Personal information

Other IDs

ResearcherID: K-5305-2018

Keywords

Glycosphingolipids, Glycoimmunology, IgM

Countries

Japan

Activities

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Employment (1)

National Institute of Advanced Industrial Science and Technology (AIST): Tsukuba, Ibaraki, JP

2006-04-01 to present (Bioproduction Research Institute)
Employment
Source: Self-asserted source
Tetsuya Okuda

Funding (5)

ケトン食摂取による脳内の糖脂質発現動態に関する研究

2015-04-01 to 2019-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
URL: https://app.dimensions.ai/details/grant/grant.5848236
GRANT_NUMBER: 15H02907
Source: Self-asserted source
Tetsuya Okuda via DimensionsWizard

がん特異的なコアフコシル化糖鎖を認識する抗体の創製

2015-04-01 to 2018-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
URL: https://app.dimensions.ai/details/grant/grant.5873323
GRANT_NUMBER: 15K15201
Source: Self-asserted source
Tetsuya Okuda via DimensionsWizard

Research of neutralizing antibody recognizing glycopeptides onto hepatitis C virus and basic studies for new diagnoses

2013-04-01 to 2017-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
URL: https://app.dimensions.ai/details/grant/grant.6114422
GRANT_NUMBER: 25293134
Source: Self-asserted source
Tetsuya Okuda via DimensionsWizard

Altered expression of glycoproteins and glycosphingolipids in a mouse model whose glycemic status is controlled by a low carbohydrate ketogenic diet

2012-04-01 to 2015-03-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
URL: https://app.dimensions.ai/details/grant/grant.6106038
GRANT_NUMBER: 24700859
Source: Self-asserted source
Tetsuya Okuda via DimensionsWizard

Altered expression of O-GlcNAc-modified proteins in a mouse model whose glycemic status is controlled by a low carbohydrate ketogenic diet

2010-01-01 to 2012-12-31 | Grant
Japan Society for the Promotion of Science (Tokyo, JP)
URL: https://app.dimensions.ai/details/grant/grant.6052227
GRANT_NUMBER: 22700780
Source: Self-asserted source
Tetsuya Okuda via DimensionsWizard

Works (36)

A simple procedure for preparing biotinylated immunoglobulin M from hybridoma culture medium

Protein Expression and Purification
2025-01 | Journal article
DOI: 10.1016/j.pep.2024.106595
Contributors: Tetsuya Okuda; Katsuya Kato
Source: check_circle
Crossref

Characterization of antibodies induced by immunization of mice with isoglobotrihexosylceramide (iGb3)

Biochemistry and Biophysics Reports
2024-12 | Journal article
DOI: 10.1016/j.bbrep.2024.101855
Contributors: Tetsuya Okuda
Source: check_circle
Crossref

Glycosphingolipids form characteristic-sized liposomes that correlate with their antibody-inducing activities in mice

Biochemical and Biophysical Research Communications
2022-12 | Journal article
DOI: 10.1016/j.bbrc.2022.09.094
Contributors: Tetsuya Okuda; Katsuya Kato
Source: check_circle
Crossref

A zirconia-based column chromatography system optimized for the purification of IgM from hybridoma culture supernatants

Analytical Biochemistry
2022-11 | Journal article
DOI: 10.1016/j.ab.2022.114900
Contributors: Tetsuya Okuda; Masahiro Kitamura; Katsuya Kato
Source: check_circle
Crossref

Identification of genes for variable regions of immunoglobulins that recognize sialylated glycans

Biochemical and Biophysical Research Communications
2021-08 | Journal article
DOI: 10.1016/j.bbrc.2021.06.039
Contributors: Tetsuya Okuda; Masahiro Kitamara; Shinjiro Kasahara; Katsuya Kato
Source: check_circle
Crossref

Application of the Antibody-Inducing Activity of Glycosphingolipids to Human Diseases

International Journal of Molecular Sciences
2021-04-06 | Journal article
DOI: 10.3390/ijms22073776
Contributors: Tetsuya Okuda
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Isolation and Characterization of Antibodies Induced by Immunization with TNF-α Inducible Globotetraosylceramide

International Journal of Molecular Sciences
2020-05-21 | Journal article
DOI: 10.3390/ijms21103632
Contributors: Tetsuya Okuda
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Data set for characterization of the glycosylation status of hepatic glycoproteins in mice fed a low-carbohydrate ketogenic diet

Data in Brief
2019-12 | Journal article
DOI: 10.1016/j.dib.2019.104604
Contributors: Tetsuya Okuda
Source: check_circle
Crossref

Dietary Control of Ganglioside Expression in Mammalian Tissues

International Journal of Molecular Sciences
2019-12-26 | Journal article
DOI: 10.3390/ijms21010177
Contributors: Tetsuya Okuda
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Induction of specific adaptive immune responses by immunization with newly designed artificial glycosphingolipids

Scientific Reports
2019-12-11 | Journal article
DOI: 10.1038/s41598-019-55088-9
Contributors: Tetsuya Okuda; Kayoko Shimizu; Satoshi Hasaba; Mutsuhiro Date
Source: check_circle
Crossref

A low-carbohydrate ketogenic diet induces the expression of very-low-density lipoprotein receptor in liver and affects its associated metabolic abnormalities

npj Science of Food
2019-12-02 | Journal article
DOI: 10.1038/s41538-019-0058-4
Contributors: Tetsuya Okuda
Source: check_circle
Crossref

A low-carbohydrate ketogenic diet promotes ganglioside synthesis via the transcriptional regulation of ganglioside metabolism-related genes

Scientific Reports
2019-05-20 | Journal article
DOI: 10.1038/s41598-019-43952-7
Contributors: Tetsuya Okuda
Source: check_circle
Crossref

Generation of anti-oligosaccharide antibodies that recognize mammalian glycoproteins by immunization with a novel artificial glycosphingolipid

Biochemical and Biophysical Research Communications
2018 | Journal article
DOI: 10.1016/j.bbrc.2018.02.113
WOSUID:

WOS:000428228400008
Contributors: Okuda, Tetsuya; Fukui, Asami
Source: Self-asserted source
Tetsuya Okuda via ResearcherID
grade
Preferred source (of 2)‎

Data set for characterization of TNF-α–inducible glycosphingolipids in vascular endothelial cells

Data in Brief
2018-12 | Journal article
DOI: 10.1016/j.dib.2018.09.059
Contributors: Tetsuya Okuda
Source: check_circle
Crossref

Data on immunoglobulin G antibodies induced by immunization of mice with globoside carrying very long-chain fatty acids

Data in Brief
2018-08 | Journal article
DOI: 10.1016/j.dib.2018.05.014
Contributors: Tetsuya Okuda
Source: check_circle
Crossref

Design of Carrier Molecules Suitable for Inducing Immunity to Oligosaccharide Antigens: Application to Anti-Glycoprotein Monoclonal Antibodies

2018-07-25 | Journal article
Source: Self-asserted source
Tetsuya Okuda

PUGNAc treatment provokes globotetraosylceramide accumulation in human umbilical vein endothelial cells

Biochemical and Biophysical Research Communications
2017 | Journal article
DOI: 10.1016/j.bbrc.2017.04.019
WOSUID:

WOS:000400954300012
Contributors: Okuda, Tetsuya
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Western blot data using two distinct anti-O-GlcNAc monoclonal antibodies showing unique glycosylation status on cellular proteins under 2-deoxy-d-glucose treatment.

Data in brief
2017 | Journal article
DOI: 10.1016/j.dib.2016.12.001
WOSUID:

MEDLINE:28054006
Contributors: Okuda, Tetsuya
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

A very low carbohydrate ketogenic diet increases hepatic glycosphingolipids related to regulation of insulin signalling

Journal of Functional Foods
2016 | Journal article
DOI: 10.1016/j.jff.2015.11.040
WOSUID:

WOS:000371281900007
Contributors: Okuda, Tetsuya; Morita, Naoki
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Altered expression of O-GlcNAc-modified proteins in a mouse model whose glycemic status is controlled by a low carbohydrate ketogenic diet

Glycoconjugate Journal
2013 | Journal article
DOI: 10.1007/s10719-013-9482-x
WOSUID:

WOS:000325429000005
Contributors: Okuda, Tetsuya; Fukui, Asami; Morita, Naoki
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

A very low carbohydrate ketogenic diet prevents the progression of hepatic steatosis caused by hyperglycemia in a juvenile obese mouse model

Nutrition & Diabetes
2012 | Journal article
DOI: 10.1038/nutd.2012.24
WOSUID:

WOS:000314530000001
Contributors: Okuda, T.; Morita, N.
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Structural characterization and dynamics of globotetraosylceramide in vascular endothelial cells under TNF-alpha stimulation

Glycoconjugate Journal
2010 | Journal article
DOI: 10.1007/s10719-009-9277-2
WOSUID:

WOS:000274493100010
Contributors: Okuda, Tetsuya; Nakakita, Sin-ichi; Nakayama, Ken-ichi
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

A novel, promoter-based, target-specific assay identifies 2-deoxy-d-glucose as an inhibitor of globotriaosylceramide biosynthesis

Febs Journal
2009 | Journal article
DOI: 10.1111/j.1742-4658.2009.07215.x
WOSUID:

WOS:000269366500016
Contributors: Okuda, Tetsuya; Furukawa, Koichi; Nakayama, Ken-ichi
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Clathrin-Mediated Endocytosis of Quantum Dot-Peptide Conjugates in Living Cells

Acs Nano
2009 | Journal article
DOI: 10.1021/nn900663r
WOSUID:

WOS:000269145000049
Contributors: Anas, Abdulaziz; Okuda, Tetsuya; Kawashima, Nagako; Nakayama, Kenichi; Itoh, Tamitake; Ishikawa, Mitsuru; Biju, Vasudevanpillai
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Mechanism of abnormal growth in astrocytes derived from a mouse model of GM2 gangliosidosis

Journal of Neurochemistry
2009 | Journal article
DOI: 10.1111/j.1471-4159.2009.06391.x
WOSUID:

WOS:000270901600013
Contributors: Kawashima, Nagako; Tsuji, Daisuke; Okuda, Tetsuya; Itoh, Kohji; Nakayama, Ken-ichi
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Study on Abnormal Proliferation Mechanism of Astrocytes Derived from GM2 Gangliosidosis Model Mice

Glycobiology
2009 | Journal article
WOSUID:

WOS:000270707700112
Contributors: Kawashima, Nagako; Tsuji, Daisuke; Okuda, Tetsuya; Itoh, Kohji; Nakayama, Ken-Ichi
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Cloning and Characterization of the Human Gb3/CD77 Synthase Gene Promoter

Glycobiology
2008 | Journal article
WOSUID:

WOS:000260141400076
Contributors: Okuda, Tetsuya; Nakayama, Ken-ichi
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Identification and characterization of the human Gb3/CD77 synthase gene promoter

Glycobiology
2008 | Journal article
DOI: 10.1093/glycob/cwn082
WOSUID:

WOS:000261280200002
Contributors: Okuda, Tetsuya; Nakayama, Ken-ichi
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Roles of glycolipids in the development and maintenance of nervous tissues

Functional Glycomics
2006 | Journal article
DOI: 10.1016/S0076-6879(06)17004-4
WOSUID:

WOS:000242549400004
Contributors: Furukawa, Koichi; Okuda, Tetsuya; Furukawa, Keiko
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to vVerotoxins

Journal of Biological Chemistry
2006 | Journal article
DOI: 10.1074/jbc.M600057200
WOSUID:

WOS:000236594300050
Contributors: Okuda, T; Tokuda, N; Numata, S; Ito, M; Ohta, M; Kawamura, K; Wiels, J; Urano, T; Tajima, O; Furukawa, K
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells

Proceedings of the National Academy of Sciences of the United States of America
2005 | Journal article
DOI: 10.1073/pnas.0503658102
WOSUID:

WOS:000231102400056
Contributors: Hamamura, K; Furukawa, K; Hayashi, T; Hattori, T; Nakano, J; Nakashima, H; Okuda, T; Mizutani, H; Hattori, H; Ueda, M et al.
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Glycosphingolipids in engineered mice: insights into function

Seminars in Cell & Developmental Biology
2004 | Journal article
DOI: 10.1016/j.semcdb.2004.03.006
WOSUID:

WOS:000222704900003
Contributors: Furukawa, K; Tokuda, N; Okuda, T; Tajima, O
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Implication of Gb3 expression in vivo in hemolytic uremic syndrome

Glycobiology
2004 | Journal article
WOSUID:

WOS:000224206400392
Contributors: Okuda, T; Tokuda, N; Numata, S; Ito, M; Ohta, M; Kawamura, K; Wiels, J; Fujii, Y; Urano, T; Tajima, O et al.
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Mouse N-acetylgalactosamine 4-sulfotransferases-1 and -2. Molecular cloning, expression, chromosomal mapping and detection of their activity with GalNAc beta 1-4GlcNAc beta 1-octyl

Journal of Biochemistry
2003 | Journal article
DOI: 10.1093/jb/mvg118
WOSUID:

WOS:000184827800014
Contributors: Okuda, T; Sawada, T; Nakano, H; Matsubara, K; Matsuda, Y; Fukuta, M; Habuchi, O
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Molecular cloning and characterization of GalNAc (4-sulfotransferase expressed in human pituitary gland

Journal of Biological Chemistry
2000 | Journal article
DOI: 10.1074/jbc.M007983200
WOSUID:

WOS:000166039500108
Contributors: Okuda, T; Mita, S; Yamauchi, S; Fukuta, N; Nakano, H; Sawada, T; Habuchi, O
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Molecular cloning, expression, and chromosomal mapping of human chondroitin 4-sulfotransferase, whose expression pattern in human tissues is different from that of chondroitin 6-sulfotransferase

Journal of Biochemistry
2000 | Journal article
DOI: 10.1093/oxfordjournals.jbchem.a022813
WOSUID:

WOS:000165201800008
Contributors: Okuda, T; Mita, S; Yamauchi, S; Matsubara, T; Yagi, F; Yamamori, D; Fukuta, M; Kuroiwa, A; Matsuda, Y; Habuchi, O
Source: Self-asserted source
Tetsuya Okuda via ResearcherID

Peer review (1 review for 1 publication/grant)

Review activity for Journal of translational medicine. (1)
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