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Scopus Author ID: 57212228340

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Employment (2)

Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation: Hualien, TW

2022-08-01 to present | PostDoc (Cardiovascular and Mitochondrial Related Disease Research Center)
Employment
Source: Self-asserted source
Bruce Chi-Kang Tsai

Hualien Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation: Hualien, TW

2020-12-01 to 2022-01-31 | PostDoc (Cardiovascular and Mitochondrial Related Disease Research Center)
Employment
Source: Self-asserted source
Bruce Chi-Kang Tsai

Education and qualifications (3)

China Medical University: Taichung, TW

2017-08-01 to 2020-10-31 | Ph.D. Program for Aging (Full Time)
Education
Source: Self-asserted source
Bruce Chi-Kang Tsai

Australian National University: ACT, ACT, AU

2010-08-01 to 2012-07-31 | Master of Biotechnology by Research (Full Time)
Education
Source: Self-asserted source
Bruce Chi-Kang Tsai

National Chung Hsing University: Taichung, TW

2005-08-01 to 2008-07-31 | Master of Science in Biotechnology (Full Time)
Education
Source: Self-asserted source
Bruce Chi-Kang Tsai

Works (33)

Hepatocellular Carcinoma Cells in Humans Exhibit Resistance to Suberoylanilide Hydroxamic Acid (SAHA) Owing to the Diminished Level of Hsa‐miR‐125a‐5p

Chemical Biology & Drug Design
2025-01 | Journal article
DOI: 10.1111/cbdd.70040
Contributors: Shih‐Wen Kao; Wei‐Wen Kuo; Bruce Chi‐Kang Tsai; Ebro Chawesa Mwakalinga; Thomas Gabriel Mhone; Ming‐Cheng Chen; Chia‐Hua Kuo; Yi‐Sheng Liu; Shinn‐Zong Lin; Chih‐Yang Huang
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Crossref

Low-concentration imiquimod treatment promotes enhanced skin barrier functions through epidermal melanization reaction regulation

Environmental Toxicology
2024 | Journal article
DOI: 10.1002/tox.24332
EID:

2-s2.0-85193312797

Part of ISSN: 15227278 15204081
Contributors: Lin, T.-K.; Tsai, C.-L.; Tsai, B.C.-K.; Kuo, C.-H.; Ho, T.-J.; Hsieh, D.J.-Y.; Kuo, W.-W.; Huang, C.-Y.
Source: Self-asserted source
Bruce Chi-Kang Tsai via Scopus - Elsevier
grade
Preferred source (of 2)‎

Novel chromium (III)-based compound for inhibition of oxaliplatin-resistant colorectal cancer progression

American Journal of Cancer Research
2024 | Journal article
WOSUID: WOS:001195687900006
Contributors: Chen, Ming-Cheng; Devi, Hema Sri; Pien, Hsueh-Fa; Wen, Shina Fong-Mei; Sheu, Jenn-Line; Tsai, Bruce Chi-Kang; Huang, Chih-Yang; Lin, Yu -Jung
Source: check_circle
Web of Science Researcher Profile Sync

Platycodi radix aqueous extract salvages doxorubicin-induced senescence by mitochondrial reactive oxygen species reduction in umbilical cord matrix stem cells

Environmental Toxicology
2024 | Journal article
DOI: 10.1002/tox.24240
EID:

2-s2.0-85189622763

Part of ISSN: 15227278 15204081
Contributors: Lee, P.-Y.; Sitorus, M.A.; Kuo, C.-H.; Tsai, B.C.-K.; Kuo, W.-W.; Lin, K.-H.; Lu, S.-Y.; Lin, Y.-M.; Ho, T.-J.; Huang, C.-Y.
Source: Self-asserted source
Bruce Chi-Kang Tsai via Scopus - Elsevier
grade
Preferred source (of 3)‎

Tannic Acid Impedes the Proliferation of Bladder Cancer Cells by Elevating Mitochondrial Pathways of Apoptosis

Cell Biochemistry and Biophysics
2024 | Journal article
DOI: 10.1007/s12013-024-01286-w
EID:

2-s2.0-85194753761

Part of ISSN: 15590283 10859195
Contributors: Li, C.-C.; Tsai, B.C.-K.; Annseles Rajula, S.; Hsu, C.-H.; Chen, M.-C.; Kuo, C.-H.; Yeh, C.-M.; Hsieh, D.J.-Y.; Kuo, W.-W.; Huang, C.-Y.
Source: Self-asserted source
Bruce Chi-Kang Tsai via Scopus - Elsevier
grade
Preferred source (of 2)‎

Enhanced IGF‐IIRα Expression Exacerbates Lipopolysaccharide‐Induced Cardiac Inflammation, Hypertrophy, and Apoptosis Through Calcineurin Activation

Environmental Toxicology
2024-11 | Journal article
DOI: 10.1002/tox.24385
Contributors: Khwanchit Boonha; Wei‐Wen Kuo; Bruce Chi‐Kang Tsai; Dennis Jine‐Yuan Hsieh; Kuan‐Ho Lin; Shang‐Yeh Lu; Chia‐Hua Kuo; Liang‐Yo Yang; Chih‐Yang Huang
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Crossref
grade
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Rhodiola and Salidroside Attenuate Oxidative Stress‐Triggered H9c2 Cardiomyoblast Apoptosis Through IGF1R‐Induced ERK1/2 Activation

Environmental Toxicology
2024-11 | Journal article
DOI: 10.1002/tox.24372
Contributors: I‐Ju Ju; Bruce Chi‐Kang Tsai; Wei‐Wen Kuo; Chia‐Hua Kuo; Yueh‐Min Lin; Dennis Jine‐Yuan Hsieh; Pei‐Ying Pai; Shang‐En Huang; Shang‐Yeh Lu; Shin‐Da Lee et al.
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Crossref
grade
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Ohwia caudata aqueous extract attenuates senescence in aging adipose-derived mesenchymal stem cells

Heliyon
2024-05 | Journal article
DOI: 10.1016/j.heliyon.2024.e29729
Part of ISSN: 2405-8440
Contributors: Tsung-Jung Ho; Bruce Chi-Kang Tsai; Goswami Debakshee; Marthandam Asokan Shibu; Chia-Hua Kuo; Chih-Hsueh Lin; Pi-Yu Lin; Shinn-Zong Lin; Wei-Wen Kuo; Chih-Yang Huang
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Calycosin Enhances Heat Shock Related-Proteins in H9c2 Cells to Modulate Survival and Apoptosis against Heat Shock

The American Journal of Chinese Medicine
2024-01 | Journal article
DOI: 10.1142/S0192415X24500472
Contributors: Pei-Fang Lai; Ramasamy Mahendran; Bruce Chi-Kang Tsai; Cheng-You Lu; Chia-Hua Kuo; Kuan-Ho Lin; Shang-Yeh Lu; Yu-Ling Wu; Yung-Ming Chang; Wei-Wen Kuo et al.
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Crossref
grade
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Alcoholic Hericium erinaceus mycelia extract induces SIRT-1/ERK-1/2 mediated autophagy to prevent accumulation and spreading of alpha-synuclein and amyloid-beta peptide on the A53T transgenic mice

Journal of Functional Foods
2023-11 | Journal article
DOI: 10.1016/j.jff.2023.105874
Part of ISSN: 1756-4646
Contributors: Yu-Jung Lin; Chih-Yang Huang; Bruce Chi-Kang Tsai; Kannan Ashok Kumar; Dennis Jine-Yuan Hsieh; Ping-Ling Chiu; Yung-Ming Chang; Tsung-Jung Ho; Wei-Wen Kuo; Da-Tong Ju
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Anethole mitigates H2O2‐induced inflammation in HIG‐82 synoviocytes by suppressing the aquaporin 1 expression and activating the protein kinase A pathway

Environmental Toxicology
2023-11-21 | Journal article
DOI: 10.1002/tox.24023
Part of ISSN: 1520-4081
Part of ISSN: 1522-7278
Contributors: Tai‐Lung Huang; Yu‐Chun Chang; Bruce Chi‐Kang Tsai; Tung‐Sheng Chen; Shih‐Wen Kao; Yung‐Yun Tsai; Shinn‐Zong Lin; Chun‐Hsu Yao; Kuan‐Ho Lin; Wei-Wen Kuo et al.
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Development and evaluation of a novel chromium III-based compound for potential inhibition of emerging SARS-CoV-2 variants

Heliyon
2023-09 | Journal article
DOI: 10.1016/j.heliyon.2023.e20011
Part of ISSN: 2405-8440
Contributors: Yu-Jung Lin; Navaneethan Sundhar; Hema Sri Devi; Hsueh-Fa Pien; Shina Fong-Mei Wen; Jenn-Line Sheu; Bruce Chi-Kang Tsai; Chih-Yang Huang
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Human adipose-derived stem cells preconditioned with a novel herbal formulation Jing Shi attenuate doxorubicin-induced cardiac damage

Aging
2023-09-15 | Journal article
DOI: 10.18632/aging.205026
EID:

2-s2.0-85171900715

Part of ISSN: 19454589
WOSUID: WOS:001120064300036
Contributors: Dennis Jine-Yuan Hsieh; Bruce Chi-Kang Tsai; Parthasarathi Barik; Marthandam Asokan Shibu; Chia-Hua Kuo; Wei-Wen Kuo; Pi-Yu Lin; Cheng-Yen Shih; Shinn-Zong Lin; Tsung-Jung Ho et al.
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer’s Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways

Neurotoxicity Research
2023-09-14 | Journal article
DOI: 10.1007/s12640-023-00666-z
Part of ISSN: 1029-8428
Part of ISSN: 1476-3524
Contributors: Da-Tong Ju; Rwei-Fen S. Huang; Bruce Chi-Kang Tsai; Yi-Chen Su; Ping-Ling Chiu; Yung-Ming Chang; V. Vijaya Padma; Tsung-Jung Ho; Chun-Hsu Yao; Wei-Wen Kuo et al.
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Ligustrazine improves the compensative effect of Akt survival signaling to protect liver Kupffer cells in trauma‐hemorrhagic shock rats

Chemical Biology & Drug Design
2023-08-23 | Journal article
DOI: 10.1111/cbdd.14327
Part of ISSN: 1747-0277
Part of ISSN: 1747-0285
Contributors: Ray‐Jade Chen; Ming‐Cheng Chen; Bruce Chi‐Kang Tsai; Rakesh Roy; Yi‐Ru Chang; Tso‐Fu Wang; Wei‐Wen Kuo; Chia‐Hua Kuo; Chun‐Hsu Yao; Chi‐Cheng Li et al.
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

<scp><i>Ohwia caudata</i></scp> aqueous extract attenuates doxorubicin‐induced mitochondrial dysfunction in <scp>Wharton</scp>'s jelly‐derived mesenchymal stem cells

Environmental Toxicology
2023-07-17 | Journal article
DOI: 10.1002/tox.23880
Part of ISSN: 1520-4081
Part of ISSN: 1522-7278
Contributors: Pei‐Ying Lee; Bruce Chi‐Kang Tsai; Maria Angelina Sitorus; Pi‐Yu Lin; Shinn‐Zong Lin; Cheng‐Yen Shih; Shang‐Yeh Lu; Yueh‐Min Lin; Tsung‐Jung Ho; Chih-Yang Huang
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Cardiac-specific overexpression of insulin-like growth factor II receptor-α interferes with the regulation of calcium homeostasis in the heart under hyperglycemic conditions

Molecular Biology Reports
2023-05 | Journal article
DOI: 10.1007/s11033-023-08327-2
Part of ISSN: 0301-4851
Part of ISSN: 1573-4978
Contributors: Shang-Yeh Lu; Bruce Chi-Kang Tsai; Dao Van Thao; Chin-Hu Lai; Michael Yu-Chih Chen; Wei-Wen Kuo; Chia-Hua Kuo; Kuan-Ho Lin; Dennis Jine-Yuan Hsieh; Chih-Yang Huang
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Insulin‐like growth factor II receptor alpha overexpression in heart aggravates hyperglycemia‐induced cardiac inflammation and myocardial necrosis

Environmental Toxicology
2023-03 | Journal article
DOI: 10.1002/tox.23717
Part of ISSN: 1520-4081
Part of ISSN: 1522-7278
Contributors: Chin‐Hu Lai; Dao Van Thao; Bruce Chi‐Kang Tsai; Dennis Jine‐Yuan Hsieh; Michael Yu‐Chih Chen; Wei-Wen Kuo; Chia‐Hua Kuo; Shang‐Yeh Lu; Shih‐Chieh Liao; Kuan‐Ho Lin et al.
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Diosgenin Attenuates Myocardial Cell Apoptosis Triggered by Oxidative Stress through Estrogen Receptor to Activate the PI3K/Akt and ERK Axes

The American Journal of Chinese Medicine
2023-01 | Journal article
DOI: 10.1142/s0192415x23500556
Part of ISSN: 0192-415X
Part of ISSN: 1793-6853
Contributors: Michael Yu-Chih Chen; Bruce Chi-Kang Tsai; Wei-Wen Kuo; Chia-Hua Kuo; Yueh-Min Lin; Dennis Jine-Yuan Hsieh; Pei-Ying Pai; Shih-Chieh Liao; Shang-En Huang; Shin-Da Lee et al.
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Angiotensin II prompts heart cell apoptosis via AT1 receptor-augmented phosphatase and tensin homolog and miR-320-3p functions to enhance suppression of the IGF1R-PI3K-AKT survival pathway

Journal of Hypertension
2022-12 | Journal article
DOI: 10.1097/hjh.0000000000003285
Part of ISSN: 0263-6352
Part of ISSN: 1473-5598
Contributors: Shang-Yeh Lu; Wei-Zhi Hong; Bruce Chi-Kang Tsai; Yu-Chun Chang; Chia-Hua Kuo; Thomas G. Mhone; Ray-Jade Chen; Wei-Wen Kuo; Chih-Yang Huang
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Estimating the impact of drug addiction causes heart damage

Drug and Chemical Toxicology
2022-10-10 | Journal article
DOI: 10.1080/01480545.2022.2122984
Part of ISSN: 0148-0545
Part of ISSN: 1525-6014
Contributors: Sheng-Huang Chang; Pei-Ying Pai; Chiung-Hung Hsu; Shibu Marthandam Asokan; Bruce Chi-Kang Tsai; Wen-Tsan Weng; Wei-Wen Kuo; Tzu-Ching Shih; Hui-Chuan Kao; William Shao-Tsu Chen et al.
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Neuroprotective Effects of Probiotic Lactobacillus reuteri GMNL-263 in the Hippocampus of Streptozotocin-Induced Diabetic Rats

Probiotics and Antimicrobial Proteins
2022-08-31 | Journal article | Writing - original draft, Data curation, Formal analysis, Writing - review & editing
DOI: 10.1007/s12602-022-09982-w
Part of ISSN: 1867-1306
Part of ISSN: 1867-1314
Contributors: Bruce Chi-Kang Tsai
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Epigallocatechin-3-Gallate Pretreatment Improves Autologous Adipose-derived Stem Cells Against Rheumatoid Arthritis-induced Neuroinflammation in the Brain of Collagen-induced Rats

Neurotoxicity Research
2022-07-13 | Journal article
DOI: 10.1007/s12640-022-00544-0
Part of ISSN: 1029-8428
Part of ISSN: 1476-3524
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Curcumin-Pretreated Adipose-Derived Stem Cells Enhance the Neuroprotective Ability to Repair Rheumatoid Arthritis-Induced Damage in the Rat Brain

The American Journal of Chinese Medicine
2022-06-22 | Journal article
DOI: 10.1142/s0192415x22500549
Part of ISSN: 0192-415X
Part of ISSN: 1793-6853
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Arecoline induces cardiotoxicity by upregulating and activating cardiac hypertrophy-related pathways in Sprague–Dawley rats

Chemico-Biological Interactions
2022-02 | Journal article
DOI: 10.1016/j.cbi.2022.109810
Part of ISSN: 0009-2797
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Exercise renovates H2S and Nrf2-related antioxidant pathways to suppress apoptosis in the natural ageing process of male rat cortex

Biogerontology
2021-07-12 | Journal article
DOI: 10.1007/s10522-021-09929-8
Part of ISSN: 1389-5729
Part of ISSN: 1573-6768
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Arecoline induces heart injure via Fas/Fas ligand apoptotic pathway in heart of Sprague–Dawley rat

Environmental Toxicology
2021-04-30 | Journal article
DOI: 10.1002/tox.23153
Part of ISSN: 1520-4081
Part of ISSN: 1522-7278
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Heat-Killed Lactobacillus reuteri GMNL-263 Inhibits Systemic Lupus Erythematosus–Induced Cardiomyopathy in NZB/W F1 Mice

Probiotics and Antimicrobial Proteins
2021-02 | Journal article
DOI: 10.1007/s12602-020-09668-1
Part of ISSN: 1867-1306
Part of ISSN: 1867-1314
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Diabetes-induced cardiomyopathy is ameliorated by heat-killed Lactobacillus reuteri GMNL-263 in diabetic rats via the repression of the toll-like receptor 4 pathway

European Journal of Nutrition
2021-02-08 | Journal article
DOI: 10.1007/s00394-020-02474-z
Part of ISSN: 1436-6207
Part of ISSN: 1436-6215
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Hyperglycemia-Induced Cardiac Damage Is Alleviated by Heat-Inactivated Lactobacillus reuteri GMNL-263 via Activation of the IGF1R Survival Pathway

Probiotics and Antimicrobial Proteins
2021-02-01 | Journal article
DOI: 10.1007/s12602-021-09745-z
Part of ISSN: 1867-1306
Part of ISSN: 1867-1314
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

The soybean bioactive peptide VHVV alleviates hypertension-induced renal damage in hypertensive rats via the SIRT1-PGC1α/Nrf2 pathway

Journal of Functional Foods
2020-12 | Journal article
DOI: 10.1016/j.jff.2020.104255
Part of ISSN: 1756-4646
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Functional potato bioactive peptide intensifies Nrf2-dependent antioxidant defense against renal damage in hypertensive rats

Food Research International
2020-03 | Journal article
DOI: 10.1016/j.foodres.2019.108862
Part of ISSN: 0963-9969
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎

Targeted delivery of bio-synthetic lycopene by the bacterial carrier

Journal of the Taiwan Institute of Chemical Engineers
2016-02 | Journal article
DOI: 10.1016/j.jtice.2015.08.003
Part of ISSN: 1876-1070
Source: Self-asserted source
Bruce Chi-Kang Tsai
grade
Preferred source (of 3)‎
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