Personal information

Emails & domains

Verified email domains

Other IDs

Scopus Author ID: 57205694261

Keywords

Alpha-emitter, Targeted radionuclide therapy, Pretargeting, Click-chemistry, Molecular Imaging, PET, PDAC, Stroma

Countries

France

Activities

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Employment (5)

Institut de Chimie Moléculaire de l'Université de Bourgogne: Dijon, FR

2024-09-01 to present | Junior Professor (Chaire Professeur Junior) (RITM)
Employment
Source: Self-asserted source
Sophie Poty

Institut de Chimie Moléculaire de l'Université de Bourgogne: Dijon, FR

2023-10-01 to 2024-08-31 | Post-doctoral fellow RHU CASSIOPEIA (RITM)
Employment
Source: Self-asserted source
Sophie Poty

Institut de Recherche en Cancérologie de Montpellier: Montpellier, Languedoc-Roussillon, FR

2019-07-01 to 2023-09-30 | Post-doctoral researcher (Radiobiologie pour la radiothérapie vectorisée et personalisée)
Employment
Source: Self-asserted source
Sophie Poty

Memorial Sloan Kettering Cancer Center: New York, NY, US

2016-01-06 to 2019-06-05 | Post-doctoral researcher (Radiology)
Employment
Source: Self-asserted source
Sophie Poty

Institut de Chimie Moléculaire de l'Université de Bourgogne: Dijon, FR

2012-09-01 to 2015-12-05 | PhD Student (PP2A)
Employment
Source: Self-asserted source
Sophie Poty

Education and qualifications (3)

Université de Bourgogne: Dijon, Bourgogne, FR

2012-01-09 to 2015-05-12 | Doctor of Philosophy - Chemistry (ICMUB)
Qualification
Source: Self-asserted source
Sophie Poty

Université de Bourgogne: Dijon, Bourgogne, FR

2010-09-01 to 2012-09-01 | Master's degree in Molecular Chemistry
Qualification
Source: Self-asserted source
Sophie Poty

Université de Bourgogne: Dijon, Bourgogne, FR

2007-09-01 to 2010-09-01 | Licence's degree in Chemistry
Qualification
Source: Self-asserted source
Sophie Poty

Funding (13)

Chaire Professeur Junior (Junior Professorship)

2024-09 to 2030-08 | Grant
Agence Nationale de la Recherche (Paris, FR)
Source: Self-asserted source
Sophie Poty

ECM-TRACER

2022-07 to 2024-06 | Grant
France Life Imaging (Montpellier, FR)
Source: Self-asserted source
Sophie Poty

Recherche et Société

2021-07 to 2024-06 | Grant
Région Occitanie Pyrénées-Méditerranée (Montpellier, FR)
Source: Self-asserted source
Sophie Poty

Covid-19 exceptional funding

2021-07 to 2021-12 | Grant
Fondation ARC (Paris, FR)
Source: Self-asserted source
Sophie Poty

Allocation doctorale

2020-12 to 2023-12 | Grant
Région Occitanie Pyrénées-Méditerranée (Montpellier, FR)
Source: Self-asserted source
Sophie Poty

PRECIRIX industrial collaboration

2020-10 to 2023-10 | Contract
PRECIRIX (Brussels, BE)
Source: Self-asserted source
Sophie Poty

Postdoctoral fellowship

2019-07 to 2021-07 | Grant
Fondation ARC (Paris, FR)
Source: Self-asserted source
Sophie Poty

Translational Research Grant

2019-05 to 2021-05 | Grant
MSKCC Imaging and Radiation Sciences Program (New York, US)
Source: Self-asserted source
Sophie Poty

Postdoctoral fellowship

2017-04 to 2019-04 | Grant
Fondation François Wallace Monahan (New York, US)
Source: Self-asserted source
Sophie Poty

Private funding

2016-10 to 2016-10 | Award
Fondation Carnot (Paris, FR)
Source: Self-asserted source
Sophie Poty

Private funding

2016-10 to 2016-10 | Award
Fondation Philippe (New York, US)
Source: Self-asserted source
Sophie Poty

Short Term Scientific Mission

2013-01 to 2015-03 | Grant
COST action PET/MRI - Theranostics (-, FR)
Source: Self-asserted source
Sophie Poty

Bourse Ministérielle

2012-09 to 2015-09 | Grant
Ministère de l'Enseignement Supérieur et de la Recherche (Paris, FR)
Source: Self-asserted source
Sophie Poty

Works (23)

Optimizing the Therapeutic Index of sdAb-Based Radiopharmaceuticals Using Pretargeting.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
2024-10-01 | Journal article
DOI: 10.2967/jnumed.124.267624
PMID: 39266288
Contributors: Poty S; Ordas L; Dekempeneer Y; Parach AA; Navarro L; Santens F; Dumauthioz N; Bardiès M; Lahoutte T; D'Huyvetter M et al.
Source: Self-asserted source
Sophie Poty

Gadolinium-Based Nanoparticles Sensitize Ovarian Peritoneal Carcinomatosis to Targeted Radionuclide Therapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
2023-12-01 | Journal article
DOI: 10.2967/jnumed.123.265418
PMID: 37857502
PMC: PMC10690115
Contributors: Garcia-Prada CD; Carmes L; Atis S; Parach A; Bertolet A; Jarlier M; Poty S; Garcia DS; Shin WG; Du Manoir S et al.
Source: Self-asserted source
Sophie Poty

Fc-engineered monoclonal antibodies to reduce off-target liver uptake.

EJNMMI research
2023-09-11 | Journal article
DOI: 10.1186/s13550-023-01030-0
PMID: 37697076
PMC: PMC10495296
Contributors: Mangeat T; Matthieu Gracia; Pichard A; Poty S; Martineau P; Bruno ROBERT; Emmanuel Deshayes
Source: Self-asserted source
Sophie Poty

In vivo validation of 68Ga-labeled AMD3100 conjugates for PET imaging of CXCR4

Nuclear Medicine and Biology
2023-05 | Journal article
DOI: 10.1016/j.nucmedbio.2023.108335
Part of ISSN: 0969-8051
Contributors: Isaline Renard; Juozas Domarkas; Sophie Poty; Benjamin P. Burke; David P. Roberts; Christine Goze; Franck Denat; Christopher J. Cawthorne; Stephen J. Archibald
Source: Self-asserted source
Sophie Poty

Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer.

European journal of medicinal chemistry
2022-06-02 | Journal article
DOI: 10.1016/j.ejmech.2022.114504
PMID: 35724566
Contributors: Sophie Poty; Jian-Fei Bai; Majjigapu SR; Sordat B; Poty S; Vogel P; Elías-Rodríguez P; Moreno-Vargas AJ; Carmona AT; Caffa I et al.
Source: Self-asserted source
Sophie Poty

From the target cell theory to a more integrated view of radiobiology in Targeted radionuclide therapy: The Montpellier group's experience.

Nuclear medicine and biology
2021-12-06 | Journal article
DOI: 10.1016/j.nucmedbio.2021.11.005
PMID: 34922279
Contributors: Sophie Poty; Pouget JP; Santoro L; Piron B; Paillas S; Riad LADJOHOUNLOU; Pichard A; Poty S; Deshayes E; Julie Constanzo et al.
Source: Self-asserted source
Sophie Poty

Therapeutic antibodies - natural and pathological barriers and strategies to overcome them.

Pharmacology & therapeutics
2021-10-20 | Journal article
DOI: 10.1016/j.pharmthera.2021.108022
PMID: 34687769
PMC: PMC8527648
Contributors: Sophie Poty; Al Ojaimi Y; Blin T; Lamamy J; Gracia M; Pitiot A; Denevault-Sabourin C; Joubert N; Jean-Pierre POUGET; Gouilleux-Gruart V et al.
Source: Self-asserted source
Sophie Poty

Targeted Radionuclide Therapy Using Auger Electron Emitters: The Quest for the Right Vector and the Right Radionuclide.

Pharmaceutics
2021-06-29 | Journal article
DOI: 10.3390/pharmaceutics13070980
PMID: 34209637
PMC: PMC8309076
Contributors: Sophie Poty; Idrissou MB; Pichard A; Bryan Pi Ern Tee; Tibor Kibedi; Poty S; Jean-Pierre POUGET
Source: Self-asserted source
Sophie Poty

<sup>89</sup>Zr-PET imaging of DNA double-strand breaks for the early monitoring of response following α- And β-particle radioimmunotherapy in a mouse model of pancreatic ductal adenocarcinoma

Theranostics
2020 | Journal article
DOI: 10.7150/thno.44772
EID:

2-s2.0-85085854599

Part of ISSN: 18387640
Contributors: Poty, S.; Mandleywala, K.; O’Neill, E.; Knight, J.C.; Cornelissen, B.; Lewis, J.S.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

Antibody-drug conjugates based on gold compounds

2020-01-16 | Patent
Source: Self-asserted source
Sophie Poty

A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals

Nuclear Medicine and Biology
2019 | Journal article
DOI: 10.1016/j.nucmedbio.2019.04.005
EID:

2-s2.0-85065863004

Part of ISSN: 18729614 09698051
Contributors: Sharma, S.K.; Lyashchenko, S.K.; Park, H.A.; Pillarsetty, N.; Roux, Y.; Wu, J.; Poty, S.; Tully, K.M.; Poirier, J.T.; Lewis, J.S.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

Innovative Magnetic Nanoparticles for PET/MRI Bimodal Imaging

ACS Omega
2019 | Journal article
DOI: 10.1021/acsomega.8b03283
EID:

2-s2.0-85061132443

Part of ISSN: 24701343
Contributors: Thomas, G.; Boudon, J.; Maurizi, L.; Moreau, M.; Walker, P.; Severin, I.; Oudot, A.; Goze, C.; Poty, S.; Vrigneaud, J.-M. et al.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

Leveraging bioorthogonal click chemistry to improve <sup>225</sup> AC-radioimmunotherapy of pancreatic ductal adenocarcinoma

Clinical Cancer Research
2019 | Journal article
DOI: 10.1158/1078-0432.CCR-18-1650
EID:

2-s2.0-85060010563

Part of ISSN: 15573265 10780432
Contributors: Poty, S.; Carter, L.M.; Mandleywala, K.; Membreno, R.; Abdel-Atti, D.; Ragupathi, A.; Scholz, W.W.; Zeglis, B.M.; Lewis, J.S.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

Trastuzumab gold-conjugates: Synthetic approach and: In vitro evaluation of anticancer activities in breast cancer cell lines

Chemical Communications
2019 | Journal article
DOI: 10.1039/c8cc08769e
EID:

2-s2.0-85060617422

Part of ISSN: 1364548X 13597345
Contributors: Curado, N.; Dewaele-Le Roi, G.; Poty, S.; Lewis, J.S.; Contel, M.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

Preclinical optimization of antibody-based radiopharmaceuticals for cancer imaging and radionuclide therapy—Model, vector, and radionuclide selection

Journal of Labelled Compounds and Radiopharmaceuticals
2018 | Journal article
DOI: 10.1002/jlcr.3612
EID:

2-s2.0-85044439568

Part of ISSN: 10991344 03624803
Contributors: Carter, L.M.; Poty, S.; Sharma, S.K.; Lewis, J.S.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

The inverse electron-demand Diels-Alder reaction as a new methodology for the synthesis of <sup>225</sup>Ac-labelled radioimmunoconjugates

Chemical Communications
2018 | Journal article
DOI: 10.1039/c7cc09129j
EID:

2-s2.0-85043476609

Part of ISSN: 1364548X 13597345
Contributors: Poty, S.; Membreno, R.; Glaser, J.M.; Ragupathi, A.; Scholz, W.W.; Zeglis, B.M.; Lewis, J.S.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

α-emitters for radiotherapy: From basic radiochemistry to clinical studies-part 2

Journal of Nuclear Medicine
2018 | Journal article
DOI: 10.2967/jnumed.117.204651
EID:

2-s2.0-85049404512

Part of ISSN: 2159662X 01615505
Contributors: Poty, S.; Francesconi, L.C.; McDevitt, M.R.; Morris, M.J.; Lewis, J.S.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

α-emitters for radiotherapy: From basic radiochemistry to clinical studies—part 1

Journal of Nuclear Medicine
2018 | Journal article
DOI: 10.2967/jnumed.116.186338
EID:

2-s2.0-85048182226

Part of ISSN: 2159662X 01615505
Contributors: Poty, S.; Francesconi, L.C.; McDevitt, M.R.; Morris, M.J.; Lewis, J.S.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

MANOTA: A promising bifunctional chelating agent for copper-64 immunoPET

Dalton Transactions
2017 | Journal article
DOI: 10.1039/c7dt01772c
EID:

2-s2.0-85032626576

Part of ISSN: 14779234 14779226
Contributors: Moreau, M.; Poty, S.; Vrigneaud, J.-M.; Walker, P.; Guillemin, M.; Raguin, O.; Oudot, A.; Bernhard, C.; Goze, C.; Boschetti, F. et al.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

AMD3100: A Versatile Platform for CXCR4 Targeting <sup>68</sup>Ga-Based Radiopharmaceuticals

Bioconjugate Chemistry
2016 | Journal article
DOI: 10.1021/acs.bioconjchem.5b00689
EID:

2-s2.0-84962301508

Part of ISSN: 15204812 10431802
Contributors: Poty, S.; Gourni, E.; Désogère, P.; Boschetti, F.; Goze, C.; Maecke, H.R.; Denat, F.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

MA-NOTMP: A Triazacyclononane Trimethylphosphinate Based Bifunctional Chelator for Gallium Radiolabelling of Biomolecules

ChemMedChem
2015 | Journal article
DOI: 10.1002/cmdc.201500198
EID:

2-s2.0-84940459852

Part of ISSN: 18607187 18607179
Contributors: Poty, S.; Désogère, P.; Šimeček, J.; Bernhard, C.; Goncalves, V.; Goze, C.; Boschetti, F.; Notni, J.; Wester, H.J.; Denat, F.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: Synthesis, anti-HIV-1 evaluation and binding affinities

Dalton Transactions
2015 | Journal article
DOI: 10.1039/c4dt02972k
EID:

2-s2.0-84924308992

Part of ISSN: 14779234 14779226
Contributors: Poty, S.; Désogère, P.; Goze, C.; Boschetti, F.; D'huys, T.; Schols, D.; Cawthorne, C.; Archibald, S.J.; Maëcke, H.R.; Denat, F.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

Efficient synthesis of 1,4,7-triazacyclononane and 1,4,7-triazacyclononane-based bifunctional chelators for bioconjugation

European Journal of Organic Chemistry
2014 | Journal article
DOI: 10.1002/ejoc.201402708
EID:

2-s2.0-84919402424

Part of ISSN: 10990690 1434193X
Contributors: Désogère, P.; Rousselin, Y.; Poty, S.; Bernhard, C.; Goze, C.; Boschetti, F.; Denat, F.
Source: Self-asserted source
Sophie Poty via Scopus - Elsevier

Peer review (5 reviews for 2 publications/grants)

Review activity for Bioconjugate chemistry. (2)
Review activity for Molecular imaging and biology (3)
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