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Employment (6)

苏州系统医学研究所: 苏州市, 江苏省, CN

2014-10-01 to present | 研究员
Employment
Source: Self-asserted source
F. XIAOFENG QIN

中国医学科学院基础医学研究所中国协和医科大学: 北京, 北京市, CN

2012 to 2015 | 客座教授 (基础医学院)
Employment
Source: Self-asserted source
F. XIAOFENG QIN

得克萨斯州大学MD安德森癌症中心: 圣马科斯, 得克萨斯州, US

2010 to 2015 | 兼职教授，博士生导师 (肿瘤医学部、免疫系)
Employment
Source: Self-asserted source
F. XIAOFENG QIN

中山大学: 广州市, 广东省, CN

2010-09-25 to 2014-09-24 | 教授 (生命科学学院)
Employment
Source: Self-asserted source
F. XIAOFENG QIN

得克萨斯州大学MD安德森癌症中心: 圣马科斯, 德克萨斯州, US

2003 to 2010 | 助理教授，博士生导师 (得克萨斯州大学生物科学研究生院)
Employment
Source: Self-asserted source
F. XIAOFENG QIN

加州理工学院: 洛杉矶, 加利福尼亚州, US

1998-11-06 to 2003 | 博士后
Employment
Source: Self-asserted source
F. XIAOFENG QIN

Education and qualifications (3)

洛克菲勒大学: 纽约, US

1991 to 1998 | 博士
Education
Source: Self-asserted source
F. XIAOFENG QIN

中国科学院微生物研究所: 北京, 北京市, CN

1985 to 1989 | 理学硕士
Education
Source: Self-asserted source
F. XIAOFENG QIN

南京大学: 南京市, 江苏省, CN

1981 to 1985 | 理学学士 (生物化学系)
Education
Source: Self-asserted source
F. XIAOFENG QIN

Professional activities (10)

西交利物浦大学: 苏州市, 江苏省, CN

2016 to present | 名誉教授
Invited position
Source: Self-asserted source
F. XIAOFENG QIN

中华医学会: 北京, 北京市, CN

2021-03-10 | 医学科学技术奖二等奖
Distinction
Source: Self-asserted source
F. XIAOFENG QIN

南开医院: 天津, 天津市, CN

2017-08-01 to 2020-08-01 | 特聘教授 (南开临床学院)
Invited position
Source: Self-asserted source
F. XIAOFENG QIN

中共苏州工业园区工作委员会，苏州工业园区管理委员会: 苏州市, 江苏省, CN

2015-12 | 金鸡湖双百人才计划科技领军人才
Distinction
Source: Self-asserted source
F. XIAOFENG QIN

美国癌症协会: 亚特兰大, US

2009-10-01 | 美国癌症协会研究学者奖
Distinction
Source: Self-asserted source
F. XIAOFENG QIN

美国得克萨斯州大学MD Anderson癌症研究中心: 圣马科斯, 得克萨斯州, US

2003 | 美国得克萨斯州大学MD Anderson癌症研究中心特设癌症研究基金学者奖
Distinction
Source: Self-asserted source
F. XIAOFENG QIN

美国得克萨斯州大学: 圣马科斯, 得克萨斯州, US

2003 | 美国得克萨斯州大学Wilson Stone 纪念奖
Distinction
Source: Self-asserted source
F. XIAOFENG QIN

中国科学院: 北京, 北京市, CN

1991-10 | 中国科学院科技进步一等奖
Distinction
Source: Self-asserted source
F. XIAOFENG QIN

中国科学院: 北京, 北京市, CN

1990-12 | 中国科学院科技进步二等奖
Distinction
Source: Self-asserted source
F. XIAOFENG QIN

国家计委，国家科委，财政部: 北京, 北京市, CN

1989-09 | “七五”国家重点科技攻关专题优异成绩集体奖
Distinction
Source: Self-asserted source
F. XIAOFENG QIN

Funding (9)

免疫激活，免疫逃逸在肿瘤免疫治疗中的作用及其调控机制的研究

2019-01 to 2019-12 | Grant
国家外专局 (北京市, CN)
GRANT_NUMBER:

G20190001639
Source: Self-asserted source
F. XIAOFENG QIN

新型免疫负调控分子CD38介导PD-1/PD-L1免疫检查点阻断治疗耐受的机制研究

2019-01 to 2019-12 | Grant
国家外专局 (北京市, CN)
GRANT_NUMBER:

G20190001633
Source: Self-asserted source
F. XIAOFENG QIN

新型免疫负调控分子CD38介导PD-1/PD-L1免疫检查点阻断治疗耐受的机制研究

2018-01 to 2021-12 | Grant
National Natural Science Foundation of China (北京市, CN)
GRANT_NUMBER:

81773058
Source: Self-asserted source
F. XIAOFENG QIN

抑制病毒复制的干扰素诱导基因及药物的功能和机制研究

2017-11 to 2018-11 | Grant
中国医学科学院 (北京市, CN)
GRANT_NUMBER:

2017NL31002
Source: Self-asserted source
F. XIAOFENG QIN

重大疾病的系统生物学研究

2016-11 to 2017-11 | Grant
中国医学科学院 (北京市, CN)
GRANT_NUMBER:

2016ZX310194
Source: Self-asserted source
F. XIAOFENG QIN

系统医学技术研究与应用

2016-09 to 2020-12 | Grant
中国医学科学院 (北京市, CN)
GRANT_NUMBER:

2016-I2M-1-005
Source: Self-asserted source
F. XIAOFENG QIN

埃博拉应急研究子课题-埃博拉病毒与宿主因子相互作用研究

2015-07 to 2017-12 | Grant
National Natural Science Foundation of China (北京市, CN)
GRANT_NUMBER:

81590765
Source: Self-asserted source
F. XIAOFENG QIN

抗埃博拉病毒应急药物的研发

2015-01 to 2018-12 | Grant
国家科技部 (北京市, CN)
GRANT_NUMBER:

2015ZX09102023
Source: Self-asserted source
F. XIAOFENG QIN

合成生物器件干预膀胱癌的基础研究

2014-01 to 2018-08 | Grant
国家科技部 (北京市, CN)
GRANT_NUMBER:

2014CB745200
Source: Self-asserted source
F. XIAOFENG QIN

Works (50 of 79)

Items per page:
Page 1 of 2

Evolving roles of CD38 metabolism in solid tumour microenvironment

British Journal of Cancer
2023-02-16 | Journal article
DOI: 10.1038/s41416-022-02052-6
Contributors: Long Gao; Xiaohong Du; Jiabin Li; F. Xiao-Feng Qin
Source: check_circle
Crossref

The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.

Cell death & disease
2021-07-05 | Journal article
DOI: 10.1038/s41419-021-03968-2
PMID: 34226519
PMC: PMC8256983
Source: Self-asserted source
F. XIAOFENG QIN

IL-2 regulates tumor-reactive CD8<sup>+</sup> T cell exhaustion by activating the aryl hydrocarbon receptor.

Nature immunology
2021-01-11 | Journal article
DOI: 10.1038/s41590-020-00850-9
PMID: 33432230
Source: Self-asserted source
F. XIAOFENG QIN

Direct inhibitory effect on viral entry of influenza A and SARS-CoV-2 viruses by azithromycin.

Cell proliferation
2020-11-19 | Journal article
DOI: 10.1111/cpr.12953
PMID: 33211371
PMC: PMC7744835
Source: Self-asserted source
F. XIAOFENG QIN
grade
Preferred source (of 2)‎

Tissue-specific deconvolution of immune cell composition by integrating bulk and single-cell transcriptomes.

Bioinformatics (Oxford, England)
2020-02-01 | Journal article
DOI: 10.1093/bioinformatics/btz672
PMID: 31504185
Source: Self-asserted source
F. XIAOFENG QIN

Combinatorial screening of a panel of FDA-approved drugs identifies several candidates with anti-Ebola activities.

Biochemical and biophysical research communications
2019-12-02 | Journal article
DOI: 10.1016/j.bbrc.2019.11.065
PMID: 31806372
Source: Self-asserted source
F. XIAOFENG QIN
grade
Preferred source (of 2)‎

Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation.

Cell reports
2019-12-01 | Journal article
DOI: 10.1016/j.celrep.2019.11.041
PMID: 31825835
PMC: PMC6996557
Source: Self-asserted source
F. XIAOFENG QIN

Azithromycin Protects against Zika virus Infection by Upregulating virus-induced Type I and III Interferon Responses.

Antimicrobial agents and chemotherapy
2019-09-16 | Journal article
DOI: 10.1128/aac.00394-19
PMID: 31527024
PMC: PMC6879226
Source: Self-asserted source
F. XIAOFENG QIN

Noncanonical Role of FBXO6 in Regulating Antiviral Immunity.

Journal of immunology (Baltimore, Md. : 1950)
2019-07-15 | Journal article
DOI: 10.4049/jimmunol.1801557
PMID: 31308089
Source: Self-asserted source
F. XIAOFENG QIN

Targeting the tumor microenvironment to overcome immune checkpoint blockade therapy resistance.

Immunology letters
2019-03-15 | Journal article
DOI: 10.1016/j.imlet.2019.03.006
PMID: 30885690
Source: Self-asserted source
F. XIAOFENG QIN

Inhibition of Influenza A Virus Replication by TRIM14 via Its Multifaceted Protein-Protein Interaction With NP.

Frontiers in microbiology
2019-02-26 | Journal article
DOI: 10.3389/fmicb.2019.00344
PMID: 30873142
PMC: PMC6401474
Source: Self-asserted source
F. XIAOFENG QIN

Concomitant type I IFN and M-CSF signaling reprograms monocyte differentiation and drives pro-tumoral arginase production.

EBioMedicine
2018-12-07 | Journal article
DOI: 10.1016/j.ebiom.2018.11.062
PMID: 30528455
PMC: PMC6354658
Source: Self-asserted source
F. XIAOFENG QIN

Identification of <i>TRIM14</i> as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx.

Frontiers in immunology
2018-08-13 | Journal article
DOI: 10.3389/fimmu.2018.01872
PMID: 30150992
PMC: PMC6100580
Source: Self-asserted source
F. XIAOFENG QIN

CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade.

Cancer discovery
2018-07-16 | Journal article
DOI: 10.1158/2159-8290.cd-17-1033
PMID: 30012853
PMC: PMC6205194
Source: Self-asserted source
F. XIAOFENG QIN

seq-ImmuCC: Cell-Centric View of Tissue Transcriptome Measuring Cellular Compositions of Immune Microenvironment From Mouse RNA-Seq Data.

Frontiers in immunology
2018-06-05 | Journal article
DOI: 10.3389/fimmu.2018.01286
PMID: 29922297
PMC: PMC5996037
Source: Self-asserted source
F. XIAOFENG QIN

Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses

Science Advances
2018-05-04 | Journal article
DOI: 10.1126/sciadv.aar2824
Contributors: Qingxiang Liu; Yaoxing Wu; Yunfei Qin; Jiajia Hu; Weihong Xie; F. Xiao-Feng Qin; Jun Cui
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation.

Cancer cell
2018-03-01 | Journal article
DOI: 10.1016/j.ccell.2018.02.005
PMID: 29533786
Source: Self-asserted source
F. XIAOFENG QIN

STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells.

The Journal of clinical investigation
2018-02-12 | Journal article
DOI: 10.1172/jci96329
PMID: 29431732
PMC: PMC5824876
Source: Self-asserted source
F. XIAOFENG QIN

A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells.

Nature cell biology
2017-12-11 | Journal article
DOI: 10.1038/s41556-017-0002-2
PMID: 29230018
Source: Self-asserted source
F. XIAOFENG QIN

Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice.

EBioMedicine
2017-09-28 | Journal article
DOI: 10.1016/j.ebiom.2017.09.034
PMID: 29033372
PMC: PMC5652284
Source: Self-asserted source
F. XIAOFENG QIN

Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells.

Nature communications
2017-05-10 | Journal article
DOI: 10.1038/ncomms15207
PMID: 28488695
PMC: PMC5436221
Source: Self-asserted source
F. XIAOFENG QIN

25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model.

Immunity
2017-03-14 | Journal article
DOI: 10.1016/j.immuni.2017.02.012
PMID: 28314593
PMC: PMC5957489
Source: Self-asserted source
F. XIAOFENG QIN

Generation of a Live Attenuated Influenza Vaccine that Elicits Broad Protection in Mice and Ferrets.

Cell host & microbe
2017-03-01 | Journal article
DOI: 10.1016/j.chom.2017.02.007
PMID: 28279345
Source: Self-asserted source
F. XIAOFENG QIN

A human programmed death-ligand 1-expressing mouse tumor model for evaluating the therapeutic efficacy of anti-human PD-L1 antibodies.

Scientific reports
2017-02-16 | Journal article
DOI: 10.1038/srep42687
PMID: 28202921
PMC: PMC5311961
Source: Self-asserted source
F. XIAOFENG QIN

Screening for Novel Small-Molecule Inhibitors Targeting the Assembly of Influenza Virus Polymerase Complex by a Bimolecular Luminescence Complementation-Based Reporter System.

Journal of virology
2017-02-14 | Journal article
DOI: 10.1128/jvi.02282-16
PMID: 28031371
PMC: PMC5309938
Source: Self-asserted source
F. XIAOFENG QIN

Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication.

Cellular & molecular immunology
2017-02-13 | Journal article
DOI: 10.1038/cmi.2016.67
PMID: 28194021
PMC: PMC5843613
Source: Self-asserted source
F. XIAOFENG QIN

Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity.

Oncoimmunology
2017-01-19 | Journal article
DOI: 10.1080/2162402x.2017.1282589
PMID: 28405506
PMC: PMC5384362
Source: Self-asserted source
F. XIAOFENG QIN

Inference of immune cell composition on the expression profiles of mouse tissue.

Scientific reports
2017-01-13 | Journal article
DOI: 10.1038/srep40508
PMID: 28084418
PMC: PMC5233994
Source: Self-asserted source
F. XIAOFENG QIN

A Novel Function of F-Box Protein FBXO17 in Negative Regulation of Type I IFN Signaling by Recruiting PP2A for IFN Regulatory Factor 3 Deactivation.

Journal of immunology (Baltimore, Md. : 1950)
2016-12-12 | Journal article
DOI: 10.4049/jimmunol.1601009
PMID: 27956528
PMC: PMC5220122
Source: Self-asserted source
F. XIAOFENG QIN

Pre-instillation of tumor microparticles enhances intravesical chemotherapy of nonmuscle-invasive bladder cancer through a lysosomal pathway.

Biomaterials
2016-10-24 | Journal article
DOI: 10.1016/j.biomaterials.2016.10.036
PMID: 27810645
Source: Self-asserted source
F. XIAOFENG QIN

Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression.

Oncoimmunology
2016-09-26 | Journal article
DOI: 10.1080/2162402x.2016.1234570
PMID: 27999749
PMC: PMC5139626
Source: Self-asserted source
F. XIAOFENG QIN

TRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A protein.

Scientific reports
2016-08-31 | Journal article
DOI: 10.1038/srep32336
PMID: 27578425
PMC: PMC5006124
Source: Self-asserted source
F. XIAOFENG QIN

Understanding the pathogenic evolution of Zika virus.

Science China. Life sciences
2016-05-20 | Journal article
DOI: 10.1007/s11427-016-5069-7
PMID: 27207138
Source: Self-asserted source
F. XIAOFENG QIN

Isotetrandrine ameliorates tert-butyl hydroperoxide-induced oxidative stress through upregulation of heme oxygenase-1 expression.

Experimental biology and medicine (Maywood, N.J.)
2016-05-02 | Journal article
DOI: 10.1177/1535370216647122
PMID: 27190261
PMC: PMC4994909
Source: Self-asserted source
F. XIAOFENG QIN

Complex Regulation Pattern of IRF3 Activation Revealed by a Novel Dimerization Reporter System.

Journal of immunology (Baltimore, Md. : 1950)
2016-04-04 | Journal article
DOI: 10.4049/jimmunol.1502458
PMID: 27045107
Source: Self-asserted source
F. XIAOFENG QIN

Delivery of oncolytic adenovirus into the nucleus of tumorigenic cells by tumor microparticles for virotherapy.

Biomaterials
2016-02-23 | Journal article
DOI: 10.1016/j.biomaterials.2016.02.025
PMID: 26950165
Source: Self-asserted source
F. XIAOFENG QIN

Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression.

Oncoimmunology
2016-02-18 | Journal article
DOI: 10.1080/2162402x.2015.1118599
PMID: 27141404
PMC: PMC4839324
Source: Self-asserted source
F. XIAOFENG QIN

Functional Genomics Reveals Linkers Critical for Influenza Virus Polymerase.

Journal of virology
2015-12-30 | Journal article
DOI: 10.1128/jvi.02400-15
PMID: 26719244
PMC: PMC4810648
Source: Self-asserted source
F. XIAOFENG QIN

New targets for controlling Ebola virus disease.

National science review
2015-07-17 | Journal article
DOI: 10.1093/nsr/nwv043
PMID: 26550528
PMC: PMC4632854
Source: Self-asserted source
F. XIAOFENG QIN

The antioxidative potential of farrerol occurs via the activation of Nrf2 mediated HO-1 signaling in RAW 264.7 cells.

Chemico-biological interactions
2015-06-22 | Journal article
DOI: 10.1016/j.cbi.2015.06.032
PMID: 26111761
Source: Self-asserted source
F. XIAOFENG QIN

Network of co-mutations in Ebola virus genome predicts the disease lethality.

Cell research
2015-05-15 | Journal article
DOI: 10.1038/cr.2015.54
PMID: 25976404
PMC: PMC4456622
Source: Self-asserted source
F. XIAOFENG QIN

The mutually regulatory loop of epithelial-mesenchymal transition and immunosuppression in cancer progression.

Oncoimmunology
2015-02-03 | Journal article
DOI: 10.1080/2162402x.2014.1002731
PMID: 26155392
PMC: PMC4485725
Source: Self-asserted source
F. XIAOFENG QIN

Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms.

Scientific reports
2014-12-03 | Journal article
DOI: 10.1038/srep07242
PMID: 25467815
PMC: PMC4252895
Source: Self-asserted source
F. XIAOFENG QIN

Integrating computational modeling and functional assays to decipher the structure-function relationship of influenza virus PB1 protein.

Scientific reports
2014-11-26 | Journal article
DOI: 10.1038/srep07192
PMID: 25424584
PMC: PMC4244630
Source: Self-asserted source
F. XIAOFENG QIN

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.

Nature communications
2014-10-28 | Journal article
DOI: 10.1038/ncomms6241
PMID: 25348003
PMC: PMC4212319
Source: Self-asserted source
F. XIAOFENG QIN

cMyb regulates hematopoietic stem/progenitor cell mobilization during zebrafish hematopoiesis.

Blood
2011-08-19 | Journal article
DOI: 10.1182/blood-2011-03-342501
PMID: 21856868
Source: Self-asserted source
F. XIAOFENG QIN

Generation of an immune microenvironment as a novel mechanism for myotoxins to potentiate genetic vaccines.

Vaccine
2010-11-01 | Journal article
DOI: 10.1016/j.vaccine.2010.09.084
PMID: 20937320
Source: Self-asserted source
F. XIAOFENG QIN

Synergistic effect of IL-6 and IL-4 in driving fate revision of natural Foxp3+ regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950)
2010-10-06 | Journal article
DOI: 10.4049/jimmunol.0901948
PMID: 20926793
Source: Self-asserted source
F. XIAOFENG QIN

Cutting edge: Hematopoietic-derived APCs select regulatory T cells in thymus.

Journal of immunology (Baltimore, Md. : 1950)
2010-08-27 | Journal article
DOI: 10.4049/jimmunol.0900665
PMID: 20802149
PMC: PMC3325783
Source: Self-asserted source
F. XIAOFENG QIN

Characterization of a potent non-cytotoxic shRNA directed to the HIV-1 co-receptor CCR5.

Genetic vaccines and therapy
2009-06-10 | Journal article
DOI: 10.1186/1479-0556-7-8
PMID: 19515239
PMC: PMC2701936
Source: Self-asserted source
F. XIAOFENG QIN
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