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Employment (1)

Washington University School of Medicine in St. Louis: MO, MO, US

2018-07-01 to present | Assistant Professor (Medicine/Oncology)
Employment
Source: Self-asserted source
Jaebok Choi

Education and qualifications (1)

Baylor College of Medicine: Houston, TX, US

Education
Source: Self-asserted source
Jaebok Choi

Funding (1)

Baricitinib-induced blockade of JAK1/2 and PKN1 to control GvHD and GvL

2023-07-01 to 2027-06-30 | Grant
American Cancer Society (Atlanta, US)
GRANT_NUMBER:

RSG-23-1031286-01-IBCD

Source: check_circle
American Cancer Society - ProposalCentral

Works (39)

Itacitinib for Prevention of Graft-Versus-Host Disease and Cytokine Release Syndrome in Haploidentical Transplantation

Blood Journal
2024-11-22 | Journal article
Contributors: Ramzi Abboud; Mark A. Schroeder; Michael P Rettig; Reyka G Jayasinghe; Feng Gao; Jeremy Eisele; Leah Gehrs; Julie K. Ritchey; Jaebok Choi; Camille N Abboud et al.
Source: check_circle
Crossref

HSPA9/mortalin inhibition disrupts erythroid maturation through a TP53-dependent mechanism in human CD34+ hematopoietic progenitor cells

Cell Stress and Chaperones
2024-04 | Journal article
Part of ISSN: 1355-8145
Contributors: Christopher Butler; Morgan Dunmire; Jaebok Choi; Gabor Szalai; Anissa Johnson; Wei Lei; Xin Chen; Liang Liu; Wei Li; Matthew J. Walter et al.
Source: Self-asserted source
Jaebok Choi

Novel JAK Inhibitors to Reduce Graft-Versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation in a Preclinical Mouse Model

Molecules
2024-04-16 | Journal article
Contributors: Sena Kim; Peter Ruminski; Megh Singh; Karl Staser; Kidist Ashami; Julie Ritchey; Sora Lim; John F. DiPersio; Jaebok Choi
Source: check_circle
Crossref
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Preferred source (of 2)‎

Phase I-II Trial of Early Azacitidine after Matched Unrelated Donor Hematopoietic Cell Transplantation

Transplantation and Cellular Therapy
2023-11 | Journal article
Contributors: Ziheng Xu; Jaebok Choi; Matthew Cooper; Jeffrey King; Mark A. Fiala; Jingxia Liu; Iskra Pusic; Rizwan Romee; Amanda Cashen; Meagan A. Jacoby et al.
Source: check_circle
Crossref

Baricitinib with cyclosporine eliminates acute graft rejection in fully mismatched skin and heart transplant models

Frontiers in Immunology
2023-09-06 | Journal article
Part of ISSN: 1664-3224
Contributors: Ramzi Abboud; Sena Kim; Karl Staser; Reyka G. Jayasinghe; Sora Lim; Parmeshwar Amatya; C. Corbin Frye; Benjamin Kopecky; Julie Ritchey; Feng Gao et al.
Source: Self-asserted source
Jaebok Choi

S100A8 and S100A9 in Hematologic Malignancies: From Development to Therapy

International Journal of Molecular Sciences
2023-08 | Journal article | Author
Contributors: Farnaz Razmkhah; Sena Kim; Sora Lim; Abdul-Jalil Dania; Jaebok Choi
Source: check_circle
Multidisciplinary Digital Publishing Institute

Overexpression of S100A9 in donor T cells is associated with reconstitution of gut microbiota and outcome of allogeneic hematopoietic stem cell transplantation

Blood Research
2023-06-30 | Journal article
Part of ISSN: 2287-979X
Part of ISSN: 2288-0011
Contributors: Sena Kim; Sora Lim; Farnaz Razmkhah; Jaebok Choi
Source: Self-asserted source
Jaebok Choi

A Multicenter Phase 2 Clinical Trial of 10-Day Decitabine, Dose-Escalated Donor Lymphocyte Infusion, and Ruxolitinib for Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes after Allogeneic Hematopoietic Cell Transplantation

Transplantation and Cellular Therapy
2023-05 | Journal article
Contributors: Armin Rashidi; Eric J. Huselton; Heather E. Stefanski; Todd E. DeFor; Ryan Shanley; Jaebok Choi; John F. DiPersio; Mark Juckett; Jeffrey S. Miller; Daniel J. Weisdorf et al.
Source: check_circle
Crossref

The adrenal stress response is an essential host response against therapy-induced lethal immune activation

Science Signaling
2023-03-21 | Journal article
Contributors: Ling Guo; Weinan Wang; Qian Wang; Dan Hao; Misa Ito; Bin Huang; Chieko Mineo; Philip W. Shaul; Jaebok Choi; L. Frank Huang et al.
Source: check_circle
Crossref

S100A9 upregulated by IFNGR signaling blockade functions as a novel GVHD suppressor without compromising GVL in mice

Blood
2023-02-23 | Journal article | Author
Part of ISSN: 0006-4971
Part of ISSN: 1528-0020
Contributors: Sena Kim; Sora Lim; Boram Kim; Julie Ritchey; Kiran Vij; Julie Prior; Lynne Marsala; Alyssa Stoner; Feng Gao; Samuel Achilefu et al.
Source: Self-asserted source
Jaebok Choi

Restoring NK cell functions in AML relapse

Blood
2022-12-29 | Journal article
Contributors: Sena Kim; Jaebok Choi
Source: check_circle
Crossref

Editorial: Interferons and GvHD

Frontiers in Immunology
2022-02-03 | Journal article
Part of ISSN: 1664-3224
Contributors: Boram Kim; Jaebok Choi
Source: Self-asserted source
Jaebok Choi

Baricitinib prevents GvHD by increasing Tregs via JAK3 and treats established GvHD by promoting intestinal tissue repair via EGFR

Leukemia
2022-01 | Journal article | Author
Part of ISSN: 0887-6924
Part of ISSN: 1476-5551
Contributors: Sena Kim; Kidist Ashami; Sora Lim; Karl Staser; Kiran Vij; Srikanth Santhanam; Julie Ritchey; Sarah Peterson; Feng Gao; Matthew Ciorba et al.
Source: Self-asserted source
Jaebok Choi

Mouse models of graft-versus-host disease

Methods in Cell Biology
2022-01-17 | Book chapter
Part of ISSN: 0091-679X
Contributors: Dilan A. Patel; Mark A. Schroeder; Jaebok Choi; John F. DiPersio
Source: Self-asserted source
Jaebok Choi

Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation

Journal of Clinical Investigation
2021-12-15 | Journal article
Contributors: Stephen P. Persaud; Julie K. Ritchey; Sena Kim; Sora Lim; Peter G. Ruminski; Matthew L. Cooper; Michael P. Rettig; Jaebok Choi; John F. DiPersio
Source: check_circle
Crossref

Selective targeting of α4β1 integrin attenuates murine graft versus host disease

Leukemia
2020-11-09 | Journal article
Contributors: Bader Alahmari; Matthew L. Cooper; Kiran Vij; Julie Ritchey; Peter Ruminski; Feng Gao; Jaebok Choi; John F. DiPersio
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Targeting Histone Deacetylases to Modulate Graft-Versus-Host Disease and Graft-Versus-Leukemia

International Journal of Molecular Sciences
2020-06-16 | Journal article
Contributors: Sena Kim; Srikanth Santhanam; Sora Lim; Jaebok Choi
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease

Blood Advances
2020-04-28 | Journal article
Contributors: Mark A. Schroeder; H. Jean Khoury; Madan Jagasia; Haris Ali; Gary J. Schiller; Karl Staser; Jaebok Choi; Leah Gehrs; Michael C. Arbushites; Ying Yan et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

An “off-the-shelf” fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies

Leukemia
2018 | Journal article
EID:

2-s2.0-85042538593

Contributors: Cooper, M.L.; Choi, J.; Staser, K.; Ritchey, J.K.; Devenport, J.M.; Eckardt, K.; Rettig, M.P.; Wang, B.; Eissenberg, L.G.; Ghobadi, A. et al.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier
grade
Preferred source (of 2)‎

Erratum: Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance (Immunity (2018) 48(5) (923–936.e4) (S1074761318301444) (10.1016/j.immuni.2018.04.007))

Immunity
2018 | Journal article
EID:

2-s2.0-85047853769

Part of ISBN:

10974180 10747613

Contributors: Perry, J.S.A.; Russler-Germain, E.V.; Zhou, Y.W.; Purtha, W.; Cooper, M.L.; Choi, J.; Schroeder, M.A.; Salazar, V.; Egawa, T.; Lee, B.-C. et al.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

OMIP-042: 21-color flow cytometry to comprehensively immunophenotype major lymphocyte and myeloid subsets in human peripheral blood

Cytometry Part A
2018 | Journal article
EID:

2-s2.0-85039731185

Contributors: Staser, K.W.; Eades, W.; Choi, J.; Karpova, D.; DiPersio, J.F.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

Targeting IFNGR/IL6R or downstream JAK1/JAK2 to control GvHD

Oncotarget
2018 | Journal article
EID:

2-s2.0-85056132583

Part of ISBN:

19492553

Contributors: Ashami, K.; DiPersio, J.F.; Choi, J.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

The Role of Janus Kinase Signaling in Graft-Versus-Host Disease and Graft Versus Leukemia

Biology of Blood and Marrow Transplantation
2018 | Journal article
EID:

2-s2.0-85041575254

Contributors: Schroeder, M.A.; Choi, J.; Staser, K.; DiPersio, J.F.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation.

PloS one
2018-11-19 | Journal article
Source: Self-asserted source
Jaebok Choi
grade
Preferred source (of 2)‎

Targeting IFNGR/IL6R or downstream JAK1/JAK2 to control GvHD.

Oncotarget
2018-11-06 | Journal article
Source: Self-asserted source
Jaebok Choi

Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance.

Immunity
2018-05-08 | Journal article
Source: Self-asserted source
Jaebok Choi
grade
Preferred source (of 2)‎

Baricitinib-induced blockade of interferon gamma receptor and interleukin-6 receptor for the prevention and treatment of graft-versus-host disease.

Leukemia
2018-04-02 | Journal article
Source: Self-asserted source
Jaebok Choi
grade
Preferred source (of 3)‎

Azacitidine mitigates graft-versus-host disease via differential effects on the proliferation of T effectors and natural regulatory T cells in vivo

Journal of Immunology
2017 | Journal article
EID:

2-s2.0-85018472373

Contributors: Cooper, M.L.; Choi, J.; Karpova, D.; Vij, K.; Ritchey, J.; Schroeder, M.A.; DiPersio, J.F.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier
grade
Preferred source (of 2)‎

Phase I study of azacitidine following donor lymphocyte infusion for relapsed acute myeloid leukemia post allogeneic stem cell transplantation

Leukemia Research
2016 | Journal article
EID:

2-s2.0-84980587480

Contributors: Ghobadi, A.; Choi, J.; Fiala, M.A.; Fletcher, T.; Liu, J.; Eissenberg, L.G.; Abboud, C.; Cashen, A.; Vij, R.; Schroeder, M.A. et al.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

GPR18 controls reconstitution of mouse small intestine intraepithelial lymphocytes following bone marrow transplantation

PLoS ONE
2015 | Journal article
EID:

2-s2.0-84941248952

Contributors: Becker, A.M.; Callahan, D.J.; Richner, J.M.; Choi, J.; DiPersio, J.F.; Diamond, M.S.; Bhattacharya, D.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome

Biology of Blood and Marrow Transplantation
2015 | Journal article
EID:

2-s2.0-84941317871

Contributors: Pusic, I.; Choi, J.; Fiala, M.A.; Gao, F.; Holt, M.; Cashen, A.F.; Vij, R.; Abboud, C.N.; Stockerl-Goldstein, K.E.; Jacoby, M.A. et al.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

Effect of epigallocatechin-3-gallate on graft-versus-host disease

Cell Transplantation
2014 | Journal article
EID:

2-s2.0-84906957836

Contributors: Choi, J.; Cooper, M.L.; Ziga, E.D.; Ritchey, J.; DiPersio, J.F.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

Pharmacologic blockade of JAK1/JAK2 reduces GvHD and preserves the graft-versus-leukemia effect

PLoS ONE
2014 | Journal article
EID:

2-s2.0-84907829534

Contributors: Choi, J.; Cooper, M.L.; Alahmari, B.; Ritchey, J.; Collins, L.; Holt, M.; DiPersio, J.F.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

F11R Is a Novel Monocyte Prognostic Biomarker for Malignant Glioma

PLoS ONE
2013 | Journal article
EID:

2-s2.0-84885411121

Contributors: Pong, W.W.; Walker, J.; Wylie, T.; Magrini, V.; Luo, J.; Emnett, R.J.; Choi, J.; Cooper, M.L.; Griffith, M.; Griffith, O.L. et al.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

IFNγR signaling mediates alloreactive T-cell trafficking and GVHD

Blood
2012 | Journal article
EID:

2-s2.0-84868606215

Contributors: Choi, J.; Ziga, E.D.; Ritchey, J.; Collins, L.; Prior, J.L.; Cooper, M.L.; Piwnica-Worms, D.; DiPersio, J.F.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia

Blood
2010 | Journal article
EID:

2-s2.0-77955900102

Contributors: Choi, J.; Ritchey, J.; Prior, J.L.; Holt, M.; Shannon, W.D.; Deych, E.; Piwnica-Worms, D.R.; DiPersio, J.F.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

AFF-1, a FOS-1-Regulated Fusogen, Mediates Fusion of the Anchor Cell in C. elegans

Developmental Cell
2007 | Journal article
EID:

2-s2.0-34247568597

Contributors: Sapir, A.; Choi, J.; Leikina, E.; Avinoam, O.; Valansi, C.; Chernomordik, L.V.; Newman, A.P.; Podbilewicz, B.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

A two-promoter system of gene expression in C. elegans

Developmental Biology
2006 | Journal article
EID:

2-s2.0-33747073534

Contributors: Choi, J.; Newman, A.P.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

N-ethylmaleimide sensitive factor is required for fusion of the C. elegans uterine anchor cell

Developmental Biology
2006 | Journal article
EID:

2-s2.0-33748202591

Contributors: Choi, J.; Richards, K.L.; Cinar, H.N.; Newman, A.P.
Source: Self-asserted source
Jaebok Choi via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Cytotherapy. (1)