; Salathé M
Source: Self-asserted source
PD Dr. Christian L. Althaus via Europe PubMed Central

Ebola virus disease outbreak in Nigeria: Transmission dynamics and rapid control.

2015-06 | Journal article
Contributors: Althaus CL; Low N; Musa EO; Shuaib F; Gsteiger S
Source: Self-asserted source
PD Dr. Christian L. Althaus via Europe PubMed Central

Ebola superspreading.

2015-05 | Journal article
Contributors: Althaus CL
Source: Self-asserted source
PD Dr. Christian L. Althaus via Europe PubMed Central

Estimating the Reproduction Number of Ebola Virus (EBOV) During the 2014 Outbreak in West Africa.

Source: Self-asserted source
PD Dr. Christian L. Althaus via Europe PubMed Central

Quantifying the turnover of transcriptional subclasses of HIV-1-infected cells.

2014-10 | Journal article
Contributors: Althaus CL; Joos B; Perelson AS; Günthard HF
Source: Self-asserted source
PD Dr. Christian L. Althaus via Europe PubMed Central

Reinfection by untreated partners of people treated for Chlamydia trachomatis and Neisseria gonorrhoeae: mathematical modelling study.

2014-05 | Journal article
Contributors: Low N; Heijne JC; Herzog SA; Althaus CL
Source: Self-asserted source
PD Dr. Christian L. Althaus via Europe PubMed Central

Effectiveness and cost-effectiveness of traditional and new partner notification technologies for curable sexually transmitted infections: observational study, systematic reviews and mathematical modelling.

2014-01 | Journal article
Contributors: Althaus CL; Turner KM; Mercer CH; Auguste P; Roberts TE; Bell G; Herzog SA; Cassell JA; Edmunds WJ; White PJ et al.
Source: Self-asserted source
PD Dr. Christian L. Althaus via Europe PubMed Central

Case and partnership reproduction numbers for a curable sexually transmitted infection

Journal of Theoretical Biology
2013 | Journal article
Contributors: Althaus, C.L.; Heijne, J.C.M.; Herzog, S.A.; Kretzschmar, M.; Low, N.
Source: Self-asserted source
PD Dr. Christian L. Althaus via Scopus - Elsevier

Insights into the timing of repeated testing after treatment for chlamydia trachomatis: Data and modelling study

Sexually Transmitted Infections
2013 | Journal article
Contributors: Althaus, C.L.; Heijne, J.C.M.; Herzog, S.A.; Kent, C.K.; Low, N.; Tao, G.
Source: Self-asserted source
PD Dr. Christian L. Althaus via Scopus - Elsevier
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Peer review (3 reviews for 2 publications/grants)

Review activity for BMC medicine (1)
Review activity for Epidemics. (2)