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Center for Iron Disorders
UCLA Pasarow Mass Spectrometry Laboratory

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Loop profile: 1328891

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Employment (2)

Pure Biologics (Poland): Wrocław, Lower Silesia, PL

2019-07-15 to present | Expert (Cell Biology)
Employment
Source: Self-asserted source
PIOTR RUCHALA

David Geffen School of Medicine at UCLA: Los Angeles, California, US

2006-02-15 to present
Employment
Source: Self-asserted source
PIOTR RUCHALA

Works (50 of 61)

Items per page:
Page 1 of 2

Maternal hepcidin determines embryo iron homeostasis in mice

Blood
2020-11-05 | Journal article
DOI: 10.1182/blood.2020005745
Contributors: Veena Sangkhae; Allison L. Fisher; Kristine J. Chua; Piotr Ruchala; Tomas Ganz; Elizabeta Nemeth
Source: check_circle
Crossref

Insights into the structure and molecular topography of the fatty acylated domain of synaptotagmin-1

Biochimica et biophysica acta. Biomembranes
2019 | Journal article
DOI: 10.1016/j.bbamem.2018.12.019
Source: Self-asserted source
PIOTR RUCHALA

Quantitative Measure of Intestinal Permeability Using Blue Food Coloring

The Journal of surgical research
2019 | Journal article
DOI: 10.1016/j.jss.2018.07.005
Source: Self-asserted source
PIOTR RUCHALA
grade
Preferred source (of 2)‎

The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation

Radiation research
2019 | Journal article
DOI: 10.1667/rr15231.1
Source: Self-asserted source
PIOTR RUCHALA

Optimization of 1,3-disubstituted urea-based inhibitors of Zika virus infection

Bioorganic & Medicinal Chemistry Letters
2019-10 | Journal article
DOI: 10.1016/j.bmcl.2019.126626
Contributors: Ronik Khachatoorian; Ewa D. Micewicz; Alina Micewicz; Samuel W. French; Piotr Ruchala
Source: check_circle
Crossref

Position of lipidation influences anticancer activity of Smac analogs

Bioorganic & Medicinal Chemistry Letters
2019-04 | Journal article
DOI: 10.1016/j.bmcl.2019.04.041
Contributors: Ewa D. Micewicz; Christine Nguyen; Alina Micewicz; Alan J. Waring; William H. McBride; Piotr Ruchala
Source: check_circle
Crossref

Conformation and Trimer Association of the Transmembrane Domain of the Parainfluenza Virus Fusion Protein in Lipid Bilayers from Solid-State NMR: Insights into the Sequence Determinants of Trimer Structure and Fusion Activity

Journal of molecular biology
2018 | Journal article
DOI: 10.1016/j.jmb.2018.01.002
Source: Self-asserted source
PIOTR RUCHALA

Hepcidin Protects against Lethal Escherichia coli Sepsis in Mice Inoculated with Isolates from Septic Patients

Infection and immunity
2018 | Journal article
DOI: 10.1128/IAI.00253-18
Source: Self-asserted source
PIOTR RUCHALA

Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models

Gastroenterology
2018 | Journal article
DOI: 10.1053/j.gastro.2017.10.012
Source: Self-asserted source
PIOTR RUCHALA
grade
Preferred source (of 2)‎

4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues

PloS one
2017 | Journal article
DOI: 10.1371/journal.pone.0181577
Source: Self-asserted source
PIOTR RUCHALA

Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron

Blood
2017 | Journal article
DOI: 10.1182/blood-2017-03-772715
Source: Self-asserted source
PIOTR RUCHALA

Hepcidin knockout mice spontaneously develop chronic pancreatitis owing to cytoplasmic iron overload in acinar cells

The Journal of pathology
2017 | Journal article
DOI: 10.1002/path.4822
Source: Self-asserted source
PIOTR RUCHALA

Identification of novel small-molecule inhibitors of Zika virus infection

Bioorganic & medicinal chemistry letters
2017 | Journal article
DOI: 10.1016/j.bmcl.2017.12.019
Source: Self-asserted source
PIOTR RUCHALA
grade
Preferred source (of 2)‎

Allosteric heat shock protein 70 inhibitors block hepatitis C virus assembly

International journal of antimicrobial agents
2016 | Journal article
DOI: 10.1016/j.ijantimicag.2016.01.012
Source: Self-asserted source
PIOTR RUCHALA

Bridged Analogues for p53-Dependent Cancer Therapy Obtained by S-Alkylation

International journal of peptide research and therapeutics
2016 | Journal article
DOI: 10.1007/s10989-015-9487-3
Source: Self-asserted source
PIOTR RUCHALA

Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus

Cell host & microbe
2015 | Journal article
DOI: 10.1016/j.chom.2014.12.001
Source: Self-asserted source
PIOTR RUCHALA

Lipid-conjugated Smac analogues

Bioorganic & medicinal chemistry letters
2015 | Journal article
DOI: 10.1016/j.bmcl.2015.09.017
Source: Self-asserted source
PIOTR RUCHALA

Small cyclic agonists of iron regulatory hormone hepcidin

Bioorganic & medicinal chemistry letters
2015 | Journal article
DOI: 10.1016/j.bmcl.2015.03.012
Source: Self-asserted source
PIOTR RUCHALA

Small lipidated anti-obesity compounds derived from neuromedin U

European journal of medicinal chemistry
2015 | Journal article
DOI: 10.1016/j.ejmech.2015.07.020
Source: Self-asserted source
PIOTR RUCHALA

Structural characterization of the HSP70 interaction domain of the hepatitis C viral protein NS5A

Virology
2015 | Journal article
DOI: 10.1016/j.virol.2014.10.011
Source: Self-asserted source
PIOTR RUCHALA

Thiol-derivatized minihepcidins retain biological activity

Bioorganic & medicinal chemistry letters
2015 | Journal article
DOI: 10.1016/j.bmcl.2014.12.094
Source: Self-asserted source
PIOTR RUCHALA

Uncovering the Mechanism of Aggregation of Human Transthyretin

The Journal of biological chemistry
2015 | Journal article
DOI: 10.1074/jbc.M115.659912
Source: Self-asserted source
PIOTR RUCHALA

Novel dimeric Smac analogs as prospective anticancer agents

Bioorganic & medicinal chemistry letters
2014 | Journal article
DOI: 10.1016/j.bmcl.2014.02.024
Source: Self-asserted source
PIOTR RUCHALA

Surfactant protein C peptides with salt-bridges ("ion-locks") promote high surfactant activities by mimicking the α-helix and membrane topography of the native protein

PeerJ
2014 | Journal article
DOI: 10.7717/peerj.485
Source: Self-asserted source
PIOTR RUCHALA

The pathophysiology and pharmacology of hepcidin

Trends in pharmacological sciences
2014 | Journal article
DOI: 10.1016/j.tips.2014.01.004
Source: Self-asserted source
PIOTR RUCHALA

A compensatory mutation provides resistance to disparate HIV fusion inhibitor peptides and enhances membrane fusion

PloS one
2013 | Journal article
DOI: 10.1371/journal.pone.0055478
Source: Self-asserted source
PIOTR RUCHALA

Inhibitors of HIV-1 entry

Current pharmaceutical design
2013 | Journal article
DOI: 10.2174/1381612811319100003
Source: Self-asserted source
PIOTR RUCHALA

A cell-permeable hairpin peptide inhibits hepatitis C viral nonstructural protein 5A-mediated translation and virus production

Hepatology (Baltimore, Md.)
2012 | Journal article
DOI: 10.1002/hep.25533
Source: Self-asserted source
PIOTR RUCHALA

Hapivirins and diprovirins: novel θ-defensin analogs with potent activity against influenza A virus

Journal of immunology (Baltimore, Md. : 1950)
2012 | Journal article
DOI: 10.4049/jimmunol.1101335
Source: Self-asserted source
PIOTR RUCHALA

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

Blood
2012 | Journal article
DOI: 10.1182/blood-2012-07-440743
Source: Self-asserted source
PIOTR RUCHALA

Stable, compact, bright biofunctional quantum dots with improved peptide coating

The journal of physical chemistry. B
2012 | Journal article
DOI: 10.1021/jp306453y
Source: Self-asserted source
PIOTR RUCHALA

Context mediates antimicrobial efficacy of kinocidin congener peptide RP-1

PloS one
2011 | Journal article
DOI: 10.1371/journal.pone.0026727
Source: Self-asserted source
PIOTR RUCHALA

Humanized theta-defensins (retrocyclins) enhance macrophage performance and protect mice from experimental anthrax infections

Antimicrobial agents and chemotherapy
2011 | Journal article
DOI: 10.1128/AAC.00267-11
Source: Self-asserted source
PIOTR RUCHALA

KLâ‚„ peptide induces reversible collapse structures on multiple length scales in model lung surfactant

Biophysical journal
2011 | Journal article
DOI: 10.1016/j.bpj.2011.10.050
Source: Self-asserted source
PIOTR RUCHALA

Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload

The Journal of clinical investigation
2011 | Journal article
DOI: 10.1172/JCI57693
Source: Self-asserted source
PIOTR RUCHALA

Structures of β-hairpin antimicrobial protegrin peptides in lipopolysaccharide membranes: mechanism of gram selectivity obtained from solid-state nuclear magnetic resonance

Biochemistry
2011 | Journal article
DOI: 10.1021/bi101975v
Source: Self-asserted source
PIOTR RUCHALA

Simplified θ-Defensins: Search for New Antivirals

2011-12 | Journal article
DOI: 10.1007/s10989-011-9272-x
Part of ISSN: 1573-3149
Part of ISSN: 1573-3904
Source: Self-asserted source
PIOTR RUCHALA

Small Azurin Derived Peptide Targets Ephrin Receptors for Radiotherapy

2011-09 | Journal article
DOI: 10.1007/s10989-011-9265-9
Part of ISSN: 1573-3149
Part of ISSN: 1573-3904
Source: Self-asserted source
PIOTR RUCHALA

Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs

PloS one
2010 | Journal article
DOI: 10.1371/journal.pone.0008672
Source: Self-asserted source
PIOTR RUCHALA

Functional importance of the NH2-terminal insertion sequence of lung surfactant protein B

American journal of physiology. Lung cellular and molecular physiology
2010 | Journal article
DOI: 10.1152/ajplung.00190.2009
Source: Self-asserted source
PIOTR RUCHALA

Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin

PloS one
2010 | Journal article
DOI: 10.1371/journal.pone.0014360
Source: Self-asserted source
PIOTR RUCHALA

Membrane-bound dynamic structure of an arginine-rich cell-penetrating peptide, the protein transduction domain of HIV TAT, from solid-state NMR

Biochemistry
2010 | Journal article
DOI: 10.1021/bi100642n
Source: Self-asserted source
PIOTR RUCHALA

Oxpholipin 11D: an anti-inflammatory peptide that binds cholesterol and oxidized phospholipids

PloS one
2010 | Journal article
DOI: 10.1371/journal.pone.0010181
Source: Self-asserted source
PIOTR RUCHALA

The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques

PloS one
2010 | Journal article
DOI: 10.1371/journal.pone.0015111
Source: Self-asserted source
PIOTR RUCHALA

A novel method for oral delivery of apolipoprotein mimetic peptides synthesized from all L-amino acids

Journal of lipid research
2009 | Journal article
DOI: 10.1194/jlr.M800539-JLR200
Source: Self-asserted source
PIOTR RUCHALA

A peptide hairpin inhibitor of amyloid beta-protein oligomerization and fibrillogenesis

Biochemistry
2009 | Journal article
DOI: 10.1021/bi901325g
Source: Self-asserted source
PIOTR RUCHALA

Antimicrobial host defense peptides in an arteriviral infection: differential peptide expression and virus inactivation

Viral immunology
2009 | Journal article
DOI: 10.1089/vim.2009.0005
Source: Self-asserted source
PIOTR RUCHALA

Human alpha-defensins inhibit hemolysis mediated by cholesterol-dependent cytolysins

Infection and immunity
2009 | Journal article
DOI: 10.1128/IAI.00232-09
Source: Self-asserted source
PIOTR RUCHALA

Interactions of alpha-, beta-, and theta-defensins with influenza A virus and surfactant protein D

Journal of immunology (Baltimore, Md. : 1950)
2009 | Journal article
DOI: 10.4049/jimmunol.0804049
Source: Self-asserted source
PIOTR RUCHALA

Multivalent binding of carbohydrates by the human alpha-defensin, HD5

Journal of immunology (Baltimore, Md. : 1950)
2009 | Journal article
DOI: 10.4049/jimmunol.0900244
Source: Self-asserted source
PIOTR RUCHALA
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