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Bio-carriers, Radiotherapy, Immunotherapy, Radio-protection, Nuclear medicine
China

Biography

Pei Pei, Ph.D., Associate Professor and Master's Supervisor at the School of Basic Medical Sciences, Anhui Medical University, is recognized as a Type-D high-level talent (city-level leading talent) in Hefei. The primary research focus includes the regulation of the tumor microenvironment, neutron, proton, and heavy ion immunotherapy, radiolabeled imaging diagnostics, investigation of potential mechanisms in radiation, as well as radiation protection and toxicology evaluation.

Activities

Employment (1)

Anhui Medical University: Hefei, Anhui, CN

2022-08-11 to present | Professor (Associate) (School of Basic Medical Sciences)
Employment
Source: Self-asserted source
Pei Pei

Education and qualifications (2)

Soochow University: Suzhou, Jiangsu, CN

2019-09-01 to 2022-06-30 | Doctor (School of Radiation Medicine and Protection, State Key Laboratory of Radiation Medicine and Protection)
Education
Source: Self-asserted source
Pei Pei

Hefei University of Technology: Hefei, CN

2016-09-01 to 2019-06-30 | Master
Education
Source: Self-asserted source
Pei Pei

Funding (4)

Ac-225 labeled engineered bacterial outer membrane vesicles for tumor radioimmunotherapy and mechanistic exploration

2024-01 to 2025-12 | Grant
National Natural Science Foundation of China (Beijing, CN)
Source: Self-asserted source
Pei Pei

Exploration of X-ray assisted nanozyme-coated bacteria for regulating tumor microenvironment to enhance radioimmunotherapy and mechanism investigation

2023-09 to 2025-08 | Grant
Anhui Provincial Natural Science Foundation (Hefei, Anhui, CN)
Source: Self-asserted source
Pei Pei

Manganese-doped nanoenzymes effectively modulate the tumor microenvironment to enhance radioimmunotherapy

2023-01 to 2024-12 | Grant
Key Scientific Research Project of Colleges and Universities in Anhui Province of China (Hefei, Anhui, CN)
Source: Self-asserted source
Pei Pei

Radionuclide labeled gold nanoclusters boost effective anti-tumor immunity for augmented radio-immunotherapy of cancer

2020-04 to 2021-03 | Grant
Graduate Research and Innovation Projects of Jiangsu Province (Soochow, CN)
Source: Self-asserted source
Pei Pei

Works (40)

Novel bio-carriers for radionuclide delivery in cancer radiotherapy

Coordination Chemistry Reviews
2025-06 | Journal article
Part of ISSN: 0010-8545
Contributors: Lishan Wang; Qing He; Jianping Man; Yechen Gao; Guangming Zhou; Hongwei Si; Kai Yang; Lin Hu; Pei Pei
Source: Self-asserted source
Pei Pei

Chimeric Antigen Receptor Cells Solid Tumor Immunotherapy Assisted by Biomaterials Tools

ACS Applied Materials & Interfaces
2025-02-19 | Journal article
Contributors: Yujie Song; Yifan Wang; Jianping Man; Yihua Xu; Guangming Zhou; Wenhao Shen; Yu Chao; Kai Yang; Pei Pei; Lin Hu
Source: check_circle
Crossref

Biomaterials to regulate tumor extracellular matrix in immunotherapy

Journal of Controlled Release
2024 | Journal article
EID:

2-s2.0-85205992478

Part of ISSN: 18734995 01683659
Contributors: Zhang, Y.; Dong, X.; Zhang, Y.; Chen, Z.; Zhou, G.; Chen, N.; Shen, W.; Yang, K.; Pei, P.
Source: Self-asserted source
Pei Pei via Scopus - Elsevier
grade
Preferred source (of 2)‎

Engineered bacteria breach tumor physical barriers to enhance radio-immunotherapy

Journal of Controlled Release
2024 | Journal article
EID:

2-s2.0-85200227043

Part of ISSN: 18734995 01683659
Contributors: Zhang, Y.; Liu, Y.; Li, T.; Yang, X.; Lang, S.; Pei, P.; Pei, H.; Chang, L.; Hu, L.; Liu, T. et al.
Source: Self-asserted source
Pei Pei via Scopus - Elsevier
grade
Preferred source (of 2)‎

Surface Engineering on Bacteria for Tumor Immunotherapy: Strategies and Perspectives

Advanced Functional Materials
2024 | Journal article
EID:

2-s2.0-85193282622

Part of ISSN: 16163028 1616301X
Contributors: Fu, L.; He, Q.; Lu, X.; Hu, L.; Qiang, H.; Pei, P.
Source: Self-asserted source
Pei Pei via Scopus - Elsevier
grade
Preferred source (of 2)‎

Two-dimensional nano-biomaterials in regulating the tumor microenvironment for immunotherapy

Nano TransMed
2024 | Journal article
EID:

2-s2.0-85203262408

Part of ISSN: 27906760 27907384
Contributors: Xu, G.; Li, J.; Zhang, S.; Cai, J.; Deng, X.; Wang, Y.; Pei, P.
Source: Self-asserted source
Pei Pei via Scopus - Elsevier
grade
Preferred source (of 2)‎

Advancements in colorectal cancer detection: The role of immuno‐positron emission tomography, immuno‐single‐photon emission computed tomography, and machine learning applications

Journal of Intelligent Medicine
2024-10-28 | Journal article
Part of ISSN: 2837-6749
Part of ISSN: 2837-6757
Contributors: Surui Chen; Xiumin Shi; Shu Liu; Pei Pei; kai yang; Lin Hu
Source: Self-asserted source
Pei Pei

Harnessing Bacterial Membrane Components for Tumor Vaccines: Strategies and Perspectives

Advanced Healthcare Materials
2024-07-04 | Journal article
Contributors: Zhenxin Bai; Xuanyu Wang; Tianming Liang; Guangyu Xu; Jinzhou Cai; Wei Xu; Kai Yang; Lin Hu; Pei Pei
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Biomaterials-mediated radiation-induced diseases treatment and radiation protection

Journal of Controlled Release
2024-06 | Journal article
Part of ISSN: 0168-3659
Contributors: Jianping Man; Yanhua Shen; Yujie Song; Kai Yang; Pei Pei; Lin Hu
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 3)‎

Copper in colorectal cancer: From copper‐related mechanisms to clinical cancer therapies

Clinical and Translational Medicine
2024-06 | Journal article
Part of ISSN: 2001-1326
Part of ISSN: 2001-1326
Contributors: Yuhong Wang; Pei Pei; kai yang; Lingchuan Guo; Yuan Li
Source: Self-asserted source
Pei Pei

Dietary Flavonoid Quercetin Supplement Promotes Antiviral Innate Responses Against Vesicular Stomatitis Virus Infection by Reshaping the Bacteriome and Host Metabolome in Mice

Molecular Nutrition & Food Research
2024-05-16 | Journal article
Part of ISSN: 1613-4125
Part of ISSN: 1613-4133
Contributors: Tingting Li; Jinfeng Zhu; Qifeng Yu; Yinrui Zhu; Chao Wu; Xing Zheng; Nannan Chen; Pei Pei; Kai Yang; Kai Wang et al.
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Radionuclide-Labeled Antisilencing Function 1a Inhibitory Peptides for Tumor Identification and Individualized Therapy

ACS Nano
2024-03-13 | Journal article
Part of ISSN: 1936-0851
Part of ISSN: 1936-086X
Contributors: Xiumin Shi; Teng Liu; Pei Pei; Wenhao Shen; Lin Hu; Ran Zhu; Feng Wang; Chunying Chen; kai yang
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Oxygen‐driven cuproptosis synergizes with radiotherapy to potentiate tumor immunotherapy

Aggregate
2024-01-04 | Journal article
Part of ISSN: 2692-4560
Part of ISSN: 2692-4560
Contributors: Pei Pei; Yuhong Wang; Wenhao Shen; Qing He; Xiangming Han; Chonghai Zhang; Yuyuan Xie; Guangming Zhou; Ye Zhao; Lin Hu et al.
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Translational Study on the Antiviral Effects of Flavonoids Against Vesicular Stomatitis Virus Infection: From in vitro Cell-Based Evidence to in vivo Regulation of Gut Microbiota and Inflammation

SSRN
2023 | Other
EID:

2-s2.0-85174025896

Part of ISSN: 15565068
Contributors: Li, T.; Zhu, J.; Yu, Q.; Zhu, Y.; Wu, C.; Zheng, X.; Chen, N.; Pei, P.; Yang, K.; Wang, K. et al.
Source: Self-asserted source
Pei Pei via Scopus - Elsevier

A Polymeric Hydrogel to Eliminate Programmed Death-Ligand 1 for Enhanced Tumor Radio-Immunotherapy

ACS Nano
2023-12-12 | Journal article
Part of ISSN: 1936-0851
Part of ISSN: 1936-086X
Contributors: Wenhao Shen; Pei Pei; Chonghai Zhang; Junmei Li; Xiangming Han; Teng Liu; Xiumin Shi; Zhiyue Su; Gaohua Han; Lin Hu et al.
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Simultaneous Modulation of Hypoxia And Metabolism in Glioblastoma for Enhanced Radio‐Immunotherapy

Advanced Functional Materials
2023-12-12 | Journal article
Part of ISSN: 1616-301X
Part of ISSN: 1616-3028
Contributors: Yuyuan Xie; Chonghai Zhang; Ye Zhao; Tingting Li; Wenhao Shen; Lin Hu; Kai Yang; Pei Pei; Teng Liu
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Nanozyme‐Coated Bacteria Hitchhike on CD11b<sup>+</sup> Immune Cells to Boost Tumor Radio‐Immunotherapy

Advanced Materials
2023-11-07 | Journal article
Part of ISSN: 0935-9648
Part of ISSN: 1521-4095
Contributors: Hanghang Li; Pei Pei; Qing He; Xuexue Dong; Chonghai Zhang; Wenhao Shen; Hua Chen; Lin Hu; Yugui Tao; kai yang
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Radionuclide‐Labeled Microspheres for Radio‐Immunotherapy of Hepatocellular Carcinoma

Advanced Healthcare Materials
2023-10 | Journal article
Part of ISSN: 2192-2640
Part of ISSN: 2192-2659
Contributors: Sai Yang; Chongjing Mu; Teng Liu; Pei Pei; Wenhao Shen; Yanxiang Zhang; Guanglin Wang; Lei Chen; kai yang
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

The role of bacteria and its derived biomaterials in cancer radiotherapy

Acta Pharmaceutica Sinica B
2023-10 | Journal article
Contributors: Yu Zhang; Ruizhe Huang; Yunchun Jiang; Wenhao Shen; Hailong Pei; Guanglin Wang; Pei Pei; Kai Yang
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Liposome-anchored mesenchymal stem cells for radiation pneumonia/fibrosis treatment

Biomaterials
2023-09 | Journal article
Part of ISSN: 0142-9612
Contributors: Hailin Zhou; Yanxiang Zhang; Pei Pei; Wenhao Shen; Xuan Yi; kai yang
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Radiation‐Induced Immunogenic Cell Death for Cancer Radioimmunotherapy

Small Methods
2023-05 | Journal article
Part of ISSN: 2366-9608
Part of ISSN: 2366-9608
Contributors: Teng Liu; Pei Pei; Wenhao Shen; Lin Hu; kai yang
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Nattokinase-Mediated Regulation of Tumor Physical Microenvironment to Enhance Chemotherapy, Radiotherapy, and CAR-T Therapy of Solid Tumor

ACS Nano
2023-04-25 | Journal article
Part of ISSN: 1936-0851
Part of ISSN: 1936-086X
Contributors: Yanxiang Zhang; Pei Pei; Hailin Zhou; Yuyuan Xie; Sai Yang; Wenhao Shen; Lin Hu; Yujuan Zhang; Teng Liu; kai yang
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Tumor Microenvironment-Responsive BSA Nanocarriers For Combined Chemo/Chemodynamic Cancer Therapy

Research Square
2022 | Other
EID:

2-s2.0-85167244407

Contributors: Zhang, R.; Liu, T.; Li, W.; Ma, Z.; Pei, P.; Zhang, W.; Yang, K.; Tao, Y.
Source: Self-asserted source
Pei Pei via Scopus - Elsevier

Metabolic Homeostasis‐Regulated Nanoparticles for Antibody‐Independent Cancer Radio‐Immunotherapy

Advanced Materials
2022-12 | Journal article
Part of ISSN: 0935-9648
Part of ISSN: 1521-4095
Contributors: Wenhao Shen; Teng Liu; Pei Pei; Junmei Li; Sai Yang; Yanxiang Zhang; Hailin Zhou; Lin Hu; kai yang
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Tumor microenvironment-responsive BSA nanocarriers for combined chemo/chemodynamic cancer therapy

Journal of Nanobiotechnology
2022-12 | Journal article
Part of ISSN: 1477-3155
Contributors: Ruiyi Zhang; Teng Liu; Wanzhen Li; Zhiyuan Ma; Pei Pei; Weiwei Zhang; Kai Yang; Yugui Tao
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Pleiotropic Immunomodulatory Functions of Radioactive Inactivated Bacterial Vectors for Enhanced Cancer Radio-immunotherapy

ACS Nano
2022-07-12 | Journal article
Part of ISSN: 1936-0851
Part of ISSN: 1936-086X
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

131I-αPD-L1 immobilized by bacterial cellulose for enhanced radio-immunotherapy of cancer

Journal of Controlled Release
2022-06 | Journal article
Part of ISSN: 0168-3659
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Combined Prussian Blue Nanozyme Carriers Improve Photodynamic Therapy and Effective Interruption of Tumor Metastasis

International Journal of Nanomedicine
2022-03 | Journal article
Part of ISSN: 1178-2013
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 3)‎

Radioactive nano-oxygen generator enhance anti-tumor radio-immunotherapy by regulating tumor microenvironment and reducing proliferation

Biomaterials
2022-01 | Journal article
Part of ISSN: 0142-9612
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Biocompatible nanomicelles for sensitive detection and photodynamic therapy of early-stage cancer

Biomaterials Science
2021 | Journal article
Part of ISSN: 2047-4830
Part of ISSN: 2047-4849
Contributors: Hailin Zhou; Zhongyuan Qi; Pei Pei; Wenhao Shen; Yanxiang Zhang; kai yang; Liang Sun; Teng Liu
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Biomaterial-mediated internal radioisotope therapy

Materials Horizons
2021 | Journal article
Part of ISSN: 2051-6347
Part of ISSN: 2051-6355
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Versatile labeling of multiple radionuclides onto a nanoscale metal–organic framework for tumor imaging and radioisotope therapy

Biomaterials Science
2021 | Journal article
Part of ISSN: 2047-4830
Part of ISSN: 2047-4849
Contributors: Yugui Tao; Yuanchen Sun; Kexin Shi; Pei Pei; Fei Ge; kai yang; Teng Liu
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Radionuclide labeled gold nanoclusters boost effective anti-tumor immunity for augmented radio-immunotherapy of cancer

Nano Today
2021-06 | Journal article
Part of ISSN: 1748-0132
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 3)‎

A general strategy towards personalized nanovaccines based on fluoropolymers for post-surgical cancer immunotherapy

Nature Nanotechnology
2020-12 | Journal article
Part of ISSN: 1748-3387
Part of ISSN: 1748-3395
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 3)‎

The potential clinical applications of radionuclide labeled/doped gold-based nanomaterials

Radiation Medicine and Protection
2020-12 | Journal article
Part of ISSN: 2666-5557
Contributors: Wenhao Shen; Hailin Zhou; Teng Liu; Pei Pei; Junxing Huang; Xuan Yi; kai yang
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Bi2S3 coated Au nanorods for enhanced photodynamic and photothermal antibacterial activities under NIR light

Chemical Engineering Journal
2020-10 | Journal article
Part of ISSN: 1385-8947
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Rod-based urchin-like hollow microspheres of Bi2S3: Facile synthesis, photo-controlled drug release for photoacoustic imaging and chemo-photothermal therapy of tumor ablation

Biomaterials
2020-04 | Journal article
Part of ISSN: 0142-9612
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Precisely photothermal controlled releasing of antibacterial agent from Bi2S3 hollow microspheres triggered by NIR light for water sterilization

Chemical Engineering Journal
2020-02 | Journal article
Part of ISSN: 1385-8947
Contributors: Wan-Ni Wang; Chen-Yang Zhang; Mao-Feng Zhang; Pei Pei; Wei Zhou; Zheng-Bao Zha; Min Shao; Hai-Sheng Qian
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

ROS-sensitive thioketal-linked polyphosphoester-doxorubicin conjugate for precise phototriggered locoregional chemotherapy

Biomaterials
2019-01 | Journal article
Part of ISSN: 0142-9612
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Encapsulation of cisplatin in a pegylated calcium phosphate nanoparticle (CPNP) for enhanced cytotoxicity to cancerous cells

Journal of Colloid and Interface Science
2017-05 | Journal article
Part of ISSN: 0021-9797
Contributors: Yang Ding; Kang Zhai; Pei Pei; Yue Lin; Yinchu Ma; Huixia Zhu; Mingfeng Shao; Xianzhu Yang; Wei Tao
Source: Self-asserted source
Pei Pei
grade
Preferred source (of 2)‎

Peer review (15 reviews for 9 publications/grants)

Review activity for ACS applied nano materials. (2)
Review activity for Acta biomaterialia. (2)
Review activity for Acta biomaterialia. (1)
Review activity for Advanced materials. (2)
Review activity for Advanced science. (3)
Review activity for Current microbiology. (1)
Review activity for International journal of nanomedicine (2)
Review activity for Molecular therapy oncolytics. (1)
Review activity for Molecular therapy. Oncology. (1)